A/CANCER DE PULMON NO CELULA PEQUEÑA (CPNCP)
A.5. RADIOTERAPIA
A.5.1. RADIOTERAPIA RADICAL
- Branislav Jeremic, Johannes Classen, Michael Bamberg. Radiotherapy alone in technically
operable, medically inoperable, early-stage (I/II) non-small-cell lung cancer
International Journal of Radiation Oncology * Biology * Physics Vol. 54, Issue 1, Pages 119-130
- Rowell NP, Williams CJ. Radical radiotherapy for stage I/II non-small cell lung cancer in
patients not sufficiently fit for or declining surgery (medically inoperable). Cochrane
Database Syst Rev 2001.
A.5.2. RADIOTERAPIA PALIATIVA
- Falk SJ, Girling DJ, White RJ, et al. Immediate versus delayed palliative thoracic
radiotherapy in patients with unresectable locally advanced non-small cell lung cancer
and minimal thoracic symptoms: randomised controlled trial. BMJ 2002; 325:465.
A.5.3. RADIOTERAPIA POSTOPERATORIA
- PORT Meta-analysis Trialists Group: Post-operative radiotherapy in non-small cell lung
cancer: Systematic review and meta-analysis of individual patient data from nine
randomised controlled trials. Lancet 352:257-263, 1998.
- Burdett S, Stewart L: Postoperative radiotherapy in non small cell lung cancer: Up date
of an individual patient data meta-analysis. Lung Cancer 47:81-83, 2005.
- Machtay M, Lee JH, Shrager JB, et al: Risk of death from intercurrent disease is not
excessively increased by modern postoperative radiotherapy for high-risk resected nonsmall-cell lung carcinoma. J Clin Oncol 19:3912-3917, 2001
- Lally BE, Zelterman D, Colasanto JM, Haffty BG, Detterbeck FC, Wilson LD. Postoperative
radiotherapy for stage II or III non-small-cell lung cancer using the surveillance,
epidemiology, and end results database. J Clin Oncol 24:2998–3006, 2006.
- Keller SM, Adak S, Wagner H, et al: A randomized trial of post-operative adjuvant therapy
in patients with completely resected stage II or III-A non-small cell lung cancer:
Eastern Cooperative Oncology Group. N Engl J Med 343:1217-1222, 2000.
- Bonner JA, Spencer SA: Postoperative radiotherapy in non-small-cell lung cancer
warrants further exploration in the era of adjuvant chemotherapy and conformal
radiotherapy. J Clin Oncol 24:2978-2980, 2006.
- Douillard JY, Rosell R, De Lena M, Riggi M, Hurteloup P, Mahe MA; Adjuvant Navelbine
International Trialist Association. Impact of postoperative radiation therapy on survival
in patients with complete resection and stage I, II, or IIIA non-small-cell lung cancer
treated with adjuvant chemotherapy: the adjuvant Navelbine International Trialist
Association (ANITA) Randomized Trial. Int J Radiat Oncol Biol Phys. 72:695-701, 2008
A.5.4. SBRT
- Potters L, Kavanagh B, Galvin JM, et al. American Society for Therapeutic Radiology and
Oncology (ASTRO) and American College of Radiology (ACR) practice guideline for the
performance of stereotactic body radiation therapy. Int J Radiat Oncol Biol Phys 2010;
76:326.
- Timmerman R, Paulus R, Galvin J, et al. Stereotactic body radiation therapy for inoperable
early stage lung cancer. JAMA 2010; 303:1070.
- Palma D, Visser O, Lagerwaard FJ, et al. Impact of introducing stereotactic lung
radiotherapy for elderly patients with stage I non-small-cell lung cancer: a populationbased time-trend analysis. J Clin Oncol 2010; 28:5153.
- Alexander V. Louie, George Rodrigues, Malek Hannouf, Gregory S. Zaric, et al. Stereotactic
Body Radiotherapy Versus Surgery for Medically Operable Stage I Non–Small-Cell Lung
Cancer: A Markov Model–Based Decision Analysis. International Journal of Radiation
Oncology * Biology * Physics Vol. 81, Issue 4, Pages 964-973
- Mark K. Buyyounouski, Peter Balter, Brett Lewis, David J. D'Ambrosio, et al. Stereotactic Body
Radiotherapy for Early-Stage Non-Small-Cell Lung Cancer: Report of the ASTRO
Emerging Technology Committee. International Journal of Radiation Oncology * Biology *
Physics Vol. 78, Issue 1, Pages 3-10
- David Palma, Frank Lagerwaard, George Rodrigues, Cornelis Haasbeek, et al.Curative
Treatment of Stage I Non-Small-Cell Lung Cancer in Patients With Severe COPD:
Stereotactic Radiotherapy Outcomes and Systematic Review. International Journal of
Radiation Oncology * Biology * Physics Vol. 82, Issue 3, Pages 1149-1156
- Hiroshi Onishi, Hiroki Shirato, Yasushi Nagata, Masahiro Hiraoka, et al. Stereotactic Body
Radiotherapy (SBRT) for Operable Stage I Non–Small-Cell Lung Cancer: Can SBRT Be
Comparable to Surgery. International Journal of Radiation Oncology * Biology * Physics Vol. 81,
Issue 5, Pages 1352-1358
- Patrick Kelly, Peter A. Balter, Neal Rebueno, Hadley J. Sharp, et al. Stereotactic Body
Radiation Therapy for Patients With Lung Cancer Previously Treated With Thoracic
Radiation. International Journal of Radiation Oncology * Biology * Physics Vol. 78, Issue 5, Pages
1387-1393
- Alexander Chi, Zhongxing Liao, Nam P. Nguyen, Jiahong Xu, et al. Systemic review of the
patterns of failure following stereotactic body radiation therapy in early-stage nonsmall-cell lung cancer: Clinical implications. Radiotherapy and Oncology Vol. 94, Issue 1,
Pages 1-11
A.5.5. HIPERFRACCIONAMIENTO
- Saunders M, Dische S, Barrett A, et al. Continuous, hyperfractionated, accelerated
radiotherapy (CHART) versus conventional radiotherapy in non-small cell lung cancer:
mature data from the randomised multicentre trial. CHART Steering committee.
Radiother Oncol 1999; 52:137.
- Branislav Jeremić, Biljana Miličić, Slobodan Milisavljevic. Concurrent Hyperfractionated
Radiation Therapy and Chemotherapy in Locally Advanced (Stage III) Non-Small-Cell
Lung Cancer: Single Institution Experience With 600 Patients. International Journal of
Radiation Oncology * Biology * Physics Vol. 82, Issue 3, Pages 1157-1163
- Matthew Hatton, Matthew Nankivell, Ethan Lyn, Stephen Falk, et al. Induction Chemotherapy
and Continuous Hyperfractionated Accelerated Radiotherapy (CHART) for Patients With
Locally Advanced Inoperable Non–Small-Cell Lung Cancer: The MRC INCH Randomized
Trial .International Journal of Radiation Oncology * Biology * Physics Vol. 81, Issue 3, Pages 712718
- M. Baumann, T. Herrmann, R. Koch, W. Matthiessen, et al. Final results of the randomized
phase III CHARTWEL-trial (ARO 97-1) comparing hyperfractionated-accelerated versus
conventionally fractionated radiotherapy in non-small cell Lung Cancer (NSCLC).
Radiotherapy and Oncology Vol. 100, Issue 1, Pages 76-85
- Jeremić B, Milicić B. From conventionally fractionated radiation therapy to
hyperfractionated radiation therapy alone and with concurrent chemotherapy in
patients with early-stage nonsmall cell lung cancer. Cancer 2008; 112:876.
A.5.6. Irradiación profiláctica craneal
- Aupérin A., Arriagada R., Pignon J.-P., et al.Prophylactic Cranial Irradiation for Patients
with Small-Cell Lung Cancer in Complete Remission.N Engl J Med 1999; 341:476 – 484
- Slotman B., Faivre-Finn C., Kramer G., et al. Prophylactic Cranial Irradiation in Extensive
Small-Cell Lung Cancer. N Engl J Med 2007; 357:664 – 672
- Aaron H. Wolfson, Kyounghwa Bae, Ritsuko Komaki, Christina Meyers, et al. Primary Analysis of
a Phase II Randomized Trial Radiation Therapy Oncology Group (RTOG) 0212: Impact
of Different Total Doses and Schedules of Prophylactic Cranial Irradiation on Chronic
Neurotoxicity and Quality of Life for Patients With Limited-Disease Small-Cell Lung
Cancer .International Journal of Radiation Oncology * Biology * Physics Vol. 81, Issue 1, Pages 7784
- Le Péchoux C, Dunant A, Senan S, et al. Standard-dose versus higher-dose prophylactic
cranial irradiation (PCI) in patients with limited-stage small-cell lung cancer in
complete remission after chemotherapy and thoracic radiotherapy (PCI 99-01, EORTC
22003-08004, RTOG 0212, and IFCT 99-01): a randomised clinical trial. Lancet Oncol
2009; 10:467.
- Meert AP, Paesmans M, Berghmans T, et al. Prophylactic cranial irradiation in small cell
lung cancer: a systematic review of the literature with meta-analysis. BMC Cancer 2001;
1:5.
- Lester JF, MacBeth FR, Coles B. Prophylactic cranial irradiation for preventing brain
metastases in patients undergoing radical treatment for non-small-cell lung cancer: a
Cochrane Review. Int J Radiat Oncol Biol Phys 2005; 63:690.
- Gore EM, Bae K, Wong SJ, et al. Phase III comparison of prophylactic cranial irradiation
versus observation in patients with locally advanced non-small-cell lung cancer:
primary analysis of radiation therapy oncology group study RTOG 0214. J Clin Oncol 2011;
29:272.
- Sun A, Bae K, Gore EM, et al. Phase III trial of prophylactic cranial irradiation compared
with observation in patients with locally advanced non-small-cell lung cancer:
neurocognitive and quality-of-life analysis. J Clin Oncol 2011; 29:279.
A.5.7. IRRADIACION NODAL
- José S.A. Belderbos, Lucyna Kepka, Feng-Ming (Spring) Kong, Mary K. Martel, et al. Report From
the International Atomic Energy Agency (IAEA) Consultants' Meeting on Elective Nodal
Irradiation in Lung Cancer : Non–Small-Cell Lung Cancer (NSCLC). International Journal of
Radiation Oncology * Biology * Physics Vol. 72, Issue 2, Pages 335-342
- Gregory M.M. Videtic, José S.A. Belderbos, Feng-Ming (Spring) Kong, Lucyna Kepka, et al. Report
From the International Atomic Energy Agency (IAEA) Consultants' Meeting on Elective
Nodal Irradiation in Lung Cancer : Small-Cell Lung Cancer (SCLC). International Journal of
Radiation Oncology * Biology * Physics Vol. 72, Issue 2, Pages 327-334
- Judith van Loon, Dirk De Ruysscher, Rinus Wanders, Liesbeth Boersma, et al. Selective Nodal
Irradiation on Basis of 18FDG-PET Scans in Limited-Disease Small-Cell Lung Cancer: A
Prospective Study. International Journal of Radiation Oncology * Biology * Physics Vol. 77, Issue
2, Pages 329-336
- Annemarie T. Fernandes, Jason Shen, Jarod Finlay, Nandita Mitra, et al. Elective nodal
irradiation (ENI) vs. involved field radiotherapy (IFRT) for locally advanced non-small
cell lung cancer(NSCLC): A comparative analysis of toxicities and clinical outcomes.
Radiotherapy and Oncology Vol. 95, Issue 2, Pages 178-184
A.5.8. TOXICIDAD
- Vivek Mehta .Radiation pneumonitis and pulmonary fibrosis in non–small-cell lung
cancer: Pulmonary function, prediction, and prevention. International Journal of Radiation
Oncology * Biology * Physics Vol. 63, Issue 1, Pages 5-24
- Shulian Wang, Zhongxing Liao, Xiong Wei, Helen H. Liu, et al. Analysis of clinical and
dosimetric factors associated with treatment-related pneumonitis (TRP) in patients
with non–small-cell lung cancer (NSCLC) treated with concurrent chemotherapy and
three-dimensional conformal radiotherapy (3D-CRT). International Journal of Radiation
Oncology * Biology * Physics Vol. 66, Issue 5, Pages 1399-1407
- George Rodrigues, Michael Lock, David D'Souza, Edward Yu, et al.Prediction of radiation
pneumonitis by dose–volume histogram parameters in lung cancer—a systematic
review. Radiotherapy and Oncology Vol. 71, Issue 2, Pages 127-138.
A.5.9. TECNOLOGIA
- Hilke Vorwerk, Gabriele Beckmann, Michael Bremer, Maria Degen, et al. The delineation of
target volumes for radiotherapy of lung cancer patients. Radiotherapy and Oncology Vol.
91, Issue 3, Pages 455-460
- Ursula Nestle, Stephanie Kremp, Anca-Ligia Grosu. Practical integration of [18F]-FDG-PET
and PET-CT in the planning of radiotherapy for non-small cell lung cancer (NSCLC): The
technical basis, ICRU-target volumes, problems, perspectives. Radiotherapy and Oncology
Vol. 81, Issue 2, Pages 209-225
- Janneke P.C. Grutters, Alfons G.H. Kessels, Madelon Pijls-Johannesma, Dirk De Ruysscher, et al.
Comparison of the effectiveness of radiotherapy with photons, protons and carbon-ions
for non-small cell lung cancer: A meta-analysis. Radiotherapy and Oncology Vol. 95, Issue 1,
Pages 32-40
- Zhongxing X. Liao, Ritsuko R. Komaki, Howard D. Thames, Helen H. Liu, et al. Influence of
Technologic Advances on Outcomes in Patients With Unresectable, Locally Advanced
Non–Small-Cell Lung Cancer Receiving Concomitant Chemoradiotherapy. International
Journal of Radiation Oncology * Biology * Physics Vol. 76, Issue 3, Pages 775-781
- Suresh Senan, Dirk De Ruysscher, Philippe Giraud, René Mirimanoff, et al. Literature-based
recommendations for treatment planning and execution in high-dose radiotherapy for
lung cancer. Radiotherapy and Oncology Vol. 71, Issue 2, Pages 139-146
- Lamberto Widesott, Maurizio Amichetti, Marco Schwarz. Proton therapy in lung cancer:
Clinical outcomes and technical issues. A systematic review. Radiotherapy and Oncology
Vol. 86, Issue 2, Pages 154-164
A.5.10. MISCELANEA
- Jacek Jassem. The role of radiotherapy in lung cancer: Where is the evidence?
Radiotherapy and Oncology Vol. 83, Issue 2, Pages 203-213
- N.A. Bayman, H. Sheikh, B. Kularatne, P. Lorigan, F. Blackhall, N. Thatcher, C. Faivre-Finn.
Radiotherapy for small-cell lung cancer—Where are we heading? Lung Cancer, Volume 63,
Issue 3, March 2009, Pages 307-314
- Ben J. Slotman, Suresh Senan. Radiotherapy in Small-Cell Lung Cancer: Lessons Learned
and Future Directions. International Journal of Radiation Oncology * Biology * Physics Vol. 79,
Issue 4, Pages 998-1003
- Neil Bayman, Nooreen Alam, Corinne Faivre-Finn. Radiotherapy for lung cancer in the
elderly. Lung Cancer, Volume 68, Issue 2, May 2010, Pages 129-136
- David Raben, Barb Helfrich, Paul A Bunn. Targeted therapies for non–small-cell lung
cancer: biology, rationale, and preclinical results from a radiation oncology perspective.
International Journal of Radiation Oncology * Biology * Physics Vol. 59, Issue 2, Supplement, Pages
S27-S38
- Branislav Jeremić, Gregory M.M. Videtic. Chest Reirradiation With External Beam
Radiotherapy for Locally Recurrent Non-Small-Cell Lung Cancer: A Review. International
Journal of Radiation Oncology * Biology * Physics Vol. 80, Issue 4, Pages 969-977
- Dirk De Ruysscher, Cary Dehing, Søren M. Bentzen, Ruud Houben, et al. Can we optimize
chemo-radiation and surgery in locally advanced stage III non-small cell lung cancer
based on evidence from randomized clinical trials? A hypothesis-generating study.
Radiotherapy and Oncology Vol. 93, Issue 3, Pages 389-395
- Delaney G, Barton M, Jacob S, Jalaludin B. A model for decision making for the use of
radiotherapy in lung cancer. Lancet Oncol. 2003 Feb;4(2):120-8.