CMRC IRB MAXIMUM ALLOWABLE TOTAL BLOOD DRAW VOLUMES (CLINICAL + RESEARCH) Body Wt (Kg) Body Wt (lbs) Total blood volume (mL) Maximum allowable volume (mL) in one blood draw ( = 2.5% of total blood volume) Total volume (clinical + research) maximum volume (mL) drawn in a 30day period 1 2 3 4 5 6 7 8 9 10 11-15 16-20 21-25 26-30 31-35 36-40 41-45 46-50 51-55 56-60 61-65 68-70 71-75 76-80 81-85 86-90 91-95 96-100 2.2 4.4 6.3 8.8 11 13.2 15.4 17.6 19.8 22 24-33 35-44 46-55 57-66 68-77 79-88 90-99 101-110 112-121 123-132 134-143 145-154 156-185 167-176 178-187 189-198 200-209 211-220 100 200 240 320 400 480 560 640 720 800 880-1200 1280-1600 1680-2000 2080-2400 2480-2800 2880-3200 3280-3600 3680-4000 4080-4400 4480-4800 4880-5200 5280-5600 5680-6000 6080-6400 6480-6800 6880-7200 7280-7600 7680-8000 2.5 5 6 8 10 12 14 16 18 20 22-30 32-40 42-50 52-60 62-70 72-80 82-90 92-100 102-110 112-120 122-130 132-140 142-150 152-160 162-170 172-180 182-190 192-200 5 10 12 16 20 24 28 32 36 40 44-60 64-80 64-100 104-120 124-140 144-160 164-180 184-200 204-220 224-240 244-260 264-280 284-300 304-360 324-340 344-360 364-380 384-400 kg 1-2 >2 Based on blood volume of: mL/kg 100 80 Minimum Hgb required at time of blood draw 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 Minimum Hgb required at time of blood draw if subject has respiratory/CV compromise 9.0 -10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 9.0-10.0 Pre-term infant Term infant - adult This information is similar to that used by the Committee on Clinical Investigations, Children’s Hospital in Los Angeles, CA; Baylor College of Medicine, Dallas, TX; and Cincinnati Children’s Hospital Institutional Review Board, OH. These charts were adapted by: Rhona Jack, Ph.D. Children’s Hospital and Regional Medical Center Laboratory, Seattle, WA in August 2001. Approved by CMRC IRB on 9/18/06