ANIMAL TISSUES Outline: CAVITE STATE UNIVERSITY Don Severino de las Alas Campus Indang, Cavite College of Arts and Sciences DEPARTMENT OF BIOLOGICAL SCIENCES ANIMAL TISSUES Epithelial tissues Connective tissues Muscle tissues Nervous tissues PREPARED BY: DMBICUA TISSUES HISTOLOGY Study of Tissues Epithelial tissue PREPARED BY: DMBICUA DEFINITION Tissues- group of similar cells specialized for the performance of a common function. Individual cells differentiate during development to perform special functions as aggregates There are 4 major types of animal tissues. STEM CELLS- undifferentiated cells. Connective tissue Muscle tissue Nervous tissue PREPARED BY: DMBICUA Epithelial tissue/ Epithelium Covering tissue for protection. Epithelial tissue/ Epithelium FUNCTIONS Protection- protects the underlying tissues from- mechanical injury, drying up, from harmful chemical and infection. Absorption- Epithelial lining of the intestine absorbs digested food. Excretion- Epithelial lining of the uriniferous tubules in the kidney helps in excretion of substances. Conduction- ciliated epithelium helps in conduction of substances. Secretion- Lining of the glands secretes substances. Exoskeleton- Nails, hairs, claws, feathers etc. are formed form the epithelial cells. Respiration- Lining of the lung brings about exchange of gases. Sensory function- epithelium of sense organs receive stimuli and convey nerve impulses. PREPARED BY: DMBICUA METABOLISM OF LIPIDS TYPES OF EPITHELIAL TISSUE Simply combine the two manner of classifying the epithelial tissue. First, determine if it has layers then determine the shape of the cells that makes up the epithelial tissue. Simply combine the two terms. Acc. To strata: Simple Acc. To shape: Squamous “simple squamous” Acc. To strata: Stratified Acc. To shape: Squamous “Stratified squamous” PREPARED BY: DMBICUA Simple squamous Simple columnar Simple cuboidal Stratified cuboidal Stratified squamous Stratified columnar Consist of renewable sheets of cells that have specific specializations. Basement membrane- separates epithelial tissues from underlying adjacent tissues. Epithelial tissues are classified in two ways, according to shape and according to strata (layers). Scale-shaped cells Box/cube-shaped cells Simple- when the tissue is single-layered. PREPARED BY: DMBICUA Column-shaped cells Stratified- when the tissue has many layers. Simple squamous epithelium Stratified squamous epithelium • Single layer of tightly packed, flattened cells • • Location: air sacs of the lungs, kidney glomeruli, lining of the heart and lymphatic vessels • Location: lining of esophagus, mouth and vagina. Keratinized variety lines the skin • Function: Allows passage of materials by diffusion and filtration • Function: protects underlying tissues in areas subject the abrasion Consist of many layers of cells Simple cuboidal epithelium • Stratified cuboidal epithelium Consist of single layer of tightly-packed cube cells • Location: kidney tubules, ducts and small glands, and surface of ovary • Function: Secretion and absorption Simple Columnar Epithelium Light micrograph (LM) showing simple columnar epithelium in the gall bladder. • Location: lining of digestive tract, and excretory ducts of some glands. Some columnar cells are specialized for sensory reception such as in the nose, ears and the taste buds of the tongue. • Function: Absorption and enzyme secretion Trachea epithelium. Light micrograph (LM) of a vertical section through the pseudostratified columnar epithelium from the trachea Pseudostratified Ciliated Columnar Epithelium Location: Lines bronchi, uterine tubes, and some regions of the uterus. Function: propel mucus or reproductive cells by ciliary action Transitional Epithelium • • • • These cells show great amount of flexibility. without distention (relaxed), the cells appear cuboidal-shaped when distended (tense), the cells appear squamous-shaped impermeable to salts and water • • found in urinary bladder, ureter, and pelvis of kidney urine/fluid builds up in these cavities, the transitional layers extend to relieve the stress PREPARED BY: DMBICUA Connective Tissue Binding and Supporting CONNECTIVE TISSUES Tissues that “connects” the whole body. The binding and supporting tissues that bind and support the body's other tissues and organs are known as connective tissues. • • • • • Most abundant tissue in the body They are the most diverse type of tissues in the animal body. It contains sparsely packed cells scattered throughout an extracellular matrix. The matrix consists of fibers in a liquid, jellylike, or solid foundation. The nature of the extracellular material determines the functional properties of the various connective tissues. TYPES OF CONNECTIVE TISSUE FIBERS • Collagenous fibers provide strength and flexibility. • Elastic fibers stretch and snap back to their original length. • Reticular fibers join connective tissue to adjacent tissues. 1. LOOSE CONNECTIVE TISSUE also called areolar connective tissue, contains numerous fibroblasts that produce collagenous and elastic fibers that wraps and cushions organs. 2. FIBROUS CONNECTIVE TISSUE Contains large amounts of collagen fibers and few cells or matrix material. • Irregularly-arranged fibrous connective tissues are found in areas of the body where stress occurs from all directions, such as the dermis of the skin. • Regular fibrous connective tissue is found in tendons and ligaments. 2. FIBROUS CONNECTIVE TISSUE 3. ADIPOSE TISSUE Consist of adipocytes which contain large fat droplets that push the nuclei close to the plasma membrane. Accumulation of these cells forms fat; type of a loose connective tissue. FUNCTION • Provides padding. • Acts as an insulator to slow heat loss. • Serves as a packing or filler material around structures of the body. • Provides reserve fuel 3. ADIPOSE TISSUE Consist of adipocytes which contain large fat droplets that push the nuclei close to the plasma membrane. Accumulation of these cells forms fat; type of a loose connective tissue. LOCATION: • Located under the skin (flanks, buttocks, breasts) • Fills bony sockets behind the eyes. • Surrounds kidneys (adipose capsule) • Located around heart and abdominal organs. Hepatic angiomyolipoma (benign liver tumor) showing epithelioid smooth muscle cells admixed with adipocytes. 3. ADIPOSE TISSUE Brown adipocytes chief cells of the brown adipose tissue Beige adipocytes - recently discovered type, found dispersed within white fat tissue; sometimes generate heat. White adipocytes main cells of the white adipose tissue 3. ADIPOSE TISSUE • White adipose tissue • Most common type, provides insulation, serves as an energy store for times of starvation or great exertion • Forms pads between organs • Subjected to lipolysis- breaking down of triacylglycerol into energyrich fatty acids and glycerol • • • • • Brown Adipose Tissue Found mainly in newborn animals. Functions for generation of heat and consumes energy. Also common in hibernating species for their survival. Its color and heat-generating properties is due to the abundance of mitochondria. 4. CARTILAGE Firm and flexible connective tissues; hard yet flexible tissue supports structures Cells called chondrocytes lie within the lacunae, that are surrounded by a rubbery matrix that chondroblasts secret. A. Hyaline cartilages can support and cushion, resists repetitive stress. Found at the end of long bones. Hyaline cartilage-consist of cells surrounded by intercellular material containing fine collagenous fibers. Location: forms embryonic skeleton; covers ends of long bones; and forms cartilage of nose, trachea, and larynx Function: support and movement B. Fibrocartilages have tensile strength and able to absorb compressive shock. Found at the vertebral column; Contains many large, collagenous fibers in its intercellular material. Its cells are fibroblasts. Location: Intervertebral disks, pubic symphysis, and disks of knee joint. Function: Absorbs compression shock C. Elastic Cartilages maintains shape and flexibility. Found at the ear Consists of fine collagenous fibers and many elastic fibers in its intercellular material. Location: External ear, epiglottis Function: maintain a structure's shape while allowing great flexibility 5. BONE / OSSEUS TISSUE Hard and rigid tissues which forms the bones of our body. They lie within lacunae but the matrix around them is impregnated with calcium phosphate and calcium carbonate, making bones hard. Bone matrix is deposited in concentric layers around osteonic canals Location: Bones Function: Supports, protects, provides lever system for muscles to act on, stores calcium and fat, and forms blood cells. • Osteon: any of the central canals and surrounding bony layers found in compact bone • Canaliculus: any of many small canals or ducts in bone Diagram of compact bone: (a) this cross-sectional view of compact bone shows several osteons, the basic structural unit of compact bone. (B) in this micrograph of the osteon, you can see the concentric lamellae around the central canals. 5. BONE / OSSEUS TISSUE DIAGRAM OF SPONGY BONE: SPONGY BONE IS COMPOSED OF TRABECULAE THAT CONTAIN THE OSTEOCYTES. RED MARROW FILLS THE SPACES IN SOME BONES Osteogenic Cells Develop into osteoblasts Osteoblasts Bone Formation Active in making bone for growth and remodelling. They deposit bone material into the matrix which will surround them. Osteoblasts continue to live, but in a reduced metabolic state as osteocytes. Osteocytes Maintain mineral concentrations of matrix. Assist in maintenance of the bone. Osteoclasts Bone resorption active in breaking down bone for bone remodeling, providing access to calcium stored in tissues to release it into the blood. 6. BLOOD One important connective tissue aside from their cellular function of fighting against pathogens and transporting oxygen. Blood transports oxygen, carbon dioxide, nutrients, wastes, hormones, minerals, vitamins, and other substances. Erythrocyte RED BLOOD CELLS. Most abundant blood formed element, responsible for transporting oxygen to body tissues. Mammalian erythrocytes lose their nuclei and mitochondria when they are released from the bone marrow where they are made. Fish, amphibian, and avian red blood cells maintain their nuclei and mitochondria throughout the cell’s life. Leukocytes WHITE BLOOD CELLS Involved in defending the body against pathogens and foreign bodies • Neutrophils- phagocytic cells that participate in one of the early lines of defense against pathogens, • Eosinophils and basophils- help in facilitating inflammatory response • Monocytes- give rise to phagocytic macrophages which facilitates in disposal of dead and damaged cells in the body • Lymphocytes- determines the specificity of response. account for immunologic “memory,” a rapid, vigorous response to 2nd encounter with the same antigen. PREPARED BY: DMBICUA Thrombocytes PLATELETS Cytoplasmic fragments of a cell in the bone marrow which participate in the stages leading up to coagulation of the blood. Blood clots are formed in response to injury/trauma of a blood vessel. The four basic steps to coagulation are: 1. Platelets are activated by the exposed collagen 2. Platelet factors are released 3. More platelets are attracted by the platelet factors 4. Platelets come together to form a plug FIGURE 40.5BA Connective Tissue Loose connective tissue Blood Collagenous fiber Plasma 120 m 55 m White blood cells Elastic fiber Red blood cells Cartilage Fibrous connective tissue 30 m 100 m Chondrocytes Chondroitin sulfate Bone Adipose tissue 700 m Central canal Osteon Fat droplets 150 m Nuclei MUSCLE TISSUE Movement Muscle Tissue MUSCLE TISSUES • Skeletal muscle Nuclei Tissues that functions for movement. • Muscle fiber Muscle tissue consists of long cells called muscle fibers, Sarcomere 100 m which contract in response to nerve signals • There are movements that can Smooth muscle Cardiac muscle be controlled and there are not. • This is due to the different types of muscle tissues. Nucleus Muscle fibers 25 m Nucleus Intercalated disk 50 m 1. CARDIAC MUSCLE CELLS Consist of branched straited cells, each containing a single nucleus and specialized cell junctions called intercalated disks that allow ions to move quickly from cell to cell. Location: walls of the heart Function: As the walls of the heart contract, cardiac muscle propels blood into the circulation; involuntary control 2. SKELETAL MUSCLE Composed of striated muscle fibers that are long and cylindrical and contain many peripheral nuclei; makes body movement possible in vertebrates Location: In skeletal muscles attached to bones Function: Voluntary movement 3. SMOOTH MUSCLE formed of spindle-shaped cells, each containing a single centrally located nucleus. Cells are arranged closely to form sheets. These are not striated. Location: mostly in the walls of hollow organs Function: moves substances or objects along internal passageways, involuntary body activities PREPARED BY: DMBICUA Muscle Tissue TYPES OF MUSCLE TISSUES Skeletal muscle Nuclei Muscle fiber Cardiac muscle tissue- consist of branched straited cells, each containing a single nucleus and specialized cell junctions called intercalated disks that allow ions to move quickly from cell to cell. Location: walls of the heart Function: As the walls of the heart contract, cardiac muscle propels blood into the circulation; involuntary control Sarcomere 100 m Skeletal muscle tissues- Skeletal muscle tissuecomposed of striated muscle fibers that are long and cylindrical and contain many peripheral nuclei; makes body movement possible in vertebrates Location: In skeletal muscles attached Smooth muscle to bones Function: Voluntary movement Smooth muscle- formed of spindleshaped cells, each containing a single centrally located nucleus. Cells are arranged closely to form sheets. These are not striated. Nucleus Muscle fibers 25 m Location: mostly in the walls of hollow organs Function: moves substances or objects along internal passageways, involuntary control PREPARED BY: DMBICUA Cardiac muscle Nucleus Intercalated disk 50 m NERVOUS TISSUE Control NERVOUS TISSUE ▪ Controls the body as they generally function to transmit electrical signals. ▪ They make up the nervous system of most animals. ▪ It senses stimuli and transmits signals throughout the animal Location: Brain, spinal cord and nerves Function: Transmit electrical signals from sensory receptors to the spinal cord or brain, and from the spinal cord or brain to effectors Nervous tissue contains: Neurons, or nerve cells, that transmit nerve (electrical) impulses. Neurons do not undergo mitosis due to lack of centrioles. Glial cells, or glia, that help nourish, insulate, and replenish neurons. ANIMAL TISSUES