Johannes Charlier, DISCONTOOLS Project Manager 4th September, 2014 DISCONTOOLS- a method to prioritize animal health research in the E.U. 1 Summary • DISCONTOOLS – Origin – Questions tackled – The database – Global hub for disease prioritisation in terms of research needs – Work Programme • Conclusions 2 ETPGAH – Vision to Action Plan August 2005 Stakeholders, led by industry, come together to agree on a common vision for the technology May 2006 Stakeholders, define a Strategic Research Agenda setting the necessary mid- to longterm objectives July 2007 Stakeholders, implement the Strategic Research Agenda with the mobilisation of significant human and financial resources Framework Programme 7 Coordination of Funding April 2008 - 45 months €997,218 Feb 2011 - 48 months €999,130 Jan 2012 - 48 months €2m 4 Background • DISCONTOOLS was a Stakeholder driven project – All European & Global Stakeholders welcomed to join • 5 Year Project - March, 2008 to February, 2013 • Output – – – – Disease database – 52 diseases Gap analysis for each disease Prioritisation model on public website Methodology to identify & deploy new research technologies in the animal health research world 5 Questions Tackled • How do we decide where to spend scarce research resources? • Which diseases? • Which gap(s) in each disease? • Priority of whom? – Research community? – Funders of research? – People at coal face – CVO, Vet, Farmer? – Industry? 6 www.discontools.eu 7 The disease database 8 View disease info – control tools 9 Disease scoring criteria 10 Gap analysis – Diagnostics, vaccines, pharmaceuticals 11 Sample report – all diseases ranked by score 12 Prioritisation of Epizootic diseases 13 Prioritisation of Zoonotic diseases 14 Prioritisation of Food producing diseases 15 16 17 18 19 Achievements & Economics • • • • • • • DISCONTOOLS finished on February 28th, 2013 Built consensus across stakeholders Focus on critical gaps Agreement on need to continue Make best use of €400m from public sector & €400m from private sector Hasten the arrival of new diagnostics, vaccines & pharmaceuticals Disease burden of 20% on animal production valued at €141b (in EU) – reduce cost by €28b!20 Continuing DISCONTOOLS Work! • • • • • Business case made – need € 100,000 per year Need 14 countries to fund at € 7000 each 10 countries/funders have committed to date others considering Held meeting of funders in February, 2014 Sufficient funds to re-launch DISCONTOOLS! 21 DISCONTOOLS Work in 2014 • Commenced DISCONTOOLS work in June, 2014 – Update existing diseases over time – Add new diseases – Refine & further develop model 22 12 diseases in focus - 2014 • • • Existing - AI, ASF, BT, Campylobacter, Cysticercosis, E. coli, FMD, Nematodes, ParaTB, PRRS, SIV New – PEDV List determined by funders with offer to work on Cysticercosis & PEDV 23 Logistics • Expert Groups formed or being formed ideally including: – laboratory expertise, an epidemiologist, an industry representative, a diagnostics expert and an individual with economic/trade expertise • Documents to be updated: – Disease & Product analysis – Gap Analysis – Prioritisation 24 – 2 page summary Conclusions - 1 • • • Public website with searchable database Stakeholder agreed prioritised research gaps Research agenda for the future has been established! • Focus funding on prioritised research gaps – ANIHWA, Horizon 2020, Countries, Industry, Trusts, Foundations, Charities, etc. 25 Conclusions - 2 • • • • The work of DISCONTOOLS will continue & evolve driven especially by funders to meet their needs We should organise the deployment of € 800 million (3 billion globally) in the best way possible! The prize of hastening the development of new or better disease control tools is enormous - €28 billion per year in the EU alone! We should make DISCONTOOLS our global hub where we pool our resources 26 Rue Defacqz, 1 1000 Brussels, Belgium Tel.: +32 (0)2 543 7570 Fax: +32 (0)2 537 0049 For more information please consult: www.discontools.eu 27