Intro mHealth The practice of medicine and public health supported by mobile devices has emerged in recent years for developing countries as a means of providing greater access to larger segments of a population and improving the capacity of health systems in such countries. • Tool for HIV Adherence Promotion • 2 recent RCT supporting mhealth & ART adherence: • Lester RT et al. Effects of a mobile phone short message service on antiretroviral treatment adherence in Kenya (WelTel Kenya1): a randomised trial. Lancet 2010 • Pop-Eleches C et al. Mobile phone technologies improve adherence to antiretroviral treatment in a resource-limited setting: a randomized controlled trial of text message reminders. AIDS 2011; WELTEL KENYA: USING MOBILE PHONES AS A COST-EFFECTIVE HEALTH INTERVENTION HIV/AIDS SUPPORT Richard.Lester@bccdc.ca bella@weltel.org Intro Weltel Kenya1 (Lancet 2010) Effects of a mobile phone short message service on antiretroviral treatment adherence in Kenya • 538 patient randomised control trial (RCT) initiating ART • 2 arms: 1. SMS intervention 2. Control/Standard of Care • SMS intervention arm: • 1 weekly SMS for 1 year • Respond within 48 hours • Patients responding problem & non-responders called back • Results: • SMS intervention group: significant improvements in adherence and viral suppression • Viral Load Suppression: 57% intervention vs 48% control • ART adherence (>95%): 62% intervention vs 50% • Viral load suppression NNT = 11 • ART adherence NNT= 9 WELTEL KENYA: USING MOBILE PHONES AS A COST-EFFECTIVE HEALTH INTERVENTION HIV/AIDS SUPPORT Richard.Lester@bccdc.ca bella@weltel.org Methods & Results Scale-up Costs 2. 1. Kenya – approx. 500, 000 ART patients PEPFAR (global) – approx. 2.5 million ART patients WELTEL KENYA: USING MOBILE PHONES AS A COST-EFFECTIVE HEALTH INTERVENTION HIV/AIDS SUPPORT Activity Based Costing – SMS Intervention: •$11.75 USD/year per patient – Kenya •$10.21 USD/year per patient - PEPFAR Cost Savings Richard.Lester@bccdc.ca bella@weltel.org Methods & Results Kenya (n= 500,000) WELTEL KENYA: USING MOBILE PHONES AS A COST-EFFECTIVE HEALTH INTERVENTION HIV/AIDS SUPPORT Richard.Lester@bccdc.ca bella@weltel.org Methods & Results PEPFAR (n=2.5 million) WELTEL KENYA: USING MOBILE PHONES AS A COST-EFFECTIVE HEALTH INTERVENTION HIV/AIDS SUPPORT Richard.Lester@bccdc.ca bella@weltel.org Future Directions/Challenges • Scale up and Implementation • Funding: 1. Patient 2. Health Systems/Programs (** major funder) 3. Industry • Pharma • Mobile WELTEL KENYA: USING MOBILE PHONES AS A COST-EFFECTIVE HEALTH INTERVENTION • Future Research • Implementation Science– Step Wedge Study Thank You . www.weltel.org HIV/AIDS SUPPORT Richard.Lester@bccdc.ca bella@weltel.org Richard.Lester@bccdc.ca bella@weltel.org