PREDISPOSING FACTORS DISEASE PROCESS LEGEND: Leads to SIGNS AND SYMPTOMS PREDISPOSING FACTORS Age: 74 years old Build-up of plaque in the coronary artery Rupture of plaques without complete arterial occlusion (pre-infarction angina) Subsequent Thrombus Formation Obstruction / occlusion in the arteries Decreased oxygen supply to the coronary artery Increased cardiac demand for oxygen Imbalance between myocardial oxygen supply and demand Anaerobic Respiration Cardiac Muscle Tissues are Deprived of Oxygen Decreased Cardiac Function with Compensatory Mechanism Decreased Ejection Fraction of the Left Ventricle Decreased total blood circulation in the body Decreasing blood pressure Progressive Weakness Loss of consciousness Cyanosis Cool Skin Shortness of breath Cellular Injury Occurs Thready Pulse Ventricular Tachycardia Hypotension Lactic Acid Production Subsequent Cellular Necrosis (Infarction) of the affected part of the Heart Chest Pain, Weakness Pooling and backing up of blood in the legs, ankles, and feet