Dila-Pro The World’s First Smart Cervical Dilator Benjamin Lee, CEO Anne Kwei, CTO Matthew Lee, CMO/CRO Grace Shih, CFO Clark T. Hung, Ph.D. Rachel Masch, M.D., M.P.H. The Problem 500,000 manual cervical dilation procedures annually in the US Current Dilators Uncontrollable Dilation Rate Insufficient Dilation Lacks PatientTailored Specifications Inadvertent Induction of Labor No Established Protocols Extreme Patient Discomfort Tissue Damage Company Overview Our Advantages Mission Nothe major competition To• be pioneers of the next-generation of cervical dilation technology • Among the first to address this problem • Access to first-rate equipment Our• Vision Mentorship of expert advisors To design an innovative and cost-effective cervical dilator that uses advanced, smart technology with an emphasis on patient needs Market $200 million cervical dilation market per year 25%: ~$50 million cervical dilators Dilation Features Current Products Cervix Dilation Cost Effective One Insertion Application Applicability to All Procedures Comfortable and Tailored Dilation Preservation of Cervical Integrity Our Product Dila-Pro The World’s First Smart Cervical Dilator portable and discreet safe and efficient patient tailored Prototype Design Prototype Testing Costs • Prototype production and testing is made possible by a $500 sponsorship from Columbia University Department of Biomedical Engineering • The bulk will be spent on component purchases: Component Balloon Pressure Gauge Supplier Advanced Polymers Honeywell Sensing and Control, 0-100 PSI Freescale Semiconductor, 0-101.5 PSI Air Pump Hargraves Mini Air Pump, 28 psi Syringe pump, borrow from undergraduate lab Check Valve Fisher Scientific Tubing Borrow from undergraduate lab Data Borrow from undergraduate lab Acquisition Computer Borrow from undergraduate lab Phantom Inflatable cuff, from undergrad lab Air pump, from undergrad lab Quantity Price Total Each 10 $18.00 $180.00 2 $32.09 $64.18 3 1 1 $15.84 - $47.52 $85.00 - 6 10 ft 1 $5.29 - $31.75 - 1 1 1 Total: $408.45 Business Model Phase 11 Phase Develop a final marketable version of DilaPro Phase 2 Phase 3 Phase 4 In Vivo Testing of Dila-Pro Launch Dila-Pro Improve and update Dila-Pro FDA Approval Application Market to physicians Establish relationships with clinics and hospitals Maintain strong relationship with customers Financial Outlook $2,000 $30 • ‘Trade-In’ for $500 • Devote funds to R&D and advertising • ~50% of the market and second product release by 2017 Website Acknowledgements Dr. Clark Hung Professor of Biomedical Engineering Dr. Elizabeth Hillman Assistant Professor of Biomedical Engineering Dr. Rachel Masch Associate Director of Family Planning, Beth Israel Hospital Dr. Rujin Ju Beth Israel Hospital Keith Yeager Senior Staff Associate, Laboratory Manager Lauren Grosberg Graduate Student in Biomedical Engineering Cost-Effectiveness We expect each device to be used approximately 5 times per week (5 times/week) x (52 weeks/year) x 2 years = 520 device usages $2000 per unit/520 usages = $3.84/usage $4 + $30 (disposable components) = $34, the total cost per usage of Dila-Pro Comparable to the cost of current dilators Patient Physiologies Myers, K. M.; Paskaleva, A. P.; House, M.; Socrate, S., Mechanical and biochemical properties of human cervical tissue. Acta Biomater 2008, 4 (