AUTOMATED PERIMETRY DR.JYOTI SHETTY MEDICAL DIRECTOR BANGALORE WEST LIONS EYE HOSPITAL, BANGALORE BASIC CONCEPTS • Traquair's has defined the visual field as been a hill island of vision in a sea of darkness testing along X-Y axes of this 3 dimensional area determines the location in the visual field and along the Z axis identifies the visibility threshold. • X - Y axis - kinetic perimetry • Z axis - static perimetry • Automated Perimetry - " Differential light threshold –Ability to differentiate an illuminated target against an illuminated background." • Threshold Perimetry - Modality of choice BASIC CONCEPTS --- contd THRESHOLD • Luminance of stimuli that is seen 50% of times it is presented • Logarithmic unit dB ( dB prop. 1 / brightness ) • Bracketing strategy ( 4 - 2 - 2 algorithm ) • Supra threshold - 95 % chance a stimulus is seen. • Infra threshold - 5% chance a stimulus is seen. BASIC MACHINE DESIGN • Illuminated hemispherical bowl 33 cm away with target of fixation • Stimuli - spot of light - LED / Projection system / Comp. Video monitor • HFA - II ( 700 Series ) Aspherical bowl 30 cms away ,smaller ,more ergonomic stimuli in periphery more closer, programmed to decrease stimuli brightness (4dB). FIXATION CONTROL • • • CC TV monitor Heijl - Krakau Blind spot method Gaze tracker – – – – – Full time two variable Gaze monitor Image analysis Errors - upward / downward Fixation checked 100 % of stim. Time No testing time for fixation check Basic software design • Strategies for threshold detection – • Intensity of the stimulus presented at a given point is related to the normal threshold at that stimulus site. • Bracketing strategies to define threshold at any point. 4-2-2 algorithm SITA INFORMATION DISPLAY • Numeric data display actual dB value at each point • Gray scale – range of decibels and their corresponding luminance • Difference / Depth defect – actual value is arithmetically subtracted from a presumed expected field. Parameters recommended for testing • Foveal fixation target – small and large diamond with yellow lights. • Goldmann size III target for stimuli & blind spot check. If excessive fixation loss it can be decreased to II or I or if vision less than 6/36 than it can be increased to V. • White stimulus colour • Normal testing speed. can be slow down if patient is slow to response. • Foveal threshold - ON / OFF Threshold tests • Central 30-2 – 76 points are tested . Each point 6 deg apart. Straddling the horizontal and vertical axis so that the 2 inner most test points are 3 deg from fixation point. • Central 24-2 – 56 points are tested . Avoids rim artifacts. • Central 10-2 – 68 points space 2 deg apart. Useful in advance disease with spilt fixation. • Macular threshold test – square grid of 16 points each 2 deg apart , with each point thresholded 3 times. 30 – 2 24 – 2 Macular threshold INTERPRETATION Factors for consistency in testing • Best Refractive correction used. Contact lens to avoid rim artifacts. • Pupil Diameter – at least 3.5 mm in size. • Visual Acuity • Date & Time of testing • Age-For comparison with normative data • Short term fluctuation-Fluctuation occurring within the test. Should be <3dB. INTERPRETATION ----contd. Reliability of patient • Fatigue, anxiety and learning effect • Fixation loss – should be less than 20% • False positive and negative response should be less than 33%. FIXATION LOSSES: 10/12 XX FALSE POS ERRORS : 0/7 FALSE NEG ERRORS :0/6 TEST DURATION : 16:20 Statistical global indices • MD – mean deviation – sensitive to total loss • PSD – pattern standard deviation – sensitive to localized loss. • CPSD – corrected pattern standard deviation – PSD corrected for short term fluctuation. Very sensitive index. Glaucoma defect with automated perimetry- Anderson's Criteria • 3 or more cont.non edge points with >= 5 dB loss • 2 or more cont. non edge points with >=10 dB loss • Diff. of 10 dB across nasal hor. meridian at 2 or more adj. points ( nasal step.) • GHT - ONL • PSD plot - >= 3 pts , p< 5% of which one < 1% • CPSD ( p <5% ) GHT ONL INTERPRETATION ----contd. • • • • • • Progression of defect Test parameters comparable Defect - increased in size / depth >= 7 dB increase in depth of existing defect >= 9 dB depression adj. to abnormal point >= 11 dB depression of a normal point ( New Defect ) • Box plot change analysis • Overview • Glaucoma change probability analysis SWAP • Tests subset of Ganglions affected earlier & selectively -Blue / Yellow • Reduces the redundancy of responsiveness to stimuli • Intense yellow background - bleaches green / red cones • Blue stim. ( 440nm ) - isolates blue cones • Adaptation - 3 mts. Room illumination - minimal • Stimulus size & BS check size V • Mean threshold values lower than SAP - Gray scale darker • Stat Pac probability plots more reliable SWAP -- contd • Field defect precedes SAP by >= 3 yrs • Once abnormal - remain abnormal ( no recovery of damaged blue cones ) • No role in advanced POAG / advanced lenticular changes / colour vision abnormalities • Most useful in younger Glaucoma suspects, OHT , POAG with mild to mod.damage • Time consuming - SITA optimised for SWAP / Fast Pac can be used