1. Chymotrypsin (and pepsin) is specific for peptide bonds containing: (lecture 8-17)
A. Uncharged amino acid residues (aa containing aromatic rings)
B. Acidic amino acids
C.
D.
E.
Basic amino acid (trypsin: aa containing basic side chains)
Small amino acid residues
Only between Arg and Lys
2. The end product of protein digestion in gastrointestinal tract is: (lecture 8-39)
A. Dipeptide
B. Tripeptide
C. Polypeptide
D. Amino acid
E. Oligopeptide
3. Salivary lipase hydrolyses the ester bond at:
A. Position 1 of triglycerides
B.
C.
D.
E.
Position 2 of triglycerides
Position 3 of triglycerides
All of these
b and c
4. Salivary lipase converts dietary triglycerides into: (lecture 8-34)
A. 1, 2-diglycerides and fatty acids
B.
C.
D.
E.
Monoglycerides and fatty acids (pancreatic lipase + colipase)
Glycerol and fatty acids (intestinal lipase + bile acids)
All of these
1,3-diglycerides and fatty acids (X)
5. Pancreatic lipase requires for its activity: (lecture 8-26)
A. Co-lipase
B. Bile salts
C. Phospholipids
D.
E.
All of these
only a and c
6. Pancreatic lipase converts triacylglycerols into: (lecture 8-27) (FFA+2MAG)
A. 2, 3-Diacylglycerol
B. 1-Monoacylglycerol
C. 2-Monoacylglycerol
D. 3-Monoacylglycerol
E. 1, 2-Diacylglycerol
7. Co-lipase is a: (lecture 8-32)
A. Bile salt
B. Protein
C.
D.
E.
Vitamin
Phospholipid
Enzyme
8. Intestinal nucleosidases act on nucleosides and produce: (lecture 8-35)
A. Purine base only
B. Phosphate only
C. Sugar only
D. Purine or pyrimidine bases and sugars
E. Pyrimidine bases only
9. Which one of the following proteolytic enzymes is activated by acid hydrolysis of the proenzyme form:
(lecture 8-15,16)
A.
B.
C.
D.
E.
Carboxypeptidase (procarbosypeptidases + trypsin)
Pepsin (pepsinogen)
Chymotrypsin (chymotrypsinogen + trypsin)
Elastase (proelatase + trypsin)
Trypsin (trypsinogen + enteropeptidase)
10. Which of the following proteins is responsible for secretion of pancreatic juice into the intestine:
A.
B.
C.
D.
E.
Cholecystokinin
Gastrin
Insulin
Intrinsic factor
Secretin
11. Which of the following conditions can be associated with the malabsorption of iron: (lecture 7-84))
A. Anemia
B. T etany
C.
D.
E.
Hyperchylomicronemia
Porphyria
Hemophilia
12. Dipeptides are hydrolyzed by specific enzymes: (lecture 8-6,7,8)
A. That are secreted by the duodenum (ileum)
B. Inside mucosal cells of the small intestine
C. In gastric juice
D. Secreted by the pancreas
E. Activated by trypsin
13. Concerning pernicious anemia: (lecture 8-9/7-66)
A. It is caused by an inadequate intake of vitamin B12
B. Vitamin B12 is identical with “intrinsic factor” of gastric juice
C.
D.
E.
The hemopoietic failure is due to overproduction of a specific mucoprotein
The gastric juice of patients contains no “intrinsic factor”
band
14. After digestion of a piece of cake that contains flour, milk, and sucrose as its primary ingredients, the
major carbohydrate products entering the blood are: (lecture 8-22)
A. glucose
B. fructose and galactose
C. galactose and glucose
D. fructose and glucose
E.
glucose, fructose and galactose
15. Absorption of fructose: (lecture 8-23,25)
A.
B.
C.
D.
E.
is Na+ - dependent
proceeds similarly to the transport of glucose
requires ATP hydrolysis
is an example of facilitated-diffusion type of monosaccharide transport system
is H+-K* + dependent
16. Digestive enzymes such as pepsin, trypsin, and chymotrypsin are synthesized as inactive precursors.
These precursors of the active enzymes are termed: (lecture 8-7,13)
a) kinases
b) inducers
c) zymogens
d) phosphatases
e) isozymes