ALLERGIES AND FOOD INTOLERANCES DEFINITIONS • ALLERGEN – a foreign protein or antigen that induces excess production of certain immune system antibodies. Subsequent exposure leads to the allergic response. Can cause a rapid increase in heart rate and difficulty in breathing. House dust mites, pets, pollen insects, moulds, foods and medicines. • Allergy occurs when a person’s immune system reacts to substances in the environment that are harmless for most people • Food Allergy: occur in ATOPIC people – those born with overactive immune systems that produce IgE antibodies to substances in their environment or diet which would normally be harmless. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 2 • FOOD INTOLERANCE – an adverse reaction that does not provoke an allergic reaction or the immune system, but the sensory nerves that trigger a reaction. • FOOD SENSITIVITY – a mild reaction to a substance that may be expressed as a light rash or itching • See www.allergy.org.au and www.allegy.net.au Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 3 Overview Presentation Food Allergy Coeliac Disease Food Intolerance Infantile eczema Fatigue Acute Reactions: •Rash around mouth •Hives/swelling •Vomiting •Breathing difficulty •Anaphylaxis GI: •Bloating •Cramps •Diarrhoea Episodic/recurrent: •Hives/swellings •Stomach/bowel irritation •Headaches/migraine •Fatigue/aches/pains •Mouth ulcers •Sinus congestion/ polyps •Anaemia May be asymptomatic In Children: Irritable behaviour – colic, screaming, disturbed sleep, leg aches & pains ADHD Reflux from birth Eczema itchy rashes Nappy rash Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 4 Food Allergy Coeliac Disease Food Intolerance Age of onset Infants & toddlers Mostly Any age Any age Family Hs Atopic – asthma, eczema, hay fever HLA Gene Association coeliac diabetes, thyroid Commonly IBD hives, headaches, mouth ulcers Reaction immediate, min to 1-2hrs Reproducible Chronic Reproducible Hours – days variable Mechanism Immune IgE antibodies Immune inflammatory T Cells Non immune irritation of nerve endings Food triggers Specific foods proteins Gluten Natural food chemicals Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 5 Food Allergy Coeliac Disease Food intolerance Tests Skin prick test, blood tests (RAST) measure IgE to specific allergens Must be eating gluten: Ab to transglutaminase Small bowel biopsy to confirm Dx. Elimination Diet food chemical challenges Dietary Management Complete avoiance of single foods Gluten free diet – strict Comprehensive dietary modification to maintain a chemical load below reaction threshold Outcome Egg, milk, usually outgrown. Peanut, tree nuts and seafood often persist (70-80%) Life long immune reactivity Bowel pathology and Ab usually return to normal on gluten free diet Life long susceptibility. Variable tolerance Symptoms can come and go. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 6 Symptoms and mechanisms • Allergic reactions to food are quite common and occur more frequently in females than in males. • Food allergies occur most frequently during infancy and young adulthood. Experts estimate that up to about 1% to 2% of adults and up to about 4% to 8% of children are allergic to certain foods. • Occurs in around 1 in 20 children and in about 1 in 100 adults. • Symptoms can include – Nose and/or eyes hay fever, allergic rhinitis/conjuctivitis – Skin – eczema, hives – Lungs asthma Written-by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 7 • Allergic reactions vary not only in the body system affected but also in their duration, ranging from seconds to a few days. A generalised, all-systems reaction is called anaphylactic shock. • This severe allergic response results in lowered blood pressure and respiratory and GI tract distress. • It can be fatal. • Although any food can trigger anaphylactic shock, the moist common culprits are peanuts, tree nuts (walnuts, pecans etc), shellfish, milk, eggs, soybeans, wheat and fish. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 8 • Any reaction that is milder than these distinct allergic ones is referred to as a food sensitivity. • Three types of reactions may occur after ingestion of problem foods by susceptible people: – Classic – itching, reddening of the skin, asthma, swelling, choking, and a runny nose – GI Tract – nausea, vomiting, diarrhoea, intestinal gas, bloating pain, constipation, and indigestion – General – headache, skin reaction, tension and fatigue, tremors and psychological problems Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 9 Halkin,S. 2004, `Prevention of allergic disease in childhood: clinical and epidemiological aspects of primary and secondary allergy prevention’, Pediatric, Allergy and Immunology, vol.15, no.suupl 16, pp.4-5, 9-32) • The development and expression of atopic diseases depends on a complex interaction between genetic factors, environmental exposure to allergens and non-specific adjuvant factors, such as tobacco smoke, air pollution and infections. • Preventive measures may include both exposure to allergens and adjuvant risk/protective factors and pharmacological treatment. • The combination of atopic heredity and elevated cord blood IgE resulted in the best predictive discrimination as regards development of allergic disease. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 10 • In symptomatic children allergen-specific treatment may influence both the symptoms and the prognosis. – Allergen avoidance can reduce the need for pharmacological treatment, – SIT may have the potential for preventing the development of asthma in children with allergic rhinoconjunctivitis. – It may be possible to interfere with the natural course of allergic diseases. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 11 (Lance,F., Micheau,P., Marchac,V., Scheinmann,P. 2003, `Food allergy and asthma in children’, Revue de Pneumologie CLinique, vol.59, no.2 pt 1, pp. 109-13) • The links between food allergy and asthma are becoming more clear. • The association of food allergy and asthma in the same child is unusual (less than 10% in atopic subjects). • This association is however a sign of gravity leading to more severe manifestations of food allergy in asthmatic children. • Compared with the non-asthmatic child, the asthmatic child has a 14-fold higher risk of developing a severe allergic reaction to the ingestion of food. The most commonly cited foods are fruits with a rind, cow's milk and, of course, nuts. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 12 COELIAC DISEASE Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 13 An Autoimmune Disease • The body makes antibodies against the cells of the SI, in response to gluten ‘contaminating’ the cells of the small intestine. • Results in the villi become inflamed and flattened which results in decreased ability to digest foods and absorb nutrients from the food. • The resulting villi atrophy can lead to nutrition deficiencies for all nutrients, but of particular concern is Iron, Calcium, Magnesium, protein. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 14 Symptoms or can be Asymptomatic • Fatigue, weakness and lethargy • Anaemia • Flatulence and abdominal distension • Diarrhoea and/or Constipation • Cramping and bloating • Nausea and vomiting • Weight loss/gain Less common but possible: • Easy bruising • Recurrent mouth ulcers and/or swelling of mouth or tongue • Miscarriage and infertility Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 15 • • • • • Low Ca, vitamin and other mineral deficiencies Skin rashes including dermatitis herpetiformis Dental defects Altered mental alertness Bone and joint pains In children • As above, and • Steatorrhea • Poor weight gain • Weight loss in older children, • Delayed growth or delayed puberty Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 16 Possible Co-Morbidities • Hair loss • Dental enamel defects • Infertility and recurrent miscarriage • Lethargy • Mouth ulcers • Osteoporosis • Reproductive issues • Changes to gut integrity that may or may not resolve with gluten avoidance. Other autoimmune diseases • A-1 atropic gastritis • Addison disease • Colitis • Congenital heart defects • Dermatitis herpetiformis • Don’s syndrome • Hypo-splenia • IgA nephropathy • Liver enzyme disturbance Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 17 • Neurological incl neuropathies, ataxia, memory impairment, migraines, epilepsy or muscular stiffness • Primary biliaary cirrhosis • Psoriasis • Sarcoidosis • Serum IgA deficiency • Sjorgren syndrome • Thyroid hypo or hyper • Turner syndrome • type 1 diabetes • Williams syndrome • Small but possible Ca risk with untreated celiac disease Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 18 Food Intolerances • Food intolerances are adverse reactions to chemicals in food that do not involves allergic mechanisms. • It is nerve/sensory reaction that causes the symptom expression. • Generally, larger amounts of the offending food are required to produce symptoms of intolerance than to trigger allergic symptoms. • Symptoms are person specific, and can change with different chemicals. Just because it is natural, doesn’t Mean Your body will like it. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 19 • Common symptoms are – – – – Recurrent hives and swellings. Stomach and bowel irritation Headaches. Some people have flue like • aches & Pains, • Unusually tired, run down or moody – Children can be irritable, restless, with aggravated behaviour such as ADHD. – Babies colicky irritable behaviour, reflux, loose stools, eczema and or nappy rashes. • Symptoms can depend on a number of factors include predisposition to sensitivity, dose and frequency of consuming those chemicals. Because many foods naturally contain a mix of irritants, than the type of food can push an individual over the edge. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 20 Foods containing chemicals/Chemical Load Additive Effect Threshold/ Symptoms juice banana cheese Time/dose Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 21 • The additive effect of chemicals over a period of time, either single or mixed can over a period of time push a person over their threshold, and symptoms occur. • Because of the mixed chemicals in food, and the accumulative effect they can have in the body, it is important to determine which chemical it is and the individual’s tolerance level to it. • The tolerance level can also change with stress, circumstances and avoidance of offending foods for a long period of time. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 22 Common causes Certain foods such as red wine, tomatoes, pineapples that cause physiological effects such as a change in blood pressure Synthetic compounds such as sulphates, food colouring agents and MSG A reaction to Tartrazine, a food colouring additive Food contaminants including antibiotics, chemicals or even insect parts Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 23 Tyramine, a derivative of the amino acid tyrosine, is commonly found in aged foods such as cheeses and red wine, can cause high blood pressure in people taking MAOI’s for depression or mental disorders Toxic contaminants such as salmonella bacteria or clostridium botulinum or other food borne microbes Digestive enzyme deficiency e.g. lactase Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 24 Common Foods It is very possible to be sensitive to more than one chemical And include: – Natural food chemicals salicylates, amines, glutamate, – Food additives. • Considering all plants and animals must protect themselves from a mirage of insects, moulds, yeasts it is very possible for a food to contain a mix of these naturally occurring chemicals at any one time. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 25 Salicylates plant chemicals naturally found in • many fruits & vegetables, • nuts, • herbs and spices, • Jams & honey, • yeast extracts, • tea, coffee, juices beer and wine. • Natural flavourings used in foods, • drinks • and liquid medications. • scents in perfumes, • toiletries, • cleaning products, washing powders and • essential oils. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 26 Amines • From protein breakdown • Levels increase in protein foods as they age or mature – meats, fish and cheese • and fruits as they ripen – Bananas, tomato, avocado, pawpaw, olives High levels are in • sauces, fruit juices, chocolate • Flavoured spreads – nuts and seed pastes & jams • Fermented products beer, wine and yeast extracts. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 27 Other Food Chemicals Glutamate • An AA of protein found naturally in most foods. • In free form it enhances the flavour of food. • Cheese, tomato, mushrooms, stock cubes, soy sauce, meat & yeast extracts. Lactose • Sugar in milk products. • If reactive to chocolate, hard cheese, and cakes. It is likely not lactose, but other chemicals in these foods. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 28 Fructose, Fructans and Prebiotics • Found if fruits and normally able to be absorbed across the SI. • Illness, SI damage, antibiotics and stress can reduce the digestion of fructose in the SI and alter the bacterial balance of the LI. • Gut bacteria ferment the fructose and non digestible fibres causing swelling and irritation to the gut. • This can also cause gastro like reactions causing discomfort, and flatulence. • Of particular interest for clients with IBS Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 29 Food Additives • Used to enhance flavour, appearance, maintain freshness and increase shelf life of foods. • The body can not determine if it is natural or artificial in processed foods as they are chemically similar or identical. • People sensitive to natural chemicals, are usually sensitive to one or more common additives of preservatives, artificial colour & flavourings. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 30 – Sulphites, which are added to food and beverages as antioxidants, cause flushing, spasm of the airways, and a loss of blood pressure in susceptible people. Wine, dehydrated potatoes. Dried fruits, gravy, soup mixes, and restaurant salad greens commonly contain sulphites. – A reaction to MSG may include an increase in blood pressure, numbness, sweating, vomiting, headaches and facial pressure. MSG is commonly found in Chinese foods and many processed foods e.g. soups Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 31 • Tyramine, a derivative of the amino acid tyrosine, is commonly found in “aged” foods, such as cheeses and red wines. This natural food constituent can cause high blood pressure in people taking monoamine-oxidase inhibitor medications, which may be prescribed for mental depression. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 32 Organic Foods? • By not using pesticides and other chemicals to ward of pests it forces the plant to increase its own production of pest control chemicals, in particular salicalytes. • For people who are sensitive, this is a point to be aware of. They might be getting ‘better’ quality of nutrient richness, with an increased natural chemical load. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 33 Diagnosis Pathway Elimination Diet Symptom Free No Response Normal Diet/FODMAP 2- 6 Weeks DBPC chemical Challenge 5 well days Open Food Challenge Individualised Diet 6-8 weeks Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 34 Irritable Bowel Syndrome • Irritable bowel syndrome (IBS) & chronic inflammatory bowel disease (IBD) is a difficult but an important challenge to recognize and treat. • Chronic inflammation in IBD, IBS symptoms occur with increased frequency and severity, secondary to increased hypersensitivity to foods and beverages that stimulate the gastrointestinal tract. • The adverse effects of many foods and beverages are amount dependent and can be delayed, additive, and cumulative. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 35 • The specific types of foods and beverages that can induce IBS symptoms include – – – – – – – – – – – – – milk and milk containing products – lactose and proteins caffeine containing products alcoholic beverages Fruits and fruit juices Spices and seasonings diet beverages, diet foods, diet candies, diet gum fast foods, fried foods and fatty foods Condiments, gravies, spaghetti sauce, multigrain breads, sourdough breads, bagels Salads and salad dressings Vegetables, beans, high fibre red meats, stews, nuts, popcorn cookies, crackers, pretzels, cakes, and pies. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 36 • The types of foods and beverages that are better tolerated include – water – Rice, plain pasta or noodles – baked or boiled potatoes – white breads – plain fish, chicken, turkey, or ham – eggs – dry cereals – soy or rice based products – peas – Applesauce, cantaloupe, watermelon, fruit cocktail – margarine – Jams, jellies, and peanut butter. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 37 Possible Causes • Immune system imbalance • Use of antibiotics causing dysbiosis • Western eating plan that disrupts the chemical balance of the gut • Low stomach acid – reduced digestion of proteins and nutrient activation: minerals and B12 • Medications • Irritants in foods • Stress, hormone imbalance • Slow transit time Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 38 FODMAPs • Fermentable • Oligosaccharides - Fructans, Galacto-oligosaccharides (GOS) • • • • Disaccharides Monosaccharide And Polyols Lactose Fructose in excess of glucose sorbitol manitol These are all CHO based foods with sorbitol and manitol being sugar alcohols. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 39 Mechanism of FODMAPs • Fodmap compounds are poorly absorbed in the small intestine and enter the large intestine • The bacteria digests and ferments these CHO and Sugar alcohols producing gas and other essential acids. • It also causes osmolarity changes, which draws water into the colon. This and the increased gas, leads to dissention of the colon wall, irritating the sensory nerves and increases motility – diarrhoea and faecal urgency. • Pain, bloating, distension, wind, constipation +/diarrhoea can occur. • Via the sensory Hypothalamus-Pituitary-Adrenal Axis, triggers secondary responses which can perpetuate the problem Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 40 NOW WHAT??? Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 41 Determine Which Tx Pathway!! • Considering the overlapping presentation of symptoms, and foods it is vital to determine which is the pathway of the symptoms the body is following. • If this is inaccurate than the condition may not resolve easily or at all. • The condition may not resolve even if you and client have correctly determined the pathway and treatment modality if the person is hypersensitive, or if they continue to consume foods that are an irritant to them. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 42 Shared Symptoms, Different Reaction IgE Food Allergy Coeliac Disease Food Intolerance T Cell Mediated Non-Immunological Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 43 Assessment strategy As part of a complete history taking, you need to target: • History targets Includes but not limited to – description of symptoms, – time between food ingestion and onset of symptoms, – duration of symptoms, – most recent allergic episode, – quantity of food required to produce reaction, – suspected foods, – and allergic diseases in other family members – History of other autoimmune diseases. – Complete Family Sensitivity History & Total Body Load Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 44 Physical • Physical examination – Look for signs of an allergic reaction (rash, itching, intestinal bloating, sinusitis, etc) – Functional bowel symptoms • Bloating, pain, sensitivities. • Urgency of elimination • Irritable bowel like symptoms. • Smell, texture color etc of motions • BMI • Weight change and %; malnutrition scale • Growth charts for children Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 45 Patient presents with symptoms and food history Other Diagnosis Assess Alarm Features Appropriate Treatment Coeliac Testing and other Testing Functional Bowel Disorder no RPAH Elimination Diet yes Breath hydrogen & methane with fructose and lactose to assess absorptive capacity Restriction of lactose if lactose malabsorption present Complete FODMAP restriction Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 46 Pathology Tests Allergy • RAST Test to identify elevated IgE antibodies. Does not conclude allergy . • Allergy - testing under supervised conditions if at risk of anaphylactic reaction. Coeliac testing • If currently eating gluten, request pathology for Coeliac disease either Ab anti-transmutase or Gene test - HLA DQ2/DQ8 tissue typing for family risk. Small bowel biopsy • If not eating gluten, encourage to do so and follow up with tests. • If –ve, consider intolerance and follow elimination diet or if bowel symptoms are predominant consider FODMAP. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 47 Other tests of value include • Liver function, Serum Ferritin, Ca2+, B12, Folate, albumin. • BGL; GTT; immune function • Hydrogen, methane breath testing. CAM tests • Functional liver test • Stool anaylsis Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 48 Assessment Phase • Based on the information gleaned, pathology collected and interpreted a change in eating plan will result. Which one will be determined by the diagnosis or in some cases no diagnosis. • • Be sure all possible pathological causes are cleared before embarking on a massive treatment plan. Undiagnosed, serious conditions can manifest if left untreated. • If the client chooses not to follow investigative processes, then consider referring them on, signing a waiver form, and be sure you have discussed the possible outcomes of not following this pathway first. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 49 Treatment of food allergies • Refer back to the allergy clinic or under medical supervision to complete tests. • Once allergens are identified, ensure the client is meeting nutritional needs while Avoiding known allergen/s • Educate the client how to read labels and the common names for the allergen so they can avoid accidental exposure. • Be aware of: • Allergens can cross the placenta during pregnancy and can be secreted in the breast milk • 80% of children with food allergies outgrow them before 3 years of age. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 50 • After 3 years of age, 33% outgrow them in the next 3 years. • For others, it will most probably be lifetime • Perform regular controlled food challenges (Jamison p.147) Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 51 Coeliac Disease • Must avoid all gluten containing products which include whole grains and their products from Wheat; Rye; Barley and for some, Oats. This interprets to: • Breakfast cereals, breads and toast; • Muslie bars, grained bars; • Cakes, pastries, biscuits made from the above flours • Pasta, in most forms, cous cous, semolina, spelt, triticale, wheatgerm, bran & meal • Wheatened cornflour, modified starch, • Malt and extracts, Malt vinegar • May contain – beverage whitener, dextrin, maltodextrin thickeners 1400-1450 Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 52 • From their food diary, show them their sources of gluten, offer the alternatives; • Grains such as rice, polenta, sago, sorghum, soy • Baked goods using – Arrowroot, buckwheat, corn maize, millet, pollenta – Rice, sago, soy, tapioca • Fibre from psyllium, LSA, slippery elm, and ‘greens’ if additional is required. • There are plenty of products in the supermarket, and also in the shops that can meet most needs. • Recipe books are also plentiful to help a person make things from scratch. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 53 Food Intolerance Follow the principles of the RPAH elimination diet which include: • Determine the severity of the reactions and negotiate how strict the elimination period will need to be. • Individuation will be guided by • Clinical pattern – frequency and severity etc • IBS – exclude milk, wheat, so and windy foods • Personal preference – strict, moderate, simple • Personal circumstances. • Need to include only those foods indicated in the charts – RPAH protocol Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 54 Challenge Phase • When the client is symptom free for at least 5 days reintroduce a food that contains only that chemical you have chosen to test. Keep in mind the following: • Do not give a client a known allergen such as wheat, milk, seafood, nuts etc or if they have had a severe reaction in the past such as throat or tongue swelling or difficult to breathe • How much to eat – Reactions are dose dependent – Eat as much as possible spread over the day – Do not use known trigger foods identified during history Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 55 • How long to continue? – Up to 7 days for milk, wheat, soy, salicylate, amines – Up to 3 days for msg, preservatives colours • Children – May not be able to eat the amounts recommended – Give them as much as possible – Continue for 7-14 days unless symptoms develop • Going onto the next challenge – – – – Beware of refractory period (2-3) days 3 full days in a row symptom free Be patient, do not rush challenges If uncertain repeat the challenge 2-3 times. • For each challenge monitor and record all changes to body and mind. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 56 Cows Milk Challenge 7 days • Choose milk from drinks list • Build up to 3 cups of cow’s milk/day over a day or two • If no reaction after 7 days, – You can leave milk and low chemical dairy products in your diet during other challenges. Do not give a client cows milk if • known allergy to milk, • or if they have had a severe reaction in the past such as throat or tongue swelling or difficult to breathe Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 57 Soy Drink 7 days • Choose soy drinks for the list provided • Build up to 3 cups of soy drink per day over a day or two • If there is no reaction after 7 days, you can leave soy drink and low chemical soy products in your diet while you proceed with the other challenges. Do not give a client soy milk if • known allergy to soy, • or if they have had a severe reaction in the past such as throat or tongue swelling or difficult to breathe Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 58 Wheat 7 days • Choose from the list provided • Eat at least – 1 cup plain cooked pasta per day And – 12 plain water crackers (antioxidant free)/day • If there is no reaction after 3days, add – 4 slices of bread (no preservatives or vinegar) • If there is no reaction after 7 days, you can keep low chemical wheat products in your diet while you proceed with the other challenges. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 59 Natural Salicylates 7days • Eat at least 6 serves per day, chosen from different foods in any combination • Fruit – 1 large granny smith apple* – ¼-1/2 rockmelon * – 1 large slice watermelon* • Vegetables – – – – 6-8 asparagus spears ½-1 cucumber 1 cup pumpkin 1 cup sweet potato 1 medium zucchini 1 cup carrot Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 60 Cont. • Sweets – 1 Table spoon honey* – 10 pepp-o-mints life savers • Spices – 1 teaspoon curry powder • Drinks – 150ml apple juice unpreserved – 1 cup strong tea – 1 cup peppermint tea • * foods containing Fructose and Salicylate • In patients with IBS test response to fructose first – mango • If fructose causes a reaction, limit the intake of these foods during the salicylate challenge Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 61 Natural Amines 7 days • Eat at least – 2-3 large ripe bananas – 60-120g plain, dark chocolate • In addition, choose freely from – – – – – – – Cocoa powder and drinking chocolate, Pawpaw Pork (not ham or preserved meats) Salmon canned Sardines canned Tuna canned If milk is tolerated, 60-120g mild yellow cheese Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 62 Glutamate 3days • MSG 621 • If amines are tolerated, – 4 Tablespoons of soy sauce mixed into rice or meatballs – Parmesan cheese sprinkled liberally (if milk is tolerated) • If salicylates are tolerated – 500ml chicken noodle packet soup • If amines and salicylates are not tolerated – Chicken salt on preserved chips. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 63 Food Additives 3days • Propionate 280-283 – – – – 4 slices of bread containing these. 3 English muffins 3 crumpets 2 bake at home rolls • BHA/BHT 310-312, 319-321 – 2 small macdonold fries • Nitrite 249-252 – 4 slices of bacon Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 64 cont • Benzoate 210-218 – Sprite • Sorbate 200-203 – Spreads and dips • Sulphate 220-228 – Preserved foods using these • Colourings 102, 107, 122-129, 131-132, 142, 151, 154-155 – Musk sticks, cordial, food colouring Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 65 FODMAPS Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 66 Challenge Procedure • Restrict known or suspected mal-absorbed FODMAPs until adequate symptom control is achieved and maintained, appro 6-8 weeks. • Reintroduce foods in controlled amounts to best balance food restriction with symptoms • Keep in mind that some are partly absorbed – Fructose, – Lactose – Polyols • Some are not absorbed in everyone – Fructans – GOS Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 67 Steps • • • • • Initially use foods that contain only one FODMAP Eat challenge food at least twice during the test week Use the same food and quantity for the week Monitoring symptom response in diary may be useful You may then like to reintroduce small serves of foods containing more than one FODMAP Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 68 If the client is symptom free • Gradually increase the number of foods that contain the FODMAp you are challenging, and continue to assess response Or • Maintain the amount and type of food you have challenged and then continue to the next FODMAP challenge. Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 69 If client is getting symptoms • Wait until symptom free, reduce the serving size to half and challenge again or • Assume the food is a problem food – Severe symptoms during a food challenge they most likely have a very sensitive irritable bowel triggered by that particular food and will likely have to continue restriction Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 70 Other points of interest • Problem foods – It is likely the client does not have to omit the FODMAP completely, the dose is of value. – Try another food from within the same FODMAP group – Rechallenge after a period of time the body may heal or adjust – Relax on the restriction when eating out and allow informed eating choices ie symptoms vs the social value of the outing • Benefit of challenging is it opens up the food choices and they don’t need to over restrict, – Mininises deficiency and food boredom – Allows pleasure. Chocolate cake Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 71 cont • Restrictive diets, even well planned ones run the risk of nutritional inadequacy • Important to include as much variety with in the tolerated foods while still controlling symptoms • Ensure any food or food type is replaced Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 72 Order of Challenge • Mannitol – ½ cup mushrooms – 1/3 cup cauliflower • Sorbitol – 2 fresh apricots or 4 dried halves or – 1 medium nectarine or – 2 peices sugar free chewing gum (artificially sweetened with sorbitol Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 73 • Lactose if suspected – ½ cup low fat milk or – 200g tub yoghurt • Suspected fructose – 1 cheek of mango or – 3 tsp honey • Suspected wheat fructans – 2 slices wholemeal bread • Garlic and leek fructans – 1 clove garlic – ½ leak both green and white • Onion fructans – ¼ cup onion or – For very cautious people, suggest cook with onion and not eating it. – Don’t restrict onion when eating out. • GOS – All legumes – Most important for vegetarians – ½ cup canned and drained legumes Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 74 For All Situations • Education must be given in relation to – Adequate kj and nutrients while on the elimination and challenge phase of the protocol – Reassure the client what is happening. – The know foods that carry the suspected and then confirmed chemical or compound. • how to recognise the confirmed chemical or compound when eating out, shopping for food. • Strategies of how to minimise social difficulties including parties, eating out, travelling • Encourage cooking from scratch as most of the offending chemicals and compounds are in processed/packaged foods Written by leah Marmulla for use by AoCH 2011. use without written permission prohibited. 75