INTRAVENOUS OZONE
THERAPY
The Direct IV Method and Anti-Aging
Dr. Howard F. Robins, D.P.M.,D.A.B.P.E.,
Member, A.A.O., Member, I.A.O.H.D.,
H. M. Ozone Practitioners Organization of Malaysia
200 West 57th Street, New York, New York, 10019
(O)212-581-0101 (C) 516-967-1009
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What if there was a safe, effective and proven
treatment for just about every disease?
What if it had been successfully used for over 70
years all over the world?
What if there were hundreds of medical papers
written about it?
What if there were thousands of doctors, clinics and
hospitals worldwide using this therapy everyday?
What if hundreds of thousands of patients with
AIDS, Hepatitis C, Arthritis ,Herpes, MS and a host
of many other diseases used this therapy with
success?
You would have heard
about it, right?
Well, guess what? There is such a
therapy but because of the blackout
in the news you may not know it
exists and you don’t know it works
safely?
WHY?
$$$$ IT IS LOW COST $$$$
$$$$ IT IS NOT PATENTABLE $$$$
THUS, NO MONEY IN IT FOR THE
PHARMACEUTICAL COMPANIES!
FOLLOW THE MONEY
TRAIL!
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When ozone enters the body it acts like “glue” to
toxins, toxic metals and harmful free radicles allowing
the body to remove them.
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Simply, being electron deficient, it steals an electron
from bacteria, virus, fungus, yeast and mold cells
destroying them. Organisms cannot mutate into a
strain that cannot be destroyed. Cuts through bio-film.
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It has many benefits to the blood and circulation and
energy production.
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In concentrations of 50-55mcg’s (gamma) it causes the
greatest increase in production of alpha and beta
interferon; interleukin-2,6,7,8 and TNF
What does ozone do?
Major
AutoHemotherapy(with/without
Hyperbaric) (MAH)(45,000)
 Direct Intravenous Ozone
(DIV)(140,000)
 EBOO/ Alif 1 EBOO SAFE (Simple
Access Fluid Extraction)/
Aquaphersis
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Most Effective Methods of
Administration
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Glucose-6-Phosphate-Dehydrogenase
Insufficiency
Ozone Allergy
Recent Myocardial Infarction
Active Hyperthyroidism
Thrombocytopenia
Pregnancy
Contraindications
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In my practice only two patients in over
140,000+
DIV
therapies
developed
a
“temporary rash” within 30 minutes of a
treatment, two treatments in a row after 30-40
treatments!
Jacobs,M.T.,
1982,
Untersuchung
uber
Zwischenfalle und typische Komplikationen in
der Ozon-Sauerstoff-Therapie, OzoNachrichten
1:5
Study in Germany, 644 therapists
surveyed, 384,775 patients, 5,579,238 treatments
(over two years),only 40 cases of adverse
reactions, a rate of .0007%!
Adverse Reactions
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Direct IV puts an oxygen/ozone gas mixture
directly into the veins at a set concentration.
Concentration used is from 14 to 55 mcg/cc
(gamma) (1% O3 @ 14mcg’s to 3.95% @ 55mcg’s)
Volume of gas delivered is from 5 to 240cc at a
rate of 1cc every 5 seconds or slower.
Creates high levels of ROS and LOP’s in blood
DIRECT IV
“There have been deaths from DIV”
“It causes oxygen lung embolisms”
“It creates harmful free radicals”
“It damages veins”
Medical “Urban Myth”
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Hair and nails grow longer, stronger, healthier
and faster.
Skin becomes healthy.
Fall asleep easier, sleep better and need less
sleep.
More energy all day long.
Increases blood circulation and tissue
oxygenation.
Greater endurance during athletic training.
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SLOWS THE AGING PROCESS DOWN!
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Side Effects
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Precise dosage
Less medical waste; simple syringes used
Stimulates Increase of anti-oxident enzymes in healthy cells
Removes unwanted antibodies ( sero-conversion) and harmful free radicals
from blood
Small (27g) needles used, veins saved
Allows for use of smaller veins, more patients eligible
No need for Heparin
Creates LOP’s and ROS’s in blood in large amounts
Stimulates the body to make large amounts of Interferon and Interlukens
(2,6,7,8 and TNF)
Crosses blood brain barrier
Chelates toxic metals off nerve tissue
Removes plaque from arteries
Takes only 1 to 12 minutes to complete
Allows two treatments per day/6 days a week
Lower cost to patient with faster results
Cuts through bio-film
Benefits of Direct IV over
MAH
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Blood is treated ex vivo similar to a classical
dialysis system with oxygen-ozone flowing in
the opposite direction and the blood being
filtered through a special filter system
Takes about one-two hours
Ozonates all the blood several times per session
NO ozone enters the body
Does react with gluathione in the blood
creating ROS’s and LOP’s
Performed only once per week
EBOO- EXTRACORPOREAL
BLOOD OXYGENATION &
OZONATION
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Many functions including elimination of excess
body fluid (edema)
Sterilization of entire blood supply several times per
hour
Takes 1 ½ hours, done once a week
Cleanses entire blood supply of ALL impurities
including cholesterol
Removes all waste as well as any off gassing in an
enclosed system
Little to no ozone enters the body
Must have good veins or PIC line
Reduces size of heart while increasing cardiac
output
Alif 1 EBOO SAFE by
CHF Solutions, Inc.
EBOO
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Rectal Insuflation
Vaginal Insuflation
Prolotherapy-Prolozone
Drinking ozonated water
Direct injections into tissues
Ozone sauna-vinyl exercise suit
WARNING!
NEVER INHALE OZONE IN HIGH
CONCENTRATION
Other theraputic methods
of using Ozone
All viral, bacterial and fungal diseases and
infections:
Measles; Herpes (all forms); Lyme; AIDS; Acne;
Hepatitis A, B, C; Gangrene; Flu; Rhinovirus;
Candidiasis; Tinea; C. dif.; E. coli; Krohn’s;
Pneumonia; Polio; Warts; Stealth viruses
(echovirus); Shingles (post-herpetic pain);
Protozoal infections of all kinds.
 Bells palsy; MS; ALS (Viral?)
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Some Diseases-Conditions
Treated with Ozone
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All auto-immune diseases:
RA; Lupus; Scleroderma
RSD/CRPS
Burns
Parkinson’s; Alzheimer disease
ASO; Atherosclerosis
Diabetic neuropathy; retinopathy; ulcers
Allergies/asthma
Glaucoma; Macular degeneration; Conjuctivitis (all
forms)
Anything with “itis” at the end of it
Psoriasis; most every skin conditions
Some Diseases-Conditions
Treated with Ozone
STUDIES?
STUDIES?
SHOW ME SOME
STUDIES!!!
Probl Tuberk Bolezn Legk. 2009;(3):28-33.
[Ozone therapy for protracted pneumonias].
[Article in Russian]
Belianin II, Shmelev EI.
Ozone therapy for protracted pneumonias
substantially enhances the efficiency of antibiotic
treatment.
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PubMed- Examples of the
Scientific Study of Ozone
Therapy
Patol Fiziol Eksp Ter. 2008 Oct-Dec;(4):23-5.
[Pathophysiological aspects of endotoxicosis
complicated with purulent infection of the foot
and
correction
of
endotoxicosis
with
conventional treatment and with application of
ozonized physiological solution in patients
suffering from diabetes mellitus].
[Article in Russian]
Gazin IK.
While the conventional therapy reduces
endogenous intoxication, intensity of lipid
peroxidation, ozonotherapy produces a prompt
and effective decrease in pathological activity of
lipid peroxidation, regulates a dynamic balance
between pro- and antioxidant systems of the
human body and, finally, reduces endotoxicosis
severity in diabetic patients.
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J Laryngol Otol. 2009 Jan;123(1):54-60. Epub
2008 Oct 17.
Randomised,
double-blinded,
placebocontrolled, clinical trial of ozone therapy as
treatment of sudden sensorineural hearing loss.
Ragab A, Shreef E, Behiry E, Zalat S, Noaman M.
Department of ORL Head and Neck Surgery,
Menofia University Hospital, Egypt
Ozone therapy is a significant modality for
treatment of sudden sensorineural hearing loss;
no complications were observed
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[Combined treatment including ozonotherapy
of patients with viral hepatitis ].
[Article in Russian]
Chernyshev AL, Filimonov RM, Karasev AV,
Neronov VA, Maksimov VA.
Vopr Kurortol Fizioter Lech Fiz Kult. 2008 MayJun;(3):19-22.
…with the purpose to correct of disturbances of
hepatic exocrine function in patients with viral
hepatitis and to prevent stone formation, it is
reasonable to use together with antiviral therapy
also
intravenous
injection
of
ozonated
physiological solution and preparations of
ursodeoxycholic acid.
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Vestn Ross Akad Med Nauk. 2008;(4):27-34.
[Conservative methods in the therapy of male
sterility. Critical analysis].
[Article in Russian]
Artiukhin AA
After 2-3 courses (with intervals of 3 months)
positive dynamics was observed in almost 70%
cases. Thus, general ozonotherapy should be
considered as one of effective technologies of
treatment in patients with male sterility.
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Nan Fang Yi Ke Da Xue Xue Bao. 2007
Mar;27(3):384-6.
[Percutaneous intradiscal oxygen-ozone
injection for lumbar disc herniation: no need of
perioperative antibiotic prophylaxis].
[Article in Chinese]
Wei CJ, Li YH, Chen Y, Wang JY, Zeng QL, Zhao
JB, Mei QL.
Department of Interventional Radiology, Nanfang
Hospital, Southern Medical University,
Guangzhou 510515, China. wcjun1999 @163.com
Prophylaxis antibiotics is not necessary during
the perioperative period of percutaneous
intradiscal ozone injection for lumbar disc
herniation.
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Vopr Kurortol Fizioter Lech Fiz Kult. 2006 NovDec;(6):34-7.
[Ozone therapy in gastroduodenal pathology
associated with Helicobacter pylori]
Fedorov AA, Gromov AS, Sapronenok SV,
Kurochkin VIu, Zhernakova ZM.
All the techniques of ozone therapy proved
effective in relation to regress of clinical
symptoms, regeneration processes, eradication of
Helicobacter pylori, but the combined regimen
was the best.
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J Craniofac Surg. 2006 Nov;17(6):1080-3.
New therapeutic protocol in the treatment of
avascular necrosis of the jaws.
Agrillo A, Petrucci MT, Tedaldi M, Mustazza MC,
Marino SM, Gallucci C, Iannetti G.
Department of Maxillo-Facial Surgery, University
of Rome "La Sapienza," Policlinico Umberto I,
Rome, Italy.
An analysis of the international medical literature
shows that surgical treatment of the necrotic jaws
in patients treated with bisphosphonates has
proven to be ineffective in stopping the
pathological process. The use of hyperbaric
oxygen and antibiotics are not effective, either.
The authors have developed a new protocol for
the management of these lesions. Compared with
other therapeutic choices, this protocol has
introduced the use of ozone therapy as
therapeutic support.
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Int J Artif Organs. 2005 Oct;28(10):1039-50.
Extracorporeal blood oxygenation and
ozonation (EBOO): a controlled trial in patients
with peripheral artery disease.
Di Paolo N, Bocci V, Salvo DP, Palasciano G,
Biagioli M, Meini S, Galli F, Ciari I, Maccari F,
Cappelletti F, Di Paolo M, Gaggiotti E.
Nephrology and Dialysis Department, University
Hospital of Siena, Siena—Italy
EBOO was much more effective than prostacyclin
for treating skin lesions in PAD patients and also
had a positive effect on patient general condition
without any apparent change in arterial
circulation. This suggests other mechanisms of
action of EBOO.
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Med Sci Monit. 2002 Jul;8(7):CR520-5.
Ozone therapy and the activity of selected
lysosomal enzymes in blood serum of patients
with lower limb ischaemia associated with
obliterative atheromatosis.
Tafil-Klawe M, Woźniak A, Drewa T, Ponikowska
I, Drewa J, Drewa G, Włodarczyk K, Olszewska
D, Klawe J, Kozłowska R.
Department of Physiology, L. Rydygier Medical
University in Bydgoszcz, Poland
Ozone therapy administered by intravenous
infusions and aerosol oxygen-ozone baths of
lower extremities yields much better therapeutic
results in comparison with classical balneology.
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Zh Nevrol Psikhiatr Im S S Korsakova.
2000;100(11):35-7.
[Ozone therapy of migraine].
[Article in Russian]
Kotov SA.
In 58% of the patients the attacks were absent
during 3-5 months after ozone therapy; less
intensity of headache was observed after their
relapse. Improvements in the patients coincides
with changes in biochemical parameters.
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Panminerva Med. 1995 Sep;37(3):129-32.
Effects of ozonized autohaemotherapy on
human hair cycle.
Riva Sanseverino E, Castellacci P, Misciali C,
Borrello P, Venturo N.
Institute of Human Physiology, University of
Bologna, Italy.
The dosage of ozone was 2500-3000 micrograms
for each treatment, one cycle consisting of 16
treatments.
Results
showed
a
marked
improvement of the hair cycle.
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Br J Biomed Sci. 2007;64(1):44-9.
The case Department of Physiology, University of
Siena, via Moro 2, 53100, Siena, Ital
Ozone is a very reactive gas that is toxic to the
respiratory system. However, under controlled
conditions, it can be therapeutically useful in several
human diseases. An unfavourable combination of
factors (ozone is one of the worst troposphere
pollutants) and past misuse have led to misgivings
about ozonetherapy. However, basic and clinical work
developed over the past 10 years has clarified the
fundamental mechanisms of action of ozone in biology
and medicine. Interestingly, judicious doses of ozone
dissolved in blood trigger a cascade of well-defined
chemical compounds acting on multiple cellular
targets
according
to
well-known
molecular,
biochemical
and
pharmacological
pathways.
Ozonetherapy is proving to be very useful in agerelated macular degeneration, ischaemic and infectious
diseases, and in wound healing disorders, where
conventional medicine has failed. Critical evaluation of
the potential therapeutic utility of this simple,
inexpensive medical application by national and
international health authorities is warranted and may
lead to clinical benefit for a large proportion of the
world's population.
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Mediators Inflamm. 2004 Feb;13(1):3-11.
Ozone as Janus: this controversial gas can be either
toxic or medically useful.
Bocci V.
Department of Physiology, University of Siena, Italy.
Ozone is an intrinsically toxic gas and its hazardous
employment has led to a poor consideration of ozone
therapy. The aim of this review is to indicate that a
wrong dogma and several misconceptions thwart
progress: in reality, properly performed ozone therapy,
carried out by expert physicians, can be very useful
when orthodox medicine appears inadequate. The
unbelievable versatility of ozone therapy is due to the
cascade of ozone-derived compounds able to act on
several targets leading to a multifactorial correction of a
pathological state. During the past decade, contrary to
all expectations, it has been demonstrated that the
judicious application of ozone in chronic infectious
diseases, vasculopathies, orthopedics and even dentistry
has yielded such striking results that it is deplorable that
the medical establishment continues to ignore ozone
therapy
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Aging
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As people age, their bodies bodies extract oxygen
and transport it to cells LESS efficiently.
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The cumulative effect of this lack of O2 is:
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A decrease in the flow of nutrients to the cells
Impairment of creation of necessary cell energy
Impairment of necessary cellular chemical reactions
Cells die prematurely
Appearance of disease
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•
Aging
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By inactivating and/or destroying all viruses,
bacteria, fungus, yeast and mold
By eliminating all harmful free radicals
By eliminating all toxic metals
By destroying all tumors
By increasing oxygenation of cells and creating
necessary cellular energy
Anti-Aging Benefits: Reduces
“STRESS” on the Body
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Clumping of Red Blood cells is reduced or
eliminated
Increase flexibility of Red Blood cells
Makes Red Blood cells rounder
Increases Oxygen carrying ability
Oxygenation of tissues increases as the arterial
partial pressure increases
Viscosity of blood decreases
Oxidizes the plaque in arteries
Anti-Aging Benefits:
Benefits to Circulation
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Causes increase in Red Blood cell glycolysis
rate
leading
to
stimulation
of
2,3diphosphoglycerate
This shifts the oxyhemoglobin disassociation
curve to the right
Which leads to increase in amount of O2
released to cells
Anti-Aging Benefits:
Stimulates O2 Metabolism
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Ozone stimulates the production of antioxidant enzymes: Glutathione peroxidase,
Superoxide desmutase, Catalase and Reductase
which:
Protect healthy cells from damage by ozone
Acts as free radical scavengers reducing stress
Ozone activates the Krebs Cycle by enhancing
oxidative decarboxylation of pyruvate thus
stimulating production of ATP’s
Anti-Aging Benefits:
Cell protection and Energy
production
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Ozone reacts with polyunsaturated fatty acids of the
lipid layer in cellular membranes forming various
peroxides (ROS’s)
Lipid Peroxidation: One of the two main processes
whereby one mole of Ozone and one mole of an
olefin (particularly arachidonic acid present in
plasma triglycerides) create one mole of H2O2 and
two moles of aldehyde (Pryor et. al., 1995)
This creates a number of different aldheydes known
as Lipid Oxidation Products (LOP’s)
Most of Ozone’s reactions/benefits are due to the
ROS’s and LOP’s which are created instantly as
ozone dissolves in the lymph in blood
FORMATION OF ROS’S
and LOP’s
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Cells need energy to stay alive and perform their
purpose
Healthy cells make energy via the Krebs Cycle
They need oxygen and nutrients to make energy
They need a delivery system to bring it
They need a waste removal system
“OZONE’S BENFITS DELIVERS ALL
OF THE ABOVE EXTENDING CELL
LIFE
AND
FUNCTION
THUS
RETARDING THE AGING PROCESS!”
Why this is so Important
to Anti-Aging
Aging is a necessary process.
The “trick” is to GROW OLD AND BE
WELL and to be able to function on a
high level.
THIS IS WHAT CAREFULLY
PERFORMED OZONE THERAPY CAN
HELP DELIVER!
When you combine the cleansing,
detoxification
and
immune
boosting benefits of Intravenous
Ozone Therapy, along with a
program
of
healthy
cardiovascular
exercise
and
healthy nutrition, it is possible to
significantly slow the aging
process.
IN SUMMARY
“When one considers the
alternative to growing
old…”
THANK YOU FOR YOUR
KIND ATTENTION!
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