Treatment of malignant obstruction Adjunct to surgery Treatment of CBD calculi Treatment of benign strictures Diagnostic? Failed ERCP WHO performance status Imaging Clinician/MDT discussion Coagulation status Ascites 0 – 2. In bed less than 50% of time BSIR Audit report 2009, 19.8% in hospital mortality 15.6% in hospital mortality for benign disease Audit of my procedures, 18% 30 day mortality Patients with lower WHO performance status do better Ultrasound. Confirm biliary obstruction, mass, metastatic disease, calculi CT. Confirm level of obstruction, mass, metastatic disease MRI/MRCP. Complex biliary strictures, CBD calculi, liver metastases ERCP. May have failed Malignant or benign disease Gastroenterologists Surgeons Radiologists Other Healthcare Workers Surgical. ERCP and plastic stent or PTC and Internal/External biliary drainage Palliative. ERCP or PTC and metallic Stent ERCP treatment of choice PTC and internal/external drain or plastic stent. May enable successful ERCP later INR < 1.4. Consider vitamin K, FFP and also Beriplex/Octaplex. Contain prothrombin complex concentrate. Factors II, VII, IX and X as well as Proteins C and S Platelets > 100,000. If less, consider platelet transfusion WHO performance status Check coagulation Explain procedure at least 1 day before Risks. Bleeding, bile leak, infection, pneumothorax and failure Anaesthetist GA Discuss need for airway protection Use LA When applying for consultant post ask what access you may have to anaesthetics At start of procedure Gentamicin 240 mg IV Metronidazole 500 mg IV Discuss with Microbiology Use what works best for you Chiba needle 22 gauge Trochar needle 18 gauge NEF set Stiff Terumo wire Amplatz wire Catheters. BMC and straight Self expanding stent Internal/External drains 8.5/10.5F. Discuss with your surgeon Ascites present? Drain first Ultrasound? Right lobe. Mid axillary line. Aim for xyphisternum. Left lobe. Locate with U/S and usually aim for segment III. Very gently inject 1/3 strength contrast (100) as needle is withdrawn Duct entered when contrast flows away from needle and persists Duct not entered. Change angle and try not to exit liver capsule Duct normally anterior to portal vein Pre-surgery for cholangiocarcinoma. Discuss lobe to drain. Usually the lobe being preserved. Pre-surgery for pancreatic cancer. Right lobe puncture. Palliative. Drain right, left or both? 1. Chiba needle to opacify ducts then choose duct for trochar puncture and wire etc. 2. NEF set. Single puncture then wire, dilator and access sheath Consider bile for cytology if no diagnosis Stiff Terumo to cross lesion. Use pin vice for torque Straight catheter Amplatz wire Dilator Stent/Drain 1 or 2 stage procedure? Temporary drain following stent? Plug track? Coils, gelfoam etc. Technical success >95% (BSIR audit) Unable to cross stricture, establish external drainage (8.5F internal/external drain). Further attempt after decompression usually successful. Care with drainage bag essential. Internal external drainage, try not to use bag and bung catheter. In hospital mortality 19.8%. Death or major complication 21.2% overall, 18.3% benign, 21.7% malignant. Major complications in 7.9%, haemorrhage 3.5%, renal failure 1.8% and sepsis 1.6%. Minor complications in 26.0%, pain 14.3%, sepsis 7.7% and haemorrhage 4.5%. Association with ascites, elevated INR and low platelets. 1 year survival <20% for malignant disease. Drainage more effective if stents placed across ampulla 1. Further audit of this cohort is required to determine cause of death and to demonstrate whether or not there are significant associated risk factors. 2. Given the high mortality in this group of patients further data collection will be required. Significant improvements in data completeness are required. Data submission remains voluntary, but NHS services should consider how they can make resources available to support data collection for individual operators 86 yr female presented with sepsis and subsequent jaundice Arteriopath but otherwise reasonably fit CT Abscess right lobe liver drained Antibiotics MDT discussion, for palliation ERCP, failed to stent due to large duodenal diverticulum PTC 69 yr male with obstructive jaundice CT, operable mass in head of pancreas MDT discussion Surgical candidate ERCP to place plastic stent failed PTC 75 yr female with obstructive jaundice CT, large central liver mass, likely cholangiocarcinoma. Further deposit in segment II MDT discussion, not operable, palliative PTC and stent left lobe 71 yr male Metastatic colorectal cancer Multiple liver resections Jaundice with recurrent liver and peritoneal tumour Considering further chemotherapy CT Small residual liver with mild duct dilatation ERCP failed 59 yr female with inoperable cholangiocarcinoma Previous ERCPs with plastic and finally recently metal stent into left lobe Recurrent jaundice ?percutaneous options Careful patient selection after MDT discussion “Appropriate” Anaesthesia Try not to use external drainage bags