„BioCon Valley – the Cluster in Life Science and Health, Mecklenburg-Vorpommern, Germany“ Kasan, April 24th, 2013 Dr. Heinrich Cuypers, Senior Project Manager BioCon Valley Impact of Life Science – Woman in the Age of 63 e.g. Sophia Loren (1997) Dürers Mother (1514) …and it is a big market too ! …because of - modern medicine - healthy nutrition - clean environment © BioCon Valley® GmbH · Greifswald / Rostock Definition Biotechnology Cluster Critical factors for development* 1. 2. 3. 4. 5. 6. 7. Strong science base (R&D) Entrepreneurial culture Growing company base Ability to attract key staff Availability of finance Premises and infrastructure (e.g. Bioincubators) Business support services and large companies in related industries 8. Skilled workforce 9. Effective networks 10. Supportive policy environment *source: “BIOTECHNOLOGY CLUSTERS”, Report of a team led by Lord Sainsbury, Minister for Science UK, August 1999; http://www.dti.gov.uk/biotechclusters/ © BioCon Valley® GmbH · Greifswald / Rostock German BioRegions: hot spots for biotech industry since 1996 13.04.2015 © BioCon Valley® GmbH · Greifswald / Rostock 4 Biotech in Germany – catching up e.g.: No of new drugs in development („pipeline“), clinical phase I – III Figure a: 2001 UK 128 Dänemark Schweiz 20 Frankreich 19 Schweden 18 Israel UK 7 Deutschland 6 Finnland 5 Niederlande 5 218 Deutsch… 142 Dänemark 14 Italien Andere Figure b: 2011 28 125 Frankreich 118 Schweiz 121 Schweden 82 Israel 28 61 Italien 79 Niederla… Finnland Source: Ernst & Young 36 21 © BioCon Valley® GmbH · Greifswald / Rostock Health Economy in MV – key figures • • • • • Number of employees ~ 97.500 Gross value added ~ 4 bio. € > 120 life sciences companies (biotech, medtech, pharma) 2 universities with focus on life sciences and health (2 univ. hospitals) 3 universities of applied sciences, 5 federal or regional research institutes, > 20 centres of competence • More than 60 modern hospitals and rehabilitation clinics (> 12.000 beds) • Tradition in spa and wellness tourism with – more than 255 star rated hotels and spas (> 50% 4 star +) – 54 audited health and recreation resorts („Kurort“) • Regional agenda (Masterplan) for Health Economy • Kuratorium Gesundheitswirtschaft (appointed by prime minister) © BioCon Valley® GmbH · Greifswald / Rostock 6 Masterplan Gesundheitswirtschaft 2020 A Vision for Mecklenburg-Vorpommern in 2020 Health Services Health Tourism Life Sciences Health Care Primary sector 10 year strategic agenda Projects focussing on cross-sectoral approaches Kuratorium as „triple-helix“ advisory body Healthy Ageing © BioCon Valley® GmbH · Greifswald / Rostock Healthy Food 7 BioCon Valley: The Region Rostock Schwerin Greifswald Copenhagen Northern Germany Population ca. 1,8 Mio. (= Hamburg) Size ca. 23.000 km² Ca. 80 inhabitants / km² Rostock biggest city (200.000 inhabitants) > 1.000 km coastline Challenges Potentials Казан Berlin • Rural area & development Economical focus - Strong research • Low industrialization • Maritime industry - Dynamic enterprises (SME) (low infrastructure GDP, no „big“• Agriculture - Modern enterprises, ...) hospitals) • Tourism (technology centers, • Remote location (in • Life Sciences - Active network Germany)platform • Health Care - International © BioCon Valley GmbH · Greifswald / Rostock ® Research and Development Rostock • approx 3.000 employees in R&D Greifswald • approx. 6.430 students (total approx. 38.000) • approx. 90 Mio. € p.a. in life sciences R&D Research and development in Life Sciences at - 2 universities (Rostock 1419, Greifswald 1456) - 3 universities of applied science - 5 non universitary federal or regional research institutions - 16 more centers of competence within life sciences e.g. Universität Rostock e.g. Universität Greifswald e.g. Fachhochschule Stralsund e.g. Fachhochschule Neubrandenburg © BioCon Valley® GmbH · Greifswald / Rostock Core Competences in R&D Marine Biotechnology Medical Biotechnology - Screening for new bioactive compounds - Aquaculture - „FunGene“ - Agrobiotechnology Other Biotechnologies - Plant development, plant breeding - Animal health, animal breeding - Molecular Medicine Regenerative Medicine Medical Technology Telemedicine Life Science Automation Bioanalytics Bioinformatics Food applications © BioCon Valley® GmbH · Greifswald / Rostock Case Studies – Applied Research, e.g. • „BIOKATALYSE2021 Novel approaches to a sustainable industrial «white» biotechnology” (2007-2012); www.biokatalyse2021.de • „PHENOMICS – Network of Competence of Agricultural and Nutritional Research on Farm Animals“ (2010-2015) www.phaenomics.auf.uni-rostock.de • „HICARE – Alliance against Mulit-resistant Bacteria: National Health Region Baltic Sea Coast“ (2011-2015) http://hicare.de • „CELISCA – Center for Life Science Automation“ (2012-2017) www.celisca.de/ • „REMEDIS – The implant technology of the future” (2009-2013) http://remedis.med.uni-rostock.de/ • „GANI_MED – Greifswald Approach to Individualized Medicine” (2009-2013) www.medizin.uni-greifswald.de/gani_med > Complete Mapping: CD-ROM based BioCon Valley® - directory, 8th ed 2011 © BioCon Valley® GmbH · Greifswald / Rostock Case Studies – Companies, e.g. • Cortronik GmbH & Co KG, 180 jobs www.cortronik.de biocompatible implants (“stents”) • DECODON GmbH, Greifswald, 12 jobs www.decodon.com bioinformatic for functional genomics • DOT GmbH, 235 Jobs www.dot-coating.de coating implants, reg.med. (orthopedic) • Miltenyi Biotec GmbH, TET, 180 jobs www.miltenyibiotech.de enabling technologies, cell charact. & isolation • DST GmbH www.dst.com fast allergy test systems (pats, cattle, dust, nutrition ingredients, • NPZ Saatzucht Hans Lembke KG, 170 jobs plant breeder (canola, clover) www.npz.de • Riemser Arzneimittel AG, 650 jobs pharma (cancer, derma, vet.) www.riemser.de > Complete Mapping: CD-ROM based BioCon Valley® - directory, 8th ed 2011: © BioCon Valley® GmbH · Greifswald / Rostock Biotech Incubators and Parks Biotech incubators BioTechnikum Greifswald (2) Hamburg Rostock A20 Teterow Greifswald Neubrandenburg A19 Forschungszentrum Biosystemtechnik und Biomaterialien (1) Biomedizinisches Forschungszentrum Zentrum für Lebensmitteltechnologie A24 AgroBioTechnikum Groß Lüsewitz (4) Berlin Biotech park Biomedizin-Technikum Teterow (3) 1 2 3 4 Enterprises, Life Science Formation of companies . First phase 92/93 . Second Phase 97/00 140 4000 3500 3000 2500 2000 1500 1000 500 0 120 100 80 60 40 20 No. of companies 20 12 20 10 20 08 20 06 20 04 20 02 20 00 0 19 97 No. of companies . Envitec GmbH . Gambro Rostock GmbH . Hoffrichter . Miltenyi Biotec GmbH . Riemser Arzneimittel AG No. of jobs No. of jobs 120 Enterprises ~ 3.600 Employees Medium sized companies, e.g. . DOT GmbH Multilayer model Source: PD Dr. J. Hilbert, IAT Gelsenkirchen Health Economy Core sector Inpatient and outpatient treatment Secondary sector (Administration,pharmacies, Spa and rehabilitation, patient organisations) Health care related industries (Bio-/Medtech, Pharma, Handicraft, …) Related and neighbouring sectors (sports, tourism and others) MV Employees 97.500 Gross value added (Mrd. €) © BioCon Valley® GmbH · Greifswald / Rostock ~ 3,5 – 4,0 15 BioCon Valley® GmbH – cluster management Tasks: – – – Bundle and align regional interests and forcees in life sciences and health (triple helix-model) Stimulate cooperation between companies, research & development and health care providers Foster international marketing and collaboration Shareholders: – – – Federal State Mecklenburg-Vorpommern BioCon Valley Mecklenburg-Vorpommern e.V. (~160 members) 4 financial institutions, 2 private shareholders 2 locations (Greifswald and Rostock) with presently 20+ employees © BioCon Valley® GmbH · Greifswald / Rostock 16 Networking national & international National: BioCon Valley is member of the German BioRegions; www.biodeutschland.org/ak-bioregio.html www.biotechnologie.de International: BioCon Valley is cofounder of ScanBalt – the network of Life Science and health networks in Northern Europe, i.e. Denmark, Estonia, Finland, Iceland, Latvia, Lithuania, Norway, Poland, Sweden, North-West Russia; www.scanbalt.org 13.04.2015 17 Projects Communication and Visibility www.scanbalt.org and ScanBalt News Regional Portraits Industry Opinions Meetings, partnering, events Ongoing strategy discussion Competence mapping and cluster analysis Strategic communication Strategic partnerships Creating Infrastructure ScanBalt Health Region (EU flagship) Eco4Life (EU) ScanBalt Campus (EU ScanBalt Network of Networks (Nordic Inno Centre) ScanBalt Competence Region (EU) Boosting Baltic FP6 (EU) Educational mobility (Nordic Inno Centre) Economic Barriers for Borderless Cooperation (Nordic Inno Centre) Biotech, one click away (Nordic Inno Centre) Thematic Focus BSHR Healthport (EU) Submariner (EU) Baltic Amber (DLR) ScanBalt IP-Knowledge Center (EU) ScanBalt Marine Biotech (NorForsk) ScanBalt Clinical Research Network (Nordic Innovation Centre) ScanBalt AgroBiotech (NorForsk) ScanBalt Stem Cell Network (NorForsk) ScanBalt Biofuel Network (Nordic Innovation Centre) e.g. EU BSR Flagship Project „ScanBalt Health Region“ Set up cross-sectoral reference projects for innovation in health and life sciences Objectives: … promotion of public health on a high level … exploitation of modern health and life sciences … innovations in science, technology and social science Baltic Sea Region as a model for a knowledge-based economy and for implementing a shared strategy Lead Partners: BioCon Valley (Germany) Lithuanian Biotechnology Association (Lithuania) ScanBalt and ScanBalt Academy (ScanBalt BioRegion) More: http://www.balticsea-region-strategy.eu/ www.scanbalt.org Health Economy …some trends Agriculture Source: NY Times, 2008 Source:www.keinfastfood.de Health & Medical Wellness Service oriented industries Source: Der Spiegel, 2008 © BioCon Valley® GmbH · Greifswald / Rostock 21 German-Russian Forum Biotechnology, Rostock 2013 Date: June, 4.-5, 2013 Venue: Rostock, Germany Scope: The German-Russian Cooperation Network Biotechnology aims to deepen, strengthen and to enhance the existing contacts between German and Russian biotechnology companies, research institutions and decision makers in policy and administrations. Day one: workshops (e.g. bioinformatics, industrial biotech, regenerative and personalized medicine, marine biotech) Day two: study tour to companies and research institutes More: http://www.owwz.de/rostock.html 13.04.2015 © BioCon Valley® GmbH · Greifswald / Rostock 22 Thank you for your Attention ! Спасибо! www.bcv.org www.scanbalt.org BioCon Valley® GmbH Walther-Rathenau-Str. 49a D-17489 Greifswald Tel.:+49 3834 515-30 Fax:+49 3834 515-102 Friedrich-Barnewitz-Str. 8 D-18119 Rostock Tel.:+49 381 5196-4953 Fax:+49 381 5196-495