LIVE IN THE MOMENT! “The secret of health for both mind and body is not to mourn for the past, not to worry about the future, or not to anticipate troubles, but to live in the present moment wisely and earnestly.” -Buddha Ophthalmic Diseases Chapter 4 Common Diseases of Companion Animals Ophthalmic Diseases Conjunctivitis • CONJUNCTIVA: pink tissue that lines the inner surface of the eyelids and covers the front portion of the eyeball except for the cornea • Causes – Allergy (atopy) – Anatomic (ectropion, entropion) – Bacterial infection (predisposed by): • • • • Injury ↓Tear production Foreign body Respiratory disease (bacteria, virus) • Causes (in cats it is usually infectious) – – – – Feline herpes virus (most common cause of bilateral conjunctivitis) Calicivirus Chlamydia psittaci bacteria Mycoplasma Red, congested/swollen, painful Conjunctivitis • Signs – Redness – Chemosis (swelling of conjunctiva) – Ocular discharge (tears, mucus) • Diagnosis – Determine 1º disease, if any – Rule out FB – Rule out ‘dry eye’ in recurrent cases • Schirmer tear test – 1 min- tears show as blue dye SCHIRMER TEAR TEST Cats: 11-23mm Conjunctivitis • Rx – Topical antibiotic ointment • neomycin/bacitracin/polymyxin B(BNP or triple antibiotic) • Gentamicin ophthalmic ointment • Antibiotic w/ cortisone (if cornea is intact) • Client info – Do not allow dogs to ride with head out window – Keep medial canthus of eye clean (warm water, clip hair) – Vaccinate kittens to prevent URI – Do not touch eye with applicator – Discard unused medication Epiphora • EPIPHORA: excessive tearing • Causes (2 causes) – Overproduction of tears • Ocular pain, irritation (from hair, etc) – Faulty drainage by lacrimal system • Blockage of duct (swelling, inflam) • Blockage of puncta (hair, debris) • Imperforate puncta (no opening) – Cockers – Poodles • Trauma Epiphora Signs Watering of eye Discoloration of hair Dx Fluorescein dye test Dye at nose shows duct is open Rx Treat 1º cause Flush lacrimal ducts Surgically open imperforate puncta Topical antibiotic ointment Keep hair trimmed around eyes May act as a wick Client info Staining due to pigment in tears, not blood Some dogs have life-long problem EPIPHORA FLUSHING THE NASOLACRIMAL DUCT Entropion: eyelids that roll in against the cornea • Causes – Congenital • large orbits w/ deep-set eyes (poor lid support) – Collies, G. Dane, I. Set, Dobe, G. Ret, Rott, Weim • Poor ocular muscle development – Chesapeake, Labs, Chow, Samoyed – Trauma → scarring with distortion of lid – 2º to painful corneal lesion, conjunctiva inflammation (most common cause in cats) • Signs – Epiphora (tearing) – Chemosis (swelling of conjunctiva) – Conjunctivitis – Pain – Corneal ulceration (±) – Photophobia Entropion • Treatment – Surgical correction is treatment of choice • Temporary mattress suture to evert eye (young animal) • Lateral canthoplasty (to shorten eye lid) • Hotz-Celsus: Remove elliptical piece of tissue from under eye Ectropion • Causes – Congenital • Bassets, Blood, C Span, E Bull, St Bern • Signs – Conjunctivitis – Epiphora – Keratitis (corneal inflammation/scarring), usually from exposure – Purulent exudate • Rx – Surgery to shorten eye lid – Other procedures Hypertrophy and Prolapse of 3rd eyelid gland Hypertrophy and Prolapse of Nictitans Gland (Cherry Eye) Nictitating membrane is the 3rd eyelid; is a protective structure Produces ~30% of tears • Cause is unknown – Bassets, Beagle, Bos. Terr, C. Span • Signs – Young dog (<2 y) – Epiphora – Usually no pain • Dx – r/o tumor in older dogs and cats • Rx – Sx to remove gland is an option , but not recommended – Suture back in place Glaucoma Aqueous humor provides nourishment to lens and cornea Increased intraocular pressure; → Blindness Normally, the amt of fluid produced = amt of fluid leaving eye Normal: Dog/Cat—12-22 mm Hg • Causes – Inherited (C Span, Basset, Chow) – Secondary—obstruction of drainage angle • • • • • Neoplasia Luxation of lens Hemorrhage Uveitis (ciliary body, iris, choroid) Signs – – – – – Ocular pain Episcleral injection Corneal edema Dilated pupil (unresponsive to light) Blind (±) IRIDOCORNEAL ANGLE Glaucoma • Dx – IOP>30 mm Hg • Rx – Acute (this is an emergency; prevent blindness) • Latanoprost (Xalatan 0.005%) – Facilitates aqueous outflow • Dichlorphenamide (Daranide) – Decreases aqueous production • Surgical – Cryosurgery or laser (destroys part of ciliary body) » Decreases aqueous production – Chronic • Enucleation to relieve pain Schiotz Tonometer Tono-Pen Ulcerative Keratitis (Corneal Ulcers) Ulcers usually heal within a few days • Causes – – – – – – Trauma Chemical burns Foreign objects KCS (Keratoconjunctivitis Sicca) Conformational abnormalities Herpes virus (cats) • Signs – – – – Pain Epiphora Blepharospasm (eyelid spasm) Hyperemia of conjunctiva • Dx—Fluorescein dye to cornea Herpes virus Ulcerative Keratitis (Corneal Ulcers) • Rx – Topical atropine (1%) ointment (Debate over benefits and how long to use) • Decrease pain, blepharospasm – Topical broad-spectrum antibiotic ointment – Viral ointments or solutions (Viroptic for cats with herpes virus) – Surgery • Eyelid flap, conjunctival flap – Serum (autologous) • Blocks proteases released from leukocytes and bacteria (helps prevent continued collagen loss) – keep in refrigerator (throw out after 72 hours) Deep Corneal Ulcer • Desmetocele – erosion to membrane Ulcerative Keratitis (Corneal Ulcers) • Client info – Most ulcers heal quickly with treatment – Avoid using old medications – Rx with cortisone will inhibit healing of ulcer – Do not touch eye with ointment applicator