Jordan University of Science and Technology Section of Anaesthesiology COURSE NAME : COURSE NUMBER: Credit hours : YEAR 5 Anaesthesia MED 554 2.25/ 2 WEEKS M554 Anesthesia (2.25 credit hours, 2 weeks) This 2-week course is offered to the fifth year medical students. During this clinical rotation students will spend their morning hours in the operating theater learning basic principles of anesthesia including airway management, fluid management, induction and maintenance of anesthesia, patient’s monitoring, and recovery. Students will be given daily seminars that cover important aspects of anesthesia. General objectives Please add general objcetives 1. Airway management skills 2. Mask ventilation and tracheal intubation, 3. securing intravenous access 4. Preoperative assessment of the Airways. 5. The appropriate use of local anaesthetic Agents Program of teaching undergraduate fifth year medical students during the rotation in Anaesthesia and operating theatres. Specific objectives Observation of induction of Anaesthesia Observation of Endotracheal Intubation Observation and monitoring recovery from General Anaesthesia 8. Observation of Local and Regional Blocks Skills to be learned 1. 2. 3. 4. 5. 6. 7. Intravenous cannulation Setting up intravenous infusion Connecting monitoring devices Maintenance of the Airway in unconscious patient 5011509970 خـالـد الـردايـدة.د منسق المساق رئيس قسم التخدير وأإلنعاش 1 I. Anaesthetic Agents (Intravenous Anaesthetic ) 1.1. Barbiturate: (Thiopentone) Thiopentone Ketamine ● physical, chemical properties and presentation ● Pharmacokinetics ● Pharmadynamics (effect on the different organ systems) ● Dosage and Administration ● Indications and Contraindications(absolute and relative) ● Adverse effects (extravascular,intraarterial,Allergy.........) ● physical, chemical properties and presentation ● Pharmacokinetics and mechanism of action ● Pharmadynamics (effect on the different organ systems) ● Dosage and Administration ● Indications and Contraindications Other adJuvant intravenous anaesthetic agents: ● Benzodiazepines (only midazolam and Diazepam) ● Narcotic Agonists and Antagonists : Definition, Site of action, Effect on organ systems, Fentanyl and Morphine. ● Narcotic Antagonist :Naloxone. 1.2.Non- Barbiturate: (Propofol, Ketamine) Prpopfol ● physical, chemical properties and presentation ● Pharmadynamics (effect on the different organ systems) ● Dosage and Administration ● Indications and Contraindications II. Anaesthetic Agents (Inhalational Agents) ● MAC and factors which alter MAC. Nitrous Oxide(N2O): ● Factors determining how quickly the inhalational agent reaches the alveoli ● Factors determining how quickly the inhalational agent reaches the brain from the alveoli in order to establish anaesthesia ● MAC Value of N2O, Halothane, Isoflurane, Sevoflurane ● physical properties ● MAC Value of N2O ● The second gas effect ● Diffusion hypoxia ● Effect on closed gas spaces Halothane, Isoflurane, Sevoflurane ● IN DETAILS ●Enlurane. And Deslurane JUST the value of MAC III. Muscle relaxant& Anticholinergic drugs& Cholinesterase inhibitors 1.Physiology of neuromuscular Transmission 2.Depolarizing Muscle relaxant: ● Suxamethonium: * Structure and Mechanism of action * Dose onset and duration of action * Indications and Contraindications * Side effects of Suxamethonium * Factor Affecting duration of Suxamethonium 4. Anticholinergic drugs:(mainlyAtropine) * Effect on the different organ systems: (Cardiovascular, Salivary Glands, smooth muscles and Pupils) * Dose. * (Scopolamine and Glycopyrrolate: differences to Atropine) 3. Non-Depolarizing Muscle relaxant: 5. Cholinesterase inhibitors: (mainly Neostigmin) * Mechanism of action * Factor Affecting duration of Non-Depolarizing Muscle relaxant ● Atracurium and Cis-Atracurium (Tracrium®): in Dtails ● Rocuronium bromide (Esmeron®): in Details ● Pancuronium bromide (Pavulon®): in Details ● Vecuronium bromide (Norcuron®): in Details * Mechanism of action * effect on the different organ systems: (Cardiovascular, Salivary Glands, smooth muscles and Pupils) * Dose. 6. The role of Anticholinergic drugs(Atropin) and Anti Cholinesterase (Neostigmine) in the Anesthesia? ● JUST MENTION BY NAME: * Mivacurium * Alcuronium * Tubocurarine 5011509970 خـالـد الـردايـدة.د منسق المساق رئيس قسم التخدير وأإلنعاش 2 4. Anaesthesia for tracheal intubation: IV. Conduct of Anesthesia 4.1. Inhalational technique for intubation 4.2. Relaxant Anaesthesia * Indications 5. Conduct of extubation: * Procedure * Complications of tracheal extubation 1. Inhalational Induction: * Procedure *Indications *Difficulties and Complications 2. Maintenance of Anaesthesia 2.1. Conduct of inhalational Anaesthesia with spontaneous ventilation 2.2. Difficulties and complications 3. 2.Airway Maintenance delivery of inhalational agents * face mask * Laryngeal mask * Tracheal intubation (Indications) 5. Laryngoscopes and type of blades V. Intubation and Anatomy of the Airway And Anesthesia apparatus 1. 2. 3. 4. Assessment of patients airway including 1-2-3-Test Different classifications of airway structures The technique of tracheal intubation ( the 5 steps in Detail) The anatomical structures seen in region of intubation (name of these structures) 6. Tracheal tubes: size and types of tubes 7. Shape of tube and specialized tubes 8. the laryngeal mask 9. Other apparatus including oro- and nasopharyngeal airways. VI.Monitoring in Anesthesia 1. Anesthsia Depth 2. Guidelines to the practice of anaesthesia and patient Monitoring 3. What and how we monitor the Oxygenation, ventilation, \circulation, Tempreture 5. how to identify Cynosis 6. O2- Hb-dissociation curve 7. the normal values of monitored parameters for a healthy adult 4. Moniting : ECG, Pulsoximertry, Blood pressure , CVP, Capnography EtCO2 Undergoing general anesthesia VII. Local Anaesthetic Agents VIII. Local Anaesthetic Techniques The Pharmacology of Local Anaesthetic Agents 1.Definition 2. Classification of Local Anaesthetic Agents 2.1. Comparison between the two Classes. 3. Mode of action 4. Preparation of Local Anaesthetic Agents 5. Addition of Vasoconstrictors 5.1. Indications and Contraindications and Dosage. 5.2. How can I prepare Adrenaline 1:200000? 6. Clinical uses of local anesthetic agents 7. Lidocaine 8.Toxicity (Causes, Prevention and Treatment) 8.1. Systemic Toxicity 1. Central Block: Spinal and Epidural Anaesthesia 1.1. Procedure including Anatomy, 1.2. Indications and contraindications 1.3. Complications (Prevention and Treatment) 2. I.V.R.A. (BIER S Block) 1.1. Procedure 1.2. Indications and contraindications 1.3.Complications (Prevention and Treatment) Please add typical teaching activities during the rotation on weekly basis Please add the name of references and text books including name of the of the book 5011509970 خـالـد الـردايـدة.د منسق المساق رئيس قسم التخدير وأإلنعاش 3