Mitosis, Meiosis, and Life Cycles Chapter 12 KEY TERMS • DIPLOID (2N) • • • The condition of having two sets of chromosomes per nucleus In somatic cells of diploid organisms, chromosomes are present in pairs HAPLOID (N) • The condition of having one set of chromosomes per nucleus KEY TERMS • HOMOLOGOUS CHROMOSOMES • Members of a chromosome pair that are similar in size, shape, and genetic constitution KEY TERMS • CELL CYCLE • Cyclic series of events in the life of a dividing eukaryotic cell KEY TERMS • INTERPHASE • Stage of the cell cycle between successive mitotic divisions Interphase • During interphase • • • cell grows and prepares for next division DNA replicates Interphase is divided into • • • first gap phase (G1) synthesis phase (S) second gap phase (G2) KEY TERMS • MITOSIS • Division of the cell nucleus resulting in two daughter nuclei, each with the same number of chromosomes as the parent nucleus KEY TERMS • CYTOKINESIS • Stage of cell division in which the cytoplasm divides to form two daughter cells Cell Cycle Stages of Mitosis • • • • Prophase Metaphase Anaphase Telophase Prophase • Chromatin condenses into chromosomes • • • • Nucleolus disappears Nuclear envelope breaks down Mitotic spindle begins to form At the end of prophase, each duplicated chromosome is composed of two sister chromatids A Duplicated Chromosome KEY TERMS • SPINDLE • Structure consisting mainly of microtubules that provides the framework for chromosome movement during cell division Metaphase • Duplicated chromosomes line up along midplane of cell Anaphase • Sister chromatids separate and move to opposite poles of the cell • Each chromatid is now a separate chromosome Telophase • Nuclear envelope forms around each set of chromosomes • • • Nucleoli reappear Chromosomes lengthen and become chromatin Spindle disappears KEY TERMS • CELL PLATE • • Structure that forms during cytokinesis in plants, separating two daughter cells produced by mitosis Cytokinesis generally takes place in telophase Cytokinesis Interphase and Mitosis (a) Interphase (b) Prophase (c) Metaphase Condensing Spindle chromosome microtubules (consists of 2 sister chromatids) (d) Anaphase (e) Telophase Sister chromatids Cell New (now called plate nuclei chromosomes) move to opposite Stepped Art ends of cell Fig. 12-2, p. 244 KEY TERMS • MEIOSIS • • Process in which a 2n cell undergoes successive nuclear divisions, potentially producing four n nuclei Leads to formation of spores in plants Meiosis • Meiosis must occur at some time in the life of a sexually reproducing organism if gametes are to be haploid • Meiosis consists of two cell divisions • • Meiosis I Meiosis II Meiosis I • Members of each homologous pair of chromosomes separate and are distributed into separate nuclei in two daughter cells • Chromosomes were duplicated prior to meiosis I, so each consists of two chromatids Meiosis II • Chromatids separate into individual chromosomes and are distributed into different haploid daughter cells • Four haploid cells form KEY TERMS • SYNAPSIS • Physical association of homologous chromosomes during prophase I of meiosis Crossing Over • Crossing over • • Exchange of segments of homologous chromosomes Synapsis and crossing over occur during prophase I of meiosis Crossing Over Meiosis Meiosis LEARNING OBJECTIVE • Compare and contrast mitosis and meiosis Mitosis • Involves a single nuclear division in which the two daughter cells formed are genetically identical to each other and to the original cell • Synapsis of homologous chromosomes does not occur during mitosis Meiosis • Involves two successive nuclear divisions and forms four haploid cells, each with a different combination of genes • Synapsis of homologous chromosomes occurs during prophase I of meiosis Mitosis and Meiosis KEY TERMS • Alternation of generations • • SPOROPHYTE • • Plants alternate haploid and diploid generations 2n, spore-producing stage in plant life cycle GAMETOPHYTE • n, gamete-producing stage in plant life cycle The Sporophyte • The 2n, spore-producing stage in the life cycle of a plant • A diploid sporophyte plant forms haploid spores by meiosis • A spore divides mitotically to form a haploid gametophyte plant The Gametophyte • The n, gamete-producing stage in the life cycle of a plant • The gametophyte produces haploid gametes by mitosis • Two gametes fuse to form a diploid zygote, which divides mitotically to produce a diploid sporophyte Plant Life Cycle