abirb.com/test 1. Which assessment findings would the health care provider consider as most indicative of acute renal failure? A. Alterations in blood pH; peripheral edema abirb.com/test B. Increased nitrogenous waste levels; decreased glomerular filtration rate (GFR) C. Decreased serum creatinine and blood urea nitrogen (BUN); decreased potassium and calcium levels D. Decreased urine output; hematuria; increased glomerular filtration rate (GFR) abirb.com/test Answer: B Rationale: The hallmark of acute renal injury is azotemia, an accumulation of abirb.com/test nitrogenous wastes such as creatinine, urea nitrogen, and uric acid plus a decrease in the GFR of the kidneys. While pH alterations, edema, electrolyte imbalances and decreased urine output may accompany acute renal failure, they are all potentially abirb.com/test attributable to other pathologies. Creatinine, GFR, and BUN would be unlikely to rise during renal failure. Question format: Multiple Choice Chapter 34: Acute Kidney Injury and Chronic Kidney Disease abirb.com/test Cognitive Level: Analyze Client Needs: Physiological Integrity: Physiological Adaptation Reference: p. 892 abirb.com/test 2. Which teaching points about acute tubular necrosis (ATN) should the renal nurse educator include in the orientation session of new nurses? A. "The cardinal signs of ATN are oliguria and retention of potassium, creatinine and abirb.com/test sulfates." B. "Ureteral and bladder outlet obstructions are often contributors to ATN." C. "Trauma, burns, and major surgery are common precursors to ATN." D. "Tubular epithelial cells are sensitive to ischemia andabirb.com/test toxins, and damage is irreversible." Answer: C abirb.com/test Rationale: ATN is often preceded by major surgery, burns, or trauma. Many cases of ATN are nonoliguric, and obstructions that are postrenal in nature are not common causes of ATN. Damage to tubular epithelial cells is not necessarily abirb.com/test irreversible. Question format: Multiple Choice Chapter 34: Acute Kidney Injury and Chronic Kidney Disease abirb.com/test Cognitive Level: Apply Client Needs: Physiological Integrity: Reduction of Risk Potential Reference: p. 892 abirb.com/test 3. Which clients scheduled for an interventional radiology procedure requiring administration of radiocontrast dye would be considered high risk for nephrotoxicity? Select all that apply. A. Adolescent with severe abdominal pain abirb.com/test abirb.com/test WWW.THENURSINGMASTERY.COM abirb.com/test B. Young adult with a history of glomerular nephritis who is reporting severe flank pain C. Middle-aged adult with diabetes undergoing diagnostic testing for new-onset abirb.com/test proteinuria D. Adult with elevated liver enzymes possibly due to fatty liver cirrhosis E. Middle-aged adult undergoing biopsy for a suspicious "spot" on a chest x-ray Answer: B, C abirb.com/test Rationale: Radiocontrast media-induced nephrotoxicity is thought to result from direct tubular toxicity and renal ischemia. The risk for renal damage caused by abirb.com/test radiocontrast media is greatest in older adults and those with preexisting kidney disease, volume depletion, diabetes mellitus, and recent exposure to other nephrotoxic agents. abirb.com/test Question format: Multiple Select Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Analyze Client Needs: Physiological Integrity: Reduction of Risk Potential abirb.com/test Reference: p. 893 4. An ultramarathon runner is admitted following a day-long, 50-mile (80abirb.com/testand the urine is kilometer) race because urinary volume is drastically decreased dark red. What is the likely cause of the red urine? A. Hematuria B. Hemoglobinuria abirb.com/test C. Myoglobinuria D. Kidney bleeding Answer: C abirb.com/test Rationale: Myoglobinuria, which can cause acute tubular necrosis via intratubular obstruction, involves the leaching of myoglobin from skeletal muscle into the urine, bypassing the usual filtration by the glomerulus. Excess abirb.com/test exercise and muscle trauma can contribute. While both hemoglobinuria and myoglobinuria discolor the urine, hemoglobinuria results from hemolysis following a reaction to a blood transfusion, whereas myoglobinuria involves muscle damage. abirb.com/test Question format: Multiple Choice Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Analyze abirb.com/test Client Needs: Physiological Integrity: Physiological Adaptation Reference: p. 892 5. Following the diagnosis of acute renal failure, the nurse knows that one of the abirb.com/test earliest manifestations of tubular damage is which laboratory/diagnostic result? A. Elevated blood urea nitrogen (BUN) B. Serum creatinine elevation C. Inability to concentrate urine abirb.com/test D. Reduced glomerular filtration rate abirb.com/test WWW.THENURSINGMASTERY.COM abirb.com/test Answer: C abirb.com/test Rationale: Urine tests that measure urine osmolality, urinary sodium concentration, and fractional excretion of sodium help differentiate prerenal azotemia, in which the reabsorptive capacity of the tubular cells is maintained, from tubular necrosis, in which these functions are lost. One of the earliest manifestations of tubular damage abirb.com/test is the inability to concentrate urine. Conventional markers of serum creatinine and urea nitrogen, fractional secretion of sodium to assess glomerular filtration rate (GFR), and urine output do not manifest for 1 to 2 days after the acute renal failure has begun. abirb.com/test Question format: Multiple Choice Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Understand abirb.com/test Client Needs: Physiological Integrity: Physiological Adaptation Reference: p. 892 6. A health care provider for an obese male who has a history of diabetes and abirb.com/test hypertension reports that the client's glomerular filtration rate (GFR) is 51 mL/min with elevated serum creatinine levels. Which statement by the health care provider will likely answer the client's question about the result? abirb.com/test A. "We will regularly monitor your kidney function, but most likely your kidneys will be able to compensate on their own and intervention is not required." B. "You likely have chronic kidney disease and there may be urine in your blood until it is controlled." abirb.com/test C. "Your chronic kidney disease has likely been caused by your diabetes and high blood pressure." D. "You are in kidney failure and I will be starting dialysis treatment immediately." abirb.com/test Answer: C Rationale: Diabetes and hypertension are conditions that can cause chronic kidney disease (CKD). While the kidneys do have a remarkableabirb.com/test ability to compensate for impaired function, this fact does not mean that treatment would not be undertaken. Hematuria is not a common manifestation of CKD. The client's GFR of 51 mL/min does not indicate kidney failure or the need for dialysis. abirb.com/test Question format: Multiple Choice Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Analyze abirb.com/test Client Needs: Physiological Integrity: Physiological Adaptation Reference: p. 895 7. A nurse is collecting a urine specimen prior to measuring the albumin level in a abirb.com/test client's urine. A colleague states, "I thought albumin was related to liver function, not the kidney." How can the nurse best respond to this statement? A. "Urine should normally be free of any proteins, and albumin is one of the more common proteins to be excreted in chronic renal failure." abirb.com/test B. "Urine albumin levels are useful for diagnosing diabetic kidney disease." abirb.com/test WWW.THENURSINGMASTERY.COM abirb.com/test C. "A urine dipstick test will tell us exactly how much albumin is being spilled by the kidneys." D. "A urine test for albumin allows us to estimate the glomerular filtration rate quite abirb.com/test accurately." Answer: B abirb.com/test Rationale: In clients with diabetes, albumin tests are a useful adjunctive test of nephron injury and repair. Urine is not normally completely free of proteins and a urine dipstick does not allow for the quantification of how much albumin is in a sample. Albumin tests do not allow for an accurate indirect indication of glomerular abirb.com/test filtration rate. Question format: Multiple Choice Chapter 34: Acute Kidney Injury and Chronic Kidney Disease abirb.com/test Cognitive Level: Analyze Client Needs: Physiological Integrity: Reduction of Risk Potential Reference: p. 896 abirb.com/test 8. Which clinical manifestations would lead the nurse to suspect that a client with renal failure is developing uremia? Select all that apply. A. Weakness and fatigue. abirb.com/test B. Lethargy and confusion. C. Extreme itching. D. Blood in urine. E. Urine smell in the stool. abirb.com/test Answer: A, B, C Rationale: Uremia affects all body systems. The symptoms at the onset include abirb.com/test weakness, fatigue, nausea, and apathy. These are subtle signs. More severe symptoms include extreme weakness, frequent vomiting, lethargy, and confusion. Pruritis often accompanies the uremic state as well. The term uremia literally means "urine in the blood"; however, it does not cause abirb.com/test the appearance of blood in urine (hematuria). There is no direct effect on the gastrointestinal system, so the smell of stool does not change. Question format: Multiple Select abirb.com/test Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Analyze Client Needs: Physiological Integrity: Reduction of Risk Potential abirb.com/test Reference: p. 900 9. Which diagnostic bloodwork is most suggestive of chronic kidney disease (CKD)? A. A client with high pH, low levels of calcium, and low levels of phosphate abirb.com/test B. A client with low vitamin D levels, low calcitrol levels, and elevated parathyroid hormone (PTH) levels C. A client with low bone density, low levels of calcium, and low levels of phosphate D. A client with low potassium levels, low calcitriol levels, and increased parathyroid abirb.com/test hormone (PTH) levels abirb.com/test WWW.THENURSINGMASTERY.COM abirb.com/test Answer: B abirb.com/test Rationale: CKD is associated with low vitamin D and calcitrol levels, which induces increased PTH production. CKD is also associated with acidosis (low pH), high levels of phosphate and hyperkalemia. Question format: Multiple Choice abirb.com/test Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Analyze Client Needs: Physiological Integrity: Physiological Adaptation Reference: p. 898 abirb.com/test 10. Which medication would the nurse anticipate being prescribed for the client with renal failure who has hyperphosphatemia? abirb.com/test A. Vitamin D (Calcitriol) B. Calcium carbonate C. Levothyroxine D. Cinacalcet abirb.com/test Answer: B Rationale: Phosphate-binding antacids (aluminum salts,abirb.com/test calcium carbonate, or calcium acetate) may be prescribed to decrease the absorption of phosphate from the gastrointestinal tract. Question format: Multiple Choice abirb.com/test Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Apply Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies Reference: p. 899 abirb.com/test 11. To maintain hematocrit levels in clients with kidney failure, the nurse should be prepared to perform which intervention? abirb.com/test A. Arrange for frequent blood transfusions in an outpatient clinic. B. Administer iron dextran intravenously. C. Administer a subcutaneous injection of recombinant human erythropoietin (rhEPO). abirb.com/test D. Administer prenatal vitamins twice a day. Answer: C abirb.com/test Rationale: Recombinant human erythropoietin (rhEPO) helps maintain hematocrit levels in people with kidney failure. Secondary benefits include improvement in appetite, energy level, sexual function, skin color, hair and nail growth, and abirb.com/test reduced cold intolerance. Blood transfusion is a treatment if symptomatic with low hemoglobin; however, the health care provider will try to prevent this by giving EPO. IV iron dextran is for severe iron-deficiency anemia and may be used as part of the treatment of anemia in chonic kidney disease butabirb.com/test is not the first choice for abirb.com/test WWW.THENURSINGMASTERY.COM abirb.com/test iron supplementation. Prenatal vitamins are high in vitamins but not designed for clients with renal failure. Question format: Multiple Choice abirb.com/test Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Apply Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies Reference: p. 899 abirb.com/test 12. A nurse is performing client education with an adult recently diagnosed with chronic kidney disease. Which statement by the client would the nurse most likely want to correct or clarify? abirb.com/test A. "I will be prone to anemia, since I am not producing as much of the hormone that causes my bones to produce red blood cells." B. "My heart rate might go up because of my kidney disease and my blood might be abirb.com/test a lot thinner than it should be." C. "My kidney problems increase my chance of developing high blood pressure or diabetes." D. "I will have a risk of either bleeding too easily or possibly clotting too quickly, abirb.com/test though dialysis can help minimize these effects." Answer: C abirb.com/test Rationale: While high blood pressure can be causative of—or consequent to—renal failure, diabetes is not normally a result of existing chronic kidney disease. Persons with renal failure are indeed prone to anemia, increased heart rate, decreased abirb.com/test blood viscosity, and coagulopathies. The risk of bleeding and thrombotic disorders can be partially mitigated by dialysis. Question format: Multiple Choice Chapter 34: Acute Kidney Injury and Chronic Kidney Disease abirb.com/test Cognitive Level: Apply Client Needs: Physiological Integrity: Physiological Adaptation Reference: p. 898 abirb.com/test 13. The nurse assesses a client with renal failure for encephalopathy caused by uremia. Which clinical manifestation will the nurse likely find? A. Severe chest pain with pericardial friction rub on auscultation. abirb.com/test B. Stiff immobile joints and contractures. C. Loss of recent memory and inattention. D. Pruritus with yellow hue to skin tone. abirb.com/test Answer: C Rationale: Reductions in alertness and awareness are the earliest and most abirb.com/test significant indications of uremic encephalopathy. These often are followed by an inability to fix attention, loss of recent memory, and perceptual errors in identifying people and objects. Chest pain and friction rub can result from uremia-related pericarditis. Joint pain is not associated with uremia. Although pruritus can occur abirb.com/test abirb.com/test WWW.THENURSINGMASTERY.COM abirb.com/test due to uremia, having a yellow hue to the skin is jaundice (which is associated with liver dysfunction). Question format: Multiple Choice abirb.com/test Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Apply Client Needs: Physiological Integrity: Reduction of Risk Potential Reference: p. 900 abirb.com/test 14. Which phenomenon contributes to the difficulties with absorption, distribution, and elimination of drugs that are associated with kidney disease? A. Reductions in plasma proteins increase the amount ofabirb.com/test free drug and decrease the amount of protein-bound drug. B. Acute tubular necrosis is associated with impaired drug reabsorption through the tubular epithelium. abirb.com/test C. Decreased retention by the kidneys often renders normal drug dosages ineffective. D. Dialysis removes active metabolites from circulation, thereby minimizing therapeutic effect. abirb.com/test Answer: A abirb.com/test Rationale: A decrease in plasma proteins, particularly albumin, that occurs in many persons with renal failure results in less protein-bound drug and greater amounts of free drug. Drug elimination problems do not stem as directly from impaired tubular reabsorption, decreased retention, or the process of dialysis. abirb.com/test Question format: Multiple Choice Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Apply Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies abirb.com/test Reference: p. 901 15. An adult diagnosed with renal failure secondary to diabetes mellitus is abirb.com/test scheduled to begin dialysis soon. Which statement by the client reflects an accurate understanding of the process of hemodialysis? A. "It is stressful knowing that committing to dialysis means I cannot qualify for a kidney transplant." abirb.com/test B. "I know I will have to go to a hospital or dialysis center for treatment." C. "Changing my schedule to accommodate 3 or 4 hours of hemodialysis each day will be difficult." abirb.com/test D. "I will not be able to go about my normal routine during treatment." Answer: D abirb.com/test Rationale: Hemodialysis requires the client to remain connected to dialysis machinery, whereas peritoneal dialysis allows for activity during treatment. Dialysis does not disqualify an individual from receiving a transplant. Dialysis does not require attendance at a dialysis center; clients can be taught to perform the dialysis abirb.com/test abirb.com/test WWW.THENURSINGMASTERY.COM abirb.com/test in their home with a family member in attendance. Hemodialysis is normally conducted 3 times weekly, not once per day. Question format: Multiple Choice abirb.com/test Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Analyze Client Needs: Physiological Integrity: Physiological Adaptation Reference: p. 896 abirb.com/test 16. Which clinical finding among older adults is most likely to be viewed as a normal part of age-related changes? A. 81-year-old client whose serum creatinine level has increased abirb.com/test sharply since the last blood work B. 78-year-old client whose glomerular filtration rate (GFR) has been steadily declining over several years abirb.com/test C. 90-year-old client whose blood urea nitrogen (BUN) is rising D. 80-year-old cliet whose dipstick urine reveals protein is present Answer: B abirb.com/test Rationale: A gradual decrease in GFR is considered a normal age-related change. Sudden increase in creatinine or BUN would warrant follow up, as would the abirb.com/test presence of protein in a client's urine. Question format: Multiple Choice Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Apply abirb.com/test Client Needs: Physiological Integrity: Reduction of Risk Potential Reference: p. 905 17. A client with hypertension, arthritis, and early chronic kidney disease (CKD) has abirb.com/test developed viral gastroenteritis and is unable to consume adequate fluids. Which prescribed medications should the nurse caution the client about taking due to the increased risk for prerenal acute kidney injury? Select all that apply. abirb.com/test A. Ramipril B. Ibuprofen C. Acetaminophen D. Amlodipine abirb.com/test E. Calcium carbonate F. Hydrochlorothiazide Answer: A, B, F abirb.com/test Rationale: While at risk for dehydration, the client should be cautioned against taking medications that can either worsen dehydration or interfere with renal blood abirb.com/test flow autoregulation. Hydrochlorothiazide, a diuretic, will promote dehydration and reduce renal blood flow. Ramipril, an angiotensin-converting enzyme inhibitor, may cause prerenal acute kidney injury in persons with decreased blood flow due to interference with efferent arteriole vasoconstriction. Ibuprofen, an NSAID, can abirb.com/test reduce renal blood flow through inhibition of prostaglandin synthesis, which abirb.com/test WWW.THENURSINGMASTERY.COM abirb.com/test prevents afferent arteriole vasodilation. Acetaminophen is not an NSAID and does not interfere with renal blood flow. Calcium carbonate is an antacid and poses no risk. Amlodipine is a calcium channel blocker that is not linked to pre-renal acute abirb.com/test kidney injury, but if the client's blood pressure were low, this medication may need to be avoided while the client is ill. Question format: Multiple Select Chapter 34: Acute Kidney Injury and Chronic Kidney Disease abirb.com/test Cognitive Level: Analyze Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies Reference: p. 901 abirb.com/test 18. A client is admitted to the hospital with acute kidney injury (AKI). Which diagnostic test will the nurse assess to best determine the cause of the AKI? A. Glomerular filtration rate abirb.com/test B. Creatinine level C. Blood urea nitrogen (BUN) or urea D. BUN:creatinine or urea:creatinine ratio abirb.com/test Answer: D Rationale: Creatinine, urea/BUN, and glomerular filtration rate may all be abnormal abirb.com/test in AKI, so alone these results do not offer as much information about the cause of AKI as examining the elevation of urea/BUN in comparison to creatinine (known as the BUN:Cr ratio). In causes that are pre-renal, the BUN:Cr ratio will exceed 20:1 (Ur:Cr greater than 100:1), which helps the heath care provider differentiate the abirb.com/test pre-renal from intra-renal causes of AKI. Question format: Multiple Choice Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Apply abirb.com/test Client Needs: Physiological Integrity: Reduction of Risk Potential Reference: p. 894 19. The nurse is planning the care for a client with acuteabirb.com/test kidney injury (AKI). What should the nurse prioritize in the client's plan of care? Select all that apply. A. Assessing fluid balance B. Monitoring electrolyte levels abirb.com/test C. Promoting infection control D. Optimizing pain control E. Protecting from falls abirb.com/test Answer: A, B, C Rationale: The nurse will need to monitor fluid balance carefully as the client can abirb.com/test experience both fluid volume excess and deficit in AKI. There are also serious consequences due to electrolyte imbalances, such as cardiac dysrhythmias related to hyperkalemia. Secondary infections are a major cause of death in people with AKI, making infection control another priority. Having AKI on its own does not abirb.com/test increase the risk for falls or cause pain in the client. abirb.com/test WWW.THENURSINGMASTERY.COM abirb.com/test Question format: Multiple Select Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Apply abirb.com/test Client Needs: Physiological Integrity: Reduction of Risk Potential Reference: p. 891 20. The nurse is caring for a group of four male clients with chronic kidney disease abirb.com/test (CKD) and coronary artery disease. The nurse will prioritize which client as being at greatest risk for angina? A. The client with electrocardiogram results indicating sinus bradycardia B. The client with a hemoglobin level of 8.0 g/dL (80 g/L) abirb.com/test C. The client with a calcium level of 8 mg/dL (2.0 mmol/L) D. The client with a blood pressure of 160/90 mm Hg Answer: B abirb.com/test Rationale: A hemoglobin level of 8.0 g/dL (80 g/L) is significantly lower than the normal lower limit for males of 14.0 g/dL (140 g/L). Thisabirb.com/test reduction in oxygencarrying capacity places the client at risk for myocardial ischemia. A mildly lower calcium level does not directly create an imbalance in myocardial oxygen supply and demand. Bradycardia reduces myocardial oxygen demand while increasing abirb.com/test supply, compared to tachycardia that can result as a compensatory mechanism in anemia. The elevated blood pressure would not result in angina. Question format: Multiple Choice Chapter 34: Acute Kidney Injury and Chronic Kidney Disease abirb.com/test Cognitive Level: Analyze Client Needs: Safe, Effective Care Environment: Management of Care Reference: p. 899 abirb.com/test 21. A 5-year-old child who had been receiving dialysis treatments has undergone renal transplant and will now be taking prednisone. The parents are hopeful the child's development and overall health will normalize. The nurse should inform the abirb.com/test parents that taking prednisone can result in some similar adverse effects as living with chronic kidney disease (CKD). Which effects should the nurse include? Select all that apply. A. Fluid retention abirb.com/test B. Increased risk for infection C. Delayed growth D. Weakened bone structure abirb.com/test E. Hypokalemia F. Increased blood glucose Answer: A, B, C, D abirb.com/test Rationale: Of the effects listed, those that are common to CKD and taking a corticosteroid medication include fluid retention, growth delays, weakening of bone structure, and increased risk for infection. Although reasons behind these effects abirb.com/test differ between CKD and corticosteroid use, the results are similar in varying abirb.com/test WWW.THENURSINGMASTERY.COM abirb.com/test degrees. Although a corticosteroid can also cause hypokalemia and increased blood glucose levels, these are not effects of CKD. Question format: Multiple Select abirb.com/test Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Analyze Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies Reference: p. 893 abirb.com/test 22. The nurse is caring for an older adult client with acute glomerulonephritis who develops sudden-onset dyspnea. The client's vital signs are: blood pressure 175/96 mm Hg; heart rate 98 bpm; respiratory rate 22 breaths/min; oxygen saturation abirb.com/test 88% on room air. What is the nurse's priority assessment? A. Breath sounds B. Electrocardiogram abirb.com/test C. Urine appearance and volume D. Level of consciousness Answer: A abirb.com/test Rationale: Given the client's report of dyspnea and low oxygen saturation level, breath sounds should be assessed to determine evidence of pulmonary edema. This immediate bedside assessment should be done prior to abirb.com/test any of the others listed, because it offers the best evidence related to a time-sensitive, likely, and lifethreatening complication of acute kidney injury in the older adult. All the other assessments are relevant and can be done once breath sounds are assessed. abirb.com/test Question format: Multiple Choice Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Analyze Client Needs: Physiological Integrity: Reduction of Risk Potential abirb.com/test Reference: p. 892 23. The nurse is monitoring a group of clients being treated for various chronic abirb.com/test illnesses. Which clients should the nurse prioritize as most at risk for hyperkalemia? Select all that apply. A. 80-year-old with left-sided heart failure taking a loop diuretic B. 76-year-old with type 2 diabetes controlled with insulin and taking an ACE abirb.com/test inhibitor C. 25-year-old with acute kidney injury taking penicillin D. 65-year-old with rheumatoid arthritis taking a corticosteroid abirb.com/test E. 55-year-old with Addison disease taking a mineralocorticoid Answer: B, C abirb.com/test Rationale: The balance of serum potassium is highly dependent on renal excretion, which is directly affected by the glomerular filtration rate (GFR); the excretion and reabsorption in the tubules is dependent on the amount of aldosterone present (i.e., the more aldosterone present, the more potassiumabirb.com/test will be excreted in urine). The client with type 2 diabetes may have a decreased GFR and taking an ACE abirb.com/test WWW.THENURSINGMASTERY.COM abirb.com/test inhibitor reduces the action of aldosterone, both increasing the risk for hyperkalemia. Though only 25 years old, having acute kidney injury means this client has a decreased GFR and thus will be at high risk for hyperkalemia. While Addison disease can cause hyperkalemia, the treatmentabirb.com/test with a mineralocorticoid will increase the loss of potassium in urine, correcting the hyperkalemia. The client with rheumatoid arthritis will also have higher levels of aldosterone activity due to the use of corticosteroids, reducing potassium levels. The client on a loop diuretic is abirb.com/test at risk for hypokalemia. Question format: Multiple Select Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Analyze abirb.com/test Client Needs: Physiological Integrity: Reduction of Risk Potential Reference: p. 858 abirb.com/test infarction. The 24. A client is in cardiogenic shock following a massive myocardial client's family asks the nurse, "Why are the health care providers recommending dialysis since its the heart that is sick?" Which response by the nurse is most appropriate at this time? abirb.com/test A. "It looks like your loved one has been exposed to nephrotoxic drugs like a nonsteroidal anti-inflammatory drug (NSAID) prior to the heart attack." B. "When a person has such a large heart attack, the kidneys suffer by developing abirb.com/test clots which interfere with urine production." C. "When a person has a large heart attack and goes into shock due to heart failure, there is a decrease in renal perfusion which allows toxins to increase in the blood." abirb.com/test D. "It looks like your family member has had a blockage in the ureters for quite some time and the heart attack has made it more difficult for the blood to be filtered by the kidney." abirb.com/test Answer: C Rationale: Prerenal acute kidney injury (AKI) is characterized by a marked decrease abirb.com/test in renal blood flow. It is reversible if the cause of the decreased renal blood flow can be identified and corrected before kidney damage occurs. Causes of prerenal AKI include heart failure and cardiogenic shock. This would call for temporary dialysis to filter the blood while the heart is healing. Intrarenal AKI is caused by abirb.com/test acute tubular necrosis due to exposure to nephrotoxic drugs or prolonged ischemia. Postrenal AKI is caused by bilateral ureteral obstruction. Question format: Multiple Choice abirb.com/test Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Analyze Client Needs: Physiological Integrity: Physiological Adaptation Reference: p. 900 abirb.com/test 25. A nurse is caring for a group of clients and reviewing the recent laboratory values and medical charts. What adult client(s) is exhibiting early manifestations of prerenal acute kidney injury (AKI), which should be reported to the health care abirb.com/test provider? Select all that apply. abirb.com/test WWW.THENURSINGMASTERY.COM abirb.com/test A. Urine output has dropped from 1200 mL/24 hours to current 300 mL/24 hours. B. Hemoglobin has dropped from 13.4 g/dL to 12.0 g/dL (134 to 120 g/L). C. Blood urea nitrogen (BUN) to creatinine ratio has gone from 10:1 to 21:1. abirb.com/test D. Glomerular filtration rate (GFR) is currently 93. E. Serum creatinine level has increased from 0.6 to 1.2 mg/dL (53 to 106 μmol/L). Answer: A, C abirb.com/test Rationale: Prerenal AKI is manifested by a sharp decrease in urine output such as 300 mL/24 hours and a disproportionate elevaltion of BUN in relation to serum creatinine levels. A normal value is 10:1, but a value of abirb.com/test 21:1 is a disporportionate elevation in the ratio. The hemoglobin level of 12.0 g/dL (120 g/L) is on the low end of normal for adults. For adults in their 50s, a GFR of 93 is normal. Serum creatinine levels are normal from 0.6 to 1.2 mg/dL (53 to 106 μmol/L). abirb.com/test Question format: Multiple Select Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Analyze Client Needs: Physiological Integrity: Physiological Adaptation abirb.com/test Reference: p. 892 26. A client in the intensive care unit is receiving a blood transfusion. The client immediately developed a reddish-color urine flowing intoabirb.com/test the Foley bag. What is likely the cause of this red urine and what priority intervention should the nurse implement? A. Hemoglobinuria indicating an acute hemolytic reaction; the transfusion must be abirb.com/test stopped immediately. B. Myoglobinuria causes urine color change and is associated with muscle destruction; call the health care provider immediately. C. Trauma to the urethra can cause blood in the urine; increase abirb.com/testthe fluid intake by increasing IV flow rate. D. Exposure to bacteria causing urinary tract infeciton with bleeding; contact health care provider for antibiotic prescription. abirb.com/test Answer: A Rationale: The onset of red urine during or shortly after abirb.com/test a blood transfusion may represent hemoglobinuria indicating an acute hemolytic reaction. The priority of the nurse is to stop the transfusion, then call the laboratory and the health care provider. Myoglobinuria causes urine color change, usually brown in color, and is abirb.com/test associated with muscle destruction. There is no indication that this occurred recently but if it occurs, the health care provider should be notified. Trauma with insertion of a catheter would cause bleeding at the time of the insertion and would not be associated with a blood transfusion. Severe kidney infections can cause abirb.com/test bleeding but this would have been evident prior to hanging/infusing the blood. Question format: Multiple Choice Chapter 34: Acute Kidney Injury and Chronic Kidney Disease Cognitive Level: Analyze abirb.com/test Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies abirb.com/test WWW.THENURSINGMASTERY.COM Reference: p. 893 abirb.com/test abirb.com/test abirb.com/test abirb.com/test abirb.com/test abirb.com/test abirb.com/test abirb.com/test abirb.com/test abirb.com/test abirb.com/test abirb.com/test abirb.com/test abirb.com/test abirb.com/test WWW.THENURSINGMASTERY.COM