Ongoing assessment #3
Student ________________________
1. (0.4) Mark the statement is true or false. Red cell formation is increased:
A. In blood donors 5-7 days after a blood donation. ____
B. In patients with hemolytic anemia. ____
C. By giving injections of erythropoietin to nephrectomized (surgically removed kidneys) patients. ____
D. In patients who have a raised blood reticulocyte count. ____
2. (0.4) Mark the statement is true or false. Vitamin B12 deficiency may:
A. Result from disease of the terminal part of the ileum. ____
B. Result in anemia with small RBCs well filled with hemoglobin. ____
C. Can be caused by gastric mucosa atrophy. ____
D. Cause a reduction in the circulating platelet level. ____
3. (0.1) Which one of the following statements is correct?
a. About 100 mg of iron is absorbed per day
b. Iron is absorbed rapidly from the small intestine
c. Iron is transported in the blood bound to transferrin
d. In general, iron must be oxidized from the ferrous to the ferric state for efficient absorption
e. Iron present in the apple is better absorbed than that present in the meat
4. (0.1) Which statement is false about iron deficiency:
A. Frequently follows persistent loss of blood from the body.
B. Is more common in women than in men.
C. May cause anemia by inhibiting the rate of multiplication of RBC stem cells.
D. May cause small pale erythrocytes to appear in peripheral blood.
5. (0.4) For each case of anaemia A–E, select the most appropriate option from the following list.
1. Iron deficiency anaemia. 2. Pernicious anaemia. 3. Normocytic anaemia. 4. Bone marrow disease.
A. RBC is normal under the microscope. The mean red cell volume is normal at 90 fl._______
B. A patient with long-standing indigestion has noticed increasing lack of energy and tiredness when walking
uphill. On questioning he has noticed that the bowel motions are unusually dark from time to time. Due to
the indigestion the patient takes a bland diet without much meat or vegetables. _______
C. A woman of 75 has noticed unusual lack of energy recently and feels she is paler than usual. Her hemoglobin
level is 11 g/dL and the red cell count is depressed. The circulating level of vitamin B12 is very low, but the
folate level is normal. _______
D. Patient is complaining or recurrent infections, tiredness, easy bleeding. Complete blood count reveals
decreased RBC, WBC and platelet count. _______
6. (0.1) Which phagocytes migrate into inflammatory sites to clean up necrotic tissue, extrude digestion
products and continue to survive and function for many months?
A) Neutrophils
B) Basophils
C) Macrophages
D) Eosinophils
7. (0.1) A 65-year-old alcoholic experienced chest pain and cough with an expectoration of sputum. A blood
sample revealed that his WBC count was 21,000/μl. What is the origin of these WBCs?
A) Pulmonary alveoli
B) Bronchioles
C) Bronchi
D) Trachea
E) Bone marrow
8. (0.1) Where does the transmigration of WBCs occur in response to infectious agents?
A) Arterioles
B) Lymphatic ducts
C) Capillaries and venules
D) Inflamed arteries
9. (0.1) A 24-year-old man came to the emergency department with a broken leg. A blood test revealed his
WBC count to be 22 X 103/μl. Five hours later, a second blood test revealed values of 7 X 10 3/μl. What is
the cause of the increased WBC count in the first test?
A) Increased production of WBCs by the bone marrow
B) Release of pre-formed, mature WBCs into the circulation
C) Decreased destruction of WBCs
D) Increased production of selectins
10. (0.1) During an inflammatory response, what is the correct order of cellular events?
A) Filtration of monocytes from blood, increased production of neutrophils, activation of tissue macrophages,
infiltration of neutrophils from the blood
B) Activation of tissue macrophages, infiltration of neutrophils from the blood, infiltration of monocytes from
blood, increased production of neutrophils
C) Increased production of neutrophils, activation of tissue macrophages, infiltration of neutrophils from the
blood, infiltration of monocytes from blood
D) Infiltration of neutrophils from the blood, activation of tissue macrophages, infiltration of monocytes from
blood, increased production of neutrophils
11. (0.1) A 45-year-old man presents to the emergency department with a 2-week history of diarrhea that
has gotten progressively worse during the past several days. He has minimal urine output and is admitted
to the hospital for dehydration. His stool specimen is positive for parasitic eggs. Which type of WBC would
have an elevated number?
A) Eosinophils
B) Neutrophils
C) T lymphocytes
D) B lymphocytes
E) Monocytes