Protein Synthesis Test – Tomorrow! Meiosis Similarities and Differences between Mitosis and Meiosis Mitosis Where does it occur in body? # Cell divisions # DNA replications Creates what type of cell? # Chromosomes in End product # Cells produced Function Meiosis Mitosis Review • IPMAT • Remember: Mitosis = Two Cells “Tea for Two” Reasons for Mitosis • Production of 2 daughter cells that are genetically identical • Provides: – a) a means of asexual reproduction for unicellular organisms – b) replacement of worn out and damaged cells – c) growth of an organism Zygote Zygote 2n 2n From Zygote to Embryo Cleavage Blastula From Zygote to Embryo Meiosis • Special type of cell division that produces haploid (n) sex cells (gametes) • Meiosis is divided into 2 stages: Meiosis I and Meiosis II • Consists of 1 replication and 2 divisions Formation of gametes 46 23 46 23 How many chromosomes will baby have? Germ Cells • Male – Sperm producing machines – Germ cells are found in the lining of the seminiferous tubules (250m in each testicle) – Once they reach maturity, they constantly divide (Spermatogenesis) • Female – Germ cells - found in follicles in ovaries and produced before birth – Cells are suspended in Prophase I and don’t continue to divide until puberty – Complete their division after being simulated by hormones during the menstrual cycle (Oogenesis) Male Female Similarities and Differences between Mitosis and Meiosis Mitosis Where does it occur in body? # Cell divisions # DNA replications Creates what type of cell? # Chromosomes in End product # Cells produced Function Meiosis Let’s carry out an example for a mosquito cell Diploid Number (2n) = 6 Interphase I • Period of growth of germ cells • DNA replicates Early Interphase I Late Interphase I Prophase I • Nuclear envelope disappears • Replicated chromatin coils into chromatid pairs • Centrioles move to opposite poles of the cell and start producing protein fibers that form the spindle Prophase I • Synapsis – Chromatid pairs attach to form tetrads • Crossing over – During synapsis, arms of chromatid pairs exchange segments of DNA at chiasma – Increases genetic diversity Prophase I Early Prophase I Late Prophase I Meiosis I – Metaphase I • Tetrads line up at the equator of spindles Meiosis I – Anaphase I • Tetrads separate in an event called disjunction • Chromatid pairs are pulled to poles of cell • Cleavage furrow begins to form Meiosis I – Telophase I • Cleavage furrow formation is complete and cytokinesis occurs • Nuclear envelope reappears Meiosis II – Prophase II • Most cells skip Interphase II and proceed right into Prophase II • Meiosis II follows the stages of Mitosis Meiosis II – Metaphase II Meiosis II – Anaphase II Meiosis II – Telophase II Differences of Meiosis and Mitosis • Synapsis – Happens in Prophase I – Tetrad formation • Crossing over – Happens in Prophase I – Arms of chromatids in a tetrad swap DNA – Increases genetic diversity • Disjunction – Happens in Anaphase I – Tetrads separate and chromatid pairs are pulled to opposite sides of the cell • Non-Disjunction – Happens in Anaphase I – A tetrad does not separate and sex cells are formed with abnormal chromosome numbers Meiosis Square Dance Step by Step Meiosis Animation Dry Lab In which phases will these terms be present? • • • • • Chromatin Replicated Chromatin Chromatid Pairs Tetrads Chromosomes Draw the stages of Meiosis from Metaphase I to Telophase II if nondisjunction were to occur