DISCONTOOLS presentation at CYSTINET conference

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Johannes Charlier, DISCONTOOLS Project
Manager
4th September, 2014
DISCONTOOLS- a method to
prioritize animal health research
in the E.U.
1
Summary
•
DISCONTOOLS
– Origin
– Questions tackled
– The database
– Global hub for disease prioritisation in terms of
research needs
– Work Programme
• Conclusions
2
ETPGAH – Vision to Action Plan
August 2005
Stakeholders,
led by industry,
come together
to agree on
a common
vision for the
technology
May 2006
Stakeholders,
define a
Strategic Research
Agenda setting
the necessary
mid- to longterm
objectives
July 2007
Stakeholders,
implement the
Strategic Research
Agenda with the
mobilisation of
significant human
and financial
resources
Framework Programme 7
Coordination of Funding
April 2008 - 45 months €997,218
Feb 2011 - 48 months €999,130
Jan 2012 - 48 months €2m
4
Background
•
DISCONTOOLS was a Stakeholder driven project
– All European & Global Stakeholders welcomed
to join
• 5 Year Project - March, 2008 to February, 2013
• Output
–
–
–
–
Disease database – 52 diseases
Gap analysis for each disease
Prioritisation model on public website
Methodology to identify & deploy new research
technologies in the animal health research world
5
Questions Tackled
•
How do we decide where to spend scarce
research resources?
• Which diseases?
• Which gap(s) in each disease?
• Priority of whom?
– Research community?
– Funders of research?
– People at coal face – CVO, Vet, Farmer?
– Industry?
6
www.discontools.eu
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The disease database
8
View disease info – control tools
9
Disease scoring criteria
10
Gap analysis – Diagnostics, vaccines,
pharmaceuticals
11
Sample report – all diseases ranked by score
12
Prioritisation of Epizootic diseases
13
Prioritisation of Zoonotic diseases
14
Prioritisation of Food producing diseases
15
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17
18
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Achievements & Economics
•
•
•
•
•
•
•
DISCONTOOLS finished on February 28th, 2013
Built consensus across stakeholders
Focus on critical gaps
Agreement on need to continue
Make best use of €400m from public sector &
€400m from private sector
Hasten the arrival of new diagnostics, vaccines &
pharmaceuticals
Disease burden of 20% on animal production
valued at €141b (in EU) – reduce cost by €28b!20
Continuing DISCONTOOLS Work!
•
•
•
•
•
Business case made – need € 100,000 per year
Need 14 countries to fund at € 7000 each
10 countries/funders have committed to date others considering
Held meeting of funders in February, 2014
Sufficient funds to re-launch DISCONTOOLS!
21
DISCONTOOLS Work in 2014
•
Commenced DISCONTOOLS work in June, 2014
– Update existing diseases over time
– Add new diseases
– Refine & further develop model
22
12 diseases in focus - 2014
•
•
•
Existing - AI, ASF, BT, Campylobacter,
Cysticercosis, E. coli, FMD, Nematodes, ParaTB,
PRRS, SIV
New – PEDV
List determined by funders with offer to work on
Cysticercosis & PEDV
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Logistics
•
Expert Groups formed or being formed ideally
including:
– laboratory expertise, an epidemiologist, an
industry representative, a diagnostics expert and
an individual with economic/trade expertise
• Documents to be updated:
– Disease & Product analysis
– Gap Analysis
– Prioritisation
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– 2 page summary
Conclusions - 1
•
•
•
Public website with searchable database
Stakeholder agreed prioritised research gaps
Research agenda for the future has been
established!
• Focus funding on prioritised research gaps
– ANIHWA, Horizon 2020, Countries, Industry,
Trusts, Foundations, Charities, etc.
25
Conclusions - 2
•
•
•
•
The work of DISCONTOOLS will continue & evolve
driven especially by funders to meet their needs
We should organise the deployment of € 800
million (3 billion globally) in the best way possible!
The prize of hastening the development of new or
better disease control tools is enormous - €28
billion per year in the EU alone!
We should make DISCONTOOLS our global hub
where we pool our resources
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Rue Defacqz, 1
1000 Brussels, Belgium
Tel.: +32 (0)2 543 7570
Fax: +32 (0)2 537 0049
For more information please consult:
www.discontools.eu
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