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Administering a Blood Transfusion

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SKILL
15-6
Administering a Blood Transfusion
A blood transfusion is the infusion of whole blood or a blood component such as
plasma, red blood cells, or platelets into a patient’s venous circulation (Table 15-1).
Before a patient can receive blood, his or her blood must be typed to ensure that he or
she receives compatible blood. Otherwise, a serious and life threatening transfusion
reaction may occur involving clumping and hemolysis of the red blood cells and death
can occur (Table 15-2).
Equipment
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Blood product
Blood administration set (tubing
with in-line filter and Y for saline
administration)
0.9% normal saline
IV pole
IV catheter (gauge or larger)
Clean gloves
Tape
Assessment
Obtain a baseline assessment of the patient, including vital signs, heart and lung sounds, and
urinary output. Review the most recent laboratory values, in particular, the complete blood
count (CBC). Ask the patient about any previous transfusions, including the number he or
she has had any reactions experienced during a transfusion. Inspect IV insertion site, noting
that the gauge of the IV catheter is an 18 or larger, and check the type of solution being
given.
NURSING
DIAGNOSIS
Determine the related factors for the nursing diagnoses based on the patient’s current
status. Appropriate nursing diagnoses may include:
 Risk for Injury
 Deficient Fluid Volume
 Excess Fluid Volume
 Ineffective Peripheral Tissue Perfusion
 Decreased Cardiac Output
SKILL
15-6
Administering a Blood Transfusion(continued)
IMPLEMENTATION
ACTION
RATIONALE
1. Identify the patient. Ask if the patient is
allergic to any medication, iodine, tape, or
if the patient has had a transfusion or
transfusion reaction in the past.
Identification of the patient ensures that the
right patient receives the correct blood
transfusion. Possible allergies may exist
related to medications, iodine, or tape.
2. Determine whether patient knows
reason for the blood transfusion. Explain to
patient what will happen. Check for signed
consent for transfusion if required by
agency. Advise patient to report any chills,
itching, rash, or unusual symptoms. If the
physician has ordered any premedication,
administer it now.
Explanation provides reassurance and
facilitates cooperation. Any reactions to the
transfusion necessitates stopping the
transfusion immediately.
3. Perform hand hygiene and put on clean
gloves.
Hand hygiene deters the spread of
microorganisms. Gloves protect against
accidental exposure to the patient’s blood.
4. Hang container of 0.95% normal saline
with blood administration set to initiate IV
transfusion and follow administration of
blood.
Dextrose may lead to clumping of red blood
cells and hemolysis. The filter administration
in the blood set removes particulate material
formed during storage of blood.
5. Start IV with 18- or 19-gauge catheter if
not already present. Keep IV open by
starting flow of normal saline.
A large-bore needle or catheter is necessary
for the infusion of blood products. The lumen
must be large enough not to cause damage to
red blood cells. IV should be started before
obtaining blood in case the procedure takes
longer than 30 minutes.
6. Obtain blood product from the blood
bank according to the agency policy. Scan
for bar codes on blood products if required.
Blood must be stored at a carefully controlled
temperature (4◦C). Bar codes on blood
products are currently being implemented in
some agencies to identify, track, and assign
data to transfusions as an additional safety
measure.
7. Complete identification and checks as
required by agency:
 Identification number
 Blood group and type
 Expiration date
 Patient’s name
 Inspect blood for clots
Most states/agencies require two registered
nurses to verify information: unit numbers
match; ABO group and Rh type are the same;
expiration date (after 35 days, red blood cell
begin to deteriorate). Blood is never
administered to a patient without an
identification band. If clots are present, blood
should be returned to the blood bank.
RATINGS
SKILL
15-6
Administering a Blood Transfusion(continued)
ACTION
8. Take baseline set of vital signs before
beginning transfusion.
9. Start infusion of the blood product:
a. Prime in-line filter with blood.
RATIONALE
Any change in vital signs during the
transfusion may indicate a reaction.
Priming is necessary for blood to flow
properly.
b. Start administration slowly (no more
than 25-50 mL for the first 15 minutes of
transfusion.
Transfusion reactions typically occur during
this period, and a slow rate will minimize the
volume of red blood cells infused.
c. Assess vital signs at every 15 minutes
for the first half hour. Follow institutions
recommendations for taking vital signs
during the remainder of the transfusion.
If there had been no adverse effect during
this time, infusion rate is increased. If
complications occur, they can be observed
and the transfusion can be stopped
immediately.
d. Observe patient for flushing, dyspnea,
itching, hives or rash, or any unusual
comments.
These signs and symptoms may be early
indication of a transfusion reaction.
e. Never warm blood in a microwave. Use
a blood-warming device, if indicated or
ordered, especially with rapid
transfusions through a CVP catheter.
Rapid administration of cold blood can result
to cardiac arrhythmia.
10. Maintain the prescribed flow rate as
ordered or as deemed appropriate based
on the patient’s overall condition, keeping
in mind the outer limits for safe
administration. Ongoing monitoring is
crucial throughout the entire duration of
the blood transfusion for early
identification of any adverse reactions.
Assess frequently for transfusion reaction.
Stop blood transfusion if you suspect a
reaction. Quickly replace the blood tubing
with new tubing and 0.9% sodium
chloride. Notify physician and blood bank.
Rate must be carefully controlled, and
patient’s reaction must be monitored
frequently. If a transfusion reaction is
suspected, the blood must be stopped. Do
not infuse the normal saline through the
blood tubing because you would be allowing
more of the blood into the patient’s body,
which could complicate a reaction. Besides a
serious life-threatening blood transfusion
reaction, the potential for fluid-volume
overload exists in elderly patients and
patients with decreased cardiac function.
11. When transfusion is complete, clamp
off blood and begin to infuse 0.9% normal
saline.
Saline prevents hemolysis of red blood cells
and clears remainder of blood in IV line.
12. Record administration of blood and
patient’s reaction as ordered by agency.
Return blood-transfusion bag to the blood
bank according to agency policy.
This provides for accurate documentation of
patient’s response to the transfusion.
RATINGS
SKILL
15-6
Administering a Blood Transfusion
(continued)
The expected outcome is met when the patient receives the blood
transfusion without any evidence of transfusion reaction or complication.
The patient exhibit signs and symptoms of fluid balance, improved cardiac
output, and enhanced peripheral tissue perfusion.
EVALUATION
DOCUMENTATION
Document that the patient received the blood transfusion; include type of
blood product. Record the patient’s condition throughout the transfusion,
including pertinent data, such as vital signs, lung sounds, and the subjective
response of the patient to transfusion. Document any complications or
reactions or that the patient received the transfusion without any
complications or reactions. Document the appearance of the IV site, and the
presence or absence of redness, swelling, and pain.
Guidelines
Sample Documentation
Unexpected Situations and
Associated Interventions
Special Considerations
Patient is becoming febrile but is exhibiting no other signs of a transfusion
reaction: Notify physician. The physician may have you pause the blood
transfusion and medicate the patient with acetaminophen and an
antihistamine before resuming the transfusion. If this is ordered, flush the
IV with 3 mL of normal saline.
 Patient reports shortness of breath, and on auscultation you note crackles
bilaterally in the bases: Compare vital signs to normal vital sounds for this
patient. Obtain a pulse oximetry reading. Notify physician. The physician
may order a dose of a diuretic or may have slow the infusion. Continue to
assess the patients for signs and symptoms of fluid overload.
 Patient is febrile, tachycardic, and complaining of back pain: Patient is
having a transfusion reaction. Stop the transfusion immediately. Obtain
new IV tubing with 0.9% sodium chloride. Notify physician and blood bank.
Send blood unit, tubing, and filter to the lab.
 Blood is not fusing quickly enough: Adjust the rate with the clamp. If this
does not work, try flushing the IV with 3 mL of saline.
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Electronic infusion devices may be used to maintain the prescribed rate
but must be specifically designed for use with blood transfusion.
SKILL
15-6
Administering a Blood Transfusion
Home care agencies evaluates patients who are candidates for blood
transfusion at home.
 Home transfusion is not appropriate for patients who are actively
bleeding, require more than 4 hours for the transfusion, or recently had a
reaction to a blood transfusion. Written consent must be obtained from the
patient and the physician.
 The nurse transport the blood product to the patient’s home in a special
cooler. The nurse and the patient’s caregiver check the serial number and
other identification together.
Home Care
Consideration
TABLE 15-1
BLOOD
PRODUCT
(continued)

Blood Products
ABO
COMPATIBILITY
RATE OF
ADMINISTRATION
FILTER
DOUBLE-CHECKED
BY 2 PEOPLE
Packed red
blood cells
Yes
1 unit over 2-3 hours;
no longer than 4 hours
Yes
Yes
Platelets
Yes (in provided
tubing)
As fast as patient can
tolerate
No
Yes
Cryoprecipitate
-
Fresh-frozen
plasma
No
IV push over 3 minutes
Recommended
Yes
No
200 mL/hr
Yes
Yes
Albumin
In tubing
provided
1-10 mL/min (5%)
0.2-0.4 cc/min (25%)
No
No
TABLE 15-2
Transfusion Reactions
REACTION
SIGNS AND
SYMPTOMS
Allergic reaction: allergy to
transfused blood
Hives, itching
Anaphylaxis
RATE OF
ADMINISTRATION
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Febrile reaction: fever
-
develops during infusion
Fever and chills
Headache
Malaise
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Hemolytic transfusion
reaction: incompatibility of
blood product
Immediate onset
Facial flushing
Fever, chills
Headache
Low back pain
Shock
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Circulatory overload: too
much blood administered
Dyspnea
Dry cough
Pulmonary edema
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Bacterial reaction: bacteria
present in blood
Fever
Hypertension
Dry, flushed skin
Abdominal pain
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Stop transfusion immediately and keep vein open
with normal saline.
Notify physician stat.
Administer antihistamine parenterally as necessary.
Stop transfusion immediately and keep vein open
with saline.
Notify physician stat.
Treat symptoms.
Stop transfusion immediately and keep vein open
with saline.
Notify physician stat.
Obtain blood samples from site.
Obtain first voided urine.
Treat shock if present.
Send unit, tubing, and filter to lab.
Draw blood sample for serologic testing and urine
specimen to the lab.
Slow or stop infusion.
Monitor vital signs.
Notify physician.
Place in upright position with feet dependent.
Stop infusion immediately.
Obtain culture of patient’s blood and return blood bag to lab.
Monitor vital signs.
Notify physician.
Administer antibiotics stat.
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