HUMAN TECHNOLOGY GENETICALLY MODIFIED ORGANISMS, ARTIFICIAL SELECTION, SELECTIVE BREEDING, ANIMAL HUSBANDRY, GENE THERAPY VIDEO • http://bcove.me/hmp88kls ESSENTIAL QUESTION: HOW HAVE HUMANS USED TECHNOLOGIES TO INFLUENCE THE INHERITANCE OF DESIRED TRAITS IN ORGANISMS? • Genetic Modification • Animal Husbandry • GM stands for 'genetically-modified‘ • Selective Breeding of animals only • describes the process by which scientists are able to pinpoint the individual gene • Concerned with the production and care of domestic animals • Remove gene, copy it, place it in new organism • produces a desired outcome • Selective Breeding • the intentional mating of two animals or plants • produces offspring with desirable traits • Can also get rid of unwanted traits • Gene Therapy • Technique that uses genes to treat or prevent disease. • May allow doctors to treat a disorder by putting a gene into a patient’s cells • No need for drugs or surgery. GENETICALLY MODIFIED ORGANSIMS REASONS FOR GENETICALLY MODIFYING ORGANISMS • Produce faster growing crops or animals • Produce plants that are more resistant to pests • Rainbow Papaya • Research: • Drug development • Commercial reasons • Fluorescent fish for pets • Produce crops that are drought resistant • Increase yield of crop • Produce foods that stay ripe longer • Reduce cost that is passed to consumer • Endless Summer Tomato • Enhance the nutritional value of a food • Golden Rice PROCESS TO MAKE GENETICALLY MODIFIED ORGANISMS • The first GMOs were bacteria in the early 1970s. • Most basic modifications are designed and prepared using bacteria (usually E.Coli) and then transferred to the target organisms. CONTROVERSY OF GENETICALLY MODIFIED ORGANISMS • Controversy over GMOs in general: • Genetic modification is placing the genes of one species into another unrelated species. • Some modifications are created by corporations to make crops resistant to pests or to certain chemicals. • Controversy over GM foods: • Have they been tested enough to prove they are safe? • • Could pesticide resistant plants become toxic? Could peanut genes inserted into soybeans cause unexpected allergic reactions? • What evidence is there of problems with GM crops? • Some studies have shown negative results for lab animals that ate GMO foods. • Those foods were not meant for human consumption • There are not very many studies that show these negative results. • Other scientists have criticized and questioned some of these studies. • Video http://www.cbsnews.com/news/gmo-food-labeling-inside-thecontroversy/ PROS AND CONS OF GMO FOOD • Pros • Higher crop yields • Reduced need for herbicides and pesticides • Improved food quality • Increased nutritional value • Cons • Possible allergies • Unpredicted changes to the ecosystem • Chance of new diseases developing SELECTIVE BREEDING AND ANIMAL HUSBANDRY REASONS FOR SELECTIVE BREEDING • Improve food production • • • • Better able to fight off pests More fit and stronger animals Cows that give more milk Chickens that lay bigger eggs • Selective Breeding – Plants and Animals • Animal Husbandry – Animals only • Typically for farming and agriculture We choose the characteristics we want: • Dogs with a good sense of smell, hearing etc. PROCESS OF SELECTIVE BREEDING • Decide which characteristics are important • Choose parents that show these characteristics • Select the best offspring from parents to breed the next generation • Repeat the process continuously • Human controlled Natural Selection/Evolution CONTROVERSIES OF SELECTIVE BREEDING • Animal Rights: • Should animals have the right to select their own breeding partners? • Unnatural • It doesn’t occur in nature, does that make it wrong? • Benefits to humanity • Better/more plentiful food. • Service animals • Humans have been using selective breeding for thousands of years already. GENE THERAPY REASONS FOR GENE THERAPY • To alter genes to correct genetic defects • prevent or cure genetic diseases. • Not to be confused with Genetic engineering which changes the genes to make the organism better than normal. • Possibility to cure deadly diseases like cancer PROCESS OF GENE THERAPY Three different ways: • Replacing a mutated gene that causes disease with a healthy copy of the gene • Inactivating, or “knocking out,” a mutated gene that is functioning improperly • Introducing a new gene into the body to help fight a disease CONTROVERSIES OF GENE THERAPY • Pros: • Could wipe out genetic diseases • Prevent genetic disorders in future generations for families who know they have it in their bloodline • Cons: • Still a dangerous and difficult process • When used in unborn children, not sure of effects • Child doesn’t have a choice