“Irritable bowel syndrome: hypothesis of osteopathic treatment " Abstract: IBS or irritable bowel syndrome as defined by American authors, is a colon functional disorder that can lead to the onset of clinical syndrome quite frequently. The etiology is certainly complex, but in most cases it is believed, to have psychosomatic origins while the importance of other factors cannot be excluded. Very often, patients with irritable bowel syndrome have a particular personality defined “obsessive-compulsive disorder”: mostly. These ordered, punctual, conscientious, precise, methodical subjects live in a rather obsessive condition and under a conflicting situation where aggressive instincts are constantly repressed. Until recently, the clinical strategy and the therapeutic approach were almost exclusively based upon the information derived from anatomical imaging and administration of drugs to improve bowel functionality. Scope of the study: to determine the effectiveness of osteopathic treatment in major gastrointestinal diseases such as irritable bowel syndrome, which can then be taken into account by the osteopathic medicine, especially in those patients who did not achieve a satisfactory result only with the drug therapy which may cause unfavorable side effects in a long run. Method: in collaboration with a gastroenterologist in Savona, we conducted a study on 20 patients diagnosed with irritable bowel syndrome; some of them presented associated muscullskeletal symptoms such as back pain, sciatica, lowel limbs pain and one had right shoulder pain. The osteopathic protocol was amended each time according to the osteopathic fixations identified in each single patient; number of sessions: 1 every 3 weeks for 3 times followed by 1 every 4 weeks for 2 times. Results: The therapeutic response was positive only in 12 patients with improvement of abdominal pain,decreased bloating feeling or abdominal distension, improvement in the rate of bowel movement and improvement of intestinal disorders. The associated bone and joint disorders disappeared in all patients. As for the 8 patients who did not achieve positive results through our osteopathic protocol, we believe that the reason relates to the strong psychosomatic aspect that we did not take into consideration. Conclusions: the osteopath preparation is very serious but in order to officially acknowledge the Oateopathy, it is essential to value the scientific research and sustain objectively the obtained results with numerical data. The overall osteopathic approach does not treat the symptoms only, but looks for the primary cause of the problem, often gets to results that the traditional rehabilitation therapy is not reaching, and particularly is not maintaining stable over the time. This study allowed us to compare the values registered before and after the treatment, in order to confirm the hypothesis formulated during the initial clinical and osteopathic evaluation, also allowing us to objectively quantify the positive outcomes in term of numbers and to implement a selection of patients suitable for undergoing a “visceral” type of osteopathic treatment rather than a “somato-emotional” one. Keywords: IBS, Roma criteria, placebo, osteopathic tests, visceral manipulation.