Management of Acute Myocardial Infarction Sivanandam Vasudevan Management of Acute Myocardial Infarction • Pre Hospital Phase • ER • CCU • Step-down - Telemetry • Post Hospital Phase Complications of Acute Myocardial Infarction • Arrhythmic Complications • Mechanical Complications • Ischemic Complications • Miscellaneous Complications [DVT, PE, Pericarditits, TPA complications, Pneumonia] Arrhythmic Complications [Early < 24 hrs & late >24 hrs] • Ventricular – PVC, V tach/V Fib • Atrial – PAC, SVT, A Fib • Bradycardia – Sinus • AV block – Complete Heart Block • LAFB, LPHB, LBBB & RBBB Mechanical Complications of Acute Myocardial Infarction • Papillary Muscle Rupture – Acute MR • Ventricular Septal Defect • Right Ventricular MI • Free Wall Rupture • Cardiogenic shock • Cardiac Tamponade Hemodynamic findings in complications causing cardiogenic shock with acute MI (a) • Ac Pul edema • Shock • MR Mechanisms causing MR during an acute MI and their treatment modalities Rupture of papillary muscle, a rare complication of acute MI (a) Rupture of papillary muscle, a rare complication of acute MI (b) Transesophageal echocardiogram in the four-chamber view Hemodynamic findings in complications causing cardiogenic shock with acute MI (b) • Ac Pul edema • Shock • Systolic murmur Ventricular Rupture [VSR] Ventricular septal rupture (a) Ventricular septal rupture (b) Hemodynamic findings in complications causing cardiogenic shock with acute MI (c) • CHF • Clear lungs • Hypotension • Systolic murmur • Inf. MI ECG V4 R Hemodynamic findings in complications causing cardiogenic shock with acute MI (d) Hemodynamic findings in complications causing cardiogenic shock with acute MI (e) • BP < 90 • Tachycardia • Pul edema • Confused • Skin cold clammy • Ant. MI • Mortality 80% Regional acute MI, infarct expansion, chamber thrombosis and aneurysm formation (a) Regional acute MI, infarct expansion, chamber thrombosis and aneurysm formation (b) Regional acute MI, infarct expansion, chamber thrombosis and aneurysm formation (c) Regional acute MI, infarct expansion, chamber thrombosis and aneurysm formation (d) CT of patients with stroke as a complication of MI (a) B © 2003 Science Press Internet Services CT of patients with stroke as a complication of MI (d) CT of patients with stroke as a complication of MI (c) © 2003 Science Press Internet Services CT of patients with stroke as a complication of MI (e) © 2003 Science Press Internet Services © 2003 Science Press Internet Services Incidence of cardiogenic shock complicating acute MI Incidence of cardiogenic shock complicating acute MI INCIDENCE OF MECHANICAL, CAUSES &percnt; OVERALL INCIDENCE OF CARDIOGENIC SHOCK (INCIDENCE ON PRESENTATION), &percnt; STUDY LV FREE WALL RUPTURE ACUTE VSR ACUTE MR Prethrombolytic era Killip and Kimball &lsqb;6&rsqb; 19 - - - Scheidt &lsqb;4&rsqb; 15 - - - Hands et al. * &lsqb;3&rsqb; 7.1 - - - Goldberg et al. † &lsqb;5&rsqb; 7.5 (3.2 ) - 0.9 3.9&percnt; GISSI-1 &lsqb;20&rsqb; -(2.4) - - - LATE ¶ &lsqb;21&rsqb; - 3.4 - - TIMI-II &lsqb;18&rsqb; 5.8 (1.5) - - - ISIS-3 &lsqb;17&rsqb; 7.0 1.3 - - GUSTO &lsqb;19&rsqb; 6.1 (0.8) - 0.5 1.7 ‡ § Thrombolytic era * Excludes patients with shock on presentation. † ‡ § ¶ 14&percnt; received thrombolytics. 1976-1988: incidence unchanged. Within 24 hours of presentation. Includes all known and suspected cases of rupture. Rupture of the heart complicates acute MI in about 10% of cases Ischemic Complications Post Myocardial Infarction Chest pain Post MI • Recurrent angina • Recurrent MI • Pericarditis[ Acute & Dressler’s ] • Pneumonia • Pulmonary Embolism • Shoulder hand syndrome CT of patients with stroke as a complication of MI (a) Management of Acute Myocardial Infarction Pre discharge work up • Secondary prevention – Diet, Exercise, Weight control, Smoking cessation • Lipid control • B Blockers, ACE Inhibitors, ASA, Statins • Cardiac Rehabilitation • Discharge planning • Pre discharge ECHO, Stress test Management of Acute Myocardial Infarction Thank You