Common Dermatology Terms Tanner Bartholow Macule erythema infectiosum http://www.pediatrics.wisc.edu/education/derm/tuta/macule.html “A macule is a change in the color of the skin. It is flat, if you were to close your eyes and run your fingers over the surface of a purely macular lesion, you could not detect it. A macule greater than 1 cm. may be referred to as a patch”1 Papule • “A papule is a solid raised lesion that has distinct borders and is less than 1 cm in diameter. Papules may have a variety of shapes in profile (domed, flat-topped, umbilicated) and may be associated with secondary features such as crusts or scales” 1 scabies molluscum contagiosum http://www.pediatrics.wisc.edu/education/derm/tuta/papule.html Nodule http://www.pediatrics.wisc.edu/education/derm/tuta/nodule.html http://www.pathguy.com/lectures/erf05_basal_cell_ca_arising.jpg Basal cell carcinoma “Nodule is a raised solid lesion more than 1 cm. and may be in the epidermis, dermis, or subcutaneous tissue” 1 Plaque http://www.pediatrics.wisc.edu/education/derm/tuta/plaque.html tuberous sclerosis psoriasis “A plaque is a solid, raised, flat-topped lesion greater than 1 cm. in diameter. It is analogous to the geological formation, the plateau”1 Vesicle http://z.about.com/d/dermatology/1/0/M/5/three_lesions.jpg http://dermatology.about.com/od/dermphotos/ig/Chicken-Pox-Pictures/chickenpox22.htm “Vesicles are raised lesions less than 5mm. in diameter that are filled with clear fluid (blister)”1 Bulla Bullous pemphigoid http://www.aafp.org/afp/20020501/1861_f4.jpg “Vesicles are raised lesions greater than 5mm. in diameter that are filled with clear fluid (blister)”2 Pustule http://www.pediatrics.wisc.edu/education/derm/tuta/pustule.html Group A Strep infection “Pustules are circumscribed elevated lesions that contain pus. They are most commonly infected (as in folliculitis) but may be sterile (as in pustular psoriasis)”1 Wheal (hive) http://www.pediatrics.wisc.edu/education/derm/tuta/wheal.html “A wheal is an area of edema in the upper epidermis”1 “Edematous, transient papule or plaque caused by infiltration of dermis by fluid”2 Scales Seborrheic dermatitis “Excessive number of dead keratinocytes produced by abnormal keratinization”2 Petechiae, Purpura, Ecchymoses “The term "petechiae" refers to smaller lesions. "Purpura" and "ecchymoses" are terms that refer to larger lesions. In certain situations purpura may be palpable. In all situations, petechiae, ecchymoses, and purpura do not blanch when pressed.”1 Henoch-Schönlein Purpura Thrombocytopenia Quiz http://www.kidsgrowth.com/images/fp_images/mongolian_spot.jpg http://www.mdconsult.com/das/pdxmd/media/1127/6112715/large.jpg http://www.mycology.adelaide.edu.au/gallery/photos/malass1.gif • 1. Macule/patch (mongolian spot) • 2. Plaque (psoriasis) • 3. Macule/patch (tinea versicolor) Treatment of purpura fulminans – Study from 7 burn centers over a 10 year period (70 total patients)3 • Neisseria meningitidis most common in infants through adolescents • Streptococcus most often found in adults • Treatments consisted of antibiotic treatment of the underlying infection • Volume replenishment and ventilatory and inotropic support • Corticosteroids used (38%) of time • Protein C replaced in (9%) of patients • Skin grafting and amputations required in (90%) • 25% amputation of all extremities • Early fasciotomoies reduced amputation in 6 of 14 patients Resources 1. Williams, D., and M. Katcher. Nomenclature of Skin Lesions: Primary Care Dermatology Module. Wisconsin Area Health Education Center (AHEC) System. 2003. <http://www.pediatrics.wisc.edu/education/derm/index.ht ml> 2. Goljan, E. 2007. Rapid Review Pathology. 2nd Ed. Mosby Elsevier. Philadelphia. 3. Warner PM, Kagan RJ, Yakuboff KP, et al. Current management of purpura fulminans: a multicenter study. J Burn Care Rehabil 2003; 24: 119-126.