6. PUBLICATIONS 6.1 Editorials, Reviews, and Book Chapters 1. Smith MA, Eastell R, Kennedy NSJ, Nuki G, Reid DM, Strong JA, Tothill P. The assessment of osteoporosis by neutron activation analysis. Menczel J, Robin GC, Makin M, Steinberg R, eds. Osteoporosis. London: John Wiley and Sons, 1983; 4548. 2. Smith MA, Tothill P, Kennedy NSJ, Eastell R. Total body calcium by neutron activation analysis. Dixon AStJ, Russell RGG, Stamp TCB, eds. Osteoporosis, a Multidisciplinary Problem. London: Academic Press, 1983; 121-125. 3. Wahner HW, Eastell R, Riggs BL. Bone mineral density of the radius: where do we stand? (editorial) J Nucl Med 1985; 26: 1339-1341. 4. Eastell R, Riggs BL. Exercise, hypogonadism, and osteopenia (Editorial). J Am Med Assoc 1986; 256: 392-393. 5. Eastell R, Riggs BL. Treatment of osteoporosis (review). Obstet Gynecol Clinics N Amer 1987; 14: 77-88. 6. Eastell R, Riggs BL. New approaches to the treatment of osteoporosis (review). Clin Obstet Gynecol 1987; 30: 860-870. 7. Eastell R, Riggs BL. Endocrinology and aging: calcium metabolism and osteoporosis (review). Endocrinol Metab Clin North Am 1987; 16: 829-842. 8. Eastell R, Hay ID. Metabolic considerations: hypercalcemia of malignancy. In: Sim FH, ed. Diagnosis and Management of Metastatic Bone Disease: A Multidisciplinary Approach. New York: Raven Press, 1988; 147-152. 9. Eastell R, Heath H III, Kumar R, Riggs BL. Pathophysiology of osteoporosis. Hormonal factors: PTH, vitamin D, and calcitonin. In: Riggs BL, Melton LJ III, eds. Osteoporosis: Etiology, Diagnosis and Management. New York: Raven Press, 1988; 373-388. 10. Eastell R, Riggs BL. Diagnostic evaluation of osteoporosis (review). Endocrinol Metab Clin North Am 1988; 17: 547-572. 11. Eastell R, Heath H III. The hypocalcemic states: differential diagnosis and management. In: Coe FL, Favus MJ, eds. Disorders of Bone and Mineral Metabolism. New York: Raven Press, 571-586. 12. Peel NFA, Eastell R, Russell RGG. Osteoporosis in rheumatoid arthritis - The laboratory perspective. British Journal of Rheumatology 1991; 30: 84-85. 13. Peel NFA, Eastell R, Russell RGG. Markers of bone and collagen breakdown. In: Emery P (Editor). Balliere's Clinical Rheumatology Management of early inflammatory arthritis. Balliere Tindall, London 1992 6:351-372. 1 14. Blumsohn A, Eastell R. Prediction of bone loss in postmenopausal women. Eur J Clin Invest 1992; 22:764-766. 15. Cooper C, Eastell R. Bone gain and loss in premenopausal women. Br Med J 1993; 306:1357-1358. 16. Russell RGG, Colwell A, Hannon RA, Blumsohn A, Al-Dehaimi AW, Assiri AMA, Peel NFA, Eastell R. Biochemical measurements in pagets disease of bone. Seminars in Arthritis and Rheumatism 1994, Vol 23 4:240-241. 17. Peel NFA, Eastell R. Measurement of bone mass and turnover. Baillieres Clinical Rheumatology 1993, Vol. 7 3:479-498. 18. Eastell R: The role of calcium and exercise in the prevention of postmenopausal osteoporosis. Journal of Obstetrics and Gynaecology 1993; 13:S5-S7. 19. Eastell R. Investigation of metabolic bone disease. Medicine International 1994, Vol. 22: 190-194. 20. Eastell R. Biochemical Markers. Spine: State of the Art Reviews 1994; 8: 155-170. 21. Blumsohn A, Eastell R. Calcium supplementation and circadian rhythms of bone turnover. Challenges of Modern Medicine 1995, Vol 7: 273-277. 22. Evans C, Eastell R. Adaptation to high dietary sodium intake. Challenges of Modern Medicine 1995, Vol 7: 413-418. 23. Peel NFA, Eastell R. Osteoporosis (ABC of Rheumatology). British Medical Journal 1995, Vol 310:989-992. 24. Blumsohn A, Eastell R. Age-related factors (in bone loss). Osteoporosis: Etiology, diagnosis and management, second edition , Riggs BL, Melton LJ, eds. Raven Press, New York, Osteoporosis: Etiology, Diagnosis and Management 1995, 161-182. 25. Blumsohn A, Hannon RA, Eastell R.. Biochemical assessment of skeletal activity. Physical Medicine and Rehabilitation Clinics of North America, 1995, Vol 6, 3:483505. 26. Hannon RA, Eastell R. Biochemical markers of bone turnover. The Measurement of Metabolic Bone Disease, Tovey FI, Stamp TCB, eds. Parthenon Publishing, Carnforth, 1995, 21-47. 27. Eastell R. Management of corticosteroid-induced osteoporosis. J Int Med, 1995; 237: 439-447. 28. Eastell R. Determination of bone resorption. Kinetic Models of Trace Element and Mineral Metabolism during Development. Eds Siva Subramanian KN, Wastney ME, CRC Press, 1995, 355-358. 29. Eastell R, Blumsohn A. New tests for the assessment of bone turnover in osteoporosis. Proceedings UK NEQAS Meeting l994. Endocrine Aspects of the Menopause, 87-93. 2 30. Eastell R. Forearm Fracture. Bone 1996; Vol 18, 3:203S-207S (Supplement). 31. Eastell, R. Workshop Session V. Management of corticosteroid-induced osteoporosis. Osteoporosis Int 1996, Suppl 2:S36-S37. 32. Eastell R. Assessment of bone density and bone loss. Osteoporosis Int 1996, Suppl 2:S3-S5. 33. Eastell R, Devogelaer JP, Peel NFA, Gill C, Bax DE, Nagant de Deuxchaisnes C, Russell RGG. A double-blind placebo-controlled study to determine the effects of risedronate on bone loss in glucocorticoid-treated rheumatoid arthritis. Proceedings of the 1996 World Congress on Osteoporosis. Osteoporosis 1996, 391-393. 34. Vinholes J, Coleman R, Eastell R. Effects of bone metastases on bone metabolism: implications for diagnosis, imaging and assessment of response to cancer treatment. Cancer Treatment Reviews 1996, vol 22; 289-331. 35. Seibel MJ, Baylink DJ, Farley JR, Epstein S, Yamauchi M, Eastell R, Pols HAP, Raisz LG, Gundberg CM. Basic science and clinical utility of biochemical markers of bone turnover - A congress report. Exp Clin Endocrinol Diabetes 1997, vol 105; 125-133. 36. Eastell R. Osteoporosis. The Medicine Group (Journals) 1997, vol 25; 76-80. 37. Eastell R, Blumsohn A. The value of biochemical markers of bone turnover in osteoporosis. J Rheum 1997, vol 24; 6:1215-1217. 38. Blumsohn A, Eastell R. The performance and utility of biochemical markers of bone turnover: do we know enough to use them in clinical practice? Ann Clin Biochem 1997; 34: 449-459. 39. Eastell R, Riggs B L. Vitamin D and Osteoporosis. Vitamin D, Eds Feldman D, Glorieux FH, Pike JW. Academic Press, USA. 1997, 695-711. 40. Eastell R, Boyle IT, Compston J et al. Management of male osteoporosis: report of the UK Consensus Group. Quarterly Journal of Medicine 1998; 91: 71-92. 41. Eastell R, Peel N. Osteoporosis. Journal of the Royal College of Physicians of London 1998, vol 32; 1:14-18. 42. Eastell R. Treatment of postmenopausal osteoporosis. The New England Journal of Medicine 1998, vol 338: 11;736-746. 43. Hannon R, Eastell R. Bone metabolism and osteoporosis. J Br Meno Soc 1998, vol 4, 3:103-106. 44. Jones N, Lambert HL, Eastell R, Barker ME. Bone growth in childhood and adolewcence: the interpretation of dietary supplementation trials. Serono Symposia USA, Nutritional Aspects of Osteoporosis. Eds P Burckhardt, B Dawson-Hughes, R Heaney, 1998 Springer-Verlag New York, Inc. p50-55. 3 45. Eastell R, Whybro A, Jagger H, Barker ME. Adaptation to young men to high phosphate intake. Serono Symposia USA, Nutritional Aspects of Osteoporosis. Eds P Burckhardt, B Dawson-Hughes, R Heaney, 1998 Springer-Verlag New York, Inc. p185-190. 46. Eastell R, Reid DM, Compston J, et al. A UK Consensus Group on management of glucocorticoid-induced osteoporosis: an update. J Int Med 1998, 244:271-292. 47. Eastell R, Machado ABC. Clinical application of biochemical markers of bone turnover in osteoporosis. CME Bulletin Endocrinology & Diabetes 1999, vol 2; 1:4-6. 48. Eastell R. Biochemical markers of bone turnover in Paget’s disease of bone. Bone 1999, vol 24;5:49S-50S. 49. Eastell R. Optimising the benefits of hormone replacement therapy for osteoporosis. J Br Meno Soc 1999, vol 5, supplement 1:20-23. 50. Hart SM, Eastell R. Biochemical markers of bone turnover. Current Opinion in Nephrology and Hypertension 1999, vol 8; 421-427. 51.Meunier P, Delmas P, Eastell R et al. International Committee for Osteoporosis Clinical Guidelines. Diagnosis and Management of osteoporosis in postmenopausal women: Clinical Guidelines. Clinical Therapeutics 1999, 21(6):1025-1044. 52. Eastell R, Hannon R.A. Biochemical markers of bone turnover. Treatment of the postmenopausal woman: Basic and clinical aspects. Second edition. Eds Rogerio A Lobo 1999. Lippincott Williams & Wilkins, Philadelphia. 293-303. 53. Eastell R, Naylor KE. Calcium homeostasis in pregnancy. Cherry and Merkatz's Complications of pregnancy. Fifth edition. Ed W R Cohen 1999. Lippincott Williams & Wilkins, Philadelphia. 451-463. 54. Ingle BM, Eastell R. Ultrasound in clinical Practice. Quantitative Ultrasound: Assessment of osteoporosis and bone status 1999. Eds. CF Njeh, D Hans, T Fuerst, CC Gluer, HK Genant.Martin Dunitz, London. 325-336. 55. Lee AJ, Hodges S, Eastell R. Measurement of osteocalcin. Annals of Clinical Biochemistry 2000, vol 37, 432-446. 56. Clowes JA, Eastell R. The role of bone turnover markers and risk factors in the assessment of osteoporosis and fracture risk. Bailliere's Clin Endo & Metab 2000, vol 14, 2:213-232. 57. Hannon R, Eastell R. Preanalytical variability of biochemical markers of bone turnover. Osteoporosis International 2000, suppl 6:S30-44. 58. Eastell R. Risedronate: Review of efficacy and safety in postmenopausal and glucocorticoid-induced osteoporosis. Osteologia Osteology 2000, vol 3:4;314-317. 59.Delmas PD, Eastell R, Garnero P et al. The use of biochemical markers of bone turnover in osteoporosis. Osteoporosis International 2000, suppl 6:S2-17. 4 60.Pereda CA, Eastell R. Calcium supplements alone and in association with antiresorptive drugs in osteoporosis. Primary and Secondary Preventive Nutrition 2001, Eds A Bendich and RJ Deckelbaum, Humana Press Inc, Totowa NJ. 307-321. 61.Eastell R, Bainbridge PR. Bone turnover markers for monitoring antiresorptive therapy. Osteoporosis Review 2001, vol 9:1;1-5. 62.Eastell R. Definitions and interpretation of bone mineral density in a clinical context. Manual of bone densitometry measurements. Ed JN Fordham, Springer-Verlag 2001, 55-66. 63.Lambert H, Barker M, Eastell R. Calcium and bone mineral accretion in teenage girls: a review. Nutritional Aspects of Osteoporosis, 2001. Ed P Burckhardt, Academic Press, 23-32. 64.Smith CM, Coombs RC, Eastell R. Effect of nutrient intake on markers of bone turnover in preterm infants. Nutritional Aspects of Osteoporosis, 2001. Ed P Burckhardt, Academic Press. 43-48. 65.Clowes JA, Peel N, Eastell R. Glucocorticoid-induced osteoporosis. Current Opinion in Rheumatology, 2001. Lippincott Williams & Wilkins Inc. 326-332. 66.Eastell R. Risedronate: A new bisphosphonate for the prevention and treatment of osteoporosis. Clinical Geriatrics 2001, vol 9, 12:36-46. 67.Eastell R, Reid DM, Compston J et al. Secondary prevention of osteoporosis: When should a non-vertebral fracture be a trigger for action? Quarterly Journal of Medicine 2001, 94:575-597. 68.Eastell R. Effects of inhaled steroids on bone mineral density: are the conclusions misleading? IBMS BoneKey 2001, Nov 30 10.1138/ibmske;2001044. 69.Eastell R. Osteoporosis. Medicine 2001; 29:12:66-70. 70.Eastell R, Baumann M, Hoyle NR, Wieczorek L. Bone Markers: Biochemical and Clinical perspectives. Martin Dunitz: London, 2001. 71.Seibel MJ, Eastell R, Gundberg CM, Hannon R, Pols HAP. Biochemical markers of bone metabolism. Principles of Bone Biology, second edition, vol 2, 2002. Eds JP Bilezikian, LG Raisz, GA Rodan. Academic Press. 1543-1571. 72. Eastell R, Hart S. Bone turnover markers in clinical practice. Biomarkers of disease: An evidence-based approach, 2002. Eds AK Trull, LM Demers, DW Holt, A Johnston, JM Tredger, CP Price. Cambridge University Press. 73.Vesper HW, Demers LM, Eastell R, Garnero P, Kleerekoper M, Robins SP, Srivastava AK, Warnick GR, Watts NB, Myers GL. Related articles assessment and recommendations on factors contributing to preanalytical variability of urinary pyridinoline and deoxypyridinoline. Clinical Chemistry 2002, vol 48, 2:220-235. 74.Eastell R, Lambert H. Diet and healthy bones. Calcified Tissue International 2002; 70:400-4. 5 75.Eastell R, Lambert H. Strategies for skeletal health in the elderly. Proceedings of the Nutrition Society 2002, 61:173-180 76.Eastell R, Bainbridge PR. Bone turnover markers: Their place in the investigation of osteoporosis. Contemporary Endocrinology: Osteoporosis: Pathophysiology and Clinical Management. Eds ES Orwoll, M Bliziotes. Human Press Inc, Totowa NJ. 2002, 185-197. 77.Eastell R. Osteoporosis. Oxford Text Book of Endocrinology and Diabetes. Eds. JAH Wass, SM Shalet, Oxford University Press, 2002, 665-675. 78. Hannon RA, Eastell R. Biochemical markers of bone turnover and fracture prediction. Journal of British Menopause Society, March 2003, 10-14. 79. Eastell R, Adams J. Bone mineral density and bone markers subprotocol. History and advancement of Anastrozole in the treatment of breast cancer. Eds A Buzdar and M Baum. The Royal Society of Medicine Press 2003, 71-75. 80. Eastell R. Management of osteoporosis due to ovarian failure. Med Pediatr Oncol 2003, Sep 41(3):222-7. 81. Eastell R, Bainbridge PR. Laboratory assessment of skeletal status. Atlas of osteoporosis, second edition. Ed ES Orwoll, Series Ed SG Korenman. Current Medicine Inc, Philadelphia 2003, 77-82. 82. Eastell R. Pathogenesis of postmenopausal osteoporosis. Primer on the metabolic bone diseases and disorders of mineral metabolism. 5th edition. Ed MJ Favus. American Society for Bone and Mineral Research 2003, 314-316. 83. Peel N, Eastell R. Osteoporosis (ABC of Rheumatology). British Medical Journal. 3rd edition. Ed ML Snaith. BMJ Publishing Group Limited, 2004 :45-49. 84. Adhikari M, Morris BW, Eastell R, Blumsohn A. A placebo controlled randomized trial of chromium picolinate supplementation on indices of bone and calcium metabolism in healthy women. Nutritional Aspects of Osteoporosis. 2nd edition. Elsevier Science, 2004:141-151. 85. Eastell R. New management strategies for osteoporosis. Horizons in Medicine 16. Ed. J Franklyn. Royal College of Physicians of London 2004:63-68 86. Eastell R, Naylor KE, Cooper AM. Pathogenesis of transplantation bone disease: A unifying hypothesis. Bone Disease of Organ Transplantation. Eds J Compston and E Shane. Elsevier Academic Press 2005:209-217 87. Eastell R, Riggs BL. Vitamin D and Osteoporosis. Vitamin D, 2nd edition. Eds D Feldman, J Wesley Pike, and F H Glorieux. Elsevier Academic Press 2005: 1101-1120 88. Eastell R. Role of oestrogen in the regulation of bone turnover at the menarche. Journal of Endocrinology 2005; 185:223-234 6 89. Eastell R. Calcium requirements during treatment of osteoporosis in women. Preventive Nutrition, The comprehensive guide for health professionals. 3rd edition. Eds. A Bendich & R J Deckelbaum. Humana Press Inc 2005: 425-431 90. Ferrar L, Jiang G, Adams J, Eastell R. Identification of vertebral fractures: An Update. Osteoporosis International 2005, vol 16:7;717-728 91. Eastell R, Delmas PD. How to interpret surrogate markers of efficacy in osteoporosis. Letter to the Editor. J Bone Miner Res 2005, vol 20:7;1261-1262 Author reply 1263-1264 92. Eastell R, Hannon R. Long-term effects of aromatase inhibitors on bone. J Steroid Biochem Mol Biol 2005, vol 95(1-5):151-154 93. Clowes JA, Khosla S, Eastell R. Potential role of pancreatic and enteric hormones in regulating bone turnover. J Bone Miner Res 2005, vol 20:90;1497-1506 94. Eastell R. Management of bone health in postmenopausal women. Hormone Research 2005, 64 (suppl 2):76-80 95. Eastell R. Osteoporosis. Medicine 2005 ; 33 :12 :61-65 96. Rogers A, Eastell R. Circulating osteoprotegerin and receptor activator for nuclear Factor kappaB ligand : clinical utility in metabolic bone disease assessment. J Clin Endo Metab 2005, vol 90 :11;6323-6331 97. Shetty N, Hamer AJ, Stockley I, Eastell R, Wilkinson JM. Effect of bisphosphonates on Periprosthetic bone mineral density after total joint arthroplasty. Letter to the Editor – J Bone & Joint Surgery 2005 , vol 87 :11 ;2589-2590 98. Clowes J, Eastell R. Corticosteroid-induced osteoporosis. Osteoporosis : State of the Art. Ed : N Arden. Remedica 2006, 185-201 99. Eastell R. Pathogenesis of postmenopausal osteoporosis. Primer on the metabolic bone diseases and disorders of mineral metabolism. 6th edition. Ed MJ Favus. American Society for Bone and Mineral Research 2006, 259-262. 100.Naylor KE, Eastell R. Measurement of biochemical markers of bone formation.dynamics of bone and cartilage metabolism. 2nd edition. Eds MJ Seibel, SP Robins, JP Bilezikian. Academic Press 2006, 529-540 101.Eastell R. Commentary - Does warfarin increase the risk of osteoporotic fracture ? Nature Clinical Practice. Endocrinology & Metabolism 2006, vol 2 :9 ;485 102.Eastell R. Investigating suspected osteoporosis. Women’s Health Medicine 2006, vol 3 :4 ;161-164 103. Eastell R. Treating Osteoporosis. Women’s Health Medicine 2006, vol 3 :4,171-172 104.Amin S, Eastell R, Clowes JA. Risk factors for osteoporosis and fractures in men and women. Best Practice & Research Compendium – Osteoporosis. Eds C Cooper & A D Woolf. Elsevier 2006, 63-77 7 105.Hannon RA, Eastell R. Bone markers and current laboratory assays. Cancer Treat Rev 2006, suppl 1 :7-14 106.Eastell R. Breast cancer and the risk of osteoporotic fracture : A Pardox. J Clin Endo Metab 2007, vol 92 ;1 :42-43 6.2 Original Publications in Referred Journals 1. Corrall RJM, Grieve J, Sloan EG, Brooks AP, Martyn CN, Eastell R, Ashby JP. A simple low-magnesium diet. J Human Nutr 1980; 34: 5-8. 2. Smith MA, Eastell R, Kennedy NSJ, McIntosh LV, Simpson JD, Strong JA, Tothill P. Measurement of spinal calcium by in vivo neutron activation analysis in osteoporosis. Clin Phys Physiol Meas 1981; 2: 45-48. 3. Kennedy NSJ, Eastell R, Ferrington CM, Simpson JD, Smith MA, Strong JA, Tothill P. Total body neutron activation analysis of calcium: calibration and normalization. Phys Med Biol 1982; 27: 316-334. 4. Eastell R, Kennedy NSJ, Smith MA, Simpson JD, Strong JA, Tothill P. The assessment of postmenopausal osteoporosis by total-body neutron activation analysis. Metab Bone Dis Rel Res 1983; 5: 65-67. 5. Kennedy NSJ, Eastell R, Smith MA, Tothill P. Normal levels of sodium and chlorine by neutron activation analysis. Phys Med Biol 1983; 28: 215-221. 6. Eastell R, Edmonds CJ. Hyponatraemia associated with trimethoprim and a diuretic. Br Med J 1984; 289: 1658-1659. 7. Eastell R. Calcium absorption and achlorhydria (Letter to the Editor). N Engl J Med 1985; 313: 1481-1482. 8. Eastell R, Ashby JP. An unhelpful C-peptide suppression test in a patient with insulinoma. Br Med J 1985; 290: 286. 9. Eastell R, Edmonds CJ, de Chazal RCS, McFadyen IR. Prolonged hypoparathyroidism presenting eventually as second trimester abortion. Br Med J 1985; 291: 955-956. 10. Eastell R, Kennedy NSJ, Smith MA, Tothill P, Anderton JL. Changes in total body calcium after renal transplantation: effect of low-dose steroid regime. Nephron 1985; 40:139-142. 11. Eastell R, Kennedy NSJ, Smith MA, Tothill P, Edwards CRW. Changes in total body calcium following surgery for primary hyperparathyroidism. Bone 1986; 7:269-272. 8 12. Eastell R, Riggs BL, Kumar R. A primed-infusion technique for rapid estimation of the metabolic clearance rate of 1,25-dihydroxyvitamin D3. Am J Physiol 1987; 253: E246E250. 13. Eastell R, Delmas PD, Hodgson SF, Eriksen EF, Mann KG, Riggs BL. Bone formation rate in older normal women: concurrent assessment with bone histomorphometry, calcium kinetics, and biochemical markers. J Clin Endocrinol Metab 1988; 67: 741748. 14. Eastell R, Wahner HW, O'Fallon WM, Amadio PC, Melton LJ, Riggs BL. Unequal decrease in bone density of lumbar spine and ultradistal radius in Colles' and vertebral fracture syndromes. J Clin Invest 1989; 83:168-174. 15. Eastell R, Dewanjee MK, Riggs BL. Comparison of polyethylene glycol and chromium-51 chloride as nonabsorbable stool markers in calcium balance studies. Bone and Mineral 1989; 6:95-105. 16. Eastell R, Vieira NE, Yergey AL, Riggs BL. One-day test using stable isotopes to measure true fractional calcium absorption. J Bone Min Res 1989; 4:463-468. 17. Eastell R, Riggs BL, Wahner HW, O'Fallon WM, Amadio PC, Melton LJ III. Colles' fracture and bone density of the ultradistal radius. J Bone Min Res 1989; 4:607-613. 18. Eriksen EF, Hodgson SF, Eastell R, Cedel SL, O'Fallon WM, Riggs BL. Cancellous bone remodelling in type I (postmenopausal) osteoporosis: quantitative assessment of rates of formation, resorption and bone loss at tissue and cellular levels. J Bone Min Res, 1990; 5:311-320. 19. Eastell R, Mosekilde Li, Hodgson SF, Riggs BL. Proportion of human vertebral body bone that is cancellous. J Bone Miner Res, 1990; 5:1237-1241. 20. Eastell R, Cedel SL, Wahner HW, Riggs BL, Melton LJ III. Classification of vertebral fractures. J Bone Miner Res, 1991; 6:207-215. 21. Calvo MS, Eastell R, Offord KP, Bergstralh EJ, Burritt MF. Circadian variation in ionized calcium and intact parathyroid hormone: evidence for sex differences in calcium homeostasis. J Clin Endocrinol Metab, 1991; 72:69-76. 22. Eastell R, Yergey AL, Vieira NE, Cedel SL, Kumar R, Riggs BL. Interrelationship among vitamin D metabolism, true calcium absorption, parathyroid function and age in women: Evidence of an age-related intestinal resistance to 1,25-dihydroxyvitamin D action. J Bone Miner Res, 1991; 6:125-132. 23. Eastell R, Dickson ER, Hodgson SF, Wiesner RH, Porayko MK, Wahner HW, Cedel SL, Riggs BL, Krom RAF. Rates of vertebral bone loss before and after liver transplantation in women with primary biliary cirrhosis. Hepatology, 1991; 14:296300. 24. Ebeling PR, Butler PC, Eastell R, Rizza RA, Riggs BL. The nocturnal increase in growth hormone is not the cause of increase in serum osteocalcin. J Clin Endocrinol Metab, 1991; 73:368-372. 9 25. Eastell R, Calvo MS, Burritt MF, Offord KP, Russell RGG, Riggs BL. Abnormalities in circadian patterns of bone resorption and renal calcium conservation in type I osteoporosis. J Clin Endocrinol Metab, 1992; 74:487-494. 26. Eastell R, Simmons P, Colwell A, Assiri A, Burritt MF, Russell RGG, Riggs BL. Nyctohemeral changes in bone turnover assessed by serum bone Gla-protein and urinary deoxypyridinoline excretion - Effect of growth and aging. Clinical Science. 1992; 83:375-382. 27. Eastell R, Vieira NE, Yergey AL, Wahner HW, Silverstein MN, Kumar R, Riggs, BL. Pernicious anaemia as a risk factor for osteoporosis. Clinical Science, 1992; 82:681685. 28. Goerss JB, Kim CH, Atkinson EJ, Eastell R, O'Fallon WM, Melton LJ III. Risk of fractures in patients with pernicious anemia. J Bone Miner Res. 1992; 7:573-579. 29. Aaron JE, Abbas SK, Colwell A, Eastell R, Oakley BA, Russell RGG, Care AD. Parathyroid gland hormones in the skeletal development of the ovine foetus: the effect of parathyroidectomy with calcium and phosphate infusion. Bone & Mineral 1992; 16:121-129. 30. Hassager C, Colwell A, Assiri AMA, Eastell R, Russell RGG, Christiansen C. Effect of menopause and hormone replacement therapy on urinary excretion of pyridinium crosslinks" A longitudinal and cross-sectional study. Clin Endocrinol 1992; 37:45-50. 31. O'Neill TW, White J, Eastell R, Silman AJ. The influence of sex on morphometric indices of vertebral deformity. J Ortho Rheumatol 1993,6:29-32 32. Jerome CP, Colwell A, Eastell R, Russell RGG, Trechsel U. The effect of rat parathyroid hormone (1-34) infusion on urinary 3-hydroxypyridinium crosslink excretion in the rat. Bone Miner 1992; 19:117-125 33. Peel NFA, Johnson A, Barrington NA, Smith TWD, Eastell R. Impact of anamalous vertebral segmentation on measurements of bone mineral density. J Bone Miner Res 1993; 8:719-724. 34. Colwell A, Russell RGG, Eastell R. Factors affecting the assay of urinary 3-hydroxy pyridinium crosslinks of collagen as markers of bone resorption. Eur J Clin Invest 1993, 23:341-349. 35. Eastell R, Robins SP, Colwell A, Assiri AMA, Riggs BL, Russell RGG. Evaluation of bone turnover in type I osteoporosis using biochemical markers specific for both bone formation and bone resorption. Osteoporosis Int 1993; 3:255-260. 36. Gough A, Peel N, Eastell R, Holder RL, Lilley J, Emery P. Excretion of pyridinium crosslinks correlates with disease-activity and appendicular bone loss in early rheumatoid-arthritis. Annals of Rheumatic Diseases 1994; Vol 53 No.1 PP.14-17. 37. Peel NFA, Al-Dehaimi A, Colwell A, Russell RGG, Eastell R. Sulphasalasine may interfere with HPLC assay for urinary pyridinium crosslinks. Clin Chem 1994 Vol 40 1:167-168. 10 38. Bell NH, Hollis BW, Shary JR, Eyre DR, Eastell R. Diclofenac sodium inhibits bone resorption in postmenopausal women. Am J Med 1994; Vol 96 3:349-353. 39. Hamdy NAT, Papapoulos SE, Colwell A, Eastell R, Russell RGG. Urinary collagen crosslink excretion in better index of bone resorption than hydroxyproline in Paget's disease of bone. Bone Miner 1993; 22:1-8. 40. Hodgson SF, Dickson ER, Eastell R, Eriksen EF, Bryant SC, Riggs BL. Rates of cancellous bone remodelling and turnover in osteopenia associated with primary biliary-cirrhosis. Bone 1993 Vol.14 No.6 PP.819-827. 41. Peel NFA, Eastell R. Diagnostic-value of estimated volumetric bone-mineral density of the lumbar spine in osteoporosis. J Bone Miner Res 1994 Vol. 9 No. 3 PP. 317-320 42. Blumsohn A, Hannon RA, Wrate R, Barton J, Al-Dehaimi AW, Colwell A, Eastell R. Biochemical markers of bone turnover in girls during puberty. Clin Endocrinol 1994, Vol 40 5: 663-670. 43. Melton LJ, Lane AW, Cooper C, Eastell R, OFallon WM, Riggs BL. Prevalence and incidence of vertebral deformities. Osteoporosis Int. 1993; 3:113-119. 44 . Blumsohn A, Herrington K, Hannon RA, Shao P, Eyre DR, Eastell R: The effect of calcium supplementation on the circadian rhythm of bone resorption. J Clin Endocrinol Metab 1994; 79:730-735. 45. Blumsohn A, Morris B, Eastell R: Stable strontium absorption as a measure of intestinal calcium absorption: comparison with the double radio-tracer calcium absorption test. Clin Sci 1994; 87:363-368. 46. Peel NFA, Barrington NA, Smith TWD, Eastell R: Distal forearm fracture as a risk for vertebral osteoporosis. Brit Med J 1994; 308:1543-1544. 47. Peel NFA, Spittlehouse AJ, Bax DE, Eastell R. Bone mineral density of the hand in rheumatoid arthritis. Arthritis & Rheumatism 1994, Vol 37; 7:983-991. 48. Cummings SR, Melton LJ III, Felsenberg D, Allander E, Black D, Cooper C, Dutta SN, Eastell R, Epstein R, Genant HK, LeidigBruckner G, Kanis J, Karpf D, Kleerekoper M, McCloskey E, Minne HW, Nelson D, ONeil T, Orwwell E, et al. Assessing vertebral fractures. J Bone Miner Res l995, Vol 10; 4:518-523. 49. Blumsohn A, Hannon RA, Eastell R. Apparent instability of osteocalcin in serum as measured with different commercially available immunoassays. Clin Chem l995, Vol 41; 2:318-319. 50. Peel NFA, Eastell R. Comparison of rates of bone loss from the spine using two manufacturer's densitometers. J Bone Miner Res 1995, Vol 10; 11:17961801. 51. Blumsohn A, Naylor KE, Assiri AMA, Eastell R. Different responses of biochemical markers of bone resorption to bisphosphonate therapy in Paget's disease. Clin Chem 1995, Vol 41; 11:1592-1598. 11 52. Lakatos P, Blumsohn A, Eastell R, Tarjan G, Shinoda H, Stern PH. Circadian rhythm of bone resorbing activity in human serum. J Clin Endocrinol Metab 1995, Vol 80; 11:3185-3190. 53. Blumsohn A, Colwell A, Naylor KE, Eastell R. The effect of ultraviolet light and gamma irradiation on the stability of pyridinolines and telopeptides of type I collagen in urine. Clin Chem 1995; Vol 41, 8: 1195-1197. 54. Price JS, Jackson B, Wilson AM, Eastell R, Russell RGG, Lanyon LE, Goodship AE. The response of the skeleton to physical training: a biochemical study in horses. Bone 1995,Vol 17, 3:221-227. 55. Price JS, Jackson B, Wilson AM, Eastell R, Russell RGG, Lanyon LE, Goodship AE. Age-related changes in biochemical markers of bone metabolism in horses. Equine Veterinary Journal 1995; Vol 27:201-207. 56. Peel NFA, Moore DJ, Barrington NA, Bax DE, Eastell R. Risk of vertebral fracture and relationship to bone mineral density in steroid-induced rheumatoid arthritis. Ann Rheum Dis 1995; Vol 54:801-806. 57. Peel NFA, Smith AG, Hannon RA, Eastell R. Rate of bone loss from the lumbar spine in women with distal forearm fracture. Br Med J 1996; Vol 312:1457. 58. Peel NFA, Barrington NA, Blumsohn A, Colwell A, Hannon R, Eastell R. Bone mineral density and bone turnover in spinal osteoarthrosis. Ann Rheum Dis 1995, Vol 54:867-871. (Extended report) 59. Peel NFA, Barrington NA, Austin CA, Eastell R. Paget's Disease in patient with ankylosing spondylitis - A diagnostic dilemma. Br J Rheum 1996, Vol 35:1011-1014. 60. Colwell A, Hamer A, Blumsohn A, Eastell R. To determine the effects of UV, natural light and ionising radiation on pyridinium crosslinks in bone and urine using HPLC. Eur J Clin Invest 1996, Vol 26,:1107-1114. 61. Guo C-Y, Thomas WEG, Al-Dehaimi AW, Assiri AMA, Eastell R. Longitudinal changes of bone mineral density and bone turnover in postmenopausal women with primary hyperparathyroidism. J Clin Endocrinol Metab 1996. Vol 81,10:3487-3491. 62. Vinholes J, Guo C-Y, Purohit OP, Eastell R, Coleman RE. Metabolic effects of pamidronate in patients with metastatic bone disease. Br J Cancer 1996; Vol 73, 10891095. 63. O’Neill TW, Felsenberg D, Varlow J,…… Eastell R, Woolf AD. The prevalence of vertebral deformity in European men and women: The European Vertebral Osteoporosis Study. J Bone Miner Res 1996, Vol 7, 7:1010-1018 64. Colwell A, Eastell R. The renal clearance of free and conjugated pyridinium crosslinks of collagen. J Bone Miner Res 1996, Vol 11, 12:1976-1980. 65. Guo C-Y, Weetman AP, Eastell R. Bone turnover and bone mineral density in patients with congential adrenal hyperplasia. Clin Endo 1996; Vol 45, 535-541. 12 66. Guo C-Y, Jones HT, Eastell R. Treatment of isolated hypogonadotrophic hypogonadism effect: on bone mineral density and bone turnover. J Clin Endo Metab 1997, Vol 82, 2:658-665 67. Cooper C, Fall C, Egger P, Hobbs P, Eastell R, Barker D. Growth in infancy and bone mass in later life. Ann Rheum Dis 1997, Vol 56, 1:17-21. 68. Vinholes J, Guo CY, Purohit OM, Eastell R, Coleman RE. Evaluation of new bone resorption markers in a randomised comparison of pamidronate or clodronate for hypercalcemia of malignancy. J Clin Oncol 1997, Vol 15, 1:131-138. 69. Eastell R. Colwell A, Hampton L, Reeve J. Biochemical markers of bone resorption compared with estimates of bone resorption from radiotracer kinetic studies in osteoporosis. J Bone Miner Res 1997, Vol 12, 1:59-65. 70. Guo C-Y, Weetman AP, Eastell R. Longitudinal changes of bone mineral density and bone turnover in postmenopausal women on thyroxine. Clin Endo l997; Vol 46, 301307. 71. Peacey SR, Guo C-Y, Robinson AM, Price A, Giles MA, Eastell R, Weetman AP. Glucocorticoid replacement therapy: are patients over treated and does it matter. Clin Endo 1997; vol 46, 255-261. 72. Evans CEL, Chughtai AY, Blumsohn A, Giles M, Eastell R. The effect of dietary sodium on calcium metabolism in premenopausal and postmenopausal women. Euro J Clin Nutr 1997; vol 51, 394-399. 73. Cadogan J, Eastell R, Jones N, Barker ME. Milk intake and bone mineral acquisition in adolescent girls: A randomised, controlled intervention trial. Br Med J 1997, vol 315, 1255-1260. 74. Vinholes JJF, Purohit OM, Abbey ME, Eastell R, Coleman RE. Relationships between biochemical and symptomatic response in a double-blind randomised trial of pamidronate for metastatic bone disease. Annals of Oncology 1997, vol 8, 1243-1250. 75. Whybro A, Jagger H, Barker M, Eastell R. Phosphate supplementation in young men: lack of effect on calcium homeostasis and bone turnover. Euro J Clin Nutr 1998, vol 52, 29-33. 76. Guo CY, Johnson A, Locke TJ, Eastell R. Mechanisms of bone loss after cardiac transplantation. Bone 1998, 22; 3:267-271. 77. Spittlehouse AJ, Smith TWD, Eastell R. Bone loss around 2 different types of hip prostheses. J Arthroplasty 1998, vol 13, 4:422- 427. 78. Hannon R, Blumsohn A, Naylor K, Eastell R. Response of biochemical markers of bone turnover to hormone replacement therapy: impact of biological variability, J Bone and Miner Res 1998, vol 13, 7:1124-1133. 79. Rogers A, Eastell R. Effects of estrogen therapy of postmenopausal women on cytokines measured in peripheral blood. J Bone and Miner Res 1998, vol 13, 10:15771586. 13 80. Cadogan J, Blumsohn A, Barker ME, Eastell R. A longitudinal study of bone gain in pubertal girls: anthropometric and biochemical correlates. J Bone and Miner Res 1998, vol 13, 10:1602-1612. 81. Emslander HC, Sinaki M, Muhs JM, Chao EYS, Wahner HW, Bryant SC,Riggs BL, Eastell R. Bone mass and muscle strength in female college athletes (runners and swimmers). Mayo Clinic Proceedings 1998, vol 73, 12:1151-1160. 82. Naylor KE, Eastell R, Shattuck KE, Alfrey AC, Klein GL. Bone turnover in preterm infants. Pediatric Research 1999, vol 45, 3:363-366. 83. Machado ABC, Hannon R, Eastell R. Monitoring alendronate therapy for osteoporosis. J Bone and Miner Res 1999, vol 14, 4:602-608. 84. Hughes JA, Conry BG, Male SM, Eastell R. One year prospective open study of the effect of high dose inhaledsteroids, fluticasone propionate, and budesonide on bone markers and bone mineral density. Thorax 1999,54; 3:223-229. 85. Al-Dehaimi AW, Blumsohn A, Eastell R. Serum galactosyl hydroxylysine as a biochemicalmarker of bone resorption. Clinical Chemistry 1999, 45; 676-681. 86. Fatayerji D, Eastell R. Age-related changes in bone turnover in men. J Bone Miner Res 1999, vol 14, 7:1203-1210. 87. Walls J, Assiri A, Howell A, Rogers E, Ratcliffe WA, Eastell R, Bundred NJ. Measurement of urinary collagen cross-links indicate response to therapy in patients with breast cancer and bone metastases. Br J Cancer 1999, 80(8); 1265-1270. 88. Clark PJ, Eastell R, Barker ME. Zinc supplementation and bone growth in pubertal girls.Lancet 1999, vol 354:485. 89. Egan JJ, Maden C, Kalra S, Adams JE, Eastell R, Woodcock AA. A randomized, double-blind studycomparing the effects of beclomehtasone and fluticasone on bone density over two years. Eur Respir J 1999, vol 13:1267-1275. 90. Fatayerji D, Cooper AM, Eastell R. Total body and regional bone mineral density in men: Effect of age. Osteoporosis International 1999, 10:59-65. 91. Ferrar L, Eastell R. Identification of vertebral deformities in men: comparison of morphometric radiography and morphometric x-ray absorptiometry. Osteoporosis International 1999, vol 10:167-174. 92. Ingle BM, Hay SM, Bottjer HM, Eastell R. Changes in bone mass and bone turnover following distal forearm fracture. Osteoporosis International 1999, vol 10:399-407. 93. Ingle BM, Hay SM, Bottjer HM, Eastell R. Changes in bone mass and bone turnover following ankle fracture. Osteoporosis International 1999, vol 10:408-415. 94. Dennison E, Eastell R, Fall CHD, Kellingray S, Wood PJ, Cooper C. Determinants of 14 bone loss in elderly men and women: a prospective population-based study. Osteoporosis International 1999, vol 10:384-391. 95. Choy EH, Rankin EC, Kassimos D, Vetterlein O, Garyfallos A, Ravirajan CT, Sopwith M, Eastell R, Kingsley GH, Isenberg DA, Panayi GS. The engineered human antitumor necrosis factor-alpha antibody CDP571 inhibits inflammatory pathways but not patients with rheumatoid arthritis. J Rheumatol 1999, 26(11):2310-2317. 96. Spittlehoue AJ, Getty CJ, Eastell R. Measurement of bone mineral density by dualenergy x-ray absorptiometry around an uncemented knee prosthesis. J Arthroplasty 1999, vol 14, 8:957963. 97. Naylor KE, Iqbal P, Fledelius C, Fraser RB, Eastell R. The effect of pregnancy on bone density and bone turnover. J Bone Miner Res 2000, vol 15, 1:129-137. 98. Reginster J-Y, Minne HW, Sorensen OH, Hoooper M, Roux C, Brandi ML, Lund B, EthgenD, Pack S, Roumagnac I, Eastell R. Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. Osteoporosis International 2000, vol 11, 83-91. 99. Ferrar L, Jiang G, Barrington NA, Eastell R. Identification of vertebral deformities in women: comparison of radiological assessment and quantitative morphometry using morphometric radiography and morphometric x-ray absorptiometry. J Bone Miner Res 2000, vol 15, 3:575-585. 100. Eastell R, Mallinak N, Weiss S, Ettinger M, Pettinger M, Cain D, Flessland K. Chesnut III C. Biological variability of serum and urinary N-telopeptides of type I collagen in postmenopausal women. J Bone Miner Res 2000, vol 15, 3:594-598. 101.Harris NJ, Lowman A, Wolsey L, Hannon R, Smith TWD, Eastell R. Changes in bone turnover and bone density after total hip arthroplasty. Hip International 2000, vol 10; 1: 16-20. 102.Rogers A, Hannon RA, Eastell R. Biochemical markers as predictors of rates of bone loss after menopause. J Bone Miner Res 2000, vol 15, 7:1398-1404. 103 Eastell R, Devogelaer JP, Peel NFA, Chines AA, Bax DE, Sacco-Gibson N, Nagant de Deuxchaisnes C, Russell RGG. Prevention of bone loss with risedronate in glucocorticoid- treated rheumatoid arthritis patients. Osteoporosis International 2000, vol 11, 4:331-337. 104.Henry YM, Eastell R. Ethnic and gender differences in bone mineral density and bone turnover in young adults: Effect of bone size. Osteoporosis International 2000, vol 11, 512-517. 105.Fatayerji D, Mawer EB, Eastell R. The role of insulin-like growth factor I in agerelated changes in calcium homeostasis in men. J Clin Endo Metab 2000, vol 85, 12:4657-4662. 106.Falahati-Nini A, Riggs LB, Atkinson, EF, O'Fallon WM, Eastell R, Khosla S. Relative contributions of testosterone and estrogen in regulating bone resorption and formation 15 in normal elderly men. J Clin Invest. 2000, vol 106, 12;1553-1560. 107.Guo CY, Holland PA, Jackson BF, Hannon RA, Rogers A, Harrison BJ, Eastell R. Related articles, Links Immediate changes in biochemical markers of bone turnover and circulating interleukin-6 after parathyroidectomy for primary hyperparathyroidism. Euro J Endocrinol 2000, 142(5):451-9 108.McClung MR, Geusens P, Miller PD, Zippel H, Bensen WG, Roux C, Adami S, Fogelman I, Diamond T, Eastell R, Meunier PJ, Reginster JY. Effect of risedronate on the risk of hip fracture in elderly women. The New England Journal of Medicine 2001, vol 344: 5;333-340. 109. Zegels B, Eastell R, Russell RGG, Ethgen D, Roumagnac I, Collette J, Reginster JY. Effect of high doses of oral risedronate (20mg/day) on serum parathyroid hormone levels and urinary collagen cross-link excretion in postmenopausal women with spinal osteoporosis. Bone 2001, vol 28,1:108-112. 110.Quinton ND, Lee AJ, Ross RJM, Eastell R, Blakemore AIF. A single nucleotide polymorphism (SNP) in the leptin receptor is associated with BMI, fat mass and leptin levels in postmenopausal Caucasian women. Human Genetics 2001. 111.Gale CR, Martyn CN, Kellingray S, Eastell R, Cooper C. Intrauterine programming of adult body composition. J Clin Endo Metab 2001, 86:1;267-272. 112.Wilkinson JM, Stockley I, Peel NFA, Hamer AJ, Elson RA, Barrington NA, Eastell R. Effect of pamidronate in preventing local bone loss after total hip arthroplasty. A randomized, double-blind, controlled trial. JBMR 2001, 16:3;556-564. 113.Greenfield DM, Eastell R. Risk factors for ankle fracture. Osteoporosis International 2001, vol 12:2;97-103. 114.Ismail AA, Cockerill W, Cooper C, et al. Prevalent vertebral deformity predicts incident hip though not distal forearm fracture: results from the European Prospective Osteoporosis Study. Osteoporosis International 2001, vol 12, 85-90. 115.Ingle BM, Sherwood KE, Eastell R. Comparison of two methods for measuring ultrasound properties of the heel in postmenopausal women. Osteoporosis International 2001, vol 12:6;500505. 116.Wilkinson JM, Peel NFA, Elson RA, Stockley I, Eastell R. Measuring bone mineral density of the pelvis and proximal femur after total hip arthroplasty. J Bone & Joint Surgery (Br) 2001, vol 83:2;283-288. 117.Rogers A, Eastell R. The effect of 17-estradiol on production of cytokines in cultures in peripheral blood. Bone 2001, vol 29:1;30-34. 118.Ingle BM, Eastell R. Bone loss from the hand in women following distal forearm fracture. Osteoporosis International 2001, vol 12:7;610-615. 119.Ferrar L, Jiang G, Eastell R. Longitudinal evaluation of morphometric x-ray absorptiometry for the identification of vertebral deformities. Osteoporosis International 2001, vol 12:8;661-671. 16 120.Ferrar L, Jiang G, Eastell R. Short-term precision for morphometric x-ray absoprtiometry. Osteoporosis International 2001, vol 12:9;710-715. 121.Ferrar L, Jiang G, Eastell R. Vertebral wedge angle measured by morphometric x-ray absorptiometry. Osteoporosis International 2001, vol 12:914-921. 122. Price JS, Jackson BF, Gray JA, Harris PA, Wright IM, Pfeiffer DU, Robins SP, Eastell R, Ricketts SW. Biochemical markers of bone metabolism in growing thoroughbreds: a longitudinal study. Res Vet Sci 2001, vol 71:1;37-44. 123. Newton D, Ancill AK, Naylor KE, Eastell R. Long-term retention of injected barium-133 in man. Radiation Protection Dosimetry, vol 97, 3:231-240. 124.Ingle BM, Eastell R. Site-specific bone measurements in patients with ankle fracture. Osteoporosis International 2002, vol 13:4:342-347. 125.Clowes JA, Hannon RA, Yap TS, Hoyle NR, Blumsohn A, Eastell R. Effect of feeding on bone turnover markers and its impact on biological variability of measurements. Bone 2002, vol 30, 6:886-890. 126.Ingle BM, Thomas WEG, Eastell R. Differential effects of primary hyperparathyroidism on ultrasound properties of bone. Osteoporosis International 2002, vol 13, 7:572-578. 127.Clowes JA, Robinson RT, Heller SR, Eastell R, Blumsohn A. Acute changes of bone turnover and PTH induced by insulin and glucose: euglycemic and hypoglycaemic hyperinsulinemic clamp studies. J Clin Endo & Metab 2002, vol 87, 7:3324-3329. 128.Kilding R, Eastell R, Peel N. Do patients receive appropriate information and treatment following bone mineral density measurements? Rheumatology (Letter) 2002; 41:10731074. 129.Wilkinson JM, Hamer AJ, Elson RA, Stockley I, Eastell. Precision of EBRA-Digital software for monitoring implant migration after total hip arthroplasty. J Arthroplasty 2002 17:910-6. 130.Rogers A, Saleh G, Hannon RA, Greenfield D, Eastell R. Circulating estradiol and osteoprotegerin as determinants of bone turnover and bone density in postmenopausal women. J Clin Endocrinol Metab 2002; 87:4470-5. 131. Pereda CA, Hannon RA, Naylor KE, Eastell R. The impact of subcutaneous implants on biochemical markers of bone turnover and bone mineral density in postmenopausal women. Brit J Obstet Gynaecol 2002; 109:812-20. 132.Findlay SC, Eastell R, Ingle BM. Measurement of bone adjacent to tibial shaft fracture. Osteoporosis International 2002. vol 13, 12:980-989. 133.Felsenberg D, Silman AJ, Lunt M, …. Eastell R,……et al. Incidence of vertebral fracture in Europe: Results from the European Prospective Osteoporosis Study (EPOS). J Bone Min Res 2002, vol 17, 4:716-274 17 134.Delmas PD, Ensrud KE, Adachi JD, .... Eastell R. Efficacy of raloxifene on vertebral fracture risk reduction in postmenopausal women with osteoporosis: four-year results from a randomized clinical trial. J Clin Endocrinol Metab 2002, 87;8:3609-17 135.Roy DK, O’Neill TW, Finn JD,…. Eastell R, … et al. Determinants of incident vertebral fracture in men and women: results from the European Prospective Osteoporosis Study (EPOS). Osteoporosis International 2003, vol 14, 1:19-26. 136.Naylor KE, Jackson B, Eastell R. Renal clearance of free and peptide-bound deoxypyridinoline: response to pamidronate treatment of Paget’s disease. JBMR J Bone Min Res 2003, vol 18:4;658-661 137. Leder BZ, LeBlanc KM, Schoenfeld DA, Eastell R, Finkelstein JS. Differential effects of androgens and estrogens on bone turnover in normal men. J Clin Endo Metab 2003, vol 88:1;204-210 138. Wilkinson JM, Stockley I, Hamer AJ, Barrington NA, Eastell R. Biochemical markers of bone turnover and development of heterotopic ossification after total hip arthroplasty. J Orthop Res 2003, 21:3;529-534 139. Ferrar L, Jiang G, Eastell R, Peel NFA. Visual identification of vertebral fractures in osteoporosis using morphometric x-ray absorptiometry. J Bone Min Res 2003, vol 18:5;933-938 140. Eastell R, Barton I, Hannon RA, Chines A, Garnero P, Delmas PD. Relationship of early changes in bone resorption to the reduction in fracture risk with risedronate. J Bone Min Res 2003, vol 18:6;1051-1056 141. Wilkinson JM, Hamer AJ, Rogers A, Stockley I, Eastell R. Bone mineral density and biochemical markers of bone turnover in aseptic loosening after total hip arthroplasty. J Orthop Res 2003, 21:691-696 142. Cooper MS, Blumsohn A, Goddard PE, Bartlett WA, Shackleton CH, Eastell R, Hewison M, Stewart PM. 11-hydroxysteroid dehydrogenase type I activity predicts the effects of glucocorticoids on bone. J Clin Endo & Metab 2003, vol 88:8;3874-3877 143. Reeve J, Lunt M, Felsenberg D, Silman AJ,….. Eastell R,….. et al. Determinants of the size of incident vertebral deformities in European men and women in the sixth to ninth decades of age: The European Prospective Osteoporosis Study (EPOS). J Bone Min Res 2003, vol 18,:9;1664-1673 144. Blumsohn A, Naylor KE, Timm W, Eagleton AC, Hannon RA, Eastell R. Absence of marked seasonal change in bone turnover: a longitudinal and multicenter crosssectional study. J Bone Min Res 2003, vol 18:7;1274-1281 145. Wilkinson JM, Wilson AG, Stockley I, Scott IR, Macdonald DA, Hamer AJ, Duff GW, Eastell R. Variation in the TNF gene promoter and risk of osteolysis after total hip arthroplasty. J Bone Miner Res 2003, vol 18:11;1995-2001 146. Clowes JA, Allen HC, Prentis DM, Eastell R, Blumsohn A. Octreotide abolishes the acute decrease in bone turnover in response to oral glucose. J Clin Endo & Metab 2003, vol 88:10;4867-4873 18 147. Naylor KE, Rogers A, Fraser RB, Hall V, Eastell R, Blumsohn A. Serum osteoprotegerin as a determinant of bone metabolism in a longitudinal study of human pregnancy and lactation. J Clin Endo & Metab 2003, vol 88:11;5361-5365 148. Wilkinson JM, Jackson B, Eastell R. Effect of pamidronate on excretion of pyridinium crosslinks of collagen after total hip arthroplasty. Calcified Tissue International 2003, vol 73:4;326-331 149. Jackson BF, Goodship AE, Eastell R, Price JS. Evaluation of serum concentrations of biochemical markers of bone metabolism and insulin-like growth factor I associated with treadmill exercise in young horses. Am J Vet Res 2003, 64:12;1549-56 150. Hannon RA, Clowes JA, Eagleton AC, Al Hadari A, Eastell R, Blumsohn A. Clinical performance of immunoreactive tartrate-resistant acid phosphate isoform 5b as a marker of bone resorption. Bone 2004, vol 34:1;187-194 151. Cockerill W, Lunt M, Silman AJ, Cooper C,…… Eastell R,….. et al. Health-related quality of life and radiographic vertebral fracture. Osteoporosis International 2004, vol 15:2;113-119 152. Clowes JA, Peel NFA, Eastell R. The impact of monitoring on adherence and persistence with antiresorptive treatment for postmenopausal osteoporosis: A randomised controlled trial. J Clin Endo & Metab 2004, vol 89:3;1117-1123 153. Henry YM, Fatayerji D, Eastell R. Attainment of peak bone mass at the lumbar spine, femoral neck and radius in men and women: relative contributions of bone size and volumetric bone mineral density. Osteoporosis International 2004, vol 15:4;263-273 154. Gluer CC, Eastell R, Reid DM, ….. Kolta S. Association of five quantitative ultrasound devices and bone densitometry with osteoporotic vertebral fractures in a population-based sample: The OPUS study. J Bone Min Res 2004, vol 19;5:782-793 155. Roux C, Seeman E, Eastell R, Adachi J, et al. Efficacy of risedronate on clinical vertebral fractures within six months. Curr Med Res Opin 2004, 20:4;433-439 156. Reid IR, Eastell R, Fogelman I, Adachi JD, et al. A comparison of the effects of raloxifene and conjugated equine estrogen on bone and lipids in healthy postmenopausal women. Arch Intern Med 2004, 164:8;871-9 157. Watts NB, Cooper C, Lindsay R, Eastell R, Manhart MD, Barton IP,k van Staa TP, Adachi JD. Relationship between changes in bone mineral density and vertebral fracture risk associated with risedronate: Greater increases in bone mineral density do not relate to greater decreases in fracture risk. J Clin Densitometry 2004, vol 7;3: 255-261 158. Jiang G, Eastell R, Barrington NA, Ferrar L. Comparison of methods for the visual identification of prevalent vertebral fracture in osteoporosis. Osteoporosis International 2004, vol 15:887-896 159. Boonen S, McClung MR, Eastell R, El-Hajj Fuleihan G, Barton IP, Delmas P. Safety and efficacy of risedronate in reducing fracture risk in osteoporotic women aged 80 19 and older: Implications for the use of antiresorptive agents in the old and oldest old. J Am Geriatr Soc 2004, vol 52:1832-1839 160. Veitch SW, Findlay SC, Ingle BM, Ibbotson CJ, Barrington A, Hamer AK, Eastell R. Accuracy and precision of peripheral quantitative computed tomography measurements at the tibial metaphysic. J Clin Densitometry 2004, vol 7:2;209-217 161. Wilkinson JM, Eagleton AC, Stockley I, Peel NFA, Hamer AJ, Eastell R. Effect of pamidronate on bone turnover and implant migration after total hip arthroplasty: a randomised trial. J Ortho Research 2005:23;1-8 162. Gluer CC, Eastell R, Reid DM……Kolta S. Reply – Risk assessment and fracture discrimination by ultrasound: the debate continues. J Bone Min Res 2005, vol 20 : 3 ; 539-540 163. Siminoski K, Jiang G, Adachi JD…….Eastell R. Accuracy of height loss during prospective monitoring for detection of incident vertebral fractures. Osteo Int 2005, vol 16:403-410 164. Delmas P, van de Langerijt L, Watts NB, Eastell R, ….. Cahall D for the IMPACT Study Group. Underdiagnosis of vertebral fractures is a worldwide problem: The IMPACT Study. J Bone Min Res 2005, vol 20:4,557-563 165. Wilkinson JM, Hamer AJ, Stockley I, Eastell R. Polyethylene wear rate and osteolysis: critical threshold versus continuous dose-response relationship. J Ortho Research 2005:23;520-525 166. Ingle BM, Machado AB, Pereda CA, Eastell R. Monitoring alendronate therapy with quantitative ultrasound and bone mineral density. J Clin Densitometry 2005, vol 8:3:278-286 167. Siris ES, Harris ST, Eastell R, Zanchetta JR……Cummings SR for the Continuing Outcomes Relevant to Evista (CORE) Study. Skeletal effects of raloxifene after 8 years: Results from the Continuing Outcomes Relevant to Evista (CORE) Study. J Bone Miner Res 2005, vol 20:9;1514-1524 168. Lemos MC, Kotanko P, Christie PT, Harding B, Javor T, Smith C, Eastell R, Thakker RV. A novel EXT1 splice site mutation in a kindred with hereditary Multiple exostosis and osteoporosis. J Clin Endo Metab 2005, vol 90(9):5386-5392 169. Clowes JA, Eastell R, Peel NF. The discriminative ability of peripheral and axial bone measurements to identify proximal femoral, vertebral, distal forearm and proximal humeral fractures: A case control study Osteo Int 2005, vol 16:12; 1794-1802 170. Paggiosi MA, Blumsohn A, Barkmann R, Eastell R. Effect of temperature on the Longitudinal variability of quantitative ultrasound variables. J Clin Densitometry 2005, vol 8:4;436-444 171. Eastell R, Krege JH, Chen P, Glass EV, Reginster JY. Development of an algorithm for using P1NP to monitor treatment of patients with teriparatide. Current Medical Research and Opinions 2006, vol 22:1;61-66 20 172. Merza Z, Blumsohn A, Mah PM, Meads DM, McKenna SP, Wylie K, Eastell R, Wu F. Double-blind placebo-controlled study of testosterone patch therapy on bone turnover in men with borderline hypogonadism. Int J Androl 2006, 381-391 173. Veitch SW, Findlay SC, Hamer AJ, Blumsohn A, Eastell R, Ingle BM. Changes in bone mass and bone turnover following tibial shaft fracture. Osteo Int 2006, vol 17:364-372 174. Shetty NR, Hamer AJ, Kerry RM, Stockley I, Eastell R, Wilkinson JM. Bone remodeling around a cemented polyethylene cup. J Bone & Joint Surgery 2006, vol 88:4;455-459 175. Smith CM, Coombs RC, Gibson AT, Eastell R. Adaptation of the Carter method to adjust lumbar spine bone mineral content for age and body size: application to children who were born preterm. J Clin Densitometry 2006, vol 9:1;114-119 176. Melton LJ III, Wenger DE, Atkinson EJ, Achenback SJ, Berquist TH, Riggs BL, Jiang G, Eastell R, Influence of baseline deformity definition on subsequent vertebral fracture risk in postmenopausl women. Osteo Int 2006, vol 17:978985 177. Eastell R, Hannon RA, Cuzick J, Dowsett M, Clack, G, Adams JE, on behalf of the ATAC Trialists Group. Effect of an aromatase inhibitor on BMD and bone turnover markers: 2-year results of the Anastrozole, Tamoxifen, Alone or in Combination (ATAC) Trial (18233230). J Bone Miner Res 2006, vol 21:8; 1215-1223 178. Clowes JA, Peel NFA, Eastell R. Device-specific thresholds to diagnose osteoporosis at the proximal femur: an approach to interpreting peripheral bone measurements in clinical practice. Osteo Int 2006, vol 17:9;1293-1302 179. Kaptoge S, Armbrecht G, Felsenber D………Eastell R…..Reeve J. Whom to treat? The contribution of vertebral x-rays to risk-based algorithms for fracture prediction. Results from the European Prospective Osteoporosis Study. Osteo Int 2006, vol 17: 9;1369-1381 180. Stewart A, Felsenber D, Eastell R, Roux C, Gluer CC, Reid DM. Relationship between risk factors and QUS in a European Population: The OPUS study. Bone 2006, vol 39:609-615 181. Ali AM, Saleh M, Eastell R, Wigderowitz CA, Rigby AS, Yang L. Influence of bone quality on the strength of internal and external fixation of tibial plateau fractures. J Ortho Res 2006, 2080-2086 182. Shetty N, Hamer AJ, Stockley I, Eastell R, Wilkinson JM. Clinical and radiological outcome of total hip replacement five years after pamidronate therapy. A trial extension. J Bone Joint Surg 2006, vol 88:10;1309-15 183. Shetty N, Hamer AJ, Stockley I, Eastell R, Wilkinson JM. Precision of periprosthetic bone mineral density measurements using Holgic Windows versus DOS-based analysis 21 software. J Clin Densitom 2006, vol 9:3;363-6 184. Rogers A. Clowes JA, Pereda CA, Eastell R. Different effects of raloxifene and estrogen on interleukin-1β and interleukin-1 receptor antagonist production using in vitro and ex vivo studies. Bone 2007, vol 40:1;105-110 185. Kaptoge S, Reid DM, Scheidt-Nave C, ……Eastell R, …….Reeve J. Geographic and other determinants of BMD change in European men and women at the hip and spine. A population based study from the Network in Europe for Male Osteoporosis (NEMO). Bone 2007, vol 40:662-673 186. Black DM, Delmas PD, Eastell R,… ..Cummings SR. Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. The New England Journal of Medicine, 2007, vol 356;18:1809-1822 22