Definition Acute bacterial infection of the mucosa of one or more paranasal sinuses, usually rhinogenic in origin and is characterized by acute facial pain/ head ache and purulent nasal discharge. Anatomical considerations: Osteo-meatal complex Types • Depending on the site – – – – Unilateral/ bilateral Pansinusitis Multisinusitis Maxillary/ frontal/ ethmoidal/ sphenoidal • Depending on whether the sinus is draining or not – Open type – Closed type • Depending on the pathology – Suppurative – Non-suppurative Etiology • Rhinogenic- Commonest (85%) – Usually after viral rhinitis (Flu) – Any form of rhinitis • Dental (Maxillary) – Root abscess, dental procedure, etc. • Trauma – RTA, Swimming and diving, FB, barotrauma, etc. – Iatrogenic- nasal packing, septal surgery • Hematogenous- Rare Predisposing factors for Acute rhinosinusitis • Mucosal odema of MM – Any form of rhinitis: Viral, bacterial, Irritant, allergic, VMR, atrophic, etc. (environmental factors play role) • Mechanical (anatomical) obstruction of nose/ MM – DNS, spur, polyp, hypertrophic turbinate, any mass, FB, nasal packing, etc. • Pathological mucous – Thick mucous (mucoviscidosis, cystic fibrosis) • Primary mucociliary dysfunction • Others: Poor general health, immunodeficiency states, DM, nutritional deficiency, etc. Bacteriology • • • • • • Str.Pneumoniae B-hemolytic streptococcus H.influenzae Stap. Aureus Klebsiella pneumoniae Others Pathogenesis • Obstruction to sinus ostium/ meatus • Stasis of secretions (serous-mucinous): Nonsuppurative • Secondary bacterial invasion: Suppurative • Severity and resolution depends on – – – – Open/ closed. May drain creating accessory opening. Organism virulence Host resistance Treatment received Pathology • Acute inflammatory changes: Hyperemia, odema, acute infl. infliterate. • Increased activity of the mucous glands • Severe suppuration Mucosal destruction Empyema Bony destruction Complications Difference between healthy and inflammed Sinus Clinical features: Symptoms Depends on the sinus involved • Constitutional symptoms: Fever, malaise, lethargy • Headache/ facial pain: Dull ache, postural/diurnal. – – – – Max: Facial, forehead Frontal: Forehead, “Office headache” Ethmoid: Between the eyes, may > with eye movement Sphenoid: Vertex, occipetal • Nasal discharge – mucous/ mucopurulent/ purulent/ blood stained – Anterior/ postnasal • Nasal obstruction • Cheek/ lid congestion, swelling Clinical features: Signs Depends on the sinus involved • • • • • • • • • Fever Tenderness Cheek swelling Lid odema: in ethmoid and frontal Inflamed nasal mucosa especially the meatus Discharge in MM/ SM as on anterior/posterior rhinoscopy Postural test Transillumination test Signs of complications Endoscopic appearance of acute infective sinusitis, with pus exuding from under the right middle turbinate and down into the middle meatus. Investigations • Clinical diagnosis • Diagnostic nasal endoscopy (DNE) • Radiological – X-ray PNS • • • • Water’s view (Occipetomental) Caldwel view (Occipetofrontal) Lateral view Base skull view (Submento-vertical) – CT scan: indicated in impending complications • C/S: rarely done Normal Sinuses Acute Maxillary Sinusitis Treatment- Medical • • • • • • Antibiotics Nasal decongestants (Topical/systemic) Anti-inflammatory analgesics Medicated steam inhalation Mucolytics Hot fomentation Surgical drainage • If not responding to medical treatment • Impending or manifest complications • Depends on the sinus involved Drainage procedures • Acute maxillary: Antral washout/ endoscopic MMA • Acute frontal: Frontal trefination/ endoscopic frontal recess clearance • Acute ethmoiditis: External ethmoidectomy/ endoscopic ethmoidectomy • Acute sphenoiditis: External sphenoethmoidectomy/ endoscopic sphenoidotomy Complications • Chronic sinusitis • Acute sinusitis or acute exacerbations of chronic sinusitis may give rise to following complications: Orbital Intracranial Osteomyelitis Septic focus for other infections Signs of impending/ manifest complications Spiking fever Lid odema, facial/orbital swelling Proptosis, reduced vision, reduced extraoccular movt. Severe headache and hyperirritable Projectile vomiting Meningeal signs Hypothermia Altered sensorium Orbital complications • Common in acute ethmoiditis or frontal sinusitis • Direct spread/ ostitis/ thrombophlebitic • Odema of the lids • Subperiosteal abscess • Orbitial cellulitis • Orbital abscess • Superior orbital fissure syndrome: Deep orbital pain, frontal headache, progressive paralysis of extraoccular movements • Blindness A patient with acute ethmoiditis threatening vision Intracranial • Anterior cranial fossa and cavernous sinus closely related • Meningitis • Extradural abscess • Subdural abscess • Frontal lobe abscess • Cavernous sinus thrombophlebitis, etc LATERAL SINUS THROMBOSIS DELTA SIGN BRAIN ABSCESS Conclusion “Acute sinusitis especially in a child should be treated adequately to prevent consequent chronic sinusitis or other more severe complications which may be even fatal”.