Herb Board Review Robert Hayden, AP, MSOM Basic Concepts of Chinese Herbal Medicine Thermal Properties (Qi) • Hot • Warm • Neutral • Cool • Cold TASTES (Wei) • Acrid (pungent, spicy) - disperses, moves, effuses sweat • Sour - contracts, tightens, astringes • Salty - moistens, softens and descends • Sweet - tonifies, moistens, harmonizes • Bitter - drains and dries • Bland - leaches out Dampness and promotes urination • Astringent - astringes • Aromatic - penetrates turbidity • Specific tastes often correspond to classes of chemical compounds. • Acids, which produce free hydrogen ions, are detected by the presence of a sour taste, and the strength of the acidity is roughly proportional to the intensity of the perception of sour. • Metal salts containing sodium and potassium ions are detected as a salty taste. • Alkaloids, some of which are highly toxic, are generally bitter; this is why we have a natural aversion to bitter tasting plants as foods. • Terpenes and essential oils usually create an acrid or spicy taste. • Sugars, polysaccharides and glycosides are detected as a sweet taste. • All the basic structural and energyproducing compounds of the body, including sugars and starches, fats, and proteins are sweet to taste, and sometimes bland. • It is for this reason most tonics are considered to be sweet. • Sour, salty, astringent, bitter, and acrid, are normally present in the diet only in small quantities of the corresponding chemical constituents, but their importance lies in their ability to potently alter body functions. Herbs which guide into specific Organs or Meridians • • • • • • Heart Rz Coptidis (Huang Lian); Hb Asari cum Radice (Xi Xin) Small Intestine Rz et Rx Ligustici Sinensis (Gao Ben); Cx Phellodendri (Huang Bai) • Kidneys • Rx Duhuo (Du Huo); • Rx Anemarrhenae (Zhi Mu); • Cx Cinnamomi (Rou Gui); • Hb Asari cum Radice (Xi Xin) • Urinary Bladder • Rz et Rx Notopterygii (Qiang Huo) • Lungs • Rx Platycodi (Jie Geng); • Rz Cimicifugae (Sheng Ma); • Hb Allii (Cong Bai); • Rx Angelicae Dahuricae (Bai Zhi) • Large Intestine • Rx Angelicae Dahuricae (Bai Zhi); • Rz Cimicifugae (Sheng Ma); • Gypsum (Shi Gao) • Spleen • Rz Cimicifugae (Sheng Ma); • Rz Atractylodis (Cang Zhu); • Rx Puerariae (Ge Gen); • Rx Paeoniae Lactiflorae (Bai Shao) • Stomach • Rx Angelicae Dahuricae (Bai Zhi); • Rz Cimicifugae (Sheng Ma); • Gypsum (Shi Gao); • Rx Puerariae (Ge Gen) • Gall Bladder • Rx Bupleuri (Chai Hu); • Pc Citri Reticulatae Viride (Qing Pi) • Liver • Pc Citri Reticulatae Viride (Qing Pi); • Fr Evodiae (Wu Zhu Yu); • Rx Ligusitic Wallichi (Chuan Xiong); • Rx Bupleuri (Chai Hu) • Triple Burner • Fr Forsythiae (Lian Qiao); • Rx Bupleuri (Chai Hu); • Upper Burner: Cx Lycii Radicis (Di Gu Pi); • Middle Burner: Pc Citri Reticulatae Viride (Qing Pi); • Lower Burner: Rx Aconiti Carmichaeli Praeparata (Fu Zi) PROCESSING OF HERBS • Cleaning • Pulverizing • Slicing • Washing • Soaking Heat Preparation • • • Dry-Frying (chao) Dries herbs for storage and also increases Middle-Jiao strengthening effects With salt = directs actions to Kidneys, nourishes Yin • Liquid-Frying (zhi) • with honey = tonifying & moistening effects • • • with vinegar = analgesic, astringent, bloodinvigorating, toxicity-relieving effects with wine = clears channels, expels wind, alleviates pain with ginger juice = protects stomach, stops vomiting • Calcining (duan) - makes shells and minerals easier to pulverize • Quick-frying (pao) - reduces toxicity or harshness • Dry-curing/Baking (hong/bei) - mainly to dry flowers or insects • Other methods: • Steaming • Boiling • Quenching • Simmering Preparing to Decoct • • • • Decoct First: Toxic substances: Chuan Wu, Fu Zi, Cao Wu Shells & Minerals: Shi Jue Ming, Long Gu, Mu Li, Ci Shi, Zhen Zhu, Dai Zhe Shi, Gui Ban, Bie Jia, Shi Gao Other: Shui Niu Jiao, Si Gua Luo • • Add Near End: Bo He, Mu Xiang, Sha Ren, Bai Dou Kou, Qing Hao (all aromatics); Da Huang (to purge) • Wrap in gauze: • Xuan Fu Hua, Che Qian Zi, Hua Shi, Qing Dai • Decoct Separately: • Ren Shen, Xi Yang Shen, Lu Rong • Dissolve In Strained Decoction • E Jiao, Yi Tang • Take With Strained Decoction • Chuan Bei Mu, San Qi, Niu Huang, Zhu Sha, Zhu Li Types of Administration • • • • • Water Decoctions (tang) - most common method Tang implies decoction is taken warm; if it is to be taken at room temperature, it is called Yin (e.g.: Zuo Gui Yin) Most active ingredients in Chinese Formulas are best extracted in water -- especially tonics Ingredients can be tailored to each patient (vs pills) Long shelf life of intact herbs, especially roots & barks (vs powders) • • Powders (san) - require less preparation time (no soaking) and less cooking time (increased surface area means active ingredients are extracted quickly); quality degrades quickly, short shelf life Pills (wan) or tablets (pian) - easiest to administer, high compliance; disadvantage is that ingredients are fixed by manufacturer, so can not be customized • Other internal methods: • Medicinal wines, Congees, Syrups • External • Ointments, Plasters, Liniments, Washes, Soaks Herb Combining • Traditional theory differentiates six principles involved in the combining of two herbs: mutual accentuation, mutual enhancement, mutual counteraction, mutual suppression, mutual antagonism, and mutual incompatibility. • • Mutual accentuation occurs whenever two substances with similar functions are combined; in cases where the disharmony requires emphasis of a certain type of action, rather than increase the dosage of one herb beyond the recommended maximum, another herb with similar functions is added. The combination of Rx Scutellariae (Huang Qin) and Rz Coptidis (Huang Lian) to strongly clear Damp Heat would be one example. • • • Mutual enhancement may result when two substances with slightly different but related functions are combined. An example would be the combination of Rz Atractylodis Macrocephalae (Bai Zhu) with Poria (Fu Ling) to strengthen the Spleen Qi and drain Dampness. Both herbs possess both functions to a certain degree, but Fu Ling emphasizes draining Dampness more, and Bai Zhu emphasizes strengthening the Spleen. • • • • Mutual counteraction and mutual suppression are the reduction of toxicity or side effects of one herb by combining it with another. Mutual suppression describes interactions that actively neutralize toxicity, whereas mutual counteraction refers to interactions where toxicity is still present but whose effects are minimized. Common example: using Rz Zingiberis Recens (Sheng Jiang) to reduce the toxicity of Rz Pinelliae (Ban Xia). Rx Glycyrrhizae (Gan Cao) reduces the harshness of many herbs and "smoothes out the rough edges" of formulas. • • Mutual antagonism occurs when two substances reduce or neutralize each other's beneficial effects. Mutual incompatibility occurs when two substances interact to create toxicity not present in either taken separately. Prohibited herb combinations 19 Antagonisms & 18 Incompatibilities • • Mutually antagonistic substance combinations are to be avoided, not necessarily because of dangerous interactions, but because the valuable properties of the substances may be diminished by such combinations. Certain of these combinations consist of substances that are highly toxic individually, and are listed here only because the data appears in the traditional literature. • • • • • Sulphur (Liu Huang) antagonizes Sal Glauberis (Po Xiao) Hydrargyrum (Shui Yin) antagonizes Arsenicum (Pi Shuang) Rx Euphorbiae (Lang Du) antagonizes Lithargyrum (Mi Tou Seng) S Tigli (Ba Dou) antagonizes S Pharbitidis (Qian Niu Zi) Nitrum (Ya Xiao) antagonizes Rz Sparganii (San Leng) • • • • Fl Caryophilli (Ding Xiang) antagonizes Curcumae (Yu Jin) Tuber Rx Aconiti (Wu Tou) antagonizes Cornu Rhinoceri (Xi Jiao) Rx Ginseng (Ren Shen) antagonizes Excrementum Trogopterori (Wu Ling Zhi) Cx Cinnamomi (Rou Gui) antagonizes Halloysitum Rubrum (Chi Shi Zhi) • Mutually incompatible substances that are prohibited for use in combination because of possibly dangerous, toxic or otherwise undesirable side-effects. • Rx Glycyrrhizae (Gan Cao) • incompatible with: • Rx Euphorbiae Kansui (Gan Sui) • Rx Euphorbiae seu Knoxiae (Da Ji) • Flos Daphnes Genkwa (Yuan Hua) • Hb Sargassi (Hai Zao) • Rx Aconiti (all types - Wu Tou; Fu Zi) • incompatible with: • Bulbus Fritillariae (Bei Mu) • Fr Trichosanthis (Gua Lou) • Rz Pinelliae (Ban Xia) • Rz Ampelopsis (Bai Lian) • Rz Bletillae (Bai Ji) • Rz et Rx Veratri (Li Lu) • incompatible with: • Rx Ginseng (Ren Shen) • Rx Glehniae (Sha Shen) • Rx Salviae Miltiorrhizae (Dan Shen) • Rx Sophorae (Ku Shen) • Hb Asari cum Radice (Xi Xin) • Rx Paeoniae Lactiflorae (Bai Shao) Materia Medica Review Herbs that Release the Exterior Introduction to the Category Herbs that Release the Exterior • • • • Used for Wind-Cold (Taiyang stage), or Wind-Heat (Wei level) invading Exterior. Typically acute, but may also use for Exterior components of chronic disease. Primarily act by diaphoresis (promote sweating). Acrid tastes scatter and disperse; relatively light herbs "float" to the surface. • Warm Acrid herbs generally either enter LU & UB, or LU & ST or SP. • LU - regulating the WEI Qi, governs Exterior. • UB - target head/neck • ST/SP - digestive upsets w/ External Evils. • Cool Acrid herbs enter LU & LR. • LR - red, itchy eyes; • Wind-Heat + Blood Heat rashes (LR stores Blood). Warm Acrid Release Exterior • Ma Huang - Ephedra / Hb Ephedrae • Warm, acrid, bitter • • • LU, UB A&I: Wind-Cold Exterior XS. Wheezing. Bi pain. Edema due to Wind-Cold. Cautions: Causes heavy sweating. Caution in deficiency sweating or wheezing, HTN, insomnia Dose: 3-9 g • Gui Zhi - Cinnamon Twig / Rm Cinnamomi • Warm, acrid, sweet • • • LU, UB, H A&I: Wind-Cold Exterior Deficiency. Bi pain limbs & shoulders. Chest pain due to HT Yang Def. Ab pain, masses due to cold & blood stasis. C&C: Contraindicated in warm febrile disease, Yin def + heat. Caution in pregnancy 3-15 g • Zi Su Ye - Perilla Leaf / Fm Perillae • Warm, acrid, aromatic • LU, SP A&I: Wind-Cold. Moves qi in chest & stomach: nausea, vomiting, morning sickness, seafood poisoning. • C&C: Do not boil long time • 3-9 g • Jing Jie - Schizonepeta / Hb Schizonepetae • Sl. warm, acrid, aromatic • LU, LR A&I: Wind-Cold OR Wind-Heat. Vents wind from blood: skin eruption, itching. • Char to stop bleeding. • 3-9 g • Fang Feng - Ledebouriella / Rx Ledebouriellae • Warm, acrid, sweet • • • LR, UB, SP A&I: Wind-Cold. Wind-Damp Bi pain. Spasms due to exterior Wind C&C: Spasms due to blood deficiency. Contraindicated in yin def heat 3-9 g • Qiang Huo - Notopterygium / Rz + Rx Notopterygii • Warm, acrid, bitter, aromatic • • • K, UB A&I: Wind-Cold. Wind-Cold-Damp Bi pain, esp upper body. Guides to Taiyang, Du channels: headache C&C: Contraindicated in pain due to blood deficiency or yin deficiency 3-9 g • Bai Zhi - Dahurian Angelica / Rx Angelicae Dahuricae • Warm, acrid • • • LU, ST A&I: Wind-Cold. Early-stage swelling w/pus. Sinus pain, HA in Yangming channels. C&C: Contraindicated in yin deficiency, late-stage swelling 3-9 g • Xi Xin - Asarum / Hb Asari • Warm, acrid • • • LU, K A&I: Wind-Cold. Wind-Cold-Damp Bi pain. Warms LU: cold phlegm. Nasal obstruction, headache. C&C: Contraindicated in blood deficiency or yin deficiency. NEPHROTOXIC. Use low dose. 1-3 g • Sheng Jiang - Fresh Ginger / Rz Zingiberis recens • Warm, acrid • LU, SP, ST A&I: Wind-Cold. Warms middle & stops vomiting. Warms LU. Detoxifies other herbs. • C&C: Contraindicated in yin deficiency heat • 3-9 g • Xin Yi Hua - Magnolia Flower / Fl Magnoliae • Warm, acrid • • • LU, ST A&I: Wind-Cold nasal obstruction (or any type nasal obstruction depending on how combined) C&C: Caution: Pregnancy. OD: red eyes, dizziness. Boil in cheesecloth or coffee filter. 3-9 g Cool Acrid Release Exterior • Bo He - Mint / Hb Menthae • cool, acrid, aromatic LU, LR • • • A&I: Wind-heat, clears head and eyes. Moves liver Qi. Vents rashes C&C: Not for Def Heat. May reduce lactation. Not to be boiled more than five minutes. 1.5-6 g • Niu Bang Zi - Arctium Fruit / Fr Arctii • cold, acrid, bitter • LU, ST A&I: Wind-heat sore throat. Releases toxins & vents rashes. Moistens intestine • C&C: Contraindicated in patients with diarrhea. • 3-9g • Chan Tui - Cicada Slough / Periostracum Cicadae • cold, sweet, salty • LU, LR A&I: Wind-heat sore throat. Vents rashes, relieves itching. Clears eyes. Stops spasms/ convulsions. • C&C: Caution during pregnancy • 3-9g • Sang Ye - Mulberry leaf / Fm Mori • cold, sweet, bitter • • LU, LR A&I: Wind-heat dry cough. Clears liver heat & brightens eyes. 4.5-15g • Ju Hua - Chrysanthemum flower / Fl chrysanthemi • sl cold, sweet, bitter • LU, LR A&I: Wind-heat, clears head & eyes. Calms liver & brightens eyes. • C&C: Caution in Qi deficiency, diarrhea • 4.5-15 g • Man Jing Zi - Vitex Fruit / Fr Viticis • cool, acrid, bitter • A&I: Wind-heat headache or eye pain. Damp Bi • • LR, UB, ST C&C: Caution for headaches or eye problems due to def Yin or Blood. 6-12 g • • • • Dan Dou Chi - Prepared Soybean / Sm Sojae Preparatum cold, sweet, sl bitter LU, ST A&I: Mildly releases exterior. Relieves restlessness. Inhibits lactation 6-12g • Ge Gen - Pueraria root / Rx Puerariae • cool, acrid, sweet • • • • SP, ST A&I: Exterior pattern stiff neck. Vents rashes. Raises Yang & stops diarrhea. Promotes fluids & relieves thirst. Roasted yellow for diarrhea. Pueraria flower (Ge Hua) is sweet & neutral, relieves alcohol toxicity 6-12 g • Chai Hu - Bupleurum root / Rx bupleuri • cool, bitter, acrid • • • LR, GB, PC, TB A&I: Shaoyang pattern. Liver Qi stagnation. Raises Yang-Qi. C&C: Contraindicated for rising liver Yang or deficient Yin. Overdose causes nausea/vomiting 3-12 g • • • • • Sheng Ma - Cimicifuga rhizome / Rhizoma Cimicifugae cool, acrid, sweet LI, LU, SP, ST A&I: Vents rashes. Upper body fire toxins. Raises Yang-Qi. Envoy, guides herbs upwards. C&C: Contraindicated for xs above w/ def below, latestage rashes, def Yin or rising liver heat 1.5-9g