Acute Upper GI Bleed:

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Acute Upper GI Bleed:

Case 1

 64/C/M presented to the A&E with c/o

SOBOE, giddiness and lethargy.

 He gives a history of passing out black tarry stools yesterday.

 He has been taking diclofenac sodium regularly due to bilateral knee pains.

 He has also drinking alcohol regularly, i.e. 2 large bottle of beers daily.

 How important are the colour of his stools?

 What are the possible causes of his GI bleed?

 What other physical signs are helpful to determine the cause of GI bleed?

Physical examination

 The patient was found to be drowsy, with

M5V3E3 (GCS 11/15)

 BP was 95/70 mm Hg

 HR 110 bpm

 Peripheries was cold and clammy

 Pulse was feeble

 SpO2 95%

 What is the causes of the low GCS?

 What is the significance of the vital signs recorded?

 You find that he has 8 spider naevis, absence of axillary hair and gross ascites.

 He has a flapping tremor.

 He also has multiple bruising over the extensor surfaces of his arms.

 What could be the other cause of his low

GCS?

 State the stages of hepatic encephalopathy.

Suddenly, he develops haemataemesis.

Do you insert a Ryle’s tube? State your reasons for doing so.

 You check the vital signs again :

– BP 84/50 mm Hg

HR 150 bpm

GCS M3V2E1 (6/15)

– SpO2 89%

 Why has the vital signs worsened?

 Why has he become more hypoxic?

 What do you do now?

 List down your approach to stabilizing this patient.

Investigation results

 TWC 13.5

 Hb 6.0

 MCV 80

 MCH 30

 Plt 500

 Explain the results above.

 Would you expect hypochromic microcytic anemia?

 APTT 40

 PT 15

 INR 1.8

 What are the possible causes?

 What other tests to order to elucidate the cause?

 Urea 28

 Creat 140

 Na 130

 K 3.7

 Explain the results above.

 TP 60, alb 23

 ALT 878

 ALP 30

 Explain the results.

 RBS 3.0

 Why?

 What blood products do you want to give and why?

 What is the target Hb in this patient?

 List all the problems / diagnosis of this patient.

 What is the definitive treatment of this patient?

 Are there any drugs which helps reduce bleeding?

 Are antibiotics needed in this patient?

 What is the follow up care for this patient?

Case 2

 60 year old man presents with 1 week history of malaena and shortness of breath?

 On examination he his pale and cachexic.

 Hb 9.0g/dL MCV 60 MCH28

 PR showed malaena, examination of the abdomen was unremarkable.

 BP 120/80 mm Hg

 HR 99 bpm

 What could be the possible causes of his

UGIB?

 What investigations would you send?

 Would you transfuse him with blood?

 What are the indications for blood transfusion?

 How fast would you transfuse the blood?

 Do you need to give IV Frusemide as well?

 OGDS showed a Forrest IIc ulcer.

 What does this mean?

 How can the ulcer be treated endoscopically?

 What drugs should the patient be given?

 Patient asks you what are the risks for

OGDS. What do you say?

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