GLENN CHENEY Senior Manager Technical Communication Pharmanex R&D Weight Management 2 COMPONENTS 1 3 Healthy Eating Daily Activity in Shakes & Supplements EAT ONE HEALTHY MEAL Protein Vegetables Fat Dairy Fruits Complex Carbs • F&V – Correlation between F&V consumption and body composition • PROTEIN – for satiety and muscle tone • COMPLEX CARBS – affects rate of energy absorption • FAT – For satiety • DAIRY – correlation between dairy consumption and body composition (also protect against calcium loss) REPLACE TWO MEALS WITH AC SHAKES REPLACE TWO MEALS WITH AC SHAKES EFFECT OF A SPECIAL FIBER IN AC SHAKES Without unique fiber EFFECT OF A SPECIAL FIBER IN AC SHAKES Without unique fiber Effect of special fiber in AC Shakes • Unique fiber blend promotes fullness • Balance blood sugar • ↓ cravings, so you consume fewer calories REPLACETHREE TWO MEALS SNACKSWITH A DAYAC SHAKES 10-14 nuts ½ apple + 2 tsp PB 1 Healthy Eating 2 3 1 Healthy Eating Daily 2 3 • 5 ─7× Per Week • Ultimate Goal: 1 Hour per day Activity – Break it up into 10 min increments – 10 min × 6 per day = 60 mins – Gradually build up to 60 mins • Don’t pick activities you dislike – Play Wii Sports / “Just Dance” with your kids • Be accountable to yourself & others 1 Healthy Eating 2 Daily Activity 3 in Shakes & Supplements PROVEN INGREDIENTS; THE RIGHT DOSE • Garcinia cambogia fruit extract • Gymnema sylvestre extract • Chromium • Forskohlii extract • Lagerstroemia speciosa • Fenugreek fiber EQUIVALENT TO 20 CAPSULES! • • • • • • 4,700 mg 400 mg 400 mcg 425 mg 48 mg 2,000 mg AC COMPLEX AND AC SHAKES TOGETHER: + = 100% Clinically Effective Dose GREEN TEA STUDIES Green Tea improves Body Composition 90 days; subjects received Green Tea catechins ↓ intra-abdominal fat (IAF) by 5.6 cm2 ↓ in waist circumference Wang H, et al. Effects of catechin enriched GT on body composition. Obesity. 2010 Apr;18(4):773-9. 90 Day RCT of Green Tea 60 subjects: BMI > 25 Week 8: No difference in food intake, or physical activity Δ in resting energy expenditure = 183.38 kJ/day (p < 0.001) Week 12: Stress response* significantly ↓ (p < 0.05) *VMA Auvichayapat et al. Effectiveness of green tea on weight reduction in obese Thais: A randomized, controlled trial. Physiol Behav. 2008 Feb 27;93(3):486-91. EFFECTS OF STRESS ON APPETITE High Cortisol Individuals: – Consumed more calories – Ate significantly more sweet foods – More negative moods Dietary Restraint = consciously trying to limit food intake to maintain a desired body weight HIGH DIETARY RESTRAINT IS ASSOCIATED WITH HIGH CORTISOL 1. Epel ES, et al. Psychoneuroendocrinology 2001;26:37-49. 2. McLean JA, Barr SI, Prior JC. Am J Clin Nutr 2001;73:7-12. + 63% 40 Treadmill (min) Time to Exhaustion AGELOC VITALITY IMPROVES PHYSICAL ENDURANCE 30 20 10 Week 5 Week 0 Week 5 Control Week 0 ageLOC Vitality AGELOC VITALITY PRESERVED 57% MUSCLE GLYCOGEN COMPARED TO NON-TREATMENT GROUP Muscle glycogen (mg/g wet wt.) 2.0 0.25mg/g (-13%) 1.8 0.575mg/g (-30%) 1.6 1.4 1.2 1.0 Non-Exercise Control Exercise Exercise w/ ageLOC Vitality Results from a pre-clinical study in mice with ageLOC Vitality Blend. Ferguson et al. Targeting Mitochondria 2010 Berlin, Germany November 18-19, 2010. 1.05 Carbohydrate Burning Zone 1.00 (RER) Respiratory Exchange Ratio AGELOC VITALITY INGREDIENT PROMOTES FAT METABOLISM DURING PROLONGED EXERCISE Includes: glucose and glycogen 0.95 0.90 0.85 0.80 Fat burning Zone 0 20 40 60 Exercise Time (minutes) Pharmanex ingredient study by Fit Stop Human Performance Laboratory Medicine and Science in Sports and Exercise 2001; 33(5) Supplement 1:pg S164 Before an ageLOC Vitality ingredient After 6 weeks of an ageLOC Vitality ingredient 1 Healthy Eating 2 Daily Activity 3 in Shakes & Supplements 1 + + = 2 3 = WEIGHT MANAGEMENT SUCCESS