EE3080
Design and Innovation Project
Programme:
Electromedical Technologies
Coordinator:
Asst. Prof. Justin Dauwels
jdauwels@ntu.edu.sg
School of Electrical and Electronic
Engineering
Nanyang Technological University
What is Biomedical Engineering?
Biomedical engineering
is a multiple discipline
and high technology
area.
It is to provide
solutions for health
care industries and
services.
ELECTROMEDICAL technologies: electrical engineering applied to healthcare
Electrical Engineers Play a Key Role in
Health Care Industries
Electrical Engineers Play an Key Role in
Health Care Industries and Services
Circuits and electronics
Measurement and instrumentation
Pacemaker
Electrical Engineers Play an Key Role in
Health Care Industries and Services
Information and signal processing
ECG
Medical imaging and image processing
Brain Mapping from EEG
Electrical Engineers Play an Key Role in
Health Care Industries and Services
Modelling and control
Telemedicine
Biomedical Engineering is Exciting
It is important: Health Caring and Life Saving
It is profound and challenging:
Nobel Prizes in Medicine in 1979, for the development of Computed
Tomography (CT) and in 2003 for the development of Magnetic
Resonance Imaging (MRI).
It is High Tech
=
Health Care Industry is Robust and
Resilient in the Economic Crisis
Performance of Different Sectors of NYSE
(2007 – 2013)
1.8
x 10
4
health care sector
energy sector
financial sector
1.6
1.4
1.2
1
0.8
0.6
0.4
0.2
2008
2009
2010
2011
2012
Where do Biomedical Engineers work ?
Research Institutions
Hospitals
Institute of Bioengineering and
Nanotechnology
Bioinformatics Institute
Institute of Molecular and Cell Biology
Defence Medical Research Institute
Bioprocessing Technology Centre
Laboratories for Information Technology
Johns Hopkins Singapore Pte Ltd
SINGAPORE
Academic Institutions/
Government Boards
NTU
Universities
Polytechnics
SGH
NUH
NCC
SNEC
NHC
NNI
Companies
Baxter
Becton Dickinson
Siemens Medical Instruments
Medtronic
GE Medical
Boston Scientific
GlaxoSmithKline
MDS Analytical Technologies
Perkin Elmer
Research at School of EEE on
Electromedical Technologies
microf luidic
channel
Micromanipulator
& optical f iber
f luidic
inlets
Integrated
waveguides
Optical
f iber
f luidic
outlet
Integrated
waveguides
Micromanipulator
Opto- & NanoFluidic Chips
Monolithic PDMS
optofluidic chip
Spectroscopyon-Chip
Microscope-onChip
POC Sensor
Platform
Wearable Respiratory
Monitoring
Lab-on-Chip
nanochannel
Inspired by Clinical Needs
Reputed for Impactful Research
Wireless
Sensing
Elderly Home
Monitoring
microchannel
Quantum Dots
Probe
Telemedicine
Photo-Thermal
Imaging
DCE Imaging
Brain Disorder
Diagnostic
Neuro-Device
Implants
25 Active EEE Faculty Members
Distributed Diagnosis & Home Healthcare (D2H2)
Non-Contact Vital
Sign Biosensors
Home Healthcare Monitoring
or Diagnostic System
Wearable System
Clinics and
Hospitals
Intelligent
Controller
Wherever the patient is..
Handheld
Devices
Smart
Homecare
Monitoring
Prof. Tjin Swee Chuan, et al
Tele-Rehabilitation
Internet
Personal
Health
Information
Management
System
(PHIMS)
Other
Specialist &
Clinicians
Emergency
Room
Primary Care
Provider
Bio-Imaging & Signal Processing
DCE Imaging of Tumor
Microcirculation
Diagnosis/Treatment of
Brain Disorders
Nasopharyngeal Cancer
Diagnosis with optical
Coherence tomography
Collimating
lenses
Mirror
Ti:Sapphire Laser
2x2 fiber
coupler
Reference Arm
Spectrometer
White
light
Probe Arm
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The use of dynamic contrast-enhanced MR imaging (DCE MRI) and dynamic contrastenhanced CT imaging (DCE CT) as a biomarker for anti-angiogenesis therapy
Neuro-electric Engineering for Curing Brain Disorders
Nasopharyngeal Cancer Diagnosis with Optical Coherence Tomography
Fluorescence Life-time Imaging for Medical Diagnosis of Cancerous Tissue
Development of Photo thermal Imaging system for imaging sub-cellular organelles
Processing and Classification of Heart Rate Variability Signals
Bio-Nano Technology and Devices
Micro-fluidic Chips and Devices
Lab on Chip (Nano-Droplet & Bubble Formation)
Outlet
Inlet
Outlet
Formation of hydrogel plug
nanochannel
Inlet
Outlet
nanochannel
microchannel
microchannel
Transformation from plug to spherical droplet
Point-of-Care Biosensor Platform
Microscope on Chip (3D Ultrasound, CMOS
Imager)
+
CMOS Imager
Optofluidic channels
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Nanopattern
fabrication
Integrated
LSPR Chip
LSPR simulation
Multilayer micro-fluidic chip (to form single tumor spheroid), device (for neuron culture)
Lab on Chip (Nano-Droplet and bubble formation) – to mimic blood flow in artery
On-chip total internal reflection (TIR) microscope
Point-of-Care Biosensor platform for screening/diagnosis of cancer & infectious diseases
Microscope on Chip: 3D ultrasound system, CMOS imager near-field System
Major Laboratory Facilities
Cell Culture Room
Research inverted microscope, Incubator, Centrifuge, Water
bath, Ultrapure water system, Ultralow (-80o) freezer,
Cryogenic tank
Biochemical Room
Chemical cabinet, Chemical benches, Chemical hood,
Universal laser cutting system
Dark Room
Optical tables, Lasers,
Supercontinuum light source
Other Equipments
Ultrasound X-Y-Z scanning system, Sonix RP ultrasound system, Medelec Profile
EEG system, Biopac, NORAXON EMG system, Desktop MRI scanning system.
Thanks!
Join this programme to become a leader
in healthcare innovation …
… and improve the quality of life of many patients!
We welcome your ideas!
Professors will soon upload projects.
EE3080
Design and Innovation Project
Programme:
Electromedical Technologies
Coordinator:
Asst. Prof. Justin Dauwels
jdauwels@ntu.edu.sg
School of Electrical and Electronic
Engineering
Nanyang Technological University