PolyBone NuroSpine Cranio-Facial Bone defect * Trauma * Surgically induced * Cranio-facial bone tumor Awesome to patients & surgeons due to cosmetic problems Esp) pterional approach (bone defect & delayed temporal m. atrophy) PMMA(acryl cement, Resin) * Most commonly used in Cranio-Facial defect area. * Advantages 1. Low Price 2. High Mechanical Strength * Disadvantages 1. May Marked Inflammation Response 2. Fibrous Encapsulation of Implant -> Possibility of Infection & loosening of implant PMMA(acryl cement, Resin) * Disadvantages 3. High temperature (1100 C) generated -> Tissue damage 4. Shaping of Contour of implant after hardening is difficult 5. Never convert to Bone 6. No Bone bonding effect -> Need fixation device (wire, craniofix etc.) Calcium Phosphate Cement Advantages: - Biocompatible material Have bone conduction activity Easily handling Good osteointegration Converted to Bone Disadvantages: - Low tensile strength than PMMA - Higher cost PolyBone * Brushite Calcium phosphate Cement(CPC) -> Convert to bone is fast than other CPC * Included Poly-phosphates (Poly-P) : patent -> Poly-P have bone induction activity -> So, PolyBone have both bone induction & conduction activity PolyBone * BoneSource hardening time: 10-20 mins PolyBone hardening time : within 5 mins * Good Bone bonding effect -> No need of fixation device such as wire or craniofix etc . PolyBone * Easily making contour during application & after hardening - such as knife, or sharp instrument * Augumentation during the procedure is possible (esp. temporal area) Tips If dura was slack down below the inner cortex of bone margin at the bone defect area, put the gelform on the dura at the bone defect area. -> not to compress the brain by PolyBone Tips If you anticipated of delayed temporal muscle atrophy, Augmentation of temporal bone area with CPC is possible. Tips It is recommended to use each 5 g package separated. Well adhesion of new CPC to already hardening CPC. Application of PolyBone on Craniofacial part Reconstruction of cranial defects -> If larger defect than 10cm2, use of wire mesh is recommended. Closure of frontal sinus opening Fronto-temporal contouring (Aneurysm Op.) Clinical Application on craniofacial area of PolyBone Clinical Application Fronto-orbito-zygomatic approach Onlay grafting for augmentation & smoothing contours of skeletal irregularities MVD Op. Clinical Application Augumentaion of nasoglabellar, supraorbital rim, mandible Lateral skull base reconstruction Translabyrinthine approaches & other skull base approach Clinical Application All of these are non-stress-bearing areas in craniofacial skeleton Contraindications of PolyBone Infected field Areas surrounding nonviable bone Abnormal calcium metabolism Metabolic bone diseases Recent untreated infection Poor wound healing Immunologic abnormalities Bone Setting CT X-Ray & 3-D CT Closure of Oro-Antral Fistula Closure of Frontal Sinus Opening Closure of Frontal Sinus Opening Augmentation of temporal area to compensate delayed temporal M. atrophy MVD Op Obliteration of Sella Floor after Trans-Sphenoidal Approach Clinical Application of PolyBone (Aneurysm Cases) KIM, K Y (F/55) Rt. MCA Aneurysm KIM, J Y (M/69) Pericallosal Aneurysm KIM, T J (F/63) A-com Aneurysm PARK, K H (F/59) P-com Aneurysm MCA Aneurysm PARK, K H PARK S D (M/53) A-com Aneurysm MCA Aneurysm PARK Y J (F/65) MCA Aneurysm PARK Y J SIN Y S (F/49) ICA bifurcation Aneurysm SIN J H (F/74) P-com Aneurysm SIN J H JANG M J (F/58) MCA Aneurysm JANG S S (F/67) MCA Aneurysm A-com Aneurysm JANG S S JANG J Y (F/70) P-com Aneurysm JEON M J (F/54) MCA Aneurysm JEON M J JEON Y J (F/66) Lt. MCA Aneurysm Rt. P-com Aneurysm Lt. MCA An. OP JEON Y J Post- 2nd Op. Not repaired on Rt. side HAN S H (F/68) Pericallosal Aneurysm Well developed Frontal sinus Obliteration of opening of the frontal sinus HWANG Y H (M/43) MCA Aneurysm Impact Block type Polybone in Pterion burr hole site HWANG Y H YOON M Y (F/60) A-com Aneurysm