Infective causes of diarrhoea

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Infective diarrhoea

By

Remilekun Odetoyinbo

GPST1

Causes

• Bacteria campylobacter salmonella e-coli

Shigella Staph clotridium

Cholera

• Viral

Rota, Adeno, Noro virus

• Parasites like giardia,

• Worms hook worms,pin worms

• Others amoebic dysentery

Signs and symptoms

• Diarrhoea

• Abdominal pain

• Vomiting

• Fever

• Bloating

• Weight loss

• Malaise

• nausea

• E coli.

• Commonest cause of travellers diarrhoea

• Main route is feacal to oral transmission .

• Can get it from contaminated vegetables, cheese

• Can be treated with amoxicillin or cephalosporin

• Clostridium difficile.

• Most serious cause of antibiotic associated diarrhoea.

• Presentation is mainly after antibiotics with abdominal pain , bloating, loose foul smelling stools

• Can be treated with metronidazole or vancomycin if no response.

Viral causes

• Rota Virus

• Commonest cause of severe diarrhoea in infants and children.

• Incubation period of 2 days

• Symptoms start with vomiting followed by 4-8 days of watery stools

• More associated with dehydration than bacterial causes.

• Symptomatic management and rehydration is essential

Viral causes

• Noro virus affects all ages

• Common in semiclosed or closed communities. camps, hospital, dormitories

• Transmitted from person to person or from contaminated food and water

• Incubation period 1-2 days.

• Last for 24-60 hours.

• Symptoms are mainly forceful vomiting, diarrhoea, abdominal pain

• Handwashing is essential to reduce spread.

• Gardia Lamblia.

• Protozoa parasite.

• Got from contaminated water or faecal –oral transmission.

• Causes villous atropy.

• Presents with weight loss, bloating steatorrhoea epigastric pain nausea and explosive diarrhoea

• Treat with metronidazole first line . Others tinidazole ,nitazoxamide

QUIZ

• Most common cause of severe diarrhoea in infants and children

• The cause of 90% of non bacterial outbreaks of diarrhoea in the world.

• Antibiotic of choice for campylobacter

• Commonest cause of travellers diarrhoea.

• Antibiotic of choice for Clostridium difficille

A Rota virus

B E-coli

C Noro virus

D Metronidazole

E Erythromycin

True or false

1 Gardia lamblia is a protozoan

2 Dehydration is twice more likely to occur in diarrhoea of bacteria origin than with rota virus

3 Noro virus infection can follow breathing air near an episode of vomiting .

4 Alcohol gel is inadequate for infection control when in contact with noro virus patients

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