Less of You To Love A Nutritionist’s Secrets for Healthy Weight Management Neil E. Levin, CCN, DANLA April 2010 Neil E. Levin, CCN, DANLA • Programs Committee Chair and Member of the Board of Directors of the American Nutrition Association®. • Nutrition Education Manager, NOW Foods, Bloomingdale, Illinois © 2010 American Nutrition Association Holistic Diet Principles • TO LOSE WEIGHT, YOU HAVE TO EAT! • TO LOSE WEIGHT, EAT LESS AT EACH MEAL! • TO LOSE WEIGHT, EAT HEALTHY FOOD! • TO LOSE WEIGHT, EAT FAT! • TO LOSE WEIGHT, REDUCE CARBS! Holistic Diet Principles • TO LOSE WEIGHT, YOU HAVE TO EAT! –Fasting slows metabolism –Empty calories don’t satisfy nutritional needs » Protein » Fats » Fiber » Vitamins & Minerals; other nutritional components Holistic Diet Principles • TO LOSE WEIGHT, EAT LESS AT EACH MEAL! –Increase meal count, not calories –Help regulate blood sugar –A small meal can substitute for snacking –Stimulates metabolism if protein is consumed Holistic Diet Principles • TO LOSE WEIGHT, EAT HEALTHY FOOD! –Whole foods promote lean bodies –Whole foods prevent blood sugar spikes –Whole foods provide essential nutrients –Fiber is more filling –Artificial sweeteners can backfire! Holistic Diet Principles • TO LOSE WEIGHT, EAT FAT! –The body needs healthy oils » Essential fats »Omega-3: ALA, EPA, DHA »Omega-6: GLA, AA, CLA » Non-essential fats »Omega-9: stearic acid, oleic acid »Other oily fractions Holistic Diet Principles • TO LOSE WEIGHT, REDUCE CARBS! –Fiber is still fine –Wheat/gluten issues for some –Refined sugars » Conversion to fat » Fuels microbial overgrowths » Raises lipid triglycerides Digestive Support & Enzymes • Plant enzymes work in a wide pH range and begin digesting fats and carbs in the stomach, rather than waiting for pancreatic enzymes to begin work in the intestine • Animal enzymes – HCl-Pepsin work in the stomach to digest minerals and proteins – Pancreatin works in the small intestine to absorb protein, carbs and fats Digestive Support & Enzymes Other Considerations Probiotics (Acidophilus, et al) Depleted by antibiotics & other factors (not a label claim) * From fermented foods that are not subsequently cooked Assist GI function and immunity * Prebiotics (fiber: FOS, Inulin) help maintain an environment friendly to probiotics * Aloe vera Weight Management Products General nutritional support Multiple vitamins with minerals provide essential nutrition and help to balance the diet Most Americans are deficient in at least one essential vitamin or mineral Many of us are deficient in more than one nutrient Reduced nutritional values of modern foods Weight Management Products Anti-enzymes Reduce the breakdown of starch to sugar Phase 2® is an “anti-enzyme” which can reduce the breakdown of starch to sugar. This all-natural bean extract limits the action of alphaamylase, a digestive enzyme. Weight Management Products Appetite Reduction Relora® reduces stress symptoms and can help control appetite and prevent stress-related eating for weight control. Hoodia is a 20:1 South African plant concentrate Slimaluma™ is an alternative to Hoodia Glucomannan fiber relieves constipation and may help to maintain healthy serum lipid levels and satiety (feeling full) Weight Management Products Fibers that bind to fats Chitosan attracts fats better than most other fibers, carrying them out of the body Fiber bonding to bile salts is the body’s primary method of dumping cholesterol Whole grain products provide essential dietary components that enhance our ability to maintain normal weight and metabolism Weight Management Products Limiting the liver's production of fat from carbohydrates Citrimax® helps to limit the liver's production of fat from carbohydrate. Provides HCA, which may reduce the liver’s conversion of carbohydrates into stored fats. Weight Management Products Substances to maintain healthy blood sugar Alpha Lipoic Acid (ALA) improves insulin sensitivity Chromium helps control blood sugar and is a component of Glucose Tolerance Factor. Chromium may also help maintain lean body mass (muscle) during calorie-restricted dieting. Vanadium is another mineral useful for blood sugar control Weight Management Products Substances to help maintain healthy blood sugar levels GlucoFit™ is a source of corosolic acid, which supports healthy glucose metabolism and insulin sensitivity Gymnema sylvestre improves uptake of glucose into cells, may minimize a “sweet tooth” and may be useful for maintaining cholesterol and triglyceride levels Weight Management Products Mild stimulants and thermogenic ingredients that enhance energy production Green Tea Extract for thermogenesis L-Carnitine helps convert fat to energy Pyruvate may enhance weight loss and reduce body fat L-Tyrosine is a precursor or thyroid hormones Weight Management Products Mild stimulants and thermogenic ingredients that enhance energy production 7-Keto® is a metabolite of DHEA that does not affect sex hormones. 7-Keto® enhances the activity of three key fat burning (thermogenic) enzymes to provide a higher metabolic rate during periods of calorie restriction and diet modification. 7-Keto, with a program of diet and exercise, accelerates weight and fat loss by 200% over the same period of time compared to comparable dieting and exercise with placebo. Weight Management Products Fats and other substances that enhance fat metabolism and encourage lean muscle mass CLA boasts numerous studies as to its ability to enhance body composition – specifically lean body mass – when used for long periods of time (typically over a year). Weight Management Products Reduction of cortisol Chronic stress can also result in improper blood sugar metabolism, triggered by the stress hormone cortisol. Relora® reduces stress symptoms to help control appetite and prevent stress-related eating for weight control. Chronic stress is a major contributing factor in overeating. Weight Management Products Acai A Genuine Whole Food; solvent free Brazilian purple berries Freeze-dried; from pulp and skin Antioxidant rich; fresh taste Also contains proteins, fats (as in fresh acai) Supports cardiovascular (nitric oxide), immune, and inflammatory systems Weight Management Products Metabolic Products • CLA maintains lean body composition, with significantly lower weight than controls in long-term experiments. • Green tea and guarana supply natural caffeine and other energizing compounds, plus antioxidants • Chromium is used to regulate fat and sugar metabolism Weight Management Products CLA One study, titled "Efficacy and Safety of One-Year Supplementation with Conjugated linoleic Acid in Moderate Overweight," found that compared to placebo, CLA-supplemented subjects had Body Fat Mass index scores averaging 9% lower than the placebo group and had Lean Body Mass results showing lean muscle mass averaging 2% more than the placebo group. Analyses of blood tests showed no side effects over this one-year period. Weight Management Products CLA CLA plus Guarana reportedly reduces the size and number of fat cells in another report. CLA may also reduce insulin resistance and prevent undesirable cellular changes. Weight Management Products CLA CLA may reduce insulin resistance, so people on blood sugar medications may not need as much of their drugs. Use with caution to avoid an overdose of your blood sugar medication when using this oil. Please notify your physician about your supplement use if you are using any drugs! Gaullier JM, Halse J, Hoye K, Kristiansen K, Fagertun H, Vik H, Gudmundsen O. Conjugated linoleic acid supplementation for 1 y reduces body fat mass in healthy overweight humans. Am. J. Clin. Nutr. 79(6):1118–1125 (2004). Rainer L, Heiss CJ. Conjugated linoleic acid: Health implications and effects on body composition. J. Am. Dietetic Assoc. 104(6):963–968 (2004). O'Shea M. Clarinol(TM) CLA (Conjugated Linoleic Acid): the weight of evidence supports a safe and efficacious product for weight management. Agro Food Industry Hi-Tech 15(4):24–26 (2004). Malpuech-Brugere C, Verboeket-van de Venne WPHG, Mensink RP, Arnal MA, Morio B, Brandolini M, Saebo A, Lassel TS, Chardigny JM, Sebedio JL, Beaufrere B. Effects of two conjugated linoleic acid isomers on body fat mass in overweight humans. Obesity Res. 12(4):591–598 (2004). Weight Management Products Glucose Metabolic Support GlucoFit™ provides corosolic acid to maintain a healthy glucose metabolism Gymnema sylvestre supports blood sugar regulation and supports the pancreas Weight Management Products Chromium (ChromeMate®) Niacin-bound chromium for proper insulin function and normal energy production Promotion of healthy body weight Maintenance of healthy blood sugar and cholesterol levels already within the normal range. Weight Management Products L-Carnitine Shuttles long-chain fatty acids to the cell’s mitochondria to be oxidized and converted into ATP BLOOD SUGAR Excess Blood Sugar Converts to fat Challenges blood sugar controls Reduces insulin sensitivity Reduces immunity to infections Excess Blood Sugar “...people with diabetes who have high blood sugar lose a lot more magnesium in the urine and, as a result, run the risk of magnesium deficiency" Karen Kubena, Ph.D., associate professor of nutrition at Texas A & M University in College Station. Excess Blood Sugar Elevated or normal insulin + Cellular resistance to insulin = Elevated blood glucose Excess Blood Sugar Hypoglycemia: Overreaction to the rise in blood sugar after eating Indicates poorly controlled blood sugar mechanism May lead to insulin resistance Excess Blood Sugar Pre-diabetes Syndrome X Metabolic Syndrome Metabolic Syndrome Syndrome: Definition “run together” A pattern of signs and symptoms Follow a common physiological and metabolic pathway Does not indicate the cause (disease), only recognizes a common pattern Essential part of clinical practice Metabolic Syndrome Sugar Control Nutrients Chromium Alpha Lipoic Acid Corosolic acid (banaba leaf) Vanadium Fiber Omega-3 fats Sweetness Suppressor Gymnema sylvestre Standardized to minimum 25% Gymnemic Acid Ayurvedic herb from India Acts on pancreas to stimulate insulin secretion Sweetness Suppressor Gymnema sylvestre Improves uptake of glucose into cells May block ability to taste “sweet” May be useful for maintaining cholesterol and triglyceride levels Sweetness Suppressor Zinc is a known sweet taste inhibitor, meaning it can be used to suppress the unwanted sweetness of a product SUGAR ALCOHOLS Sweeteners Sugar Alcohols Erythritol Maltitol Mannitol Sorbitol Xylitol Sweeteners Sugar alcohols don’t raise blood sugar as rapidly as sugar does, yet they’re as bulky as sugar. Used “tablespoon - for - tablespoon” to replace sugar Their sweetness may vary Sweeteners Sugar Alcohols FDA-approved health claim: Frequent between-meal consumption of foods high in sugars and starches promotes tooth decay. The sugar alcohols in [name of food] do not promote tooth decay. Sweeteners Sugar Alcohols For FDA-approved health claim the product must be: - Sugar free Sweeteners Sugar Alcohols For FDA-approved health claim: The sugar alcohol must be xylitol, sorbitol, mannitol, maltitol, isomalt, lactitol, hydrogenated starch hydrolysates, hydrogenated glucose syrups, erythritol, or a combination. Sweeteners Sugar Alcohols For FDA-approved health claim: - When a fermentable carbohydrate is present, the food must not lower plaque pH below 5.7. Sweeteners Erythritol Fermented cornstarch Similar to xylitol in flavor, physical characteristics Sweeteners Erythritol Almost non-caloric, nonmetabolized Non-laxative Stronger osmotic antimicrobial than xylitol 70% as sweet as sugar Sweeteners Erythritol “These results suggest that erythritol affects glucose metabolism and reduces lipid peroxidation, thereby improving the damage caused by oxidative stress involved in the pathogenesis of diabetes.” Yokozawa T, Kim HY, Cho EJ. Erythritol attenuates the diabetic oxidative stress through modulating glucose metabolism and lipid peroxidation in streptozotocin-induced diabetic rats. J Agric Food Chem. 2002 Sep 11;50(19):5485-9. Sweeteners Xylitol Osmotic antimicrobial (inhibits bacterial growth) Cooling in mouth 1:1 substitution for sugar in recipes Sweeteners Xylitol Improves bone density, Protects tooth enamel Does not require insulin A laxative in higher amounts Typically 30-50 grams or 15-25 packets Sweeteners Xylitol Can be commercially produced from non-GMO cornhusks, corn cobs and stalks, certain hardwoods (birch and beech), rice, oat, wheat and cotton seed hulls, various nut shells, straw, sugar cane Sweeteners Xylitol Dietary sources containing relatively high quantities of xylitol are plums, raspberries and cauliflower Stevia Stevioside and rebaudioside A are hydrolyzed to steviol by human intestinal microflora References: Cos, P.; Ying, L.; Calomme, M.; Hu, J. P.; Cimanga, K.; Poel, B. V.; Pieters, L.; Vlietinck, A. J.; Berghe, D. V. Structure-activity relationship and classification of flavonoids as inhibitors of xanthine oxidase and superoxide scavengers. J. Nat. Prod. 1998, 61, Hollman, P. C. H.; de Vries, J. H. M.; van Leeuwen, S. D.; Mengelers, M. J. B.; Katan, M. B. Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers. Am. J. Clin. Nutr. 1995, 62, 1276– 1282. Chatsudthipong V, Muanprasat C. Stevioside and related compounds: Therapeutic benefits beyond sweetness. Pharmacol Ther. 2009 Jan;121(1):41-54. Epub 2008 Oct 27. PMID: 19000919 In vitro metabolism of the glycosidic sweeteners, stevia mixture and enzymatically modified stevia in human intestinal microflora. Koyama E, Kitazawa K, Ohori Y, Izawa O, Kakegawa K, Fujino A, Ui M. Food Chem Toxicol. 2003 Mar;41(3):359-74. PMID: 12504168 Stevia Whole Leaf Stevia contains over 100 phytochemical markers including: •Polyphenols •Flavonoids •Caffeic Acid •Sterebins •Austroinulin •Quercetin •Luteolin •Apigenin •Centaureidin (Flavanol) Enzyme Treated Stevia Standard Stevia Enzyme Treated Stevia rebaudiana Herbal effects: May reduce insulin resistance May aid pancreatic function May help to maintain BP already in the normal range May support immunity Stevia rebaudiana (Enzyme Modified) Reference: Chatsudthipong V, Muanprasat C. Stevioside and related compounds: Therapeutic benefits beyond sweetness. Pharmacol Ther. 2009 Jan;121(1):41-54. Epub 2008 Oct 27. PMID: 19000919 Stevia Safety Stevia and steviosides are considered safe Stevia is not toxic to cells No allergic reactions to it seem to exist No significant adverse effects were noted in a 2-year study Non-caloric Does not encourage dental cavities Geuns JM. Stevioside. Phytochemistry. 2003 Nov;64(5):913-21. PMID: 14561506 Yasukawa, K.; Kitanaka, S.; Seo, S. Inhibitory effect of stevioside on tumor promotion by 12-OTetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin. Biol. Pharm. Bull. 2002, 25, 1488-1490. Boonkaewwan C, Toskulkao C, Vongsakul M. Anti-Inflammatory and Immunomodulatory Activities of Stevioside and Its Metabolite Steviol on THP-1 Cells. J Agric Food Chem. 2006 Feb 8;54(3):785-9. PMID: 16448183 Gardana C, Simonetti P, Canzi E, Zanchi R, Pietta P. Metabolism of stevioside and rebaudioside A from Stevia rebaudiana extracts by human microflora. J Agric Food Chem. 2003 Oct 22;51(22):661822. PMID: 14558786