World’s Leading Provider of Turn-key
Compute Solutions for NGS /
Bioinformatics
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Founded in 1989
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Over 1000 PowerWulf Clusters Delivered World Wide
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350+ PowerWulf Clusters Dedicated Compute Appliances for
NGS / Bioinformatics
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Mission Statement
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Tier 1 Manufacturing & Support at Commodity Price
Custom Configured Products Include
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Turn key PowerWulf Compute Clusters
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RaidStation Storage Solutions
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High Performance Workstations & Servers
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Selected by Roche / 454 and CLCbio as OEM Hardware Provider
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Over 60% of ALL WORLDWIDE data off GS FLX Titanium Platform is analyzed on PSSC Labs Platform
Roche’s Success in this space linked directly to PSSC Labs PowerWulf Cluster solution
CLCbio is a leader in genomics software solutions
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Certified our PowerWulf Clusters and Servers Compatible with Life Technologies’ Bioscope &
Illumina’s Casava Applications
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Pacific Biosciences considering PSSC Labs as OEM Hardware Provider
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Recent LARGE Cluster Wins
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Western Kentucky University – 5000+ Cores
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OpenX.org – 7000+ Cores
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MIT / Harvard / HHMI Neuroimaging Center
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PSSC Labs Selected after evaluation of Dell, HP, IBM
PSSC Labs Selected after evaluation of Dell, HP, IBM
Largest GPU Cluster at MIT
Revolutionary POWERSERVE DUO TI2000
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Perfect Cluster Building Block
Tool-Free Design
Power Saving Eco Friendly Features
World Wide Support & Maintenance
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Partnerships w/ leading Sequencing Platform Providers
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Roche / 454
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Life Technologies
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Potential OEM Proider of off line cluster for new RS platform
Ion Torrent
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Certified Cluster / Server Solutions w/ Casava Preconfigured
Pacific Biosciences
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Certified Cluster Solutions w/ Bioscope Preconfigured
Illumina
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OEM Provider of GS FLX Titanium Cluster (www.pssclabs.com/roche)
Certified Workstation w/ Ion Torrent Software
CLC Bio
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Selected as OEM Hardware Provider of Genomics Machine / Factory
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Delivery Fully Functional / Turn Key Systems
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Biologist are typically not system administrators. Just need a
system that works out of the box.
Superior Knowledge & Support
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You will have direct communication with the PSSC Labs Cluster
Engineer that built, tested and configured the system with your
applications.
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Our Remote Assist support provides greater more responsive
support than any other vendor
We Understand Your Business
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Seqwright needs a knowledgeable cost effective hardware provider
that ensures they deliver their customer results on time, every
time.
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Our systems are considered the industry’s most reliable with a failure
rate >0.01%. This is a direct result of our superior testing procedure
 PSSC
Labs Runs Benchmarks Provided by
Application to Certify Systems
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Typical benchmarks include small and large data
sets for all pipeline steps (mapping, assembly,
alignment)
Example
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WT Run is one of three stress tests we run to certify
our clusters for Bioscope
 Results: DURATION= 6 hours 36 minutes 44 secs
 Configuration: 8 Core (2.67 Ghz) / 48GB Memory)
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Information obtained from end users
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Illumina / Casava
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UCI Irvine
 We are sequencing Drosophila (fruity fly) samples. The
genome is approximately 1.2 x 108 base pairs.
 One lane of paired-end, 75bp data from an Illumina GA2
machine gives about 25X coverage of a genome.
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Roughly 35 million pairs of reads per lane or 2* 75 *35e6 = 5.25e10
base pairs of data.
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We sequence 3 lanes per sample. Pipeline involves a lot of
custom software to do our analyses, and we can entirely
process a single sample in about 12 hours. This is much more
than simply doing the alignments
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System Configuration
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PowerServe Duo T2400 (Single SMP System)
8 Processor Cores / 2.4 Ghz
128 GB System Memory
40 TB USABLE High Speed Storage Space
 Information
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obtained from end users
Illumina / Casava
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St. Radbound University
 “Mapping one exome sample to the human reference
takes about 8.5 hours using Bioscope 1.3”
 System Configuration
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PowerWulf Cluster
64 Processor Cores / 2.53 Ghz / 8 Cores Per Node
4 GB Memory Per Core
 CLC
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Bio Genomics Factory Comparison
PSSC Labs is OEM Provider of Genomics Factory
156 Cores (12 cores per node / 2.53 Ghz)
4 GB of Memory Per Core
Stated Performance on Website
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Mapping, whole human genome, 15x coverage: 32 Full
Human Genomes Per Week (2 x 100 basepair Illumina
GA – data
Whole human transcirptome analysis (RNA-seq): 600
Samples per week (130 million 50bp SOLiD reads