• Know that cell division by meiosis results in the formation of gametes .
• Can describe the importance of meiosis in creating variation by independent assortment of chromosomes and crossing over .
• Know that cell division by mitosis results in an increase in number of identical cells for growth and repair .
• Identify and name the stages of mitosis in diagrams and photomicrographs.
• Describe the cell cycle and relate it to an understanding of cancer and its treatment.

Replication of chromosomes occurs prior to division
Homologous chromosomes centromere chromatids chromosome

Meiosis 1 Meiosis 2

Homologous chromosomes associate

• Know that cell division by meiosis results in the formation of gametes .
• Describe the importance of meiosis in creating variation by independent assortment of chromosomes and crossing over .
• Know that cell division by mitosis results in an increase in number of identical cells for growth and repair .
• Identify and name the stages of mitosis in diagrams and photomicrographs.
• Describe the cell cycle and relate it to an understanding of cancer and its treatment.

Independent segregation increases variation paternal maternal
Random assortment in meiosis I
Random assortment in meiosis II

maternal paternal
Random assortment in meiosis I
Random assortment in meiosis II

recombinant chromosome chiasma
In the first division of meiosis the homologous chromosomes associate

B B b b
G g G g
B, G B, g b, G b, g
All gametes have a different combination of alleles on the chromosomes

• Know that cell division by meiosis results in the formation of gametes .
• Can describe the importance of meiosis in creating variation by independent assortment of chromosomes and crossing over .
• Know that cell division by mitosis results in an increase in number of identical cells for growth and repair .
• Identify and name the stages of mitosis in diagrams and photomicrographs.
• Describe the cell cycle and relate it to an understanding of cancer and its treatment.

Mitosis produces two identical daughter cells.
metaphase prophase anaphase interphase cytoplasmic division (cytokinesis) telophase

M
I
T
O
S
I
S interphase prophase metaphase anaphase telophase cytokinesis
Chromosomes appear, nucleus disappears
Chromatids pulled to poles
Chromosomes invisible; DNA replicates
Cytoplasmic division
Chromosomes at equator, spindle forms
Chromatids at poles, nucleus reforms

• Know that cell division by meiosis results in the formation of gametes .
• Can describe the importance of meiosis in creating variation by independent assortment of chromosomes and crossing over .
• Know that cell division by mitosis results in an increase in number of identical cells for growth and repair .
• Identify and name the stages of mitosis in diagrams and photomicrographs.
• Describe the cell cycle and relate it to an understanding of cancer and its treatment.

interphase nuclear division anaphase
G1:
Growth of daughter cell
Duplication of organelles other than nucleus
G2:
Cell checks
DNA and makes any repairs. Cell prepares for division
S:
Replication of DNA

• Meoisis produces haploid gametes that are genetically different.
Variation is further increased by independent segregation of chromosomes and crossing over forming recombinant chromosomes.
• Mitosis is the nuclear division which produces 2 genetically identical, diploid cells. It consists of prophase, metaphase, anaphase and telophase.
• Cell cycle consists of interphase, nuclear division (mitosis or meiosis) and cytplasmic division (cytokinesis).
• Cancer is caused by mutation of genes that regulate the cell cycle and treatment is designed to inhibit cell division.