Diabetes Mellitus Dr David Carmody Specialist Registrar in Diabetes and Endocrinology South Infirmary Victoria University Hospital How Common Now How Common 2025 Who Cares Introduction 2 • Association between Diabetes and CVS • INSERT Graph x 1 What must I know? • Diagnosis • Types/ Causes • Treatments • Complications What must I know? • Diagnosis • Types/ Causes • Treatments • Complications Diagnosis mmol/l 7 11.1 Diagnosis mmol/l 1. Fasting 2. 75g OGTT 3. Random Greater than or equal to!!! What must I know? • Diagnosis • Types/ Causes • Treatments • Complications Types • Type 1 • Type 2 • Genetic defects – MODY • Gestational • Drugs • Pancreatic disease – – – – – – Tumour Infection Trauma Haemachromatosis CF Surgeons • Endocrinopathies “I used to have non-insulin dependent diabetes mellitus but now I am on insulin. My endocrine doctor says I now have insulin dependent noninsulin dependent diabetes mellitus....” Insulin Resistance Beta cell failure What must I know? • Diagnosis • Types/ Causes • Treatments • Complications Type 1 Insulins • Once Daily • Mixed Insulin • Once Daily and Meal time • Pumps Type 2 Tried, trusted and cheap as chips • Metformin • Gliclazide MR New Drugs • Exenatide • Liraglitide Insulins • Once Daily • Mixed Insulin • Once Daily and Meal time • Pumps What must I know? • Diagnosis • Types/ Causes • Treatments • Complications UKPDS- Type 2 DCCT- Type 1 I’ve learned something today • Diagnosis • Types/ Causes • Treatments • Complications