Technology Transfer from
the University of Oxford
Las Relaciones Universidad – Empresas:
Un Nuevo Paradigma
Knowledge Based Economy
• Every country in the world wishes to develop the Knowledge Based
Economy.
• The question is asked:
• Where is the Knowledge?
• And the answer in part is inside the universities, and research
institutes, and hospitals.
• And the question then becomes:
• How do we transfer the knowledge out from the research base
into industry to create innovation?
isis-innovation.com
Towers
isis-innovation.com
Making Connections & Doing Business
University technology transfer resource
University
entrepreneurial
culture
isis-innovation.com
Industry,
Business &
Professional
environment
Chalk and Cheese
•
•
•
•
•
Universities and Businesses are very different
A university is not trying to be like a company
A company is not trying to be like a university
Why should Universities want to engage with Businesses?
Why should Business want to engage with University?
isis-innovation.com
University & Business Interactions
• Educated workforce
• Advisory Boards
• Lectures
• Exchanges
• Collaborative Research
• Contract Research
• Donations
• Consulting
• Licensing technology
• Spin-out company formation
• Entrepreneurship
isis-innovation.com
Oxford University
•
Oxford University is the oldest university in the English-speaking world (founded c.1188)
•
A leader in learning, teaching and research
•
26 British Prime Ministers educated at Oxford
•
Including current Prime Minister David Cameron
•
Royal Society founded from Oxford in 1640
•
47 Nobel prize winners
isis-innovation.com
Isis Innovation Ltd
A profitable company 100% owned by the University of Oxford
Oxford Technology Transfer
IP, Patents, Licences, Spin-outs,
Material Sales, Outcome Questionnaires, Seed
Funds, Isis Angels Network, Isis Software
Incubator, Oxford University Hospitals NHS Trust
Oxford Expertise
Consulting, Services
Isis Consulting Business
Technology Transfer and Innovation
Management
@isisinnovation
isis-innovation.com
Isis Innovation, year-ending March 2013
6.0
12
Subvention
Return
5.0
9
4.0
3.0
6
2.0
3
1.0
0.0
0
2001
2004
2007
2010
2001
2013
2004
2007
12
90
80
70
60
50
40
30
20
10
0
2010
2013
Start-Ups
Spin-Outs
10
8
6
4
2
2001
2004
isis-innovation.com
2007
2010
2013
0
2000
2003
2006
2009
2012
Isis Innovation, year-ending March 2013
400
120
350
100
300
80
250
60
200
40
150
20
100
0
2006 2007 2008 2009 2010 2011 2012 2013
2001
120
350
100
300
2004
2007
2010
2013
250
80
200
60
150
40
100
20
50
0
0
2001
2004
isis-innovation.com
2007
2010
2013
2003
2006
2009
2012
Isis helps researchers who wish to
commercialise the results of their
research
isis-innovation.com
Isis Innovation Team
Managing Director
Technology Transfer Group (38)
Tom Hockaday
Linda Naylor
Technology Transfer Teams
Business Support (18)
Central Administration
Jenny Bailey
Philip Priest
Nissar Mohammed
Ricky Allain
Isabel Lavis
HR
Marketing
Finance
Dr Adam Stoten
Rakesh Roshan
Dr Jon Carr
Dr Bharti Ranavaya
Dr Andy Robertson
Dr Andrew Bowen
Dr Carolyn Porter
Dr Alex Marshall
Dr Christine Whyte
Dr Ruth Barrett
Dr Richard Reschen
Dr Louis Pymar
Dr Richard Holliday
Chim Chu
Dr Fred Kemp
Dr Mark Gostock
Dr Weng Sie Wong
Carolyn Hall
Alex Allan
Viv Parry
Simon Gray
Renate Krelle
Dr Chandra Ramanujan
Dr Fiona Story
Barney Cullum
Evert Geurtsen
Team Leader Vacancy
Dr David Churchman
Dr Jamie Ferguson
Roy Azoulay
Dr Manjari Chandran-Ramesh
Janeen Wilson
Gemma Allnutt
Amanda Thornton
Legal
Operations
Dr Mairi Gibbs
Seed Investment
Dr Paul Ashley
Dr Angela Calvert
Andy Self
Dr Sarah Deakin
Dr Matthew Carpenter
Dr Nikolaos Chalkias
Dr Brijesh Roy
Medical Sciences
Dr Linda Maxwell
Patent & Licence
Steven Bayliss
Zuzana Weberova
Kate Spanchak
Andrea Alunni
Administration
Paresh Jasani
Kristin Hayes
Staff & Associates: 87
isis-innovation.com
MBAs: 14
PhDs: 40
Oxford University Consulting(7)
Andrew Goff
Project Managers
Susan Clark
Gurinder Punn
Dr Josef Walker
Kerry Antcliffe
Administrators
Magda Bezdekova
Selina Woodcock
Isis Enterprise (24)
Consultants
Dr David Baghurst (Hong Kong)
Ya-hsin Shen (Hong Kong)
Dr Jimmy Wang (Hong Kong)
Dr Wenming Ji
Renchen Liu
Kenji Aiba (AC-Japan)
Xiaowei Hu (AC-China)
Dr Costas Chryssou
Dr Sarah Bond
Dr Andrew Barber
Dr Mireya McKee
Dr Steve Cleverley
Elena Andonova
Dr Alexandra Bush
Dr Sarah Macnaughton
Gaurav Misra
Bruno Reynolds
Eva Baltar, Manuel Fuertes (AC-Spain)
Dr Tim Hart (AC-UK)
Dr Chris Moody
Dr Salvador Venegas (AC-Mexico)
Operations
Shelagh Harrison, Chloë Cairns
IsisActing
Innovation
as Multi-dimensional
Staff
Intermediaries
Investor axis
£ -> £££
3D – Spin-out
Academic axis
£ -> Research
2D – Licence, Consulting
Commercial axis
Research -> £
isis-innovation.com
Intermediaries - International
Intermediaries – 4th Dimension
isis-innovation.com
Intermediaries – 4th Dimension
isis-innovation.com
Isis Impacts
• The impact of Isis activities
is seen through the takeup of new technologies and
ideas that form the basis
for new products and
services.
isis-innovation.com
Publications
Isis on Twitter
Isis E-News & IAN E-News
LinkedIn
Chinese Isis E-News
Facebook
isis-innovation.com
@isisinnovation
Oxford University Technology Spin-outs (post 2000)
Third Phase, Mindweavers, Oxford BioSignals, Oxford BioSensors, TolerRx,
OXIVA, Pharma DM
OxLoc, Oxford Bee Co, Oxford Ancestors, Novarc, Oxford ArchDigital, Natural
Motion, Inhibox
Pharminox, Minervation, Oxford Biomaterials(Spinox), Zyentia, Oxitec, Oxford
Immunotec, Oxford Risk, GlycoForm, BioAnalab
2000
7
2001
7
2002
9
2003
4
Summit(Vastox)*, ReOx, Riotech, OCSI
2004
4
Avacta(OMD)*, G-Nostics, Surface Therapeutics, EKB Technology
2005
5
2006
7
2007
4
Eykona Technologies, Clinox, Oxford Biodynamics, Crysalin
2008
4
Semmle, Oxford-Emergent TB Consortium, Navetas(ISE), Organox
2009
3
Oxford Financial Computing, Zyoxel, Oxford Yasa Motors
2010
4
OxEms, Kepler Energy, IXO, Oxford PhotoVoltaic
2011
5
Oxyntix, Oxtex, Oxford Multi Spectral, Oxford Imaging Detectors, OCB
2012
4
Intelligent Ultrasound, OxEHealth, Oxford Vacmedix, Run3D
2013
Oxford Nanopore Technologies, Oxford RF Sensors, Oxbridge Pulsars, Celleron,
Oxford Catalysts*
TDeltaS, Oxford Medistress, Particle Therapeutic, Aurox, Oxford Advanced
Surfaces*, Cytox, OxTox
[1] Perspectum Diagnostics
* Stock exchange listing
Total external investment to date in 68 spin-outs since 2000: £506m
£46m 1st round Seed/Business Angels – £460m follow-on Investment Capital
isis-innovation.com
TT
Spin-outs – The Players
TT
Founder
Researchers
Shareholder, Director,
Consultant
N
V
Investor (1)
Investor (2) ?
E
Isis - licence,
University shareholding,
director (OSEM)
Shareholder,
Director
Shareholders
I
Isis Technology
Transfer Manager
S
Manager (1)
Manager (2)?
T
CEO, Shareholder
M
Lawyers
Bankers
Time
isis-innovation.com
N
Lawyers
Accountants
T
Bankers
Advisers
Accountants
E
Investment Sources
Oxford University Challenge Seed Fund
• Launched with £4m in 1999
• University provided £1m; HM Treasury, Wellcome, Gatsby £3m
• £5.7m invested in 102 projects – development, seed equity
• Resulting in Equity stakes in 31 spin-outs, 4 completed licensing
deals & 33 active technology projects. These 31 spin-outs have
attracted £80m seed/venture investment
Oxford Invention Fund
• Donations to the University of Oxford as part of Oxford Thinking,
the University’s overall fund raising Campaign
• Invest in development of new technologies and innovation from
Oxford
Isis Angels Network
• Business Angels, Seed/Venture Capital
• 100 members
• Events, No Charges
isis-innovation.com
Isis Software Incubator, established in 2010
• Support for early-stage software
ventures from Oxford University
• Assists the creation and
development of a software business
opportunity, whether or not a
company has yet been incorporated
• Isis provides commercial mentoring,
negotiation support, services, desk
space, access to business networks
• Projects that have a credible
business concept and need:
• Substantial work to develop IP and
build a realistic commercial prospect
• With entrepreneurial founders
• But do not need patents, investors,
full-time management
isis-innovation.com
Investment Gap
isis-innovation.com
Piers & Bridges
Business is over here !
isis-innovation.com
Building Bridges
isis-innovation.com
Vision for Isis
• Technology
• From Oxford and elsewhere
• Innovation
• Successful exploitation of new ideas
• For People
• Health & Wealth of Society
isis-innovation.com
Conclusions – How Isis Works
• Universities
• Technology Transfer is a good thing
•
Part of University purpose; may make money for University and researchers
• It does not happen on its own
•
You need to invest resources in People, Patent budget, Proof-of-Concept
• You need a policy framework
•
Who owns the inventions; who shares the rewards
• It takes a long time … So start and do not stop.
• Business
• Access to technologies, resources and expertise
• Help understand universities
• Help your business innovate
• Investors
• Source of investment opportunities
• Home for entrepreneurs
• Government
• Stimulates innovation and enterprise
• Improves society
isis-innovation.com
Elements
isis-innovation.com
Elements
Research
Base
Business
Industry
Finance
Commerce
Universities
Research Institutes
Research Hospitals
Government
Tax
Grants
isis-innovation.com
Elements – Research Base
• Supportive Vice-Chancellor, Rector, Provost, Director
• & Senior Researchers
• Research Activity
• High volume & quality
• Researcher engagement
• Leadership
• Stories
• Resources
• University Policies
• IP Ownership / Revenue sharing / Spin-outs
• Disputes
• Research Services Office
• Manage relationship with Research funders
• Access to Proof of Concept / Seed funds
• To accelerate technology transfer
• Technology Transfer Office
• Adequately resourced
isis-innovation.com
•
•
•
•
Policy
Patent Budget
People
Proof of Concept
Nothing beats a good story
isis-innovation.com
Publications
Isis on Twitter
Isis E-News & IAN E-News
LinkedIn
Chinese Isis E-News
Facebook
isis-innovation.com
@isisinnovation
Elements – Business & Finance
• Business Networks
• Innovative Technology companies
• As Licensees
• Business Angels
• Seed & Venture Capital
• Entrepreneurs
• Professional Advisers
• Banks / Accountants / Lawyers / Property
isis-innovation.com
Innovation Funnel
Professor Henry Chesbrough
Open Innovation: The New Imperative for Creating and
Profiting from Technology (HBS Press, 2003).
isis-innovation.com
Oxford incubators & science parks
Begbroke
Science Park
Isis Software
Incubator
Oxford
Entrepreneurs
Incubator
Oxford Centre
for Innovation
Oxford Magnet
Oxford Low
Carbon Hub
Oxford
BioEscalator
Harwell - European
Space Agency's Business
Incubation Centre
Oxford Hub
Science Vale
Enterprise Zone
Oxford
Science Park
Milton Park
isis-innovation.com
Source: Google Maps
Oxford Science Parks
isis-innovation.com
Oxford Entrepreneurs Incubation Centre
isis-innovation.com
Elements - Government
• Tax incentives
•
•
•
•
SME Benefits
CGT & Income Tax
Tax credits & Tax relief
‘Patent Box’
• Grant programmes
• Technology Transfer capacity, proof-of-concept
• Businesses
• Legislative framework
• Intellectual Property
• Company law
• Public procurement
• Support & Clarity & Consistency
isis-innovation.com
Elements – A fourth area ?
• Non Governmental Organisations
• Charities
• Foundations
• Not-for-Profits
• Social Enterprise
isis-innovation.com
Elements
Research
Base
Business
Industry
Finance
Commerce
Universities
Research Institutes
Research Hospitals
Government
Tax
Grants
isis-innovation.com
Elements
Research
Business
Base
Government
isis-innovation.com
The Innovation System
Start-ups
Journalists
‘City deal’
University
Researchers
Recruitment,
head-hunters
Technology
companies
Angel
Investors
Government
Labs
Bankers
Students
Lawyers
Science
Parks
Other
universities
Industry
Angel
Networks
Accountants
Local
Government
Commercial property
managers
Incubators
Investment
Funds
Research
Institutes
Business
isis-innovation.com
Business
networks
Public
Relations
Members of
Parliament
Hospitals
Local
Enterprise
Partnership
Technology Transfer
organisations
Consultants
[Isis] helps researchers - and students
- who wish to commercialise the results
of their research
isis-innovation.com
Themes …
• Impact
•
•
•
•
Change
Benefits
Academic view of relationships with industry
TT is smaller part of a bigger picture
• Specialisation
• Vanity subjects … ?
• Convergence
• Technology Transfer
• Entrepreneurship – Social & Business
• Distributed
• Young people
isis-innovation.com
www.isis-innovation.com
Isis Innovation Ltd, Ewert House, Ewert Place, Summertown, Oxford OX2 7SG
T 01865 280830
F 01865 280831
E innovation@isis.ox.ac.uk
Register to receive Isis E-News at: www.isis-innovation.com/news/enews
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