IGCSE BIOLOGY MADE BY RIANA CORDOVA NITROGENOUS ° broken down to form nitrogen How EX o C R E T O RY Excretion Removal from organisms : respiration ) ( Egestion : * toxic materials , ¥ , in excess as it is a "" "" M arteriole be cannot assimilation so they in the and are . important for blood clotting which is acid molecules amino ' . . and the ammonia is liver kidney contain be excreted to Small amount excreted . away by the blood throughout the body energy , it is wasteful for it to be excreted . as it is structures called nephrons loop down the medulla and brought There are thousands 0 capsule the renal capsule in the branch of to ' a'IEEE ' { kidneys Foiled L Afferent arteriole First coiled blood tubule & e- collecting are tangle a of blood cap - is wide . and cannot efferent arteriole is narrow get away easily High pressure . blood in glomerulus pushes against so so capillary walls walls have holes in them to let molecules ' glucose and t Nephron capillaries urea . Inside the Bowman's 0 ti on happens cortex Amino acids are too through : big to go water salts , , through . capsule and glomerulus is where filler a . Reabsorption meauua . " n.niiiiim.mn wrapped around each nephron good cap, name, that reabsorb are the use ,u, quid, and :c::::: ::: :S::::::p:::::: : :S: : :::c::::: :::c: :c salts and urea dissolved in it . pass , " " . . .. . ( Urine) - ureter /::÷/%::!i/n Reabsorbed at Component - :::::÷: on " absorbed indium amounts - - Blood passing through kidneys gets filtered and removes most of the ONLY in first coiled tubule Glucose → By active transport ; nephron has many mitochondria - salts urea as well as excess Urea . Not reabsorbed cannot take place - ° After substances have been absorbed solution of salt and water L Flows out stored for * a while Large quantities of less * kidneys urea small and L L more along urine . urea as else TH E B LA D D E R and into the bladder where it is pale yellow → a the urethra lot . of water and 0 0 0 Urine from all nephrons in the Stores urine ; has Leading closed → anywhere a . urine and exercise is . ureters → darker concentration water intake will affect temp product being released through before concentration quantities of water , urine : the final yellow / orange - little . the concentration of water in water is lost in sweat . urine . duct again cortex glomerulus glomerulus in builds up L A . of renal capsules in the cortex of each Inside the renal capsule . ill aries called the / of artery renal the tubule back up goes down to the medulla E⑧s÷÷÷ ° . ( Bowman's capsule) renal artery . → . ( broken deaminate d are split in the liver / used stored are stored Enzymes . blood and taken to " Ii::: III. broken down into small intestine for vein like fibrinogen Needed amino acids taken blood is rena, , q Hence then , afferent Loop , . are . the amino acids Because Inside the nephron 0 . . µ gag behind the intestines , : tiny million , canal and protein molecules Fi Iteration renvadin to the pelvis in sweat * urea Urea dissolves in toxic substance . Start in the cortex Carbs converted to glycogen 5) in liver . absorbed into the blood inside the are Amino acids used to build protein converted to toxic waste products of metabolism and the cortex again ' urine 4) are . Excess amino acids in the blood . ( formed and salts alimentary down ) into carbs and ammonia . kidney contains ( , urea carried to the liver through the hepatic portal . acidic an activity enzyme producing by important functions kidney tubules ) L urea water content in blood in excess ( ) , in the back of the abdomen Regulate Each form K l D N EY * Excrete ° acids amino They have two * anus product of aerobic respiration ) reducing cells excess water high concentrations Located ( waste because it dissolves in water to excrete T HE ° through in faeces containing product : - These . made in the Liver As amino acids 3) lowering pH of Kidneys from 2) . Excretion during exhalation ° food waste amino acids L carbon dioxide excrete solution excess substances urea is Protein in food taken into of metabolism kidney t Lungs 1) products of waste and undigested of Removal Egestion Lungs o PRODUCTS amino acids Animals produce nitrogenous waste formed from excess proteins and BA ' WASTE . kidney stretchy walls to out the bladder take it to the ureter hold and then to the bladder large quantities is the urethra with a . . sphincter muscle at top which is tightly - Disease q M Infection /damagµ - Accidents e- ✓ K I DN E Y in:* ::c:: :::: :c: ::n:::n: ::: : :::::÷ :::::c::::* * Inside machine blood and , dialysis fluid are separated by .si/: ina:: :ian:a./ oi:i: :n: mo:/ on.em:a: : i:ne./ partially permeable a kidney Dialysis treatment No " and water balance upset is kidney the out y kidney transplant - side of body - membrane I f - D l AL Y S IS kidneys Both - replace both kidneys - - L * Blood flows opposite to the fluid allowing exchange through concentration gradient /*:i * . are Dialysis Fluid i ::::÷:÷: ::÷: :: : " L No urea Fluid in machine continually refreshed """ " blood . * . Concentration maintained so concentration . one several :::: :::::n:: ::: : ::p: : :::: " Anticoagulant clotting is .ms/ gradients added into blood before dialysis to prevent blood . - ° No urea in fluid diffuses from blood to the dialysis fluid along → o No concentration gradient ° Movement of salts across for glucose the membrane TRANSPLANTS VS Patient to has move much around more - freedom , not connected ÷÷÷÷÷÷÷÷÷÷÷÷:÷÷÷i: procedure ° Long term solution 1mg? only work - for dialysis a limited occurs if there is an are similar in blood and fluid imbalance in concentration . . ( low This prevents salts in net movement blood / high . salts in blood ) - D l A L Y S lS . :/ ÷ ÷ ÷ ÷ ÷ ÷ :÷ 0 Risk of rejection the donor o . the concentration levels large concentration gradient Disadvantages of transplant Advantages of Transplants ° as the . / as a ' as immune foreign ' system treats substance . Not enough donors to cope with demand . Dialysis Procedure # / Hypothalamus A ° Defined L as the maintenance of Internal conditions within conc to . , glucose body ensure L If conc , . ) cells can normal asap function blood pressure , * . water , ° brought back deviate and not properly to ° o . ° They also ° environment changes have to consume more Ectothermic Animals Unable to : due to food regulate Take in temperature from surroundings . ( body temperature Made up of two dermis layers : top layer epidermis and bottom o - layer o n flat and trap less air to parts of body . it takes heat with it as lost from blood into air body distributed hairs are near surface dilate . More blood in . surface . upright which traps contract and relax very all over vasoconstriction so the body a layer of warm air for insulation to produce heat quickly This is shivering . . Heat . generated . Arterioles that supply blood to surface of the skin : and no heat is lost blood flows through Metabolism may increase to produce constricted so not much are . heat more I:÷ :÷ :÷ ÷ ÷ f NEGATIVE FEEDBACK consists of Three layers Epidermis cornified Layer contains keratin → 0 . from UV radiation conditions iea to normal a - - - :÷ ÷ ÷ ÷ :÷ ÷ ÷ ÷ ÷:÷÷÷÷÷÷÷÷i÷÷:÷ . : 0 . Blood glucose levels controlled are by negative feedback involving production of mechanism - and Dermis Blood Vessel → Temperature regulation L . Gland secretes sebum → acts as lubricant - glucagon hormones by Langerhans the islets of cells in the pancreas with two glands in one . Blood glucose falls Blood glucose rises . insulin . Hormones are made - sebaceous e- mechanism ( IGAINHEATN change from the Body too hot conditions . erial Occurs when set point and returns back effective waterproof - layer → , Metabolism slows down Muscles in the . .sn/ure'Functions- → nerves . I → hair lies heat is easily more 0 The Skin o along the . Arterioles supplying the the capillaries Vasodilation : Erector muscles contract . ) sends electrical impulses Sweat in sweat glands evaporate to cool the skin is Cold blooded animals hypothalamus , so 0 . warm blooded animals) 37°C is I . . Cold Temperatures constantly energy from respiration ( . o temperature Maintain their body Endothermic Animals : even if their CONTROL . temp Erector muscles relax means B O D Y TEMP . temperature of blood running through it Hot temperatures certain limit a If that controls body temp . body will not function , . need to be kept within of the conditions one body ( temp your etc constant internal environment a the control mechanism that keeps internal temperature constant at the centre of Contains thermo receptors that sense ° ° part of the brain # → Sweat Gland Produces sweat → - cooling agent 1) . from pancreas Insulin secreted 1) Glucagon . secreted . # Hair → Heat control → 2) - → Erector Muscle contracts → position / relaxes Stimulates the liver and muscle to control hair glycogen . cells glucose from respiration the stored 2) to convert stored glycogen into glucose . - → Receptors Detects → heat temp . and pressure 3) . stimulates liver and muscle cells to convert concentration falls to normal Blood glucose . ( polysaccharide) into . 3) Blood be regulated concentration rises to normal . - Diabetes → Has collagen Elastic Fibre → elasticity of skin # - . Dermis * o underneath the dermis is L Adipose Tissue : Oil a layer of fat called adipose tissue Made up of cells . large drops of which contain cells L 0 . body * Insulates * Energy * Provides protective 0 . type died have thought 1 Diabetes padding around organs . o of the person's to be result Hyperglycemia Hypoglycaemia : o symptoms : treatment needed) : not able to When blood as the islets of Langerhans are too system high glucose levels drop . because low no insulin can be because no glucose produced has been made . due to . Monitor As well own immune Blood glucose levels extreme thirst : are . absence of insulin reserve glucose levels blood : , blood weakness / tiredness glucose levels injecting insulin , , weight loss physical activity checking glucose . and diet conc ( affects in urine amount of insulin and exercising ( glucose ) . can be as even used for respiration . , . , Once pectin ase is broken down * juice squeezed ° Biology want we using living organisms to carry out processes to involves * * fungi Ex : Bacteria and microscopic fungi Bacteria and quickly No , are arise can plasmids to remove foods and other useful substances cloudy seem juice clearer a down regions grow , do not take up much space producing complex molecules , reproduce Milk * down . L . manipulate and lactase . lactose Many people 0 . . and easy to very small and are capable of ethical issues Easy produce larger poly - - . lactose is the sugar found in milk and lactase is it by humans to produce can be used Microorganisms * more Lactase . USE OF MICROORGANISMS L to fruits also helps saccharides like pectin makes juices make substances o ° the cell walls break more easily and . Adding pectinase * , lose the They . can be glucose lactose intoler ht become made - lactose galactose t ability to produce lactase enzyme that breaks an older in certain they get as . free by adding lactase to it allowing it and to break . Also galactose for sweets and produces glucose . . USE OF PENICILLIN USE OF YEAST 0 Making Biofuels ° * Yeast is single a sugar uses as a food source o . production of penicillin Ethanol used glucose 2) Yeast as a Ethanol * Alcohol 2C 5 Hs OH and uses the glucose for use of fossil fuels human cells industrial fernenter an Ferment ers - . . containers used to grow are produce large . broken down to so starch is amylase burns well but does not contain use carefully controlled quantities . to of exactly the right type of microorganism . respiration . . as much as energy fossil fuels so petrol is Industrial Fer mentor . sustainable resource land used anaerobic by distillation is extracted produced Disadvantage : GENETIC ENGINEERING reduce coz from air , for biofuels could be used for food instead 0 . Making Bread * harming . Advantage : present even if oxygen transgenic organism causes an organism by removing organism relieving genetic material L . Yeast is mixed with flour and water CO2 changing of genetic material of The ting individual genes from another organism Yeast will respire anaerobically if it has access to plenty of sugar L without Conditions can be ° used and treated with added for vehicle engine is . culture microorganisms in large amounts 2 CO2 t biofuel to reduce the usually is added 3) * using ethanol t carbon dioxide → Maize crop is o scale large on a o → CGH 1206 1) that Fermentation glucose ° fungus by Alexander Fleming are substances which kill bacteria Antibiotics L celled - First anti Obi tic discovered in 1928 the bread to rise Alcohol broken down and , respires anaerobically producing CO2 L . DNA of the bread bakes Ex : . changing inSer or - . said to be genetically modified or a . organism recombinant DNA . is killed as yeast , is , that now has the other organisms ' DNA is known as . Human insulin into bacteria GM crop plants , Process USE OF ENZYMES 1) Biological washing Powders ° Many ° Contain in stains on clothes are organic molecules to break down enzymes 2) . large food molecules Quickly breaking that will dissolve L L down large , insoluble molecules into smaller soluble ones , Be used to clean delicate → fabrics less energy and money which aren't suitable for high temp * Fruit juices extracted using Pectinase is added plant cell walls . plasmid from bacteria cell gene . and an breaks enzyme called down a pectinase . chemical called pectin that is found inside will want to put ( . Transformation : Recombinant DNA plasmid is inserted into If successful they of the DNA strand and to cut 4) 6) are with the trait Gene splicing takes place 5) . A used to cut the gene out are organism getting the Effective at lower temperatures organism . Restriction enzymes a the gene in 3) . Pectinas e ° identify organism B Open . Advantages L Scientists , new trait begin making when cell divides , protein it copies the develops from original an . embryonic cell of an . cell will make the DNA it 's to plasmid ) cut out gene inserted and causes foreign cell has a plasmid a part of a new it's trait new gene DNA and the foreign . gene along with it's copy of the own in own DNA so organism that all it's cells . INHERITANCE What is inheritance ? inheritance - What is genotype ? a Genotypes - Ihewmaudnsefwhpootaee9eeesticcommbat.MY to form EX : - colour What is a An organisms factors . gametes alleles called are - #µX X a letter gene that ) usually be dominant can the most seen dominant it is as recessive or father . ( XY ) . Y ( : letter lowercase ) : ( Having : ( Having different ) the when there Only same ) is dominant allele present no Heterozygous alleles two identical → Pure skin ' What is a Offspring Ratio sex-linked carrier Organism sex recessive allele for not show a trait but the trait Only able to pass What is inherited Not → Pure breeding f) chromosomes - /muesI Females * - If linked characteristic a male has have two Females X an - .. me determining the gene responsible is located : condition linked X chromosomes on a sex gender chromosome pass the gene to the → likely to inherit → came , . gene shows → daughter in chromosome X ÷ """ Gitmo more likely "" other one sex than the effect of recessive allele dominant allele that masks one similarity of the single b/c XX → . to show sex-linked recessive conditions . does If the recessive allele is at au masked they , become the carrier one dominant → . . allele that allele the ( XY ) boy PV NN ET SQUARE * that 500/0 of : 500/0 of girl ( XX ) Two different alleles www.I?da::::nm:::::anca:Yn.::7:7::: inheritance ? : y breeding , XX and XY nutrition X . . . "" X Y X - - mother ( XX ) → H . environmental and , (capital : Homozygous genotype the another - Recessive phenotype ? genetic modification to - - height physical properties Determined by - generation one . with two letters that shown Dominant , phenotypes and Alleles : two alternative forms of gene a Eye consists of genotypes information from of genetic transmission : . ? w dominance if offspring is male codominance when genes have : expressed * equally the disease he will inherit → alleles that equally are recessive . dominant both → → in a phenotype masks allele . Inherits the disease ble inherited recessive allele Codominant alleles shown with uppercase using different in genetic diagrams letters letters . EX : AB is Blood group co dominance . - What is Putten * synthesis ? * pro tiers are polymers of amino acids to translation Transcription is DNA to RNA there in humans → are ::4" I twenty amino acids Genotype - IA IA . ' ' ::: : ::: RNA " ÷::::: : :::: :: :: :: :: : :::: :: :::::: :::÷: :::: ribonucleic acid → Lt In what is DNA ? * deoxy ribonucleic * acid * * grab will they on to a ribosome to make protien a ' Nuclear division genetically identical cells 88%-1%8 ⑧⑧ * ← * since DNA is too big to travel out of the nucleus mRNA moves out nucleus Ribosome translates I used for base code , and attaches to ribosome from ribosome to fold and of reads → gene is transcribed each code acids on → the mRNA makes to mRNA three in groups of protein growth different four chromosomes of each chromosome * cells * Used for , bases codes specific amino acid ) . form final protein structure → g replacement of cells , offspring identical produces genetically parent µ asexual reproduction . → Mitosis occurs , each chromosome splits and each goes to daughter cell → During growth , exact copy is . production of gametes Reduction division Reduction Division : number is halved from chromosome diploid genetically . occurs during to increase meiosis → variation . that to ensure gametes are haploid Starts with chromosomes doubling in mitosis and lining up in the centre of the cell cells → cells divide twice . passes to each different cells , dqmeeeaged tissues ( triplet Meiosis Nuclear division that produces → p repair damaged . . replace Pnnewdn! Parent cell contains made What is meiosis ? haploid O - sequence of bases into sequence of amino Amino acid chain released f * genetically " . f : - ii : A depth detail Mitosis producing IA lo or " lo . cell division what is mitosis ? Phenotypes . to * Gametes as gamete . haploid cells → b/c of double division , meiosis produces four haploid cells . so only one copy of each chromosome . VARIATION AND NATURAL SELECTION ¥on? Continuous variation Variation has : charts * graphs ( Bell shaped ) . continuous variation a normal distribution in differences between individuals of the : situation in which there : Genes ment are can inherited change it There environ - Discontinuous Variation are several numbers Depend entirely : charts show a : the there random usually caused genes and environmental factors by both → are genetically in arranged can be , controlled an order can be measured on , and cannot be a (EX scale environmentally altered : . height , mass ) . colour blindness albinism ) , discontinuous variations are ( Ex : . gender , blood group ) . are intermediate no States . - Mutations bird develops mutation to give colorful feathers N d breeding and the of the mutation No * on passing * → when the nucleotide sequence in the DNA changes randomly : effect on the phenotype rare occas sirens protein that mutated gene → mutations lead to the , can lead to harmful * greater advantage of mating increased are ( step shaped ) . * : and graph WYNTON ? Example involved of genes genes on Genetic defects ( distribution are many intermediates . Discontinuous variation and . and - → species same changes spontaneously Mutations happen development sickle cell anaemia → and continuously works the produces of new alleles → random genetic changes phenotypes new 's gene un mutated same as . protein . small effect on → organism → gives them survival adv . . due to the factors following : . - Ionising radiation bonds and damage : change in base sequence - - * increased rates of mutation - mutagens ( Mercury chemicals types of certain : lead ) and . sickle cell Anaemia causes to strokes : lungs , blindness , kidneys , heart Risk for life acute chest syndrome , damage * Mutation changes the molecule * sickle cell tends to haemoglobin → RBC 's to become sickle causes - shaped when releasing oxygen . . threatening . Two alleles * ( get stuck in A and ) s are co narrow blood vessels dominant blocks flow of blood → A is normal → . S is sickle cell anaemia and . Carrier Mother → normal Hb ¥¥¥µ,¥ - develop → sickle HBA cue anaemia . ↳ Heterozygous carriers and Both Parents are said to be are carriers ' → ke chance they will y.at:7/EIbn.y:s.yEnhi.twu#bb..maen./qcaem.er - rant cam , Emmy nigra Abs I HBA Abs - Hon . muggy , saw - have a child one who suffers . . - WhH-aM ? Adaptive Features Fitness Hydrophytes - plants adapted to extremely wet conditions - probability : small roots Thin cuticle - Xerophytes to - extremely dry conditions - . - - - - WW Increased variation & Overproduction of offsprings need to no : Have stomata closing waxy Hairy leaves stomata on to offspring & Greater chance of survival process reproducing in its environment . ' and . water loss on : traps Individuals show * Overproduction of adaptation of offsprings Stabilizing variations . → lowers temperature fittest → → less water evaporates evaporates deep down / theory across wide of survival of the competition for characteristic → area . fittest . in genes by differences food and more resources reproduction . → allele is passed down to offspring → greater number : overtime as a result of natural selection when natural selection tends to keep populations the same . from generation to generation → change will Antibiotic resistance to Bacteria * * Baden as reproduce - Variation will of individuals with better . change in adaptive features selection plant float for photosynthesis water loss → reflects heat range of variation caused Individuals with the Evolution : : 's Charles Darwin a and surface is cooler less water seeks water * * lower : spread : transpiration evaporation for area : the in moisture underside out roots help air to quicker gas exchange from atmosphere : Cuts down surface - filled w/ : slows down : barrier : spaces both sides of stomata cuticle adapted Fittest characteristic gets The prevent hollow stem and leaves Natural selection & on organism surviving an to reproduce and survive in their environment extract nutrients easily : . passed of organisms that helps . - plants adapted inherited feature : occur quickly caused → greater by mutation chance → of evolution in might cause some a short amount of time . bacteria to be resistant to antibiotics → they do not die . occur it environment changes . .FI:5/n.a:. an.w. .n i:s. . .u natural * An example of Selection * WeA¥ng ? Selective * * Tumi:E÷:÷:n Genes of antibiotic resistance will Breeding passed select individuals with the : process has to be be repealed for many successive to next on generations - - - increased crop yield - Hardiness to weather Better tasting fruits Large 1 Domestic - . breed new a and breeding organism them together . . with the desirable traits . . .mu. lay large eggs dogs gentle with sheep w/ good - flowers unusual chicken that - to ensure .. .. . whole population will inherit the gene → characteristic most desirable . - offspring quality nature wool Horses with fine features and are fast - AND RESPONSE COORDINATION ~ ÷ ÷ ÷¥ System consists of * central nervous system ( cws ) system Nervous all of the nerves in the impulses Nerve signals Neurons from sense carry impulses : to organs Voluntary Response CNS * Neurons have and surroundings our the nervous through long fibre ( a Axon insulated cell by a axon ) peripheral and to system nerve as which enables fatty sheath w/ bodies have dendrites nervous respond system to them . and coordinate and regulate body functions impulses . . less time to be wasted in transferring impulses . small uninsulated sections along it connects to → many other neurons ( nodes ) ( forms → a network electrical jumped impulses of connection ) ← [ !¥E÷ . node to the next qgmma.qqqzgazqq.qqqg.t . receptor cell .¥i¥i÷:÷ . ⑧$ ⑥ schwann cells one 44¥ Dendrite . Of impulse from . .in#nm.TEihg/:snt::hsm ?hzBE/÷ I . conscious : Information is sent * neurons In. sensory * * body along to make sense of system : electrical : that pass us central nervous : : the brain and the spinal chord peripheral Allows the . SENSORYNEVRONETTRELAYNEVRON.LI . MOTORNEVRONETAyhraiandt.im decision is made carry out to ( starts in the sTM pain I pressure → / Receptor involve Response the brain : does not → not aware & → Effect RESPONDED → impulses to → carries impulse to effector connects to motor neurone spinal chord receptor cells and passes impulses REFLEX PATHWAY effector will react where the stimulus essential to basic survival sends electrical detected by touch involuntary → accordingly touched to stimulus The synapse synapse junction : * between two minimum . gap between is the d : d chemical messengers the "" vesicles ② move forward bid is%km*mm f synapse neurotransmitters hi impulse arrive at and ← fuses w/ More ÷ tosynapticlett - ÷ Em L÷dd K÷÷÷h÷÷÷÷÷ ¥o÷÷¥÷¥?f? " ⑥ ③ Tuftsetranowsmnttaen condition gradient f q .ee#t.s.m::.:onnen::iomes:ea Y 585%794 ÷÷÷÷÷÷i⑧TT"Y was was .→EE .. * only place affect the messages where drugs can nervous are system chemical because ④ •¥- mem ⑤ r nwweJ impulse travels along postsynaptic U - - .tl?once7mp%7ed Far;afsEy:gt f÷ ÷ ÷ ÷ ÷ ÷ Hormones ystem * Endocrine system that glands : produce hormones * * cells or w/ receptors found inside cells cell membrane on Endocrine Glands * once good a to blood shape of the hormone to another organism get to the to plasma in bring about a change . quickly the blood stream travel around the → . in the target receptors an need to hormones response destroyed → only bind to cells with a part of one → supply bring about hormone has been used a Hormones can the have target organs to body transmit information from chemicals which : that liver are Pancreas produces hormones to regulate . as to complimentary well as such as lipase ru blood glucose levels ← digestive enzymes pancreatic amylase a'In'T " " . ( Manisa"nH , II'tm%7¥yaI¥e ' + . . " ÷" -i ±: . - oestrogen controls menstrual : cycle develops sexual characteristics and in females . Adrenaline * Fighter * f t What adrenaline does to get muscles to react our g * pupils dilate to allow also much light as information possible for . - - , Produced in situations where the causes a range of different things in the increasing blood glucose concentration Increasing pulse rate t breathing gum , you aimed towards be in body may rate or flight : increase respiration in muscle cells glucose → mu, yes . fight to prepare for body → danger t oxygen delivered oxygen is , cam ed . me . to muscle cells quickly for respiration t cos taken more quickly . , # COORDINATION THE EYE : - Whory Erg and? Receptors detect : a Sensory organs specialized cells that change in the environment and stimulate impulses in - - response . - Structure t function of - Eye - skin : : group of receptors that respond to specific stimuli a sensitive to pressure Tongue Ear contains : : , temperature and pain chemicals in food t sound and movement cornea : transparent drink → touch and temperature → Iris : taste → hearing lens that retracts controls how much t light entering eye light enters pupil . Accommodation bring hens : fine the elastic can , on change shape - ligament - Muscles cause the - suspensory : Radial muscles contract circular muscles relax is attached area More light enters the eye - light T §⑧q_ ÷aEsTgPFne7 ciliary muscles relax suspensory ligaments pulled Pupil contracts less sight retina .. : .. . - circular muscles contract - smell → £ enters the eye - Rods and - - - ciliary muscles contract slack suspensory ligament lens are fat lens are thin cones receptor : cells sensitive to dim light → found all over retina where the retina to the and there are . radial muscles relax - eight → muscles that change : - Pupil dilates Rods Blind spot . lens focusing depending ciliary way : : chemicals in air . . - Eye : ¥¥* .is'¥:9¥÷¥÷÷¥ao! *÷÷ his . ÷÷÷÷÷÷÷÷÷÷ - Nose balance :÷÷: :: : ::: :c::÷::÷ brain - - - - . optic no rod nerve cells found cones : fovea : receptor cells that area on retina → distinguish color in almost where all bright light cone cells are → found 3 types that are colour sensitive ( red , blue and green ) HUMAN REPRODUCTION Fertilisation Whwin ? Gametes : sex cells adaptations ( have the male development of embryo) ammonium immature em released each egiau.msg.im takes nuclei to create gamete a Egg Aarne ( contains enzymes to digest jelly zygote . Cell cells ( telly coating . that forms a barrier after fertilisation to prevent other sperm cells ) t§⑨&¥§zizz coat of egg cell membrane) mitochondrion peace in the Iain C- Membrane - ¥Lnauids qqgeg← . • * and female gamete chances of fertilisation and to increase * fusion of the : Sperm cells ifeng.gg/ her movement ) .Jgfpµ . I FEI .FI:S:Firing the zygote ) Atsc www.FIagellu-m My # e ( swim How does the # Embryo : unborn fetus form ? * After fertilisation offspring Gestation time : period of remaining gestation * Amniotic embryo in the * Embryo * First development abdomen time travels to the uterus zygote → three a day period which the in zygote will divide several times to form an implants then 12 weeks itself in the thick * lining for the major development of organs embryo gets nutrients → of the uterus then grows and develop es → → gestation period nutrients taken from the is nine months mother . by diffusion through uterus . organs all in peace are placenta formed → embryo → fetus is now . fetus to mother 's protects fetus → the . fetus → . cushions sac , . lining * bigger in the oviduct # process of development grows c egg ) to , * Telus surrounded by . * amniotic 's join Umbilical chord sac 's blood plasma filled with amniotic fluid made from mother → fetus 's blood supply to placenta exchange of → nutrients t . removal of waste products . The placenta * worth → → * remembering waste Nutrients : fats : , → substances urea water Movement of molecules diffusion gradients * two substance difference Oz t by occurs in cone . After birth : uterus wall on molecule sire ) gaining develops by glucose amino acids , vessels connects to and from the * fetus 's blood * Mother's blood absorbs waste * Placenta is diffusion by having from fetus 's blood , fats , 's blood water and oxygen from mother placenta via umbilical chord that in the placenta so large surface area . . don't accumulate in high concentrations they . adapted to * Acts * umbilical * Placenta is removed to a barrier as prevent toxins and a thin wall t pathogens entering fetus 's blood . . . placenta detaches from → pushed out due to contractions Fetus . Not all toxin molecules are stopped ( depends * CO2 t . chord is out → after baby afterbirth is born ( does not hurt → no ) nerves → tied to prevent bleeding . Breastfeeding * * During pregnancy After birth → mammary glands enlarged mother will → be become prepared to secrete milk t stimulated to release milk due to sucking action of the - right nutrients in right amounts - the - baby - - - mother t bond at breast . Disadvantages easily to the - meows father t postnatal → to bond - Risk of infection increased bottles Allows mother - Responsibility baby more freedom - t equipment not → it sterilized expensive with the mother the Antenatal * baby not come depression → infection prevents Does mother contains antibodies baby Advantages Disadvantages Advantages . Bottle feeding Breastfeeding Whwe? . Diet : : ( before birth ) take * Exercise * Health : to name is given to the care and advice given to expectant mothers folic acid to prevent development issues with the fetus stay fit precautions : t importance of balanced diet . avoiding infections , tobacco , alcohol , nicotine , drugs along . with checks . on fetal growth and development . HUMAN SEX HORMONES Whdary Sexual oestrogen sex : hormone in * Emotional changes also changes that : controlled by release of hormones * girls characteristics sexual secondary M¥4.4 ? occur occur during puberty . temall mood → swings t more interest Breasts develop - sex : hormone in in boys opposite gender menstrual . - Hips get - cycle begins muscles develop - voice - I * * t natural change that occurs in the female g- - * Starts in * Ovulation occurs early adolescence y . days * Failure * → halfway by rise and fall of oestrogen that makes pregnancy possible . . After menstruation lining → CONNING thlmenstmal ② Egg cycle ? of - stimulating ③ Hormone develops inside FSH then egg travels down oviduct to uterus cycle causes menstruation fertilize egg to ① Pituitary gland produces follicle controlled through Whatarethehormonls : reproductive system sperm . Menstruation lasts around f- SH regular : produce # Average menstrual cycle is 28 days long cycle Menstrual cycle ? breaks Testes start to - what is the Menstrual t testes facial hair and body hair of Growth - wider penis Growth of - Body hair grows - testosterone Male . FSH to occur of uterus starts stimulates → follicle produces → to the breakdown caused by → thicken again development of oestrogen → a in . preparation in the follicle growth causes for the thick of implantation ovary and lining uterus in the next . cycle . . repair of the lining of the uterus wall t inhibits production . Oestrogen rises to high enough level → stimulates release of LH from pituitary gland → causes ovulation . A released by pituitary gland & causes egg to start maturing and ovaries to start LH : releasing Luteinising Follicle become the corpus luteum ⑤ Ovum not ⑥ If pregnancy Oestrogen Hormone levels reach fertilized → occurs → starts producing progesterone → corpus luteum breaks down maintains → progesterone levels drop t → uterus causes lining peak : corpus luteum continues to produce progesterone levels rise from day * causes uterine wall to start I to peak before thickening t day 14 preventing → . menstruation oestrogen A oestrogen ④ uterus . lining from breaking down . . egg to mature . N pituitary gland stimulated to release LH µ Causes ovulation to occur stimulates ovary to produce progesterone Progesterone : stays low from day I - 14 and starts to rise once ovulation occurs . . * Increasing levels * Decreasing cause uterine lining to thicken further → continues through pregnancy until placenta has developed . t levels causes uterine lining to break down → causing menstruation . . #