Pregnancy and its Effects on Oral health Pamela Rettig RDH, MS Indiana University School of Dentistry Objectives At the completion of this session the audience will be able to : Identify the clinical and oral health changes associated with pregnant patients Understand the importance of preventive care during pregnancy Discuss alterations in dental care for the pregnant patient. What Happens During Pregnancy? Lowered Immune response to specific dental disease Increased Risk for Diabetes Associated with periodontal disease Changes in dietary habits Need to alter treatment of dental disease Pregnancy and Gingival Disease Clarification Pregnancy itself does not cause gingivitis or periodontal disease. Gingivitis and periodontal disease in pregnancy is caused by bacterial plaque. Pregnancy accentuates the gingival response to plaque. What is it gingivitis clinically? Gingivitis is an early stage of periodontal disease causing the gums to swell. Gingivitis is a reversal condition that can be treated by the debridement of dental plaque Research shows Gingivitis present 50-100% during pregnancy Severity of gingival disease increases during pregnancy in second and third trimesters Pregnancy Gingivitis Red gums Pregnancy Gingivitis Pregnancy Gingivitis Edema Pyrogenic granuloma What happens if Gingivitis is untreated? Periodontal Disease Gums separate from the tooth forming pockets and depended spaces. Bone and supporting soft tissue are destroyed Teeth can become loose Contributing Factors During Pregnancy Poor Oral Hygiene Diabetes Smoking Pregnancy Increased Risk Increase in estrogen and progesterone Alters gingival connective tissue response and immune response to oral bacteria What is the big deal with gingival disease and pregnancy? Adverse Pregnancy Outcomes Premature delivery Low birth weight infants Gestational diabetes Preeclampsia Data A systematic review of the literature in 2006 examined the relationship between periodontal disease and adverse pregnancy outcomes: 44 studies 29 suggested an increase risk in adverse pregnancy outcomes 15 studies showed no association Preterm Deliveries/Low Birth Weight Periodontal disease provides a source of gram negative anaerobic organisms and bacteria Triggers release of immune modulators – stimulates prostaglandin E 2 Can trigger uterine contractions Periodontal disease increases C-reactive protein plasma levels which can induce labor Periodontal Disease and Gestational Diabetes American Diabetes Association indicates gestational diabetes exists with 1 – 14% of all pregnancies Individuals with diabetes are more likely to have periodontal disease Periodontal infections may adversely affect glycemic levels Pregnant women with periodontal disease are more likely to develop gestational diabetes than those women with healthy gums Research A study followed 256 women through their first six months of pregnancy 22 women developed gestational diabetes Women with diabetes had higher levels of periodontal bacteria than those without gestational diabetes Preeclampsia Complication of pregnancy Cause perinatal mortality 5-8% of all pregnancies Periodontal Disease and Preeclampsia Periodontal pathogens can travel to the uteroplacental area Placental inflammation / oxidative stress Placental damage leading to preeclampsia Preexisting preeclampsia can be aggravated by periodontal disease Research A case control study found that 82% of preeclamptic women had severe periodontal disease. Dental Erosion • Occurs after extensive vomiting • Acid attacks teeth • Loss of enamel Dental Caries Pregnancy changes dietary habits. More frequent snacks Many times increase in carbohydrates Causes increase in dental caries Treatment Considerations First Trimester Second trimester Third Trimester Plaque Control Plaque Control Plaque control Oral Hygiene Instruction Oral Hygiene Instruction Oral Hygiene Instruction Scaling, polishing Scaling, polishing Scaling, polishing Avoid elective treatment, urgent care only Routine Dental care Routine Dental care Dental Radiographs One of the most controversial areas in management of the pregnant patient It well documented radiation should be avoided during the first trimester due to developing fetus most susceptible to radiation damage Second and Third trimester if radiographs are needed to confirm diagnosis Abscess Local Anesthetics Another controversial area Concern drug may cross the placenta and be toxic or teratogenic to fetus. Class B Local Anesthetics Etidocaine Lidocaine Prilocaine Dental Management Considerations for Patients Who Are Pregnant 1. Evaluate patient; determine trimester and health status. 2. Confirm that medical prenatal care was provided, or facilitate entry into medical care. 3. Provide periodontal therapy and oral hygiene instructions. 4. Educate the patient: Discuss the importance and benefits of good plaque control and fluoride. 5. Minimize radiographic exposure. 6. Minimize drug use. Drug selection should be based on safety profile, risk to mother and fetus, and potential for interactions and adverse effects. 7. Avoid prolonged appointment time in the dental chair (i.e., risk of supine hypothesion). 8. The safest time for provision of dental treatment is the second trimester. Table 1 Periodontal disease in pregnancy: review of the evidence and prevention strategies. Lachat MF; Solnik AL; Nana AD; Citron TL Journal of Perinatal & Neonatal Nursing. 25(4):3129, 2011 Oct-Dec. Table 1 . Promoting oral health during pregnancy © 2011 Lippincott Williams & Wilkins, Inc. 2