Patient Education:
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Abx compliance
Symptoms may
diminish quickly,
education to take abx
to completion.
Take abx at same
time.
Drink eight 8-ounce
glasses of water a day
with sulfonamides.
Take with food or right
after a meal.
Skin or urine may turn
orange/yellow, this is
normal.
Increase fluid intake
by 2000mL.
Contact pcp if adverse
reaction occurs.
Indication/Mechanism of action:
• Indication: UTI, acute Otis media, ulcerative
colitis, Mafenide and silver sulfadiazine used
for 2nd and 3rd degree burns.
• Action: Bacteriostatic: slow growing because
of their ability to inhibit the activity of folic
acid in bacterial cell metabolism.
Sulfonamides
Assessment data:
Pre assessment:
• Assess patient’s general appearance and
record vital signs.
• Obtain urine cx/urinalysis, CBC, renal
function tests.
• Assess for confusion.
• Ask about allergies.
Post-assessment:
• Therapeutic response is achieved and
there is no evidence of infection.
Side effects:
5 priority reactions:
• Anorexia
• Skin eruptions
• TEN/SJS
• Leukopenia
• Thrombocytopenia
• Aplastic anemia
1 adverse reaction:
• Conjunctivitis
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Nursing Considerations:
Sulfonamides should be used
with caution with patients
with renal/hepatic
impairment and bronchial
asthma.
Pregnancy has not been
established.
Anticoagulants: increased r/f
bleeding.
Methotrexate: increased r/f
increased bone marrow
suppression.
Hydantoins: increased r/f
increased serum hydantoin
level
Sulfonamides can cause
hypoglycemia effect with DM
patients.