RESPIRATION AND GAS EXCHANGE Respiration Aerobic and anaerobic respiration http://www.bbc.co.uk/schools/gcsebitesize/pe/appliedanat omy/1_anatomy_respiratorysys_rev2.shtml Define respiration as the chemical reactions that break down nutrient molecules in living cells to release energy. • Remember respiration is a chemical process • Which releases energy from food • Don’t confuse it with the exchange of gases or breathing State the uses of energy in the body of humans: • • • • • • muscle contraction, protein synthesis, cell division, growth, the passage of nerve impulses the maintenance of a constant body temperature • ALL these processes require energy • You need to be able to quote these Aerobic respiration Define aerobic respiration as the release of a relatively large amount of energy in cells by the breakdown of food substances in the presence of oxygen. • Remember aerobic respiration needs oxygen • It releases a lot of energy State the word equation for aerobic respiration. • Food + oxygen carbon dioxide + water State the equation for aerobic respiration using symbols • C6H12O6 + 6O2 → 6CO2 + 6H2O • Learn this equation • You’ll need it if you’re doing the higher tier Anaerobic respiration Define anaerobic respiration • the release of a relatively small amount of energy by the breakdown of food substances • in the absence of oxygen. • Because the food is not completely broken down some of the energy remains in the waste products State the word equation for anaerobic respiration • • • • • in muscles during hard exercise glucose → lactic acid and the microorganism yeast glucose → alcohol + carbon dioxide Note that a lot of the energy here remains locked up in the lactic acid or alcohol Compare aerobic respiration and anaerobic respiration in terms of relative amounts of energy released. • Aerobic respiration produces much more energy ATP than anaerobic respiration • Look at the diagram below and compare the number of ATP molecules State the balanced equation for anaerobic respiration in • • • • • • • muscles C6H12O6 → 2C3H6O3 and the microorganism yeast C6H12O6 → 2C2H5OH + 2CO2 using symbols You should learn these Note that no carbon dioxide is produced in anaerobic respiration in animals Describe the role of anaerobic respiration in yeast during brewing and bread-making. • http://blowers.chee.arizona.edu/cooking/kine tics/bread.html Bread making The fermentation process serves three primary purposes: • To produce carbon dioxide gas to create a light and airy texture in the bread • To enhance the flavour of the bread • To change the protein structure of the bread to prevent a chewy texture Beer making • Similar to baking bread, yeast is critical to making beer. • Yeast is added to the wort to turn the sugars into alcohol and carbon dioxide • This process is called fermentation. Describe the effect of lactic acid in muscles during exercise (include oxygen debt in outline only). • Lactic acid build up is often blamed for post workout muscle fatigue and pain • During short intense burst of exercise such as sprinting • Energy is generated anaerobically or without oxygen. • Lactic acid builds up • When you stop exercising you are still breathing heavily. • This is your body taking in extra oxygen to 'repay' the oxygen debt. • When you stop sprinting and start to recover you will actually need more oxygen to recover • This is oxygen is used to break down the lactic acid • The difference between the oxygen the body required and what it actually managed to take in during the sudden sprint is called oxygen deficit. Gas exchange List the features of gas exchange surfaces in animals. • Large surface area So diffusion is more efficient • Moist So gases can dissolve • Good blood supply To remove the oxygen and maintain concentration gradient • Ventilation system To bring more supplies of oxygen Cross-section through leaf Circulation of gases in and out of leaf Identify on diagrams and name the larynx, trachea, bronchi, bronchioles, alveoli and associated capillaries • This is a useful website • http://www.bbc.co.uk/schools /gcsebitesize/pe/appliedanato my/1_anatomy_respiratorysys _rev1.shtml The Breathing System • Function is to take air into and out of the lungs to allow gas exchange • Oxygen moves from the lung to the blood • Carbon dioxide moves from the blood into the lung • Gases move by diffusion The Breathing System Rib Sternum Intercostal muscle Cartilage Right lung Backbone Passage of Air Nose Throat Trachea Bronchi Bronchioles Alveoli (air sacs) GAS EXCHANGE The alveoli Explain the role of mucus and cilia in protecting the gas exchange system from pathogens and particles. • Mucus traps the pathogens and particles • Cilia move the mucus upwards to the mouth where it is swallowed The structure of the trachea C-shaped ring of cartilage Ciliated cells The structure of the trachea Ciliated cells and mucussecreting cells •Located in trachea, bronchi and bronchioles •Mucus is produced by goblet cells located in the lining of the air tubes •The mucus traps dirt and microorganisms Ciliated cells and mucussecreting cells •Cilia are tiny hair-like structures on the top layer of cells •Cilia waft dust and mucus out of the lungs •This process protects against infection Describe the role of the ribs, the internal and external intercostal muscles and the diaphragm in producing volume and pressure changes leading to the ventilation of the lungs • You need to learn the sequence of events here When we breathe in… Intercostal muscles contract So, ribcage moves out and up Diaphragm contracts and flattens The volume (or space) inside the thorax increases • The lungs are stretched to fill that space • • • • • The pressure inside the lungs decreases • Now the pressure outside the body is higher than the pressure in the lungs • So, air rushes into the lungs • THE LUNGS INFLATE - This is inhalation When we breathe out… Intercostal muscles relax So, ribcage moves in and down Diaphragm relaxes and curves up The volume (or space) inside the thorax decreases • The lungs are return to their original size • • • • • The pressure inside the lungs increases • Now the pressure inside the lungs higher than the pressure outside the body • So, air rushes out of the lungs • This is exhalation Breathing and gas exchange • http://people.eku.edu/ritchisong/301notes6. htm • There are some good videos here What is lung capacity? • Lung capacity is the maximum volume of air that can be breathed out after a maximum breath in • What is your lung capacity? • Adult male = 4 litres • Adult female = 3 litres State the differences in composition between inspired and expired air. • Not all the oxygen is removed from the air • Exhaled air still contains some oxygen but has much more carbon dioxide and water vapour than inhaled air • http://www.bbc.co.uk/schools/gcsebitesize/pe/appliedanatomy/1_anato my_respiratorysys_rev3.shtml Is exhaled air different? Component Inhaled air Oxygen Carbon dioxide Nitrogen Water vapour Exhaled air 21% 17% 0.04% 4% 78% 78% Variable Saturated Use lime water as a test for carbon dioxide to investigate the differences in composition between inspired and expired air. • Lime water goes cloudy when carbon dioxide is bubbled through it • The experiment below uses a different indicator but lime water could be used with the same apparatus • http://seniorscience.wikispaces.com/file/view /Testing+Exhaled+Air+for+Carbon+dioxide.pdf • Bromothymol blue can be replaced by limewater • Here are the results using limewater • Breathe in and out through the long tube • One tube has inhaled air bubbled through it • The other has exhaled air bubbled through it • http://www.sciencephoto.co m/media/75297/enlarge Investigate and describe the effects of physical activity on rate and depth of breathing • You can try this on yourself or family members • TAKE CARE if anyone has heart or lung problems !!! EFFECT OF EXERCISE ON HEART RATE AND BREATHING • Measure your heart (pulse) rate breathing rate at rest. • Do one lot of exercise (10 press ups OR run or walk up one flight of stairs) • Take the pulse and breathing rate again • Wait till you have fully recovered and your pulse has gone back to normal • Then do 2 lots of exercise (20 press ups OR run/walk up two flights of stairs) • Repeat with three and four lots of exercise. RESULTS • Plot a graph of heart rate against amount of exercise • Plot another graph of breathing rate against exercise • Plot a scatter graph of heart rate against pulse rate • You could try this with other members of your family or friends Conclusions • What are trends in your results? • In a couple of sentences explain the relationship between exercise, heart rate and breathing rate. • What is the biological explanation for your results? Evaluation • Look at your method and explain whether or not this was an accurate measure of the effects of exercise on the heart and lungs. • Suggest some improvements to this experiment • Write up and send me your experiment Explain the link between physical activity and rate and depth of breathing • in terms of • changes in the rate at which tissues respire • and therefore of carbon dioxide concentration • and pH in tissues • and in the blood Effects of exercise The body needs much more Oxygen. The breathing becomes faster and deeper and produces a large vol. of Oxygen. More Carbon Dioxide is produced which is the waste product, which blood carries back to the lungs to be exhaled Because the body needs more blood to carry more Oxygen and waste products the blood is diverted from parts of the body that don’t require it for example the blood in the stomach is reduced. More H2O and heat are produced and eliminated by sweating and exhaling. The blood must carry these waste products away from the muscle cells, this is why the breath is hot and moist during exercise. Muscles are required to contract and relax in specific areas of the body. People taking part in exercise go red because the Veins carrying warm blood back to the heart divert the blood nearer the skins surface. This is called Vasodilation. The heat is then lost through radiation through the skin. The heart beats faster and pumps blood around the body faster. The heart also fills up with more blood and squeezes more blood out with each contraction. The Heart Rate, Stroke Vol., Cardiac Output, and Blood Pressure all increase during exercise. Effects on pH • The pH of the blood is maintained at about pH 7 • When carbon dioxide (CO2) gas dissolves in water, it forms carbonic acid • This lowers the blood pH • The pH of the tissue fluid also lowers • This is detected by the brain which increases the heart and breathing rate What happens when we exercise? • Exercise increases the rate of which process? RESPIRATION • Why? More energy needed for muscle contraction • How? ATP is formed when food is broken down. This releases more carbon dioxide How does the breathing system respond to exercise? • Exercise causes the rate and depth of breathing to increase • The heart rate increases • The stroke volume of the heart increases • This increases the supply of oxygen and glucose to the muscles • And increases the rate of removal of carbon dioxide, lactic acid and heat from the muscles EFFECT OF EXERCISE ON HEART RATE AND BREATHING • Measure your heart (pulse) rate breathing rate at rest. • Do one lot of exercise (10 press ups OR run or walk up one flight of stairs) • Take the pulse and breathing rate again • Wait till you have fully recovered and your pulse has gone back to normal • Then do 2 lots of exercise (20 press ups OR run/walk up two flights of stairs) • Repeat with three and four lots of exercise. Describe the effects of tobacco smoke and its major toxic components on the gas exchange system. • • • • • tar, nicotine, carbon monoxide, smoke particles http://www.bbc.co.uk/schools/ks3bitesize/sci ence/organisms_behaviour_health/diet_drugs /revise7.shtml Smoking Tar • Tar causes cancer of the lungs, mouth and throat. • It coats the surface of the breathing tubes and the alveoli. • This causes coughing and damages the alveoli, making it more difficult for gas exchange to happen. Smoke • Cells in the lining of the breathing tubes produce sticky mucus to trap dirt and microbes. • Cells with tiny hair-like parts, called cilia, normally move the mucus out of the lungs. • Hot smoke and tar from smoking damages the cilia. • So smokers cough to move the mucus and are more likely to get bronchitis. Nicotine • Nicotine is addictive - it causes a smoker to want more cigarettes. • Nicotine also increases the heart rate and blood pressure, and makes blood vessels narrower than normal. • This can lead to heart disease. Carbon monoxide • Carbon monoxide is a gas that takes the place of oxygen in red blood cells. • This reduces the amount of oxygen that the blood can carry. • This means that the circulatory system has to work harder, causing heart disease.