UNVEILLING OF ISAAC FOLORUNSO ADEWOLE FOUNDATION (IFAF) Professor Oladapo A. Ladipo, OON COMPLIMENTS The Organisers The Celebrant Isaac Folorunso Adewole, FAS Why is this Foundation imperative? In Nigeria, we have made modest improvement in improvement of the health of our women but access has not been universal. Majority of women suffer untold hardships as well as myriads of health and social challenges, which either cause ill health or premature death. Our reproductive health indicators, which are poor, remain a significant indicator of our state of national development. Global mortality per annum of Cervical Cancer • • • Worldwide, every 2 minutes a woman dies of cervical cancer1 The highest burden of disease (up to 80%) occurs in less developed regions2 where there is a lack of effective screening programmes This demonstrates a clear medical need for new cervical cancer interventions Northern America > 12,000 new cases > 4,000 deaths Europe > 54,000 new cases > 25,000 deaths Asia > 312,000 new cases > 159,000 deaths Latin America > 67,000 new cases > 31,000 deaths Africa > 80,000 new cases > 53,000 deaths Cervical cancer mortality rates worldwide 1. Ferlay J, et al. GLOBOCAN 2008, Cancer Incidence and Mortality Worldwide. IARC CancerBase No.10; Lyon, France, 2010; 2. Kitchener HC, et al. Vaccine 2006; 24(Suppl 3):S63–S70. Cervical Cancer needs Attention! Cervical cancer is the second commonest cause of cancer deaths in among Nigeria women. About 70% of the 14,000 women who develop cervical cancer every year die from the disease. These unacceptable fatalities are due to Ignorance about the cause, Poor health seeking behaviour Lack of access to and use of effective preventive services Weak treatment facilities and poverty. Progression of cervical disease Progression* Normal epithelium Years Months Time HPV infection koilocytosis CIN1 Low-grade squamous intraepithelial lesion (ASCUS/LSIL) CIN2 CIN3 Invasive carcinoma High-grade squamous intraepithelial lesion (HSIL) Regression * With increasing probability of viral DNA integration. CIN = cervical intraepithelial neoplasia; ASCUS = atypical squamous cells of undetermined significance. Burd EM. Clin Microbiol Rev 2003; 16:1–17; Solomon D, et al. JAMA 2002; 287:2114–2119. Continuum of Care for Cervical Cancer Control 15 years Vaccination Source: WHO 2006 7 30 years Screening and treatment 45 years Cancer treatment IFAF is non-profit philanthropic organisation The need to improve on the health of our women that is often neglected remains the driver of the passion of Isaac Folorunsho Adewole who decided to establish a non-profit philanthropic initiative, Isaac Folorunsho Adewole Foundation (IFAF). The IFAF Concept The Isaac Folorunsho Adewole Foundation (IFAF) was conceived to offer high quality humane and selfless services in area of Advocacy Development of accessible cervical cancer prevention programmes Capacity building for young and committed medical faculty/other allied professionals Networking and linkages as well as partnering with other interest groups to promote health of women at national and international level. IFAF aims to translates despair to hope! Strategic intervention of IFAF to prevent CC Behavioural Change Communication Operational Research to generate better policy Community based prevention programmes – (Human papilloma virus vaccine demonstration project; Community Screening Model, and Treatment of pre-cancer stages) Linkage, treatment and control of invasive cervical cancer cases Technical support on Cervical Cancer Policy formulation Capacity building for frontline workers Resource mobilization and networking Programme monitoring and evaluation Membership of Trustees 1. 2. 3. 4. 5. 6. 7. 8. Prof O.A. Ladipo OON - Chairman Prof I.F. Adewole FAS Justice Pat Mahmoud Mrs Ngozi Iwere Dr Adeola Adewole Dr Adebayo Jimoh Prof Funmi Togonu-Bickersteth Director- Dr Adeola Adewole How can IFAF be reached and supported? Web address www.ifaf.org.ng The Unveiling Moment To the Glory of Almighty, It is my pleasure to unveil the Isaac Adewole Folorunso Foundation focusing on Women Health with specific attention on Cervical Cancer Prevention and management programmes It is my hope and fervent prayers that IFAF shall prosper in her dealings with humanity. Let us all support this initiative with our resources! Thank you for Listening