Wasted Hands Unilateral vs Bilateral (think of levels!) Unilateral Think of (no myopathy, got brachial plexus) Peripheral nerve (median, ulnar or combined) Mononeuropathy vs peripheral neuropathy (asymmetric involvement) Brachial plexus (trauma, tumor, radiation, Cx rib) C8-T1 root lesions (Cx spondylosis) Anterior Horn Cell (Poliomyelitis) Cervical cord Proceed as: Long case – as per protocol, check also neck and chest Short case On inspection, unilateral wasted hands noted Neurological hand screen Examine for ulnar and median nerve palsies. Check for sensory for nerve vs root (peripheral nerve vs brachial plexus) and no loss (ie anterior horn cell) Note sensory for ulnar, median and radial Note sensory of peripheral neuropathy Note dermatomal sensory Feel for thickened nerves, look for hypoaesthetic macules, fasciculations Look for scars in the axilla and neck (neck pain, tenderness), Cx rib Check function Requests Palpate for cervical rib and features of Pancoast’s tumor (dullness to percussion, Horner’s syndrome, hoarseness voice) Check for winging of scapula (for brachial plexus involvement) If brachial plexus Upper vs lower (wasting of muscles of hands) vs complete Surgical(Cx rib, Pancoast) vs medical cause(brachial neuritis) Test for proximal involvement Serratus anterior (winging of scapula on pushing against wall) ie C5,6,7 Supraspinatus (abduction of UL from hands by your side position) C5 Infraspinatus (elbow flexed and push backwards) C5 Rhomboids (hand on hip and push backwards) C4,5,6 Reflexes (inverted supinator jerk) Bilateral Think of Rule out the obvious (hand screen) RA, gouty hands Dystrophia myotonica Levels (got myopathy, maybe brachial plexus if bilateral Cx ribs) Distal myopathy (reflexes normal; rare), dystrophia myotonica Peripheral nerve lesions Combined CTS (see median nerve palsy) Combined ulnar and median nerve Leprosy (resorption, hypoaesthetic macule and thickened nerve) HMSN (look at the feet for pes cavus deformities, thickened nerves) Peripheral motor neuropathy (Not likely to be brachial plexus unless bilateral Cx ribs) Nerve roots Cervical spondylosis (inverted supinator jerk, increased jerks for high cervical cord lesions) Anterior Horn cell (no sensory loss) MND (fasciculations) Poliomyelitis SMA Spinal cord lesions Intramedullary (Syringomyelia – dissociated sensory loss) Extramedullary Request LL – spastic paraparesis ( if suspect Cx cord, MND) Lower cranial nerve (bulbar palsy – if suspect MND or syringomyelia) Proceed as Long case Proceed as per normal Examine or request to examine the neck (pain tenderness and pain on neck movements), chest, CNs and LLs accordingly Short case Neurological hand screen Median and ulnar nerve testing, and wrist drop( because this is also weak in C8 root lesions) Sensory – peripheral nerve vs neuropathy vs root Check the elbows for thickened nerves Look for fasciculations (peripheral nerve, neuropathy, MND), hypoaesthetic macules Inspect the neck Quick glance at the face (NG tube – bulbar palsy, LLs – HMSN) Check function Request for reflexes, percussion myotonia if deemed appropriate (if suspect Cx cord lesion or dystrophia myotonica) Questions What are the levels and causes? Disuse atrophy (RA hands) Myopathy (distal myopathies or dystrophia myotonica – usually forearms more affected) Peripheral neuropathy - motor (see causes in Neurology segment) Mononeuropathy Surgical, trauma or compression Mononeuritis multiplex, infection, inflammatory and ischaemic Brachial Plexus Surgical, trauma compression (Pancoast’s, Cx rib) Brachial neuritis Nerve root (Disc prolapse) Anterior Horn cell MND, poliomyelitis, SMA Spinal cord Intramedullary Extramedullary How would you Ix? Blood Ix according to causes as above Imaging – X-rays, CT or MRI of spine NCT/EMG What are the causes of a claw hand? Partial claw Ulnar nerve palsy (See Ulnar nerve) True Claw Non-neurological RA Severe Volkmann’s ischaemic contracture Neurological (5) Combined median and ulnar nerve Leprosy (reflexes present. Pain loss, thickened nerves) Lower brachial plexus ( C7-T1, selective loss of reflexes, pain loss) Poliomyelitis (reflexes selective, pain intact) Syringomyelia (reflexes absent, pain loss)