Clinical Manifestation Butterfly rash on the face Appetite loss Hair loss Fever Fatigue Photosensitivity Mouth ulcers Unexplained Fever Pericarditis Pleuritis Painful and swollen joints Chest pain upon deep breathing Swelling (edema) in legs or around eyes Raynauds phenomenon Chorea Potential complications Blood clots and inflammation of blood vessels or vasculitis Inflammation of the heart, or pericarditis Heart attack Stroke Memory changes Behavioral changes Seizures Inflammation of lung tissue and the lining of the lung, or pleuritis Kidney inflammation/ Kidney failure Nursing Assessment Diagnostic Test Antinuclear antibody titer Skin/kidney biopsy CBC BUN Erythrocyte sedimentation rate (ESR) Urine analysis Assess skin integrity. Assess patient for pain. Assess for erythematous rash which can be on the neck, face, or extremities. Assess and monitor patient’s labs. Disease Process: Systemic Lupus Erythematous (SLE) Pathophysiology: an autoimmune disease with variable clinical symptoms, multisystem inflammation, antibodies to nuclear and cytoplasmic antigens, and a remitting and recurrent history. Over 90% of SLE cases involve women, often beginning in their reproductive years. Although it mostly affects the skin, joints, kidneys, blood cells, and nervous system, it is a chronic inflammatory illness that can impact nearly any organ system. It can be indolent to fulminant, with an extensively varied presentation and course. SLE is diagnosed by a health care provider using symptom assessments, physical examination, X-rays, and lab tests. Nursing Interventions Neuro checks Pain control management/comfort measure Analgesic administration Range of motion exercises Monitor disease progression including organ involvement and complications. Provide support and guidance for managing symptoms and minimizing disease triggers. Expected Outcomes Treatments can help manage condition, no known cure. Although lupus can cause ongoing agony, there is often good news about this condition. According to lupus groups, 80–90% of individuals with lupus will have a normal life expectancy with the right care and regular clinical follow-up. The degree of the illness determines the effects of lupus. Teaching Education/discharge Medication/side effect teaching Do not rub/apply lotion to dry skin. Use mild protein shampoo. Range of motion exercises, frequent rest periods Diet (foods to avoid) Coping strategies/ disease process Referral for support group