Dr Sudhir Shah MD DM Neurology Your Well Wisher... www.sudhirneuro.org 2nd June 2013 2 3 Purpose of life Everybody wants to live Everyone wants to be happy ( nobody wants unhappiness ) Everyone wants peace ( nobody wants otherwise ) Ultimate purpose of life is to enjoy and live happily and make others happy… 4 Disclaimer Nobody is perfect and all of us are students Easy to Preach, but not very difficult to Practice Happiness is not really hypothetical Definition of Happiness varies from person to person Also it is dynamic in the same person usually It is journey rather than destination But it is the dialogue we have to initiate now... 5 Plan of my talk Defining Happiness Psychology of Happiness Neuroscience of Happiness Measuring Happiness How to be Happy Philosophical and Spiritual perspective 6 Happiness Defined Aristotle put it, “Happiness is the meaning and purpose of life, the whole aim and the end of human existence”! 7 Happiness Redefined Happiness is: A pleasant feeling A positive evaluation or judgment A favorable explanation after the fact An optimistic expectation A sense of inner peace A sense of connectedness A spiritual experience 8 Psychology and Evolutionary History The Triune Brain 9 But to Cope with Urgent Needs, We Leave Home . . . Avoid: When we feel threatened or harmed Leads to Anxiety disorders; PTSD; panic, terror; rage; violence → leads to insecurity & pessimism Approach: When we can’t attain important goals Leads to Addiction; over-drinking, -eating, -gambling; compulsion; hoarding; driving for goals at great cost→ Frustration & disappointment Attach: When we feel isolated, disconnected, unseen, unappreciated, unloved Leads to Borderline, narcissistic, antisocial PD; symbiosis; folie a deux; “looking for love in all the wrong places” → Rejection, unloved This is the brain in its reactive mode of functioning - a kind of inner homelessness 10 Three Levels of Happiness Three levels of happiness : pleasure, joy and bliss All people fall into one of three groups... those who are spiritually awake, those who are asleep and those who are somewhere in the middle. Your own personal definition of happiness will depend on which of these groups you belong to 11 Pleasure For those who are largely asleep Happiness is sought from outer world and is characterized by pleasure Sensual, instinctual and physiological Always perpetual and demand for more and more. Leads to inevitable pain ANIMAL INSTINCT 12 Where they find pleasure Food Sex Places Listening Music Fragrance 13 What does it do for you? 14 fMRI during visual imagery 15 16 Physical Pleasure and the Ventral Striatum When people experience physical pleasure, the ventral striatum is activated (George, 1995) 17 Chemicals of Pleasure 18 NORMAL SEROTONIN CATECHOLAMINE DOPAMINE DEFICIENT you’re positive, confident, flexible, and easy going Become negative, obsessive, worried irritable, and sleepless you’re energized, upbeat, and alert you can sink into a flat, lethargic mood You’re more talkative and excitable. It affects brain processes ability to experience pleasure and pain Have depression, chronic boredom, loss of satisfaction, chronic fatigue, mood swings and poor attention 19 Joy Begin to feel happy for no particular reason Comes from inner world (self) More psychological Refined Desires Through service to mankind, success, achievements & spiritual practices like prayer, chanting , religious reading and satsang JOY is HUMAN 20 Achievement 21 Engagement 22 Meaning 23 Spiritual practices 24 Abstract perception of joy 25 Neural circuitry of Joy 26 Chemicals of Joy NORMAL OXYTOCIN VASOPRESSIN Good social recognition, calm and relaxed mood, ego faculty Good social Recognition, Prompt responsive , attentive for stressful situations DEFICIENCY Become negative, depressed , socially withdrawn , anxious Socially withdrawn, feel overwhelmed in stressful situations 27 Bliss The highest state Here mind and all its activity ceases Our consciousness becomes identified with universal consciousness Experience of just being Permanent meditative state Fully awake PIOUS PERSONS 28 Inner Peace Inner Peace refers to a state of being “mentally” and “spiritually” at peace, with enough knowledge and understanding to keep oneself strong in the face of discord or stress. Peace of mind is generally associated happiness, bliss and contentment with 29 Mindfulness Practice Observing the body and mind intentionally Letting experiences unfold from moment to moment and accepting them as they are Observing thoughts without getting caught up in them. No effort to control anything except the focus and direction of the attention. Not a passive process, yet does not involve trying to get anywhere Eating meditation, sitting meditation, working meditation and meditation during each act is the goal of mindfulness practice 30 Meditation Patanjal Dhyana Anapan Sati Smriti Upasthan Vipashyana Preksha Dhyana Jain Dhyana Spand Dhyana Mantra Dhyana Nabhi Dhyana Swapna Dhyana Nidra Dhyana Yoga nidra, Nyas Kriya Yoga Mrutyu Dhyana T.S Meditation Kundalini Kayotsarga Tratak Suryasamyam Adarshdhyana (mirror) Swaminarayan Dhyana Arup Dhyana Purnayoga Dhyana Atit Dhyana (past) Bhavidhyana (future) Sarpalanchan Dhyana Samarpana Dhyana Tathata Hoo-Dhyana (Dynamic Meditation) Sahaj Dhyana Your own system All methods are great 31 Vipashyana Operation of the mind, by the mind Calm and quiet mind Awake and attentive mind Equanimous mind 32 symbolic representation of the self 33 Neural Circuits of Meditation 34 Endorphins 35 + Glutamate Arcuate Nucleus of Hypothalamus Prefrontal cortex Activation by Meditation + Endorphins + Experience of Well being 36 37 + Glutamate Reticular nucleus of Thalamus Prefrontal cortex Activation by Meditation + GABA + Experience of just being Inhibition of Superior 38 Parietal lobe The process of meditation apparently increases activation in the prefrontal cortex and stimulates the reticular nucleus of the thalamus, leading to release of inhibitory neurotransmitter GABA. GABA have a central role in cortical inhibition and Cortical Silent Period, modulating cortical excitability and neural plasticity 39 Blissful chemicals NORMAL ENDORPHINS GABA DEFICIENT you’re full of cozy feelings of comfort, pleasure, and euphoria. you may be crying during commercials and overly sensitive to hurt. you’re relaxed and stress-free. you’ll be wired, stressed, and overwhelmed 40 So, in conclusion Pleasure is dependent on others, joy less so and bliss is completely independent of anything Pleasure is animal, joy is human and bliss is next to Divine 41 Three levels of Happiness BLISS Happiness JOY Being part of something bigger than yourself GABA, Endorphins Happiness within Oxytocin, Vasopressin, Dopamine PLEASURE Worldly things Serotonin, Dopamine , Catachoalmines Time and knowledge 42 Instruments Used in the Study of the Brain and Happiness Can we really measure happiness, and how? Who would know better than Neurologists and psychologists? 43 Neuropsychological testing (three level questions ) How are you feeling right now (from 1 to 7)? 1) Introspection All things considered, how happy are you these days (from 1 to 7)? 2) Introspection, comparative judgement On the whole, how good do you think your life is (from 1 to 7)? 3) Introspection, comparative judgement, relative to conception of ‘the good life’ 44 Happiness ‘Continuum’ Level 1 - Momentary feelings - Mood - Pleasures - Not suffering Level 2 Level 3 - Judgements about feelings - Net level 1 happiness - Well-being - satisfaction - Holistic evaluation of value of life - Flourishing - Needn’t include pleasures More emotional, sensual, and reliable More cognitive, moral, and easily biased 45 Electroencephalogram (EEG) 46 Magnetic Resonance Imaging (MRI) Magnetic Resonance Imaging (MRI) uses changes in electrically charged molecules when they are place in a magnetic field to assess differences in cerebral activity in different regions of the brain 47 Functional Magnetic Resonance Imaging (fMRI) • Functional Magnetic Resonance Imaging (fMRI) tracks the brain’s blood flow and oxygen use two measures of neuron activity • fMRI is useful to find out emotional processing in particular areas of brain 48 Positron Emission Tomography (PET) Positron Emission Tomography (PET) scans are good for showing the many brain structures that may be involved in a functions like pleasure and help to examine the processing of neurotransmitters 49 The Brain and Happiness Different components of happiness are found in different areas of the brain. That is, happiness does not seem to have a clearly defined neurobiological home 50 Happiness and the Pre-frontal Cortex Laughter responses are generated in the prefrontal cortex. (George, 1995) Pleasant film clips, pleasant tastes, &cash incentives increase left pre-frontal cortex activity Unpleasant film clips, unpleasant tastes, and a threat of cash loss raise activity in the right pre-frontal cortex 51 Happiness, the Rostral Anterior Cingulate Cortex and the Amygdala When people think about good events the rostral anterior cingulate cortex (rACC) and the amygdala are activated. However, the correlation with optimism was biggest with the cingulate cortex (Phelps & Sharot, 2007) 52 Happiness and the Temporal and Parietal Lobes When people feel happy, the characteristic pattern shows a decrease of activity in the brain that are committed to forethought and planning—the temporal and parietal lobe (George, 1995) 53 Who is more Happy? Young, middle-aged, or old? Married or Single? Men or Women? Spirituality? Rich vs. Poor? 54 Geography of Happiness Green = Happiest > Blue > Purple > Orange > Red = Least Happy; Grey = Data not available 55 Percent 100 Age group 80 60 40 20 0 15- 24 25- 34 35- 44 45- 54 55- 64 65+ AGE-WISE: % “Satisfied” or “Very Satisfied” with Life as a Whole 56 Percent 100 Males 80 Females 60 40 20 0 Satisfied Very happy Pooled data from 169,776 interviews. Gender and Well-Being in Sixteen Nations 57 45 Percent Very Happy 40 35 Married 30 25 Never married Separated 20 Divorced 15 10 5 0 Men Women 58 Percent “very happy” 100 Spiritual commitment 80 60 40 20 0 Low High Spirituality and Happiness 59 45 41 40 35 29 30 25 23 20 15 10 5 0 Not Close/Not Believe Somewhat Close Extremely Close 65 % Very Happy and Felt Closeness to God (n = 9896, NORC, 1983-1991) 60 Money and happiness Money produces shortterm benefits; More money will not raise well-being 61 Does money buy Happiness? 62 63 Money and happiness Money can bring security as well as comfort & pleasure It can bring improved standard of living and education But Money corrupts , success corrupts They take away morality, relationships, health, bliss and peace 64 Understanding happiness Happiness is not something that happens, that money or power can command It is only by controlling our inner experience that we can become happy Happiness cannot be reached by consciously searching for it 65 Road to Success Money Fame Achievements Awards Possessions Road to Joy, Bliss and Peace Godhoodness Spirituality Philosophy Morality Religion 66 What do you remember? Applause dies away! Trophies gather dust! Winners are soon forgotten But you remember ,the ones who take care of you & appreciate you 67 “PHYSICIAN HEAL THYSELF” 68 Why Doctors are not happy Professional carrier Money , fame Teaching Time management Academics Traffic , mobile Research Staff management Administration Misunderstandings Family life Legal issues Children issues Paper work Interpersonal relationships Demanding patients Competition Caregivers stress Negative emotions like ego Physical and Mental jealousy HEALTH 69 Determinants of Happiness 70 Gene therapy VMAT : Vesicular Mono Amine Transporter gene on chromosome 10q25 Produces the sensations of mystic experiences, including the presence of God and spirituality as a state of mind MAOA : Monoamine oxidase A on X chromosome Low-expression is associated with higher selfreported happiness in women 71 Determinants of Happiness 72 To control your circumstances 1. Reduce your commitments 2. Reduce your interactions with persons sanjog mula jiven pattaa dukha parmpara... The more you have contacts with persons and situations, the more will be your unhappiness ( cascade of problems ) Lord Mahavir 73 How to enjoy journey of life ? Key to Happiness Physical Moral Mental Religious Spiritual 74 Happiness And Peace : A Physical perspective pahelu sukh te jate narya Eat right Exercise Get enough sleep Good excretory functions (biju sukh?!) Learn to relax Laugh exhaustingly Love abundantly 75 GET ENOUGH SLEEP 76 Nix Coffee? 77 WALKING 78 RESISTANCE TRAINING 79 VENTING 80 Massage 81 YOGA 82 Laugh frequently Laugh frequently At yourself and not others Laugh from the core of your spirit not in artificial ways Learn to laugh out in all mistakes and bad situations 83 Smile! Smiling is the main way to tell if someone’s happy… but only if they are real smiles Smile solves many problems 84 Silence! Silence avoids so many problems 85 Love abundantly 86 The Rewards of Love 87 Helping Others 88 Dopamine Serotonin Oxytocin Endorphin Exercise, Food & Mood (Happy Chemicals) 89 Dopamine The omega-3 fatty acids are proven to create dopamine. Kauncha like seeds also. Useful sources of building blocks for dopamine: Apples Beet Cucumber Green leafy vegetables Honey Cheese Sweet peppers Watermelon 90 Serotonin To create serotonin eat low sugar carbohydrates such as fruits and vegetables Bananas are especially powerful serotonin inducers and bring on an immediate calming effect because of the complex B vitamins they have Try some light stretching or breathing exercises along with some soothing music to complete the mood. 91 Oxytocin Eating comfort foods: Eating your favorite food such as chocolate, ice-cream or any meal that you really enjoy will release oxytocin 92 How Chocolate Could Influence Brain and Behavior 93 Endorphin Complex carbs like pasta, breads, and foods with natural glucose, like grapes make the perfect mixture for creating endorphins Eating spicy food like hot chili pepper A routine of aerobic activity: brisk walking, biking, swimming or massage or 94 Medical management If happiness has a biological cause in the brain, then we will be able to influence it with drugs, surgery, bionics etc… but should we? If our brains show equal ‘happiness activity’, then are we equally happy? How can we know this? 95 Psychological counselling 96 Mood elevators 97 Future of Happiness 98 The God Gene 99 Building on Strengths Key to Engagement and Meaning Gratification and satisfaction 100 Six Virtues for Gratification From the great philosophies and religions of the world: wisdom and knowledge courage love and humanity justice temperance spirituality and transcendence 101 Six Areas of Strength Wisdom & Knowledge Temperance Courage, firmness Transcendence Love, warmth Leadership ,Justice 102 KNOWLEDGE & WISDOM 1. Creativity 2. Curiosity 3. Love of learning 4. Wisdom / perspective 5. Open-mindedness COURAGE & FIRMNESS 6. Bravery 7. Persistence 8. Integrity 9. Vitality HUMANITY & LOVE 10. Give & receive love 11. Kindness 12. Social intelligence LEADERSHIP & JUSTICE 13. Citizenship 14. Fairness 15. Leadership TEMPERANCE 16. Forgiveness / mercy 17. Modesty / humility 18. Prudence 19. Self-regulation TRANSCENDENCE / SPIRITUAL 20. Appreciation of excellence and beauty 21. Gratitude 22. Hope 23. Humor 24 Spirituality 103 3 “C’s” of Happiness Control Challenge Commitment 104 *Challenge* Openness To New Experiences Expanding Social Support Network 105 Self Awareness and Reflection *Commitment* 106 Self Discipline and Self *Control* 107 Happiness and friendship A person doesn’t need a large number of friends to be happy – he needs one the best friend 108 Learning from Children Spend time with children. Learn more about laughter, spontaneity, curiosity, acceptance, resilience, trust, determination, and your imagination They are here to teach us! 109 Happiness for children By giving them Your Time Education and knowledge Culture and attitude Wisdom and art 110 How to enjoy journey of life ? Key to Happiness Physical Moral Mental Religious Philosophical Spiritual 111 Happiness : religious, philosophical and spiritual key 112 Address of Happiness At some stage you realize happiness are not outside that peace and The root cause of miseries : thoughts, desires, emotions , ego, attitude , mind wondering between past & future, raga and dwesha ( anger, greed, deceit and passion) …etc all functions of mind 113 Thoughts... We are what we think All that we are arises with our thoughts With our thoughts we make the world Speak or act with an impure mind and trouble will follow you, as the wheel follows the ox that draws the cart Your worst enemy cannot harm you as much as your own thoughts, unguarded 114 Attitude Attitude is a little thing that makes a big difference 115 Attitude “ The Longer I live, the more I realize the impact of attitude on life. Attitude to me, is more important than facts. It is more important than the past, than education, successes, than what other people think or say or do. It is more important than appearance, giftedness or skill. It will make or break a company…….. a church…. a home. The remarkable thing is we have a choice every day regarding the attitude we will embrace for that day. We can not change our past..... we cannot change the fact that people will act in a certain way. We cannot change the inevitable. The only thing we can do is to play on the only string we have, and that is our attitude……. I am convinced that life is 10% what happens to me and 90% how I react to it. And so it is with you….. We are in charge of our Attitudes ”. - Charles Swindoll 116 Forgiveness REACH (Everett Worthington) Recall the hurt Empathize with the perpetrator Altruistic gift of forgiveness Certify you forgive Hold on to the forgiveness Use wisdom and discretion: Typically you do NOT tell the perpetrator that you have forgiven him/her GHALIB…..hum ne jindgi ko aasan kar diya….. 117 Interpersonal relationships 1. Altruism & Friendship ( Maitri) 2. Appreciation & Respect ( Pramod ) 3. Equanimity & Guidance ( Madhyastha ) 4. Forgiveness, Compassion & Prayers (Karunya ) 118 Acceptance “ God grant me the courage to change the things I can, the serenity to accept the things I cannot, and the wisdom to know the difference.” Cultivating an attitude of non-judgment Acceptance is not resignation It is a realization and appreciation of the inherent imperfections of life 119 Buddhism on Happiness There is no fire like desire. There is no weakness like anger. There is no suffering like the khandhas. There is no happiness greater than peace (Dhammapada, 202 & 208) 120 Mathematics of happiness Happiness = 2 x happiness 2 Happiness = Objects Desires Total units of Happiness remains same 121 Ambitions Where Ambitions end, Happiness begins Amount of balance in the bank at the time of your death is the extra work that you have done, which you should not have done 122 ichao rahi jaya Ane swas KhutiI jaya tene Mrutyu kahevay, ichao pauri thai jaya Ane swas rahi jaya tene Moksha kahevay. 123 Vaishnavajan Eyes : compassion and satisfaction and not reflecting greed or jealousy ( lobha ) Words : forgiveness , appreciation and care and not anger or criticism ( krodha) Mind : equanimous and fair and not having raga (attachment) or dwesha(disliking ) Emotions : calm and passionless and not having perversions or aspirations ( kama ) Nature : gentle , humble and reliable and not fraudulent or hippocrate ( maya ) Behaviour : Loveful and kind and not hatred or discard 124 Religion Opens Doors of Happiness Religion confers upon man eternal life and guides his footsteps in the world of morality It opens the doors of unending happiness and bestows everlasting honor upon the human kingdom It has been the basis of all civilization and progress in the history of mankind 125 Ethics 126 Spiritual reading Philosophy of Karma 127 Satsang 128 Chanting 129 Prayer : four steps... 130 Comparison of Baseline to Prayer : Limbic inhibition Baseline Scan LIMBIC Prayer Scan LIMBIC 131 Ratnatrayi Righteous knowledge Righteous perspective Righteous conduct Lead to eternal happiness 132 PATANJAL RAJ YOGA Yama : Nonviolence, truth, non-stealing celibacy and aparigriha (Non-collectiveness) Niyama : Purity, Penance (Austerity) Satisfaction Spiritual learning Worship & dedication Asana : Pranayama : Pratyaahar : Dharna : Dhyana : Samadhi : 133 T.S.MEDITATION 134 SPECT Images at Baseline and During Meditation Prefrontal Cortex Baseline Prefrontal Cortex Meditation 135 SPECT Images at Baseline and During Meditation Baseline Meditation Superior Parietal Lobe Superior Parietal Lobe 136 Christian Nuns, Recalling Profound Spiritual Experiences Beauregard, et al., Neuroscience Letters, 9/25/06 137 Lazar, et al. 2005. Meditation experience is associated with increased cortical thickness. Neuroreport, 16, 1893-1897. 138 Set Peace of mind and Happiness, your highest goal and organize your life around it Ask yourself before each thought, action and speech… whether this will bring happiness and peace 139 12 Secrets of Happiness Accept What You Have : NOBODY GETS MORE OR BEFORE Enjoy What You Do and without expectations Live For Today and in this present moment Choose Happiness Improve Relationships… Always appreciate, never criticize Don't Compare, but Be Yourself Preserve health and monitor it Stop Worrying : THIS WILL ALSO GO AWAY Get Organized and financial management Think Positive Moral values : DO ONLY THOSE THINGS TO OTHERS, WHICH… Spiritual practices 140 Address of Happiness 1, Spiritual mansion , Meditation hall , Self realization lane, Philosophy society, Charity chowk, Morality area , PIN : 000000 Religion station 141 Happiness is inside you 142 So Remember... 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