B9902022 B9902037 周書民 胡紀豪 Broca's area Pierre Paul Broca reported impairments in two patients who had lost the ability to speak after injury of the brain. Since then, the approximate region he identified has become known as Broca’s area Wernicke ‘s area Karl Wernicke, a German neurologist and psychiatrist who discovered that damage to this area could cause a type of aphasia (now called Wernicke's aphasia or receptive aphasia) in 1870’s. Location Both in dominant cerebral hemisphere (97% in left hemisphere) Broca‘s area : posterior to inferior frontal gyrus Wernicke ‘s area : The posterior section of the superior temporal gyrus (STG) Location 唸看到的字詞 唸聽到的字詞 Wernicke ‘s aphasia impairment of language comprehension, and speech that has a natural-sounding rhythm but a jumbled syntax without recognisable meaning (sounds fluent but makes no sense) Broca‘s aphasia Patients with Broca‘s aphasia understand what is being said to them, but are unable to speak fluently. Other symptoms include problems with articulation, word-finding, word repetition, and producing and comprehending complex grammatical sentences, both orally and in writing. 比較 布洛卡區損傷(布洛卡失 語症) 使一個人無法講話 可以了解語言內容 無法用字詞 說話緩慢並且不連貫 韋尼克氏區損傷(韋尼克 氏失語症) 無法了解語言內容 可以清楚的說話但是字 詞的使用是無意義的組 合這種現象被稱為「字 詞沙拉」,因為他們把 字彙就像生菜沙拉混合 在一起使用 研究方法的演進與歷史 50年代初期Wilder Penfield 和 Herbert Jasper 用電刺激腦部 → 抑制語言 60年代 Wada測試,使用sodium amytal (amobarbital) 麻醉劑注入左右頸動脈 → 測試語言能力 近期使用腦部顯影技術(正子掃描) → 右腦損傷會有情緒上的問題,稱為aprosodia 補充 Right homologous area of Wernicke's area Research suggests that the area corresponding to the Wernicke’s area in the non-dominant cerebral hemisphere has a role in processing and resolution of subordinate meanings of ambiguous words. In contrast, the Wernicke's area in the dominant hemisphere processes dominant word meanings.