Bacterial pneumonia (Streptococcus pneumoniae)

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Zachary Rushton
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Inflammatory condition of the lung affecting
the alveoli especially
Most common infectious agent leading to
hospitalization in the world
http://www.nlm.nih.gov/medlineplus/ency/images/ency/fullsize/19680.jpg
http://textbookofbacteriology.net/PHILspbloodGram.jpg
http://pathmicro.med.sc.edu/fox/strep-pneu_small1.jpg
http://www.nature.com/nrmicro/journal/v6/n4/images/nrmicr
o1871-f2.jpg
http://worldpneumoniaday.org/learn/2011-progress-report/
http://cid.oxfordjournals.org/content/51/9/1042/F1.medium.g
if
http://www.microbiologyinpictures.com/bacteria%20photos/str
eptococcus%20pneumoniae%20photos/streptococcus%20pneum
oniae%20027.jpg
http://www.thailabonline.com/bacteria6streppneumo.htm
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neumoniae_meningitis%2C_gross_pathology_33_lores.jpg/402pxStreptococcus_pneumoniae_meningitis%2C_gross_pathology_33_lores.jpg
http://practicalhospital.com/wpcontent/uploads/2011/07/c7_nasopharynx-297x300.jpg
http://www.thailabonline.com/bacteria6streppneumo.htm
White blood cell
pneumolysin
http://funwithgovernment.blogspot.com/2011/03/killer-diseases-inphilippines.html
http://www.nlm.nih.gov/medlineplus/ency/imagepages/19680.htm
http://www.nlm.nih.gov/medlineplus/ency/imagepages/19680.htm
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Penicillin resistance has led to increase in
mortality rate
◦ Penicillin- nonsusceptible  19.4%
◦ Susceptible  15.7%
◦ Production of altered penicillin binding proteins
http://sciencenaturalphenomena.blogspot.com/2009/04/cephalosporins.html
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There currently exists a 23 valent capsular
polysaccharide vaccine
Based on knowledge that antibodies formed
against the capsule are very effective in
preventing lethal S. pneumoniae infection
1 shot
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5 years later, a
booster is given
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