Update on PED Research
Lisa Becton, DVM, MS, DACVPM
Dir. Swine Health Information & Research
National Pork Board
Current Status of PED
• PED continues to be a major health challenge for U.S.
producers into 2014
• Since it was first diagnosed in May of 2013, there have been a
total of 2962 cases reported:
– CASE reports are different than SITE reports.
– IA = 1095; OK = 290; NC = 367; MN = 396; KS = 171
– Data can be found at www.aasv.org
PED case #’s/month (as of Jan 31st , 2013)
States
OH, IN, IA
CO, MN, PA, OK, MO, SD, IL, MI
KS, NY, NC
TN, TX
WI
KY, MD
PED Cases 2013-2014
1000
NE, CA, WY
SC
900
800
# of Positive Cases
Case #'s
Apr-13 12
May-13 103
Jun-13 197
Jul-13 122
Aug-13 119
Sep-13 173
Oct-13 252
Nov-13 394
Dec-13 712
Jan-14 887
700
600
500
400
300
200
100
0
Apr-13 May-13 Jun-13 Jul-13 Aug-13 Sep-13 Oct-13 Nov-13 Dec-13 Jan-14
National Pork Board Focus
• Research focus - New virus therefore needed
research on PEDv and impact for US producers
• Development and communication of producer
information/resources
• Containment/management strategies
– Work with USDA/stakeholders and develop next steps
for emerging disease response
– Other needs?
PED Research Efforts
Development of Research Priorities
• *Swine Health Committee – producers,
veterinarians, advisors (university, government,
industry)
• PED Strategic Task Force
• Input from AASV and NPPC membership
• State Pork Association input
PEDv Research Priorities
Initial Research Priorities:
 Basic understanding of the characteristics and pathogenesis of PEDv and
development of standard samples for use
 Development and validation of diagnostic testing for antigen and antibody
detection for PEDv and for oral fluids
 Environmental stability of the virus on various surfaces and substrates and
effectiveness of sanitation efforts
 Epidemiology of the disease
7
Funded PEDv Research – June 2013
•
Hesse, KSU: 13-228 Tissue localization, shedding, virus carriage, antibody
response and aerosol transmission of Porcine Epidemic Diarrhea virus (PEDV)
following inoculation of feeder pigs
•
Wang, OSU: 13-222 Propagation of PEDV in tissue culture and development of
standardized reference samples for use in diagnostic testing
•
Collins, UMN: 13-238 Development and validation of isolation and diagnostic
testing detection for PEDv
•
Collins, UMN: 13-239 Development and validation of diagnostic testing for
antigen and antibody detection for PEDV
•
Yoon, ISU: 13-226 Oral fluid testing for cost-effective and efficient surveillance and
control of porcine epidemic diarrhea virus in swine populations
•
Funded PEDv Research (continued)
•
Morrison, UMN: 13-216 Epidemiologic investigation on propensity for lateral
spread of PED virus
•
Goyal, UMN: 13-215 Environmental Stability of PEDV (Porcine Epidemic Diarrhea
virus)
•
Holtkamp, ISU: 13-227 Evaluation of time and temperature sufficient to kill PEDV
in swine feces on metal surfaces
•
Holtkamp, ISU: 13-248 Evaluation of the efficacy of Stalosan®F for inactivating
porcine epidemic diarrhea virus (PEDv) and PRRS in swine feces on the surface of
trailers used to haul live pigs
PEDv Research for Fall 2013
• RFP was posted at www.pork.org/Research
• Proposals submitted to NPB
• Sow immunity proposals selected by the Committee
• Remaining proposals that meet the call priorities will
be reviewed Feb 19-20th, 2014
Funded Research for Sow Immunity - 2013
• Giménez-Lirola, ISU: 13-264 Defining PEDV maternal humoral
immunity and correlates of neonatal protection
• Clement, SDSU: 13-263 Duration and level of PEDV
neutralizing antibodies for clinical protection using feedback
protocols
• Murtaugh, UMN: 13-262 PEDV feedback protocol
optimization to improve immunity and productivity
Since June 2013, the Board has approved >$1,000,000 for PED
Additional PED project funded 2013-2014
• Pillatzki, ISU: 13-266 Feed transmission of PEDV to neonatal
pigs
• Bowman, OSU: 14-150 Bioassay for Porcine Epidemic
Diarrhea Virus contaminated feed
Since June 2013, the Board has approved >$1,000,000 for PED
Funding for 2014 - TBD
PEDv Research Focus for 2014
• Committee discussion Feb 19-20th on continuing
needs for PED research, to include:
– Further investigation of feed stuffs as vehicle for
infection
– Development of a rapid/pen-side test for feed
– Assess capabilities for whole genome sequencing from
current sample types
– Cooperation, communication and collaboration are
key to address this ongoing issue!
PED Research
• Information and
updates on funded
projects available at
www.pork.org/PED
Thank you!
lbecton@pork.org
515-223-2791
This message funded by America’s Pork Checkoff Program.