Neuroanatomy Basics Arcot Chandrasekhar, M.D. Ashok Kumar, M.D. November 5, 2013 MRI Titbits • MRI can provide axial, sagittal and coronal views. • MRI is best for tissue discrimination and is superior to CT. • Look at pre-contrast and post-contrast MRI as a pair. • T2 wtd MRI: There are many MRI sequences used to visualize specific tissues. • Flair and diffusion wtd images are a few examples. • The best way to distinguish T1 wtd MRI from T2 wtd MRI is by the appearance of CSF. CSF is bright in T2 wtd MRI and CSF is dark in T1 wtd MRI. Post-contrast sagittal T1 wtd MRI Post-contrast sagittal T1 wtd MRI Post-contrast sagittal T1 wtd MRI • For axial images you need to know the level. • The next set of images are axial sections of brain from top to bottom. Pre-contrast axial T1 wtd MRI Pre-contrast axial T1 wtd MRI Pre-contrast axial T1 wtd MRI Pre-contrast axial T1 wtd MRI Pre-contrast axial T1 wtd MRI Spinal cord anatomy Pre-contrast sagittal T1 wtd MRI of cervical spine Pre-contrast axial T2 wtd MRI of cervical spine at C5-C6 level Pre-contrast axial T1 wtd MRI of thoracic spine Pre-contrast sagittal T1 wtd MRI of cervical spine Pre-contrast sagittal T1 wtd MRI lumbar spine CSF dark in T1 wtd image Sagittal T2 wtd MRI of lumbar spine CSF bright in T2 wtd image CT Titbits • CT provides axial views of the brain and spine. • Computer reconstructed process can provide sagittal view. • Pre-contrast CT is best for evaluation of bone and acute hemorrhage. • Bone and acute blood appear hyperdense. • Post-contrast CT enables visualization of vasculature and abnormal brain tissue. • Normal brain does not enhance with contrast. • CSF is hypodense and dark. • Vertebra are counted down from C2 or up from S1. 6 Pre Contrast CT Brain Normal CT anatomy of cervical spine at the level of C1 vertebral body