Pharmacology
CRT 11? = 8%
RRT 6?
A 30-year-old patient presents to the asthma clinic with a 2-week
history of daily wheezing and nightly awakenings with
shortness of breath. The patient is using Primatene Mist five
times daily and fluticasone propionate (Flovent) 110 MDI
occassionally at night. How should the therapist counsel the
patient regarding disease management?
I. Discontinue Primatene Mist
II. Use fluticasone propionate (Flovent) 110 MDI, 2 puffs twice
daily.
III. Use salmeterol (Serevent) dry powder inhaler, 1 dose twice
daily.
IV. Use fluticasone propionate/salmeterol (Advair) 100/50 dry
powder inhaler, one dose daily.
A.
B.
C.
D.
I, II, and III only
I, II, and IV only
I, III, and IV only
II, III, and IV only
A 30-year-old patient presents to the asthma clinic with a 2-week
history of daily wheezing and nightly awakenings with
shortness of breath. The patient is using Primatene Mist five
times daily and fluticasone propionate (Flovent) 110 MDI
occassionally at night. How should the therapist counsel the
patient regarding disease management?
I. Discontinue Primatene Mist
II. Use fluticasone propionate (Flovent) 110 MDI, 2 puffs twice
daily.
III. Use salmeterol (Serevent) dry powder inhaler, 1 dose twice
daily.
IV. Use fluticasone propionate/salmeterol (Advair) 100/50 dry
powder inhaler, one dose daily.
A.
B.
C.
D.
I, II, and III only
I, II, and IV only
I, III, and IV only
II, III, and IV only
Which of the following is associated with the
administration of aerosolized pentamidine
isethionate (NebuPent)?
A.tachycardia
B.bradycardia
C.bronchospasm
D.hypotension
Which of the following is associated with the
administration of aerosolized pentamidine
isethionate (NebuPent)?
A.tachycardia
B.bradycardia
C.bronchospasm
D.hypotension
An increase in a patient's heart rate during
aerosolized bronchodilator therapy is
primarily a result of which of the following
drug effects?
A.alpha only
B.beta 1 only
C.beta 2 only
D.beta 1 and beta 2 only
An increase in a patient's heart rate during
aerosolized bronchodilator therapy is
primarily a result of which of the following
drug effects?
A.alpha only
B.beta 1 only
C.beta 2 only
D.beta 1 and beta 2 only
Which of the following devices are most
commonly used to deliver aerosols by the
inhalation route?
I. Dry powder inhaler
II. Metered dose inhaler
III. Small-volume nebulizer
IV.Slip-stream nebulizer
A. I and III
B. II and IV
C. I, II, and III
D. I, II, III, and IV
Which of the following devices are most
commonly used to deliver aerosols by the
inhalation route?
I. Dry powder inhaler
II. Metered dose inhaler
III. Small-volume nebulizer
IV.Slip-stream nebulizer
A. I and III
B. II and IV
C. I, II, and III
D. I, II, III, and IV
Which of the following are the largest single group
of drugs among aerosolized agents used for
inhalation?
A.
Inhaled corticosteroids
B.
Adrenergic bronchodilators
C.
Mucus-controlling agents
D.
Anticholinergic bronchodilators
Which of the following are the largest single group
of drugs among aerosolized agents used for
inhalation?
A.
Inhaled corticosteroids
B.
Adrenergic bronchodilators
C.
Mucus-controlling agents
D.
Anticholinergic bronchodilators
Which of the following is an indication for use of
an adrenergic bronchodilator?
A.Treatment of excessive, viscous mucus
secretions
B.Antiinflammatory treatment of mild to moderate
persistent asthma
C.Treatment of reversible airflow obstruction
D.Prophylactic management of asthma
Which of the following is an indication for use of
an adrenergic bronchodilator?
A.Treatment of excessive, viscous mucus
secretions
B.Antiinflammatory treatment of mild to moderate
persistent asthma
C.Treatment of reversible airflow obstruction
D.Prophylactic management of asthma
Proventil and Ventolin are brand names for which
of the following beta-adrenergic bronchodilators?
A.
Albuterol
B.
Isoetharine
C.
Terbutaline
D.
Metaproterenol
Proventil and Ventolin are brand names for which
of the following beta-adrenergic bronchodilators?
A.
Albuterol
B.
Isoetharine
C.
Terbutaline
D.
Metaproterenol
An MDI of Salmeterol delivers which of the
following?
A.
131 mg/puff
B.
90 mg/puff
C.
65 mg/puff
D.
25 mg/puff
An MDI of Salmeterol delivers which of the
following?
A.
131 mg/puff
B.
90 mg/puff
C.
65 mg/puff
D.
25 mg/puff
Which of the following short-acting catecholamines
are used for their strong alpha1 vasoconstricting
effects to reduce swelling in the nose and larynx
and to control bleeding during bronchoscopic
biopsy?
A.
Isoproterenol
B.
Isoetharine
C.
Dobutamine
D.
Racemic epinephrine
Which of the following short-acting catecholamines
are used for their strong alpha1 vasoconstricting
effects to reduce swelling in the nose and larynx
and to control bleeding during bronchoscopic
biopsy?
A.
Isoproterenol
B.
Isoetharine
C.
Dobutamine
D.
Racemic epinephrine
Which of the following are side effects of newer,
more beta2-selective bronchodilators?
A.
Tremor
B.
Insomnia
C.
Nervousness
D.
All the above
Which of the following are side effects of newer,
more beta2-selective bronchodilators?
A.
Tremor
B.
Insomnia
C.
Nervousness
D.
All the above
What are some potential adverse effects with use
of adrenergic bronchodilators?
I. Hypokalemia
II. Dizziness
III. Worsening ventilation/perfusion ratio (V/Q)
IV.Bradycardia
A. I and IV only
B. II and III only
C. I, II, and III
D. I, II, III, and IV
What are some potential adverse effects with use
of adrenergic bronchodilators?
I. Hypokalemia
II. Dizziness
III. Worsening ventilation/perfusion ratio (V/Q)
IV.Bradycardia
A. I and IV only
B. II and III only
C. I, II, and III
D. I, II, III, and IV
Which of the following are assessment features for
evaluating patient response to bronchodilator therapy?
I. Reversibility of airflow obstruction
II. Changes in flow rates using a peak flow meter or
portable spirometry
III. Vital-sign changes (e.g., blood pressure, pulse rate)
IV. Changes in ventilation and oxygenation by arterial
blood gas or pulse oximeter
V. The patient's subjective reaction to treatment
A.
B.
C.
D.
II, III, and IV
II, III, and V
I, II, III, and V
I, II, III, IV, and V
Which of the following are assessment features for
evaluating patient response to bronchodilator therapy?
I. Reversibility of airflow obstruction
II. Changes in flow rates using a peak flow meter or
portable spirometry
III. Vital-sign changes (e.g., blood pressure, pulse rate)
IV. Changes in ventilation and oxygenation by arterial
blood gas or pulse oximeter
V. The patient's subjective reaction to treatment
A.
B.
C.
D.
II, III, and IV
II, III, and V
I, II, III, and V
I, II, III, IV, and V
What amount of Ipratropium bromide (Atrovent) is
delivered by MDI?
A.
10 mg/puff
B.
15 mg/puff
C.
18 mg/puff
D.
90 mg/puff
What amount of Ipratropium bromide (Atrovent) is
delivered by MDI?
A.
10 mg/puff
B.
15 mg/puff
C.
18 mg/puff
D.
90 mg/puff
What is the dosage for Ipratropium bromide
(Atrovent)?
A.
2 puffs qid
B.
2 puffs tid
C.
2 puffs bid
D.
2 puffs q12h
What is the dosage for Ipratropium bromide
(Atrovent)?
A.
2 puffs qid
B.
2 puffs tid
C.
2 puffs bid
D.
2 puffs q12h
What are some common side effects seen with
Ipratropium bromide (Atrovent)?
A.
Tachycardia
B.
Blood pressure increase
C.
Cough and dry mouth
D.
Tolerance
What are some common side effects seen with
Ipratropium bromide (Atrovent)?
A.
Tachycardia
B.
Blood pressure increase
C.
Cough and dry mouth
D.
Tolerance
Which of the following are indications for use of
acetylcysteine (Mucomyst)?
I. Treatment of acetaminophen overdose
II. Treatment of excessive, viscous mucus
secretions
III. Treatment of aspirin overdose
IV.Treatment of purulent mucus secretions by
breaking up DNA
A. I and II only
B. II and IV only
C. I, II, and III
D. I, II, III, and IV
Which of the following are indications for use of
acetylcysteine (Mucomyst)?
I. Treatment of acetaminophen overdose
II. Treatment of excessive, viscous mucus
secretions
III. Treatment of aspirin overdose
IV.Treatment of purulent mucus secretions by
breaking up DNA
A. I and II only
B. II and IV only
C. I, II, and III
D. I, II, III, and IV
Acetylcysteine (Mucomyst) lowers the viscosity of
mucus by means of which of the following?
A.Breaking down DNA
B.Increasing the osmolarity of the mucus and
pulling water into it
C.Changing the pH of the mucus, causing it to
break down
D.Substituting its sulfhydryl group for disulfide
bonds and breaking a portion of the bond
forming the gel structure
Acetylcysteine (Mucomyst) lowers the viscosity of
mucus by means of which of the following?
A.Breaking down DNA
B.Increasing the osmolarity of the mucus and
pulling water into it
C.Changing the pH of the mucus, causing it to
break down
D.Substituting its sulfhydryl group for disulfide
bonds and breaking a portion of the bond
forming the gel structure
Which of the following should be assessed when delivering
acetylcysteine (Mucomyst)?
I. Presence of adverse effects that require treatment to
be discontinued
II. Monitoring peak flow changes
III. Monitoring color, consistency, and amount of sputum
IV. Monitoring for presence of hydrogen sulfide (a rotten
egg odor), which means that the acetylcysteine
(Mucomyst) is no longer active
A.
B.
C.
D.
I and III only
I, II, and III
II, III, and IV
I, II, III, and IV
Which of the following should be assessed when delivering
acetylcysteine (Mucomyst)?
I. Presence of adverse effects that require treatment to
be discontinued
II. Monitoring peak flow changes
III. Monitoring color, consistency, and amount of sputum
IV. Monitoring for presence of hydrogen sulfide (a rotten
egg odor), which means that the acetylcysteine
(Mucomyst) is no longer active
A.
B.
C.
D.
I and III only
I, II, and III
II, III, and IV
I, II, III, and IV
Which of the following are true regarding
glucocorticoids?
I. They work through activation of intracellular
receptors.
II. Relief is immediate.
III. Daily compliance is essential to controlling
inflammation in asthma.
IV. Taken intranasally they can control allergic and
nonallergic rhinitis.
A. I, II, and III
B. I, III, and IV
C. II, III, and IV
D. I, II, III, and IV
Which of the following are true regarding
glucocorticoids?
I. They work through activation of intracellular
receptors.
II. Relief is immediate.
III. Daily compliance is essential to controlling
inflammation in asthma.
IV. Taken intranasally they can control allergic and
nonallergic rhinitis.
A. I, II, and III
B. I, III, and IV
C. II, III, and IV
D. I, II, III, and IV
How does cromolyn sodium work?
A.Producing antiinflammatory enzymes within
cells
B.Inhibiting degranulation of mast cells
C.Preventing arachidonic acid formation from
activation of mast cell membrane
phospholipase A2
D.Leukotriene inhibition
How does cromolyn sodium work?
A.Producing antiinflammatory enzymes within
cells
B.Inhibiting degranulation of mast cells
C.Preventing arachidonic acid formation from
activation of mast cell membrane
phospholipase A2
D.Leukotriene inhibition
Which of the following is true about the use of
Ribavirin?
I. It is used as an antiviral agent against influenza.
II. It is delivered by a SPAG unit.
III. Adverse effects include skin rash, conjunctivitis,
and eyelid erythema.
IV.It can occlude endotracheal-tube and ventilator
exhalation valves.
A. I, and II only
B. III and IV only
C. II, III, and IV
D. I, II, III, and IV
Which of the following is true about the use of
Ribavirin?
I. It is used as an antiviral agent against influenza.
II. It is delivered by a SPAG unit.
III. Adverse effects include skin rash, conjunctivitis,
and eyelid erythema.
IV.It can occlude endotracheal-tube and ventilator
exhalation valves.
A. I, and II only
B. III and IV only
C. II, III, and IV
D. I, II, III, and IV